The invention discloses anti-oxidant lubricating grease, belonging to the technical field of lubricants. The technical scheme of the invention is that the anti-oxidant lubricating grease is prepared from the following raw materials in parts by weight: 10-30 parts of an oligomer of trimethyl dihydroquinazolone, 2-10 parts of isodehydrocostus lactone, 1-6 parts of tetrahydropalmatine, 2-7 parts of sodium dipenta acid, 2-7 parts of bissalicylidene propane diamine, 3-9 parts of p-Hydroxybenzaldehyde, 1-3 parts of methyl citrate, 2-7 parts of chlorinated paraffin, 2-10 parts of diphosphorothioate, 1-3 parts of monoglvceride citrate, 2-5 parts of alkyl succinimide, 1-3 parts of viburnum themoidigenic acid, 1-5 parts of boron nitride, 1-3 parts of oleanonic acid, 2-8 parts of lupeol palmitate and 2-5 parts of polyisobutene. Compared with the prior art, the anti-oxidant lubricating grease disclosed by the invention is simple to prepare, economical and practical and low in cost, can effectively prevent instruments from being damaged, and is high in anti-oxidant performance, long in service cycle, free from any damages to mechanical equipment, and meanwhile has good frictional characteristic, wear resistance and anti-corrosion performance.