744results about How to "Increase concentration" patented technology

The invention discloses a method for in vitro slow release performance evaluation of a slow and controlled release preparation based on the overflow principle. A container with an upper outlet and a lower outlet is adopted to serve as a release tank, a to-be-detected medicine and a dissolution medium are placed in the release tank, a stirring device is adopted in the release tank to perform stirring, and the dissolution medium is added from the lower outlet of the release tank through a peristaltic pump; the dissolution medium dissolved with the medicine is taken away through the overflow from the upper outlet so as to offset medicine absorption or metabolism, and the slow and controlled release speed of the medicine, the total medicine overflow quantity and the total release amount are calculated by measuring the concentration of the medicine contained in the dissolution medium flowing out, the volume of the release tank and the overflow quantity. According to the method, the releasing degree of the slow and controlled release medicine can be evaluated accurately, the effective medicine release time of the slow and controlled release preparation is evaluated, and slow release performances of the slow and controlled release preparation are evaluated comprehensively.

The present application provides a method for diagnosing and / or evaluating the presence or absence, severity or degree of the improvement of a retinal disease in a subject, which comprises determining and / or evaluating circulatory parameters, retinal function, retina morphology and / or visual relating quality of life (QOL).

The invention relates to an engineering bacterium of high-yield ornamental blue as well as a construction method and application of the engineering bacterium, and belongs to the technical field of natural dye synthesis by a biological method. The engineering bacterium capable of highly producing the ornamental blue, disclosed by the invention, expresses icd, bpsA, glnAY405F and gd hA; acnR, yggB, glsK, aceA and ldh are knocked out from the engineering bacteria. According to the application, yggB and aceA genes are knocked out, site-directed mutagenesis (Y405F) is carried out on a glnA gene, a glsK gene is replaced by a glnAY405F gene, an acnR gene is replaced by an icd gene, an ldh gene is replaced by a gdhA gene, and a bpsA gene is integrated, so that the formation of by-products such as lactate and succinic acid in a blue-viewing synthesis process can be blocked; the flow direction of a passage from citric acid to isocitric acid to alpha-ketoglutaric acid to glutamic acid to glutamine is improved, so that the concentration of glutamine in cells is improved, and the yield of the ornamental blue is improved.

The invention belongs to the technical field of wastewater treatment, and particularly relates to an efficient ozone micro-nano bubble preparation system and a process method thereof. The device further comprises an ozone preparing unit, a gas conveying pipeline, a jet flow unit, a spiral mixing unit, a Venturi tube, a microporous membrane unit and a reaction unit. The ozone producing unit is connected with the jet flow unit through a gas conveying pipeline, the ozone producing unit comprises an ozone generator, and the gas inlet pressure is regulated and controlled through a gas valve in the gas conveying pipeline; and the jet flow unit is used for generating and conveying a mixed solution with ozone microbubbles. The jet flow unit enables the mixed liquid to form ozone microbubbles based on a Venturi effect and a hydraulic shearing effect; by arranging the jet flow unit, the spiral mixing unit, the Venturi tube and the microporous membrane unit, ozone micro-nano bubbles with high concentration and uniform size distribution can be generated under relatively low energy consumption, so that the treatment efficiency of the ozone micro-nano bubbles in the technical fields of wastewater treatment and environmental protection is improved.

The invention discloses a method for directly repairing and regenerating a ternary positive electrode recycled material. The method comprises the following steps: S1, disassembling a ternary retired battery; s2, sintering to remove impurities; s3, removing powder and sieving; s4, mixing with crystalline lithium salt; s5, crushing and sieving after sintering and cooling; s6, mixing with a metal oxide; and S7, sintering, cooling, removing iron, and sieving. The eutectic lithium salt is used as a lithium source for lithium supplement, so that the diffusion rate of lithium ions can be increased, the concentration of the lithium ions can be improved, the reaction temperature of lithium supplement recovery can be reduced, and the energy consumption can be reduced. The ternary lithium battery is wrapped by the metal oxide, residual lithium on the surface of the material can be utilized, a layer of fast ion conductor can be formed on the surface of the material in situ, and the residual lithium on the washed surface is removed, so that the process is shortened, the cost is reduced, the transmission rate of lithium ions can be further improved, and the rate capability of the battery is improved. And the fast ion conductor structure can isolate the contact between the electrolyte and the positive electrode material, so that side reaction is reduced, and the cycle performance is improved.

The invention discloses a sewage sludge advanced treatment device, which belongs to the technical field of sludge treatment, and comprises a flocculation basin and a dehydration device, a concentration adjusting tank is arranged between the flocculation basin and the dehydration device, the inside of the tank is divided into a high-concentration area and a low-concentration area through a filter plate, the high-concentration area is provided with a first liquid inlet pipe, and the low-concentration area is provided with a second liquid inlet pipe; flowing into a dehydration device through a mixing pump; the filter plate is controlled by a driving mechanism to move so as to change the volume of the high-concentration area, and a first concentration detector is mounted on the first liquid inlet pipe and is used for moving the filter plate to reduce the volume of the high-concentration area when the first concentration detector detects that the concentration is lower than a threshold value; a control valve is installed on the second liquid inlet pipe and used for opening the control valve when the first concentration detector detects that the concentration is larger than the threshold value. The concentration regulating tank is arranged between the flocculation tank and the dehydration device to regulate the concentration of the sludge, so that the concentration of the sludge input into the dehydration device is stable, and the qualified rate of sludge caking is ensured.

The invention discloses a multi-metal borate nano-particle as well as a preparation method and application thereof. The preparation method comprises the following steps: in the presence of small molecules with alkyl chains, performing high-temperature thermal decomposition on an organic metal compound or a metal salt compound precursor and organic borate in a solvent, and then centrifuging, modifying, performing ultrafiltration, dialyzing and purifying to obtain the multi-metal borate nanoparticles. The preparation method disclosed by the invention has the characteristics of mildness, high efficiency and strong controllability. The multi-metal borate nanoparticles prepared by the preparation method disclosed by the invention have the advantages of monodisperse size, relatively high magnetic property and good biocompatibility. Therefore, the prepared multi-metal borate nanoparticles not only have multi-modal imaging functions such as magnetic resonance imaging, near-infrared two-region imaging, nuclear medicine imaging and magnetic particle imaging, but also can be used for various treatment means such as magnetocaloric therapy and boron neutron capture therapy; potential advantages are realized in biomedical applications such as magnetic targeting tumor treatment and imaging contrast agents, and high practical values are realized.

The invention relates to the technical field of seawater desalination, in particular to a seawater desalination reverse osmosis membrane, a preparation method and application. The seawater desalination reverse osmosis membrane is prepared by the preparation method. The preparation method comprises the following steps: immersing the prepared support layer into a water phase solution, and then taking out the support layer adsorbing the water phase solution; immersing the support layer adsorbing the water phase solution into a first oil phase solution, and forming a primary reverse osmosis membrane through a first interfacial polymerization reaction; then, taking out the primary reverse osmosis membrane, and carrying out first drying treatment under a steam condition; and immersing the primary reverse osmosis membrane into a second oil phase solution, and carrying out a second interfacial polymerization reaction to form the seawater desalination reverse osmosis membrane. The application refers to the application of the reverse osmosis membrane for seawater desalination in the aspects of reclaimed water reuse, seawater desalination and brackish water desalination. According to the invention, the seawater desalination reverse osmosis membrane which simultaneously meets high desalination rate and high water flux can be prepared.

The invention discloses a process for treating rural domestic sewage by using an improved A2 / O + MBBR (Moving Bed Biofilm Reactor), and relates to the technical field of sewage treatment. The method comprises the steps of S1, initial-stage treatment, S2, reflux treatment and S3, tail-stage treatment. The rural domestic sewage is treated by an improved A2 / O + MBBR nitrogen and phosphorus removal process, and the rural domestic sewage is distributed into each tank by adopting a sectional water inlet technology, so that an alternate multi-stage facultative / aerobic environment is formed, and the biological nitrogen and phosphorus removal effect is enhanced; the improved A2 / O + MBBR process has the advantages of high nitrogen and phosphorus removal effect, low investment and operation cost, convenience in operation and management and the like; all returned sludge enters the pre-denitration tank and enters the front-section anaerobic tank and the front-section anoxic tank, a sludge concentration gradient from high to low is formed in each tank, and the average sludge concentration in each tank is increased and the hydraulic load of the sedimentation tank is not changed under the condition that the effluent sludge concentration is not increased, so that the proliferation speed of phosphorus-accumulating bacteria and nitrifying bacteria is accelerated; the proportion in the total amount of the activated sludge is increased, so that the nitrogen and phosphorus removal effect is improved.

The invention discloses a bipolar membrane and a preparation and use method thereof, the bipolar membrane comprises a cation exchange membrane, the cation exchange membrane comprises a base material and a cation exchange layer arranged on at least one surface of the base material, and sulfonic acid type ionic liquid is added in the cation exchange layer; the metal catalyst layer is arranged on one surface of the base material, so that the cation exchange layer and the metal catalyst layer are respectively arranged on two opposite surfaces of the base material; the anion exchange layer is arranged on the surface of the metal catalyst layer and comprises quaternized imidazole derivatives and quaternary ammonium type ionic liquid, and the quaternary ammonium type ionic liquid accounts for 25% or above of the weight of the imidazole derivatives. The method has the advantages of high acid and alkali production concentration, stable membrane structure, stable performance and the like, and is suitable for long-term and stable preparation of high-concentration acid and alkali.

The invention relates to mussel mucin-hyaluronic acid nanogel and a preparation method and application thereof and a pharmaceutical composition, and belongs to the field of biomedical materials, the structural formula of the mussel mucin-hyaluronic acid nanogel is # imgabs0 #, Mussel mucin is a mussel mucin molecule, and n is the number of repetitive units. The mussel mucin-hyaluronic acid nanogel can be swelled in a water-based medium to form a three-dimensional space net-shaped structure, pharmaceutical active molecules are better entrapped, lysine and dopa groups in the structure can be tightly combined with the surface or mucous membrane of an organism through electrostatic interaction, hydrogen-bond interaction and oxidative crosslinking, so that the bioavailability of the mussel mucin-hyaluronic acid nanogel is improved, and the bioavailability of the mussel mucin-hyaluronic acid nanogel is improved. The carrier has good biological adhesion, can prolong the residence time of the carrier on an organism or mucous membrane surface, and promotes drug absorption. The mussel mucin-hyaluronic acid nanogel can also be used as a drug storage cavern, so that the slow release effect of drugs is improved, the action time of the drugs is prolonged, and the administration frequency is reduced.

The present invention discloses a distributed water mixing heating device, which specifically relates to the technical field of water mixing heating, including a heating pipe, a filter assembly 1 is fixedly connected to the rear end of the heating pipe, two symmetrically arranged filter assemblies 2 are fixedly connected to the rear end of the filter assembly 1, and the ends of the two filter assemblies 2 close to each other are fixedly connected to a water mixing assembly, a heating assembly is fixedly connected to the right side of the rear end of the water mixing assembly, and a storage assembly is fixedly connected to the left side of the heating assembly. A distributed water mixing heating device of the present invention can drive a toggle rod to rotate through a transmission belt when an impeller is impacted by a water flow, so that the corrosion and scale inhibitor can be added in an appropriate amount according to the water output, thereby ensuring that the corrosion and scale inhibitor reaches an optimal concentration in the circulating water, thereby avoiding the formation of metal corrosion residues and scale in the inner cavity of the heating pipe when the metal equipment is used for too long, and further extending the service life of the equipment.

The invention discloses a Gegen Qinlian decoction vesicle-like nanoparticle as well as an extraction method and application thereof, and belongs to the technical field of biological medicines. The method comprises the following steps: preparing a radix puerariae qinlian decoction stock solution; placing at 4-8 DEG C for 12-15 hours to obtain a gelatinous substance; carrying out low-speed centrifugation at 4-8 DEG C, and taking supernate, so as to obtain crude extract of the vesicle-like nanoparticles of the radix puerariae, radix scutellariae and rhizoma coptidis decoction; carrying out ultracentrifugation at 4-8 DEG C, discarding the supernatant, and carrying out PBS resuspension precipitation to obtain a crude product of the vesicle-like nano-particles of the Gegen Qinlian decoction; and centrifuging 16000g at the temperature of 4-8 DEG C for 10-15 minutes, taking supernate, and filtering by using a 0.22 mu m filter membrane, so as to obtain the vesicle-like nanoparticles of the Gegen Qinlian decoction. According to the Gegen Qinlian decoction vesicle-like nanoparticles as well as the extraction method and the application thereof, the bioavailability and the targeting property of effective components in the Gegen Qinlian decoction are remarkably improved through a nanocrystallization technology, the concentration of the medicine at the ulcerative colitis part is enhanced, and the treatment effect is effectively improved.

The invention provides an anaerobic gas-feeding bacterium subjected to mutagenesis screening and application of the anaerobic gas-feeding bacterium in high-yield acid production through synthesis gas conversion. The anaerobic gas-feeding bacterium is a Clostridium sp. Strain P38 strain, and the preservation number of the anaerobic gas-feeding bacterium is CGMCC (China General Microbiological Culture Collection Center) No.46262. According to the invention, an acid-producing Clostridium sp. Strain P38 strain is obtained through ARTP mutagenesis screening, and through optimization of culture conditions, especially addition of sodium molybdate in a culture system and control of the pH value of the culture system, the maximum concentration of bacteria fermented by the anaerobic gas-feeding bacteria Clostridium sp. Strain P38 and the capability of fermentation acid production are improved, the maximum cell concentration of the strain can reach OD600nm-2. 0Abs, the maximum acetic acid yield is 5g / L, and the hexanoic acid content is 3.5 g / L.

The invention provides an air conditioner which comprises a machine shell, a first refrigerant detection area is arranged in the machine shell, a second refrigerant detection area is arranged outside the machine shell, and the first refrigerant detection area communicates with the second refrigerant detection area; the indoor heat exchanger is arranged in the machine shell, and an input port and an output port of the indoor heat exchanger are located in the first refrigerant detection area; the refrigerant input pipe and the refrigerant output pipe are connected with an input port and an output port of the indoor heat exchanger respectively, and the ends, away from the indoor heat exchanger, of the refrigerant input pipe and the refrigerant output pipe are provided with piping joints; the tubing connector penetrates through the machine shell and is arranged to be connected with an indoor and outdoor unit connecting pipe located outside the machine shell, and the connecting portion of the tubing connector and the indoor and outdoor unit connecting pipe is located in the second refrigerant detection area; and the refrigerant detection sensors are arranged in the first refrigerant detection area and / or the second refrigerant detection area. According to the scheme, refrigerant leakage can be detected in time, so that flammable and explosive risks caused by refrigerant leakage are reduced.

The invention belongs to the technical field of microbial fermentation, and particularly relates to a fermentation substrate for bacillus, a bacillus liquid fermentation inoculant and application. The fermentation substrate is prepared by adding traditional Chinese medicine residues into a yeast culture medium so as to improve the concentration of bacillus after fermentation; the traditional Chinese medicine residues are prepared by compounding motherwort herb residues, astragalus membranaceus herb residues and ginseng herb residues according to the mass ratio of 1: (1-2): (1-1.5); the mass ratio of the yeast culture medium to the traditional Chinese medicine residues is (20-26): (6-8). The concentration of the bacillus can reach 3.3 * 10 < 9 > CFU / mL in a bacillus liquid fermentation inoculant obtained by adopting the fermentation substrate disclosed by the invention.

The invention belongs to the technical field of polycarbosilane, and particularly relates to a synthesis method of polydimethylsilane and application of the polydimethylsilane in preparation of polycarbosilane. In the Wurtz polymerization reaction of polydimethylsilane, polar solvents such as crown ether, diethylene glycol dimethyl ether, hexamethylphosphoric triamide and polyether are added into a reaction system, and the polar solvents have a complexing effect on sodium ions, so that tight ion pairs can be promoted to become loose ion pairs, the concentration of active anions is greatly increased, and the reaction time is shortened; therefore, the initiation period of the reaction is shortened, the polymerization reaction speed is accelerated, the molecular weight of polydimethylsilane is improved, and the yield is improved; the molecular weight of the polydimethylsilane is increased, the pyrolysis activation energy of the polydimethylsilane is gradually reduced, and the prepared polycarbosilane has higher Si-H bonds, and is high in A-grade conversion rate and good in spinning performance; according to the method, original reaction equipment does not need to be changed, reaction process parameters are also in original design, and the method has practical application value.

The invention discloses high-purity oxamide with concentrated particle size and spherical morphology, a preparation method of the high-purity oxamide and application of the high-purity oxamide in preparation of a slow-release fertilizer, and belongs to the technical field of oxamide synthesis and application. The method comprises the following steps: mixing an ammonia-alcohol solution and an alcohol ester solution, conveying the mixed solution into a series tubular reactor for reaction, and then conveying the mixed solution into a parallel tubular reactor for reaction after pressure stabilization and flow equalization to obtain a reaction solution containing oxamide; performing flash evaporation on the reaction liquid to obtain flash evaporation liquid and flash evaporation gas, and performing solid-liquid separation on the flash evaporation liquid to obtain solid oxamide and filtrate; and drying the solid oxamide to obtain the oxamide. The method realizes high conversion rate and high purity, and the product has ultrafine particle size distribution. The purity of the prepared oxamide is greater than or equal to 99%, the D50 particle size is concentrated to 50 + / -15 microns, the spherical morphology is uniform, the release is stable, and the oxamide has a very good effect in preparation of long-acting slow-release fertilizers and combustion inhibitors and research on the nitrogen utilization rate.

The invention discloses a high-entropy multiple silicon-carbon functional material and a preparation method thereof, a negative pole piece and a lithium ion battery. The high-entropy multiple silicon-carbon functional material is a composite negative pole material formed by compounding an oxygen-enriched high-entropy oxide, multiple carbon gel and nano silicon; in the high-entropy multiple silicon carbon functional material, the high-entropy oxide material is coated with multiple carbon gel to form a composite material, and the composite material is also loaded with nano silicon particles. The high-entropy multi-silicon-carbon functional material is applied to manufacturing of the lithium ion battery, and the high-entropy material has a specific multi-element synergistic effect, a large number of active sites and structural stability, so that the silicon-carbon negative electrode is further optimized, and the energy density and the electrochemical performance of a battery cell in the lithium ion battery can be obviously improved.

The invention belongs to the technical field of electrolytic copper foils, and relates to an additive for an ultralow-profile electrolytic copper foil, an electrolyte, a preparation process of the electrolytic copper foil, the electrolytic copper foil and application of the electrolytic copper foil. The additive comprises a brightening agent, a wetting agent and a leveling agent; the brightening agent is hexylbenzylamine salt, sodium dithiodipropane sulfonate and sodium N, N-dimethyl dithioformamide propane sulfonate; the wetting agent is hydroxyethyl cellulose and polyethylene glycol; and the leveling agent is hydrolyzed collagen. When the electrolyte containing the additive is used for preparing the copper foil, grain refinement of the raw foil and leveling of the outline are realized, and a foundation is laid for realizing the ultralow-outline electrolytic copper foil. And the design of the front section, the middle section and the rear section of the anode plate is combined, an original two-step method is replaced for producing the electrolytic copper foil, equipment is simplified, the production technological process is shortened, and the production cost of the ultra-low-profile electrolytic copper foil is greatly reduced.

The invention belongs to the technical field of semiconductor processing, and discloses semiconductor processing-based etching equipment, which comprises a support box, a processing box and an etching box, a recovery pipe is installed on the left side of the support box, one end of the recovery pipe is communicated with the processing box, the etching box is installed on the top of the support box, and the processing box is communicated with the processing box. And a liquid storage box is installed in an inner cavity of the supporting box and communicates with the treatment box, a pump is installed on the right side of the liquid storage box, and the drainage end of the pump is fixedly connected with a communicating pipe. According to the device, the telescopic rod drives the second sealing plate to contract and move, the recovery opening is opened, and etching waste liquid subjected to consumption reaction is discharged in time, so that the etching liquid in the isolation chamber can be replaced for multiple times, reactant residues on the surface of a wafer can be washed away every time the etching liquid is replaced, the stability of the pH value in the isolation chamber is maintained in time through the design, and the service life of the wafer is prolonged. And the concentration of reactants generated by consumption of the etching liquid in the isolation chamber is reduced, and the reaction rate is increased.

The invention relates to the technical field of lithium ion battery recovery, in particular to an electrochemical recovery method of a retired lithium iron phosphate battery, which comprises the following steps: preparing an electrode and constructing an electrolytic tank; performing an electrochemical leaching lithium extraction reaction and a circulating experiment; lithium precipitation and anode recovery; and regenerating the electrolyte. According to the method, the retired lithium iron phosphate battery electrode material is recycled by adopting an electrochemical selective leaching lithium extraction technology, the recovery rate of lithium can reach 89% or above, the recovery rate of iron phosphate can reach 90% or above, the regeneration rate of an anode side electrolyte and a cathode side electrolyte can reach 95% or above, and the selectivity of lithium leaching can reach 900 or above.

The invention discloses a method for purifying modified sophorolipid, which comprises the following steps: adding a salt solution into lactone type crude sophorolipid obtained by fermenting candida bumblebee, stirring, standing, and collecting a lower layer sophorolipid phase; according to the method, the produced crude sophorolipid with low or high emulsification degree is purified, impurities are removed, good appearance conditions are achieved, and the appearance requirement of the commodity sophorolipid is met. And meanwhile, the sophorolipid is modified in the purification process by utilizing the chemical properties of different salts, so that the decoloration of the sophorolipid is realized, the concentration of the lactone type sophorolipid is improved, and the stability of the lactone type sophorolipid is improved at the same time.

The invention relates to the technical field of cables, in particular to a semiconductive shielding material and a preparation method thereof, oxygen plasma reaction equipment and a cable. The semi-conductive shielding material is prepared from the following components in parts by weight: 55 to 65 parts of vinyl resin matrix, 1.5 to 2 parts of cross-linking agent and 30 to 40 parts of filler, the filler at least comprises modified conductive filler; the modified conductive filler comprises a first oxygen-containing functional group and a second oxygen-containing functional group, the first oxygen-containing functional group comprises one or more of hydroxyl and ether, and the second oxygen-containing functional group comprises one or more of carbonyl, COO-and carboxyl; the modified conductive filler meets the following relational expression: C1 / n1 < = C2 / n2, C1 is the total concentration of the first oxygen-containing functional groups, n1 is the number of functional group types included in the first oxygen-containing functional groups, C2 is the total concentration of the second oxygen-containing functional groups, and n2 is the number of functional group types included in the second oxygen-containing functional groups.

The invention belongs to the technical field of target material production, and discloses a ZMO target material which is prepared from zinc oxide, magnesium oxide and doped metal oxide. Wherein the doped metal oxide is selected from at least one of tantalum pentoxide, cerium dioxide, titanium dioxide, niobium pentoxide, manganese sesquioxide and chromium sesquioxide, the mass ratio of metal elements in zinc oxide to metal elements in magnesium oxide is (73-91): (9-27), and meanwhile, the metal elements in the doped metal oxide account for 1000-10000 ppm of the total mass of the metal elements in the target material. Through the design, on one hand, the relative density of the target material is improved, and on the other hand, higher carrier concentration or more excellent carrier migration capability is provided for the target material by doping the metal oxide, so that the resistivity of the target material is reduced; in addition, the invention also discloses a preparation method of the ZMO target material.

The invention relates to a polymyxin inhalation liquid preparation and a preparation method thereof. The polymyxin inhalation liquid preparation comprises 0.1-5% (W / V) of polymyxin B sulfate, 0.05-1% (W / V) of a stabilizer, 0.1-0.9% (W / V) of an osmotic pressure regulator, a pH value regulator and a solvent, the pH (Potential of Hydrogen) of the liquid preparation is 3.0 to 6.0; the solvent is selected from purified water and water for injection; the polymyxin inhalation solution provided by the invention is simple in composition, the pH value of the polymyxin inhalation solution is 3.0-6.0, osmotic pressure and isotonic pressure are simultaneously realized, bronchus spasm and cough caused by the polymyxin inhalation solution can be reduced, safety evaluation verifies that the polymyxin inhalation solution has better safety, and a new choice is provided for clinical application.

The invention discloses cyclohexene formate esterase, a mutant of cyclohexene formate esterase and application of cyclohexene formate esterase in production of (S)-3-cyclohexene-1-formic acid. According to the cyclohexene formate esterase and the mutant disclosed by the invention, 100-400g / L of racemic 3-cyclohexene-1-methyl formate can be split by taking wet thalli subjected to induced expression or crude enzyme liquid obtained by ultrasonically crushing the wet thalli as a catalyst, so that (S)-3-cyclohexene-1-formic acid with chemical purity and optical purity reaching 99% or above is synthesized. The enzyme activity of the cyclohexene formate esterase mutant provided by the invention is further improved, the reaction time and the catalyst dosage are obviously reduced compared with those of a substrate with the same catalysis concentration before mutation, the reaction condition is mild, the operation is relatively simple and convenient, and the cyclohexene formate esterase mutant has a very good industrial application prospect.

The invention belongs to the technical field of biological medicines, and particularly relates to schisandra chinensis exosome-like vesicles and application thereof in preparation of anti-depression products. The schisandra chinensis exosome-like nano-vesicles are prepared by a method of combining differential centrifugation with ultra-high-speed centrifugation. The prepared exosome-like nano vesicles derived from schisandra chinensis can be taken in by nerve microglial cells, and the inflammatory response induced by LPS is inhibited; meanwhile, the LPS-induced mouse depression-like behavior can be improved, and the pathological injury of the hippocampus can be relieved. The invention establishes the preparation method of the schisandra chinensis exosome-like nano-vesicle, and verifies that the schisandra chinensis exosome-like nano-vesicle has an anti-depression effect, so that the schisandra chinensis exosome-like nano-vesicle has a relatively good development and utilization prospect.

The invention relates to an adhesion modified ionic conductive hydrogel for temperature and humidity sensing, a preparation method thereof and a storage device. The invention discloses adhesion-modified composite cross-linking ionic conductive hydrogel and a preparation method thereof, and relates to the technical field of polymer composite materials. The preparation method comprises the following steps: carrying out in-situ polymerization on polyvinyl alcohol, acrylamide, acrylic acid, cellulose, lithium chloride, a covalent cross-linking agent and an initiator at 50-60 DEG C by a one-pot method for 4-6 hours to obtain a precursor; carrying out low-temperature freeze-thaw cycle at-20 DEG C or below for 2-4 times; and carrying out polyol solvent exchange twice to obtain the polymer. Through in-situ polymerization covalent cross-linking and cellulose grafting, reversible physical cross-linking and secondary solvent exchange steps, the adhesive property of the hydrogel and the durability of the hydrogel in a low-temperature and natural dry environment can be improved on the basis of improving the mechanical property of the hydrogel, and the hydrogel can be used for assembling flexible stress-strain, temperature and humidity sensors and has wide application prospects. The invention also provides an adhesion modified ion conductive hydrogel storage device used for temperature and humidity sensing.

The invention discloses a p-Ga2O3 / n-Ga2O3pn junction diode and a preparation method thereof, and solves the problems that gallium oxide p-type doping is difficult, and a heterojunction diode is large in leakage current and low in withstand voltage. The gallium oxide homogeneous pn junction structure comprises cathode metal, a substrate and an n-type Ga2O3 epitaxial layer from bottom to top, a p-type NiO layer is arranged above the n-type Ga2O3 epitaxial layer, a p-type Ga2O3 material layer is arranged between the n-type Ga2O3 epitaxial layer and the p-type NiO layer, and a gallium oxide homogeneous pn junction is formed. The preparation method comprises the steps of epitaxial wafer cleaning, p-type Ga2O3 material layer preparation, cathode metal preparation, photoetching, p-type NiO film deposition, photoetching and anode metal preparation. N / P ion implantation is carried out on the upper portion of the gallium oxide epitaxial layer, Ga atoms in Ga2O3 are separated out and react again through high-temperature annealing to form the effective p-type characteristic, meanwhile, the effective p-type characteristic is combined with the p-type characteristic of p-type nickel oxide, p-type doping of gallium oxide is achieved through a simple process, the gallium oxide homogeneous pn junction is obtained, reliability is high, leakage current is small, and the gallium oxide homogeneous pn junction is suitable for large-scale production. The preparation method is used for preparing the p-Ga2O3 / n-Ga2O3pn junction diode with high voltage resistance.