6 results about "Glucose polymers" patented technology

The invention relates to a dexmedetomidine film agent and a preparation method thereof, the prescription components of the dexmedetomidine film agent comprise dexmedetomidine or a pharmaceutically acceptable salt thereof and a film-forming agent, and the mass ratio of dexmedetomidine to the film-forming agent is 1: (20-200); the film-forming agent is glucose polymer ether. The glucose polymer ether can be a cellulose ether derivative and / or a starch ether derivative. When the glucose polymer ether is a starch ether derivative, the formula further comprises a plasticizer. The preparation method comprises the following steps: coating slurry to prepare a film, and drying; the slurry comprises the prescription components of the dexmedetomidine and water. And the obtained film agent product is stable in quality.

This invention discloses an extracellular polysaccharide DSP-1 from the shell of a deep-sea fungus, *Subseptospora*, and its applications. Didymella keratinophila The fermentation product of SCAU273 was isolated and purified to obtain an extracellular polysaccharide DSP-1. This polysaccharide has a molecular weight of 4116 Da, a bibranched structure, and is mainly composed of glucose polymers. Further studies showed that DSP-1 can enhance the activity and promote the proliferation of RAW 264.7 macrophages over a wide concentration range (25–400 μg / mL). Furthermore, at certain concentrations, it dose-dependently promoted the secretion of NO, TNF-α, IL-6, and IL-1β by RAW 264.7 macrophages, exhibiting good immunomodulatory activity against RAW 264.7 macrophages. It shows broad prospects for the production and widespread application of environmentally friendly marine biological agents.

A drug delivery method and a composition. The drug delivery method comprises bringing an active ingredient in contact with an absorption enhancer containing a glucose polymer or a derivative thereof to form a mixture, and nasally administering the mixture. Further provided are a composition containing an active ingredient and a glucose polymer or a derivative thereof, and the use of the composition.

The technology disclosed in this specification relates to carbohydrate composition comprising a plurality of glucose polymers comprising a mixture of 1-2, 1-3, 1-4, and 1-6 linkages and having a defined ratio of a sum of the 1,6 and the 1,4 linages to the 1,3. The composition made in process comprising mixing a solution comprising glucose syrup with acid and heating the solution to evaporate a portion of the liquid and then decreasing the pressure on the mixture to obtain the carbohydrate composition. The compositions can be used in conjunction with high potency sweeteners to replace nutritive sweeteners to replace for example to replace lost bulk. Also, the composition can be used to provide dietary fiber to edible compositions or are used as bulking agents.

This invention relates to the field of nanomedicine technology, and more particularly to a DNA nanodumbbell for targeted intrabacterial transport, its preparation method, and its applications. The invention provides a DNA nanodumbbell for targeted intrabacterial transport, comprising a glucose polymer, L-arginine, a photosensitizer, streptavidin, and Dum; wherein Dum is a single-stranded DNA modified with amino and biotinylate groups. This structure enables precise spatial arrangement and controllable loading of the photosensitizer, therapeutic drug, and polysaccharide, thereby playing a stepwise role in targeted bacterial delivery, phototherapy, and tissue repair. It effectively overcomes the limited targeting efficiency of traditional phototherapy within infected tissues, minimizes non-specific damage to healthy tissues during treatment, and precisely regulates the spatiotemporal sequence of tissue repair.