113 results about "Blood outflow" patented technology

A prosthetic venous valve includes a frame and leaflets. The frame includes: (i) a generally hollow base disposed at a blood inflow end; (ii) a plurality of struts connected with the base and extending generally parallel to a direction of forward flow of blood from the generally hollow base to a blood outflow end; and (iii) inwardly oriented flanges disposed at the blood outflow ends of the struts. The leaflets are disposed in gaps between the struts and are supported by the frame. The leaflets are arranged to close into the vein lumen to substantially seal against backflow of blood from the blood outflow end to the blood inflow end. The inwardly oriented flanges of the struts enhance the sealing.

Implantable valve for treating venous insufficiency having a self-expanding frame encased in polymer having a distal section for blood in-flow, a bulbous center section and a proximal section for blood out-flow. Polymeric leaflets have proximal ends forming a valve outlet which opens and closes in response to venous blood flow and distal portions integral with the inner polymer surface of the distal end of said bulbous section. The leaflets define a predominantly biomimetic sinus region with the bulbous section. Opening of the valve induces flushing of blood from the sinus region for smooth non-traumatic blood flow through said valve.

Apparatus and methods for the extracorporeal treatment of blood are described. The apparatus includes a dialyzer which is separated into a first and second chamber by a semipermeable membrane, wherein the first chamber is disposed in a dialysis fluid path and the second chamber can be connected to the blood circulation of a patient by way of a blood inflow conduit and a blood outflow conduit, a feed for fresh dialysis fluid, a discharge for spent dialysis fluid, a measuring device disposed within the discharge for determining the absorption of the spent dialysis fluid flowing through the discharge, wherein the measuring device has at least one radiation source for substantially monochromatic electromagnetic radiation, and a detector system for detecting the intensity of the electromagnetic radiation, wherein means are provided to compensate for changes that occur in the intensity of the electromagnetic radiation of the radiation source and / or the sensitivity of the detector system.

This invention describes apical access methods and devices that enable repair, modification, removal, and / or replacement of a defective heart valve while allowing the beating heart to deliver blood flow through the defective valve annulus for an extended period of time in volumes sufficient to sustain life. The invention is comprised of a flow housing having a blood inflow opening, a blood outflow opening, and a one-way valve disposed within the flow housing between the inflow and outflow openings.

A system for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function

A prosthetic venous valve includes a frame and leaflets. The frame includes: (i) a generally hollow base disposed at a blood inflow end; (ii) a plurality of struts connected with the base and extending generally parallel to a direction of forward flow of blood from the generally hollow base to a blood outflow end; and (iii) inwardly oriented flanges disposed at the blood outflow ends of the struts. The leaflets are disposed in gaps between the struts and are supported by the frame. The leaflets are arranged to close into the vein lumen to substantially seal against backflow of blood from the blood outflow end to the blood inflow end. The inwardly oriented flanges of the struts enhance the sealing.

A method is provided for detecting filter clogging which are able to keep track of the filter clogging with precision and in detail. At least one pressure selected from the group consisting of a pressure Pa in a blood inflow portion (32a), a pressure Pv in a blood outflow portion (32b), a pressure Pf1 in a filtrate inflow portion (32c), and a pressure Pf2 in a filtrate outflow portion (32d) is measured continuously, then a variation (pressure waveform) of the pressure is analyzed, a clogging of a filter (32) is detected using the analyzed result. Thereby a clogging of a filter is detected early. As a result, it is possible to prevent from developing of the filter clogging by controlling a dosage amount of anti-coagulant properly and changing a flow rate of blood. The variation of the pressure wave may be analyzed by subjecting the variable to Fast Fourier Transform.

Method for calculating a clogging factor of a filter composed of hollow-fiber membrane, which has a blood inflow portion 32a and a blood outflow portion 32b, by passing a blood, the method including the steps of measuring at least two pressure selected from the group consisting of a pressure (Pa) in said blood inflow portion, a pressure (Pv) in said blood outflow portion, a filtering pressure (Pf1) in said blood inflow portion, and a filtering pressure (Pf2) in said blood outflow portion and calculating a filter clogging factor in vertical direction and / or a filter clogging factor in lateral direction using at least two of the measured pressures, flow rate information, biometric information (viscosity information and so on), and structure information.

A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function

A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function

A blood test apparatus having a simple constitution whereby stable measurement can be conducted by surely sampling the blood in an amount being small but sufficient for the test without placing too much burden on a patient.When a first skin contact sensor of this apparatus detects the skin, driving of a negative pressure unit is initiated (time point 166a). Thus, the skin rises and comes into contact with a second skin contact sensor (time point 166b). After piercing into the skin at time point 166c, the negative pressure supply is once ceased. Next, the negative pressure is applied again at time point 166d for a definite period of time. Thus, the opening in the skin is broadened, which facilitates the flow out of the blood (16).

A blood test apparatus having a simple constitution whereby stable measurement can be conducted by surely sampling the blood in an amount being small but sufficient for the test without placing too much burden on a patient. When a first skin contact sensor of this apparatus detects the skin, driving of a negative pressure unit is initiated. Thus, the skin rises and comes into contact with a second skin contact sensor. After piercing into the skin, the negative pressure supply is once ceased. Next, the negative pressure is applied again for a definite period of time. Thus, the opening in the skin is broadened, which facilitates the flow out of the blood.

The present application relates to a prosthetic valve prosthesis with an anchor, includes a bracket body having a passage for supplying blood flow and at least one fixing member, the fixing member isconnected with the bracket body, the fixing member includes a lower extension section and an upper extension section, one end of the lower extension section is connected with the bracket body as a fixed end, the other end of the lower extension extends proximally along the axis of the bracket body, extending distally in the opposite direction after passing through the bent region and connected tothe upper extension. The upper extension section is located on the outer side of the lower extension section, and a leaf receiving cavity is formed between the lower extension section and the upper extension section. The fixing member is further provided with a lamination device, and when the fixing member is completely released, the self-body leaf is stacked in the leaf receiving cavity. The clamping force of the fixation part of the prosthetic valve prosthesis is not influenced by the space between the stent body and the fixation part, and the influence on the blood outflow channel after thestent body is released is greatly reduced.

A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function.

The invention relates to the field of medical devices, and particularly provides a device for eliminating pathogens in blood. The device for eliminating the pathogens in the blood comprises an external circulation path consisting of a blood exhalant (1), a plasma separator (2) and a blood return pipe (3) which are sequentially connected, and further comprises a pathogen physical deactivation device (5) connected with the external circulation path. The invention further provides a method for eliminating the pathogens in the blood, comprising the following steps: after the blood flows out from a patient body, blood cells and plasma in the blood are separated by the plasma separator; and after the pathogens in the plasma are physically deactivated through the pathogen physical deactivation device, the plasma flows back to the external circulation path and then flows back to the patient body in combination with the blood cells. The method adopts physical means and can reduce side effects. The device is simple in structure, and can be connected with other blood purification devices for use.

A system for detecting and measuring increased global or local intracranial pressure includes various devices for performing controlled occlusion of jugular cranial blood outflow and generating occlusion data related to said controlled occlusion, a cranial blood outflow pressure measurement device and a processor for processing jugular cranial blood outflow occlusion data and cranial blood outflow data to identify and / or measure a functional relationship between the jugular controlled occlusion and the jugular cranial blood outflow pressure. A device communicates the functional relationship a display device and / or a patient monitoring system. The processor also detects a state of equilibrium between the jugular cranial blood outflow pressure and the jugular occlusion pressure at occlusion. In yet another embodiment, intracranial and extracranial vessel compliance is measured by NIRS system, the equilibrated using external compression bladder, and equilibrium bladder pressure is displayed as local intracranial pressure.

A blood sample container (1A) according to the present invention includes: a container body section (2) having an internal space (3) for storing initial flow blood to be used for testing; a blood inflow port (5) that allows the initial flow blood to flow in; a blood outflow port (6) that allows the initial flow blood to flow out; and an exhaust section (7) having a hydrophilic and bacteria-impermeable filter (12) that allows the air in the internal space (3) to be discharged, the exhaust section (7) being positioned at an upper end of the container body section (2) when the container body (1A) is used in a manner such that the blood outflow port (6) faces in a vertical direction and having a small-diameter tubular passage (11) that allows the air in the internal space (3) to be discharged by a predetermined amount of the initial flow blood that has flown into the passage (11).

The invention relates to a haemostatic and wound dressing containing the same. The haemostatic is a single polysaccharide or single hydrogel particle, or is prepared by combining at least one polysaccharide onto the surface of a hydrogel particle in a physical or chemical combining way by virtue of polymerization reaction or grafting reaction, or mixing the hydrogel particle with a polysaccharideparticle; and the wound dressing contains the haemostatic. The haemostatic prepared by the invention can effectively stop hemorrhea threatening life in wound, haemostasis can be realized by adhering,pressing or applying the haemostatic onto a wounded part, formation of a blood plaque at the wounded part can be sped up, and meanwhile formation of a blood clot at the wounded part can be sped up, thus preventing blood drain at the wounded part and preventing blood outflow at the wounded part.

A method for augmenting blood flow in a limb that is wrapped with a sleeve having at least one chamber for applying compression to the limb in a region generally underlying the chamber includes pressurizing the chamber to a first compression pressure and then reducing the pressure to a refill pressure. Pressure in the chamber is then sensed to determine a first venous refill time. The preceding steps are repeated a second and other times using second and other compression pressures that are different from the first compression pressure and from each other to determine second and other venous refill times. A customized compression pressure is determined by locating the compression pressure at which blood flow out of the region generally underlying the chamber is maximized by finding compression pressure at a maximum venous refill time. A compression device employing such a method is also disclosed.

A system and method for non-invasively estimating an absolute blood flow of a vascular region in a subject using optical data are provided. In some aspects, the method includes acquiring optical datafrom the vascular region using one or more optical sensors placed about the subject, and determining, using the optical data, an index of blood flow and. a blood volume associated with the vascular region. The method also includes computing a blood inflow and a blood outflow using the index of blood flow and the blood volume, and estimating an absolute blood flow using the blood inflow and blood outflow. The method further includes generating a report indicative of the absolute blood flow of the vascular region.

A device for treating blood in an extracorporeal circuit comprising a venous blood reservoir having an inlet and an outlet, and a hemoconcentrator having a first inlet connector for the blood to be treated, a second outlet connector for the outflow of concentrated blood, and a third outlet connector for the outflow of the ultrafiltered liquid, wherein the hemoconcentrator is disposed within the venous blood reservoir and the hemoconcentrator and the venous blood reservoir are integrated into a single monolithic assembly, and wherein the hemoconcentrator comprises an enclosure containing structure suitable to concentrate blood.

A method and device for reducing the damaging effects of radiant energy, blast, or concussive events includes applying pressure to at least one jugular vein to reduce the egress of blood from the cranial cavity during or before the incidence of the imparting event. Reducing blood outflow from the cranial cavity increases intracranial volume and / or pressure of the cerebrospinal fluid to reduce the risk of traumatic brain injury and injuries to the spinal column. Reducing blood outflow further increases the intracranial pressure and volume, and thereby increases the pressure and volume of the cochlear fluid, the vitreous humor and the cerebrospinal fluid to thereby reduce the risk of injury to the inner ear, internal structure of the eye and of the spinal column. In addition, increasing intracranial pressure and volume reduces the likelihood of brain injury and any associated loss of olfactory function.

A system for detecting and measuring increased global or local intracranial pressure includes various devices for performing controlled occlusion of jugular cranial blood outflow and generating occlusion data related to said controlled occlusion, a cranial blood outflow pressure measurement device and a processor for processing jugular cranial blood outflow occlusion data and cranial blood outflow data to identify and / or measure a functional relationship between the jugular controlled occlusion and the jugular cranial blood outflow pressure. A device communicates the functional relationship a display device and / or a patient monitoring system. The processor also detects a state of equilibrium between the jugular cranial blood outflow pressure and the jugular occlusion pressure at occlusion. In yet another embodiment, intracranial and extracranial vessel compliance is measured by NIRS system, the equilibrated using external compression bladder, and equilibrium bladder pressure is displayed as local intracranial pressure.

A method is provided for detecting filter clogging which are able to keep track of the filter clogging with precision and in detail. At least one pressure selected from the group consisting of a pressure Pa in a blood inflow portion (32a), a pressure Pv in a blood outflow portion (32b), a pressure Pf1 in a filtrate inflow portion (32c), and a pressure Pf2 in a filtrate outflow portion (32d) is measured continuously, then a variation (pressure waveform) of the pressure is analyzed, a clogging of a filter (32) is detected using the analyzed result. Thereby a clogging of a filter is detected early. As a result, it is possible to prevent from developing of the filter clogging by controlling a dosage amount of anti-coagulant properly and changing a flow rate of blood. The variation of the pressure wave may be analyzed by subjecting the variable to Fast Fourier Transform.

The invention provides a centrifugal blood pump which rotates stably. The centrifugal blood pump comprises a shell and an impeller installed in the shell, and the portion, right facing the center of the impeller, of the shell is provided with a locating shaft matched with a center hole of the impeller; the impeller is installed in the center of a spiral type blood channel between an upper cover and a lower cover; the upper cover and the lower cover are provided with a blood inflow pipe and a blood outflow pipe which are communicated with the blood channel respectively; blades in the impeller comprise main blades and subsidiary blades connected to the outer end of the main impellers; the main blades are uniformly distributed along the circumference of a rotor, and the included angles between the main blades and the blood rotating and circulating direction of the blood channel are obtuse angles. Through the optimized designed impeller and the relevant structural design, the centrifugal blood pump has high pumping efficiency at a low rotation speed, the blood arterial pressure is guaranteed, the low rotation speed lowers wear, the service life of the blood pump is prolonged, the energy consumption is also lowered, the cruising capability of the blood pump is improved, the low rotation speed also lowers the control difficulty of the work pressure of the blood pump, and the centrifugal blood pump is also simpler and more convenient to use and operate.

The extracorporeal blood circulating apparatus of the present invention includes: a closed-type venous reservoir having a blood storage chamber and a volume adjusting chamber that are disposed adjacently by partitioning a closed space formed by a housing; an adjusting liquid tank for storing an adjusting liquid that is connected to the volume adjusting chamber; and a blood pump that is connected to the blood storage chamber. In the housing, an inflow port for allowing blood to inflow and an outflow port for allowing blood to outflow are provided so as to communicate with the blood storage chamber, and an adjusting port for injecting and ejecting the adjusting liquid is provided so as to communicate with the volume adjusting chamber. The blood pump is connected via the outflow port, and the adjusting liquid tank is connected via the adjusting port. The closed space is partitioned by a flexible septum member so as to form the blood storage chamber and the volume adjusting chamber, and the adjusting liquid tank and the adjusting port are connected by a conduit member having a configuration that can adjust a flowing amount. Control of a blood storage amount to be most appropriate and easy adjustment are possible throughout all steps from before starting an extracorporeal blood circulation to terminating it.

This artificial lung includes: a housing; a hollow fiber membrane layer that is housed inside the housing and in which a multitude of hollow fiber membranes having a gas exchange function are integrated; a gas inflow section and a gas outflow section that employ the lumen of each hollow fiber membrane as a gas flow path and that are provided respectively on the upstream side and the downstream side of the gas flow paths; a blood inflow section and a blood outflow section that employ the outside of the hollow fiber membranes as a blood flow path and that are provided respectively on the upstream side and the downstream side of the blood flow path; a first filter member that is provided in contact with the surface of the hollow fiber membrane layer on the side of the blood outflow section and covers almost the entire surface, the first filter member having the function of capturing bubbles in the blood; and a second filter member spaced away from the first filter member and arranged between the first filter member and the blood outflow section, the second filter member having the function of capturing bubbles in the blood.

The present invention relates to a filter built into a blood purification column, and aims to dramatically improve the removal of air that gets into the column and to prevent blood activation due to air remaining inside of the column and decreased absorption performance due to decreased contact surface between blood and an absorbent. This blood purification column has an absorbent and a casing, both ends of which are open ends, and the absorbent is housed inside of the casing. Of the two ends of the casing, one is the blood inflow end and the other is the blood outflow end. A filter is arranged on the blood inflow end and / or the blood outflow end of the casing, and this filter fulfils the following conditions. (1) The opening ratio of the filter is 5-80% (2) The equivalent diameter of the openings in the filter is 1-5000μm (3) The ratio of the equivalent diameter of the openings to the average circle equivalent diameter of the gaps in the absorbent is 45% or greater.

A humor sampling implement includes a detection unit having a main frame part possessing a blood transfer channel to collect blood through a blood inflow port and transfer the blood to a blood outflow port, and a test paper for detecting glucose in the blood transferred through the blood transfer channel. The main frame part is furnished with a projection protruding in the blood transfer channel toward the blood outflow port. The blood transfer channel can be configured to include a first blood transfer channel opening to the blood inflow port and a second blood transfer channel connected to the first blood transfer channel, wherein the direction of blood transfer is different from that in the first blood transfer channel, and the projection is provided at an end portion of the first blood transfer channel on blood outflow port side so as to protrude in the second blood transfer channel.

A container for testing blood (1A) is provided with: a main container body (2) having an internal space (3) for storing an initial blood flow to be used for testing; a blood inflow port (5) that allows the initial blood flow to flow in; a blood outflow port (6) that allows the initial blood flow to flow out; and an exhaust part (7) that has a hydrophilic bacteria-impermeable filter (12), and allows air in the internal space (3) to be discharged. The container for testing blood (1A) is characterized in that the exhaust part (7) is positioned at the upper end of the main container body (2) when the blood outflow port (6) is used in such a manner as to be in the vertical direction, and has a small-diameter tubular passage (11) that allows air in the internal space (3) to be discharged after a prescribed amount of the initial blood flow has entered.