43 results about "Euphorbiaceae" patented technology

A chemical agent of the diterpene family obtained from a member of the Euphorbiaceae family of plants for use in the treatment of prophylaxis of prostate cancer or a related cancer or condition.

The invention discloses a tissue culture rapid propagation method for plukenetia volubilis L., also known as plukenetia volubilis, inca inchi, inca peanut and the like, is a perennial woody vine oil plant of the euphorbiaceae, and is native to the tropical rainforest of the Andes mountain area of South America. Vegetable oil squeezed from plukenetia volubilis L. seeds is regarded as the best vegetable oil in the world, and can be used for the aspects of food, health, pharmacy, cosmetics and the like. At present, the plukenetia volubilis L. seedlings are mainly cultivated through seed and cutting manner, and the problems of long period, high cost, low efficiency and the like exist, so that plukenetia volubilis L. in-vitro replantation plant is successfully obtained by taking the plukenetia volubilis L. section stem as an explant through processes of adventitious bud induction, multiplication, rootage, acclimatization, transplantation and the like, a plukenetia volubilis L. tissue culture rapid propagation technical system is established, and important significance is achieved for rapid propagation and large-area popularization of a good variety of the plukenetia volubilis L., as well as promotion of plukenetia volubilis L. industrial development.

A chemical agent of the diterpene family obtained from a member of the Euphorbiaceae family of plants for use in the treatment of prophylaxis of prostate cancer or a related cancer or condition.

The invention herein describes a procedure for organically extracting the lipophilic components from plants of the Family Euphorbaciae, specifically but not limited to the genus Croton. The extraction (CGO 110), is deplete of the normal proanthocyanidin content found in the parent material, yet retains its pharmacocological abilities and unlike the parent material, is selectively cytotoxic to cancer cells. The depletion of the proanthocyanidin components makes the product more amenable to preparations for the benefit of ameliorating both human and animal disease.

A method for culturing the new variety of soybean by distant grafting and asexual hybridization includes such steps as providing strong yam stem (or castor stem) stock, providing soybean sprout as scion, grafting the scion onto said stock, culturing, natural blossoming and fruiting, collecting the seeds, natural sowing, choosing the plants with obvious character variation, collecting their seeds, sowing, and repeating the steps until the chosen characters have stable inheritance. Its advantages are high yield and high resistance to diseases.

The invention discloses a tissue culture and rapid propagation method of Aleurites moluccana. The Aleurites moluccana is a Euphorbiaceae Aleurites woody oil plant. Currently, the Aleurites moluccana is mainly propagated wildly and naturally, propagation and seedling-raising with the tissue culture and rapid propagation method are rarely reported. The Aleurites moluccana is an often cross-pollinated plant, differences between wild seedlings are large, and propagation of seedlings with seeds is adverse to keeping of excellent properties such as the high oil content of excellent seed trees. In order to satisfy the huge demand of energy forest forestation for Aleurites moluccana seedlings, Aleurites moluccana stem segments with axillary buds are used as explants, in-vitro replantation plants of the Aleurites moluccana are obtained through processes of explant sterilization, induction culture, subculture, rooting culture, acclimatization and transplant and the like, a tissue culture and rapid propagation technical system for the Aleurites moluccana is established, and the method has the important significance for promotion of rapid development of the biomass energy industry.

The invention relates to a separation and purification method for ingenol monomers, and belongs to the technical field of the separation and purification for the active ingredients of traditional Chinese medicines. The separation and purification method disclosed by the invention comprises the following steps: by taking the traditional Chinese medicine moleplant seeds of euphorbia as raw materials, performing ethanol solution extraction, ethyl acetate extraction, silica-gel column chromatography, methanol dissolution and filtration, preparative high-performance liquid chromatographic separation and product recovery to obtain ingenol monomer products. According to the separation and purification method disclosed by the invention, the content of ingenol in the products achieves more than 98% by virtue of the optimum process and parameter conditions; the whole technical process is stable, simple and convenient to operate, high in separation efficiency, and low in cost, and is capable of separating and preparing the ingenol monomers with a high purity.

The invention discloses a Euphorbiaceae plant active substance and a preparation method and application thereof. The active substance is obtained by subjecting a Euphorbiaceae plant to extraction with ethanol; the active substance can be further prepared through extraction with hexane and / or ethyl acetate and / or n-butanol and may be lupeol and / or stigmasterol. The invention further discloses application of the Euphorbiaceae plant active substance in preparation of antiviral drugs for animals.

The invention belongs to the field of natural organic chemistry and relates to a preparation method of jolkinolide B. In the invention, dry roots of a plant, Euphorbia fischeriana Steud, belongs to Euphorbia in Euphorbiaceae are employed as a raw material, which is subjected to the processes including crushing, solvent extraction, organic solvent extraction, macroporous adsorption resin column chromatography, polyamide resin column chromatography, organic solvent extraction, drying and the like so as to produce the jolkinolide B. The method, compared with conventional methods for enriching the jolkinolide B, has simple processes and low cost, is increased in product yield on the basis of medicine, and has good industrial adaptability.

The cultivating method of Euphorbia plant includes the following steps: 1. treating bamboo tube through soaking in sulfuric acid solution for sulfurization, soaking in ammonia water for nitrizing, and baking; 2. filling the bamboo tube with organic fertilizer, coating the bamboo tube with plastic film, setting seeds of Euphorbia plant in small holes on the bamboo tube, sealing the holes with mud or organic fertilizer, and soaking in water; and 3. setting the bamboo tube in soil for cultivating. The method of the present invention is suitable for cultivating Euphorbia plant in desert area and has low investment and high Euphorbia plant survival rate.

Taking leaves of cleidion brevipetiolatum of Cleidion of Euphorbiaceae as raw material, the invention provides a preparation method, a detecting method and use of high purity cleidion brevipetiolatum glycoside A. The preparation method includes the steps of smashing leaves of the cleidion brevipetiolatum of the Euphorbiaceae, heating though alcohol for reflux extraction, achieving chromatography for ethanol extract through a silicagel column, eluting through chloroform-carbinol mixed solvent, detecting through thin-layer chromatography, collecting eluent containing the cleidion brevipetiolatum glycoside A, combining, reducing pressure, concentrating, obtaining cleidion brevipetiolatum glycoside A coarse crystalline particles, separating through a reverse phase silica gel C-18 column preparation efficient liquid phrase method, detecting every part of the eluent through analytical type high performance liquid chromatography, combining cleidion brevipetiolatum glycoside A compositions which are identical in reserved time and have a purity of 90-98% or more than 98% in weight , reducing pressure and concentrating to obtain the cleidion brevipetiolatum glycoside A with the purity of 90%-98% in weight and the cleidion brevipetiolatum glycoside A compositions with the purity of more than 98%, and controlling quality through the thin-layer chromatography and the liquid phrase chromatography.

The invention relates to a traditional Chinese medicinal composition for treating lumbar and cervical bone hyperplasia and a preparation method thereof. The traditional Chinese medicinal composition comprises the following raw materials: galium aparine, euphorbiaceae, diversecolor cinquefoil, chengkou mahonia, azedarach, monkshood, radix aconiti kusnezoffii, fistular onion stalk, ardisia punctata, alangium platanifolium, periploca forrestii schltr, parabarium huaitingii, faamh gov buerng, camphor and alcohol. The invention further provides the preparation method for the traditional Chinese medicinal composition. The traditional Chinese medicinal composition provided by the invention has the effects of dispelling wind, eliminating dampness, warming and activating meridian, activating blood and relieving pain, and has a remarkable effect on treating lumbar and cervical bone hyperplasia.

The invention discloses a medicine for improving microcirculation of a human body. The medicine is characterized by being prepared from the following raw materials in parts by weight: 10g of hedyotis hedyotidea, 2g of golden chrysanthemum, 2g of senecio scandens, 2g of golden cypress, 2g of anemarrhena asphodeloides, 2g of angelica dahurica, 2g of adenophora stricta, 2g of ophiopogon japonicas, 2g of polyporus, 2g of white snakes, 2g of liquorice, 6g of hypericum japonicum, 10g of festuca pratensis, 15g of achyranthes bidentata, 8g of smallcentipedaherb, 15g of parabarium micranthum, 8g of radix Linderae, 8g of euphorbiaceae, 6g of fortunella hindsii, 6g of hyptis suaveolens, 8g of inula cappa, 10g of herba artemisiae anomalae, 10g of ventilago leiocarpa, 20g of suberect spatholobus stem, 5g of zanthor Mu lum nitidum and 15g of millettia dielsiana. According to the prescription of the medicine, multiple traditional Chinese medicines are combined to use, effects of the traditional Chinese medicine components can be improved to the maximum extent, complementary and improvement functions can be brought into play, microcirculation of the human body is greatly improved, the treatment on multiple chronic diseases can be facilitated, medicine options can be enriched for patients, advantages of traditional Chinese medicines can be taken, and thus the medicine has wide market prospects.

The invention discloses a Chinese herbal medicine hot spring milky wash effectively removing facial disease and whitening skin, which is prepared by the following compositions according to balance weight ratio: euphorbiaceae 98 to 108 g; Euphobia thymifolia L 88 to 78 g; helicteres angustifolia 100 to 120 g; cortex dictamni radicis 80 to 100 g; rhiizoma dioscoreae 98 to 108 g; bletilla 78 to 68 g; resveratrol pulp extracted from plygonum cuspidatum38 to 48 g. The Chinese herbal medicine hot spring milky wash has the advantages of not only treating each skin disease such as acne and chromophytosis, caring skin and maintaining the skin and whitening the skin due to using nature pure Chinese herbal medicine with above efficacy, but also preventing each skin disease through skin absorption due to long term use and nourishing and soothing the nerves upon human body.

The invention relates to a method for separating C-type lignin and G / S-type lignin from Euphorbiaceae plant seed coats, and the method comprises the following steps: crushing the Euphorbiaceae plant seed coats, performing heating, centrifuging and concentrating in an inert atmosphere by using an alcohol solvent and / or an oxygen heterocyclic ring solvent under a dilute acid condition to obtain a concentrated solution, adding the concentrated solution into an acidic aqueous solution, performing centrifuging and drying, and finally obtaining the lignin with high C-type content. According to the method, the C-type lignin and the G / S-type lignin are simply and efficiently separated from the Euphorbiaceae seed coats (jatropha curcas, swallow chestnut, tung oil tree and castor-oil plant) which are relatively cheap and wide in source, and the method has excellent yield and higher C-type lignin content. The separated C-type lignin biopolymer provides a single catechol derivative product through palladium-carbon catalytic hydrogenolysis, and possibility is provided for producing catechol compounds from green carbon raw materials.

The invention discloses application of some traditional Chinese medicine extracts in HIV latency reactivation therapy, and belongs to the field of medicine. The application comprises the following steps: grinding Chinese herbal materials; soaking the Chinese herbal powder in an extracting agent for a whole night, wherein a mixture of ethanol or ethyl ether and water is taken as the extracting agent and the volume ratio of the ethanol or ethyl ether to water is at (60-100%) to (40-0%); and extracting the medicines by percolating at low speed, concentrating extracts and removing an extracting solvent, wherein the Chinese herbal materials include one or more of blackberry lily of iridaceae, lowdaphne stringbush flower and leaf, wikstroemia indica, flos genkwa and crown of thorns of thymelaeaceae as well as sapium discolor and euphorbia helioscopia of euphorbiaceae. The traditional Chinese medicine extracts can be applied to preparing medicines for anti-HIV latency therapy.

The invention relates to a separation and purification method for ingenol monomers, and belongs to the technical field of the separation and purification for the active ingredients of traditional Chinese medicines. The separation and purification method disclosed by the invention comprises the following steps: by taking the traditional Chinese medicine moleplant seeds of euphorbia as raw materials, performing ethanol solution extraction, ethyl acetate extraction, silica-gel column chromatography, methanol dissolution and filtration, preparative high-performance liquid chromatographic separation and product recovery to obtain ingenol monomer products. According to the separation and purification method disclosed by the invention, the content of ingenol in the products achieves more than 98% by virtue of the optimum process and parameter conditions; the whole technical process is stable, simple and convenient to operate, high in separation efficiency, and low in cost, and is capable of separating and preparing the ingenol monomers with a high purity.

The invention discloses a synthesis method of Euphorbiaceae diterpene Peplanol A. The synthesis method belongs to the field of organic synthesis, and comprises the following steps: by taking a cycloheptenone derivative 2 as a reaction raw material, constructing a key tricyclic skeleton through key steps of Negishi coupling reaction, Diels-Alder reaction, series cyclization reaction catalyzed by titanium free radicals and the like; finally, the target product Euphorbiaceae diterpene Pepluanol A is obtained through later functional group conversion. The synthesis method disclosed by the invention is simple and convenient to operate, the product is synthesized by 17 steps, the condition is mild, and the total yield reaches 2.5% by controlling the reaction condition. The synthesis route is novel in design thought, the raw materials are cheap and easy to obtain, the compatibility of each important functional group is strong, a plurality of Euphorbiaceae diterpene structure derivatives containing the same 5 / 6 / 7 fused ring skeleton can be conveniently synthesized, and a foundation is laid for the structure-function relationship research of the compounds.

The invention relates to a traditional Chinese medicine composition for treating psoriasis due to stagnated heat of liver channel and relates to the field of traditional Chinese medicines. The composition is prepared from the following raw materials in parts by weight: 13-17 parts of evodia lepta, 10-14 parts of ilex latifolia thumb, 18-22 parts of hedyotis hedyotidea, 8-12 parts of siberian cocklour fruit, 18-22 parts of euphorbiaceae, 10-14 parts of folium murrayae euchrestifoliae, 6-10 parts of common camptotheca fruit, 13-17 parts of waterlettuce herb, 10-14 parts of semi-pinnated brake herb, 10-14 parts of polygonum multiflorum, 4-8 parts of juncus roemerianus and 13-17 parts of fructus cannabis. The traditional Chinese medicine composition is a modern preparation which has the effects of soothing liver and clearing heat, tranquilizing and relieving itching, is used for treating psoriasis due to stagnated heat of liver channel, has the advantages of exact curative effect, stable preparation, controllable quality and no toxic or side effect, and can be easily applied widely.

The invention discloses a tissue culture rapid propagation method for plukenetia volubilis L., also known as plukenetia volubilis, inca inchi, inca peanut and the like, is a perennial woody vine oil plant of the euphorbiaceae, and is native to the tropical rainforest of the Andes mountain area of South America. Vegetable oil squeezed from plukenetia volubilis L. seeds is regarded as the best vegetable oil in the world, and can be used for the aspects of food, health, pharmacy, cosmetics and the like. At present, the plukenetia volubilis L. seedlings are mainly cultivated through seed and cutting manner, and the problems of long period, high cost, low efficiency and the like exist, so that plukenetia volubilis L. in-vitro replantation plant is successfully obtained by taking the plukenetia volubilis L. section stem as an explant through processes of adventitious bud induction, multiplication, rootage, acclimatization, transplantation and the like, a plukenetia volubilis L. tissue culture rapid propagation technical system is established, and important significance is achieved for rapid propagation and large-area popularization of a good variety of the plukenetia volubilis L., as well as promotion of plukenetia volubilis L. industrial development.

The invention belongs to the technical field of pesticides and discloses a mixed herbicide containing pyroxsulam, fluroxypyr and florasulam. The mixed herbicide takes pyroxsulam, fluroxypyr and florasulam as main effective components and the mass ratio of pyroxsulam to fluroxypyr to florasulam is (1-80) to (1-40) to (1-60). The mixed herbicide can be applied to prevention and removal of weeds in oilseed rape fields. According to the mixed herbicide provided by the invention, the weeding spectrum is enlarged by the mixing of the herbicide and the weeding effect is improved; and the herbicide has the advantages of rapid effect, long lasting period, delaying of herbicide drug resistance, complete weeding, low residues, low toxin, safety and environment friendliness and the like; and the herbicide is a high-quality chemical herbicide of the oilseed rape fields, is safe to oilseed rapes, and has prominent prevention and treatment effects on grassy weeds, euphorbiaceae weeds, caryophyllaceae weeds, and rubiaceae weeds, such as oat, alopecurus aequalis, barnyard grass, euphorbia helioscopia, leptochloa chinensis, galium aparine, stellaria media and malachium aquaticum.

The present invention relates to the field of the production of transgenic plants through Agrobacterium-mediated transformation of cells of somatic embryogenic calli or embryogenic suspension cultures and regeneration of the transformed cells into fruit-setting plants. In particular, the present invention relates to the production of transgenic plants in the Euphorbiaceae family. The present invention further relates to media compositions, selection methods and engineered Agrobacterium tumefaciens strains that improve Agrobacterium-mediated transformation efficiency.

The present invention relates to the use of a plant material of the species Trichilia sp., alone or in association with one or more of the following plants: Paullinia cupana (Sapindaceae), Croton moritibensis (Euphorbiaceae) and Zingiber officinale (Zingiberaceae) in the treatment, reversion, combat and / or prevention of ventricular fibrillation. A product particularly embraced by the present invention comprises the plant material of the species Trichilia sp., alone or in association with extracts from other plants. The invention also refers to the use of one or more fractions of plant extract from such plant material, particularly of Trichilia catigua A. Juss, and of one or more subfractions of said fractions in the treatment, combat, prevention and / or reversion of ventricular fibrillation.

The invention discloses a method for inducing plukenetia volubilis to bloom. Plukenetia volubilis is a perennial wood vine oil plant of Euphorbiaceae, and plukenetia volubilis oil squeezed from seeds of the plukenetia volubilis is rich in polyunsaturated fatty acids such as alpha-linolenic acid, alpha-linoleic acid and oleic acid and has wide application prospects in the fields of food, medicines, cosmetics and the like. However, plukenetia volubilis planted in the southeast region of Guangxi Guangxi cannot bloom normally. According to the method, a gibberellin rare earth complex is synthesized and prepared into a 10-20 [mu] mol / L solution, the solution is sprayed to the whole plukenetia volubilis from the initial flowering stage to the young fruit development stage, the spraying amount is appropriate when liquid drops appear on leaf surfaces, and the solution is sprayed once every 10 days. According to the method provided by the invention, plukenetia volubilis plants can be induced to bloom, each branch generates 5-8 inflorescences with multiple female flowers, and each inflorescence has 5-10 female flowers. The method is simple and convenient to operate, low in cost and remarkable in flower promoting effect, can remarkably promote flowering of plukenetia volubilis, and has a good application prospect.

Taking leaves of cleidion brevipetiolatum of Cleidion of Euphorbiaceae as raw material, the invention provides a preparation method, a detecting method and use of high purity cleidion brevipetiolatum glycoside A. The preparation method includes the steps of smashing leaves of the cleidion brevipetiolatum of the Euphorbiaceae, heating though alcohol for reflux extraction, achieving chromatography for ethanol extract through a silicagel column, eluting through chloroform-carbinol mixed solvent, detecting through thin-layer chromatography, collecting eluent containing the cleidion brevipetiolatum glycoside A, combining, reducing pressure, concentrating, obtaining cleidion brevipetiolatum glycoside A coarse crystalline particles, separating through a reverse phase silica gel C-18 column preparation efficient liquid phrase method, detecting every part of the eluent through analytical type high performance liquid chromatography, combining cleidion brevipetiolatum glycoside A compositions which are identical in reserved time and have a purity of 90-98% or more than 98% in weight , reducing pressure and concentrating to obtain the cleidion brevipetiolatum glycoside A with the purity of 90%-98% in weight and the cleidion brevipetiolatum glycoside A compositions with the purity of more than 98%, and controlling quality through the thin-layer chromatography and the liquid phrase chromatography.

The present invention relates to an euphorbiaceae plant active substance for restraining growth of cancer and / or tumor and application thereof. The euphorbiaceae plant active substance is extracted from the euphorbiaceae plant by alcohol and furthermore can be extracted by n-hexane. The invention further relates to use of the euphorbiaceae plant active substance in preparing a composition for restraining growth of the cancer and / or tumor cell.

The invention provides a plant-sourced pesticide for preventing wheat powdery mildew and a preparation method and application thereof. The pesticide comprises Euphorbiaceae plant extract, a solubilizer and water, wherein the weight percent of each component is as follows: 15 to 45 percent of the Euphorbiaceae plant extract, 1 to 20 percent of solubilizer, and the balance of water; and the Euphorbiaceae plant extract is prepared by drying one of or a mixture of branches, stems, leaves, flowers and fruits of an Euphorbiaceae plant, grinding the mixture into powder, and extracting the mixture powder by adopting an organic solvent as an extraction solvent and by adopting a decompression concentration method. The plant-sourced pesticide has relatively high control effect for the wheat powdery mildew, can be directly used for preventing the wheat powdery mildew, and has characteristics of nuisancelessness, no pollution and no residue and can avoid the harm of chemical pesticides.

The invention discloses application of some traditional Chinese medicine extracts in HIV latency reactivation therapy, and belongs to the field of medicine. The application comprises the following steps: grinding Chinese herbal materials; soaking the Chinese herbal powder in an extracting agent for a whole night, wherein a mixture of ethanol or ethyl ether and water is taken as the extracting agent and the volume ratio of the ethanol or ethyl ether to water is at (60-100%) to (40-0%); and extracting the medicines by percolating at low speed, concentrating extracts and removing an extracting solvent, wherein the Chinese herbal materials include one or more of blackberry lily of iridaceae, lowdaphne stringbush flower and leaf, wikstroemia indica, flos genkwa and crown of thorns of thymelaeaceae as well as sapium discolor and euphorbia helioscopia of euphorbiaceae. The traditional Chinese medicine extracts can be applied to preparing medicines for anti-HIV latency therapy.

The invention belongs to the technical field of natural polymers, and particularly relates to a 2-quinolinone-citrinin hybrid dimer compound as well as a preparation method and application thereof. One monomer 4-hydroxy-1-methyl quinoline-2-ketone alkaloid in the 2-quinolinone-citrinin hybrid dimer compound disclosed by the invention is mainly obtained from actinomycetes Dactylosporangium sp. Of plants such as rutaceae and euphorbiaceae at present, and actinomycetes Dactylosporangium sp. Of soil sources are mainly obtained from actinomycetes Dactylosporangium sp. Of plants such as the rutaceae and the euphorbiaceae at present. The compound has wide biological activity, such as anti-platelet aggregation, chymotrypsin inhibition, anti-tumor activity, antibacterial activity, anti-tuberculosis activity and the like. The method can be applied to the field of antibacterial drug preparation.