Separation and purification method for ingenol monomers

A technology for the separation and purification of ingenol, which is applied in the field of separation and purification of ingenol monomers and the preparation of plant compound monomers, can solve the problems of no production and extraction process, and achieve product quality, product quality control, and energy saving The effect of production costs
CN103694096BActive Publication Date: 2015-04-08CHENGDU PUSH BIOLOGICAL TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
CHENGDU PUSH BIOLOGICAL TECH
Publication Date
2015-04-08

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Abstract

The invention relates to a separation and purification method for ingenol monomers, and belongs to the technical field of the separation and purification for the active ingredients of traditional Chinese medicines. The separation and purification method disclosed by the invention comprises the following steps: by taking the traditional Chinese medicine moleplant seeds of euphorbia as raw materials, performing ethanol solution extraction, ethyl acetate extraction, silica-gel column chromatography, methanol dissolution and filtration, preparative high-performance liquid chromatographic separation and product recovery to obtain ingenol monomer products. According to the separation and purification method disclosed by the invention, the content of ingenol in the products achieves more than 98% by virtue of the optimum process and parameter conditions; the whole technical process is stable, simple and convenient to operate, high in separation efficiency, and low in cost, and is capable of separating and preparing the ingenol monomers with a high purity.
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Description

technical field

[0001] The invention relates to a preparation method of a plant compound monomer, in particular to a separation and purification method for extracting ingenol monomer from Stephania chinensis, belonging to the technical field of separation and purification of traditional Chinese medicines. Background technique

[0002] Qianjinzi is the seed of Euphorbialathyris L., a plant of Euphorbiaceae. Also known as Qianliang Gold, Bodhisattva Dou ("Rihuazi"), Xu Suizi ("Kaibao Materia Medica"), Judongshi ("Bencao Tujing"), Lianbu ("Doumen Fang"), Judongzi ( "Compendium of Materia Medica"), Tanbanjiu ("Hunan Drug Records"), Kanyuanlao ("Guizhou Herbal Medicine"), Baiyaojie, Ganjinyaojie ("Yunnan Medicinal Plants"), Xiaocrodou ("Guizhou Herbal Medicine") Shanxi Chinese Herbal Medicine"). The original plant Suizi is also known as: Resisting Winter ("Kaibao Materia Medica"), Banzhilian ("Compendium Supplements"), Jianglongcao ("Shaanxi Traditional Chinese Medicine List")....

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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