53results about How to "Controlled release rate" patented technology

The invention belongs to the technical field of veterinary preparations, and particularly relates to a tilmicosin premix and a preparation method thereof. The tilmicosin premix is prepared from the following raw materials: tilmicosin, a polylactic acid-glycolic acid copolymer, lecithin, modified hydroxypropyl methyl cellulose, grafted polyvinylpyrrolidone, polyethylene glycol and an antioxidant, a solid dispersion is formed through lecithin and grafted polyvinylpyrrolidone, the solubility and stability of tilmicosin are enhanced, polylactic acid-glycolic acid copolymer nano-microspheres are prepared through a double-emulsion solvent evaporation method, slow release of drugs is achieved, dodecyl modified hydroxypropyl methyl cellulose and polyethylene glycol are combined, and the sustained release effect is achieved. The solubility and the slow release characteristic are further enhanced. The activity of the granular premix is effectively preserved, and the granular premix is convenient to use and transport.

The invention relates to a slow-release composite nanofiber mask with one-way moisturizing and oxidation resistance and a preparation method thereof.The one-way moisturizing nanofiber mask base cloth with asymmetric wettability is obtained through the preparation method, a hydrophilic layer adsorbs a nutrient solution and is dissolved when meeting water, a hydrophobic layer is kept dry, and the effect of delaying liquid volatilization is achieved; the effective time of the mask is prolonged. In addition, the nanofiber mask base cloth obtained through electrostatic spinning has good air permeability.

The invention relates to the technical field of medical supplies, and particularly discloses a therapeutic apparatus comprising an acupoint positioning unit comprising an excitation electrode and a measuring electrode, the excitation electrode is configured to generate current to human skin, and the measuring electrode is configured to receive the current and measure a resistance value of the skin to determine an acupoint position; the treatment unit comprises a polylactic acid layer, a temperature-sensitive hydrogel drug layer, a sensor and a plurality of microneedles, the temperature-sensitive hydrogel drug layer is arranged on the polylactic acid layer, the plurality of microneedles are arranged on the temperature-sensitive hydrogel drug layer in a rectangular array, and the sensor is arranged on the temperature-sensitive hydrogel drug layer among the plurality of microneedles; the host comprises a shell, a processor, a memory, a touch screen and an electric heater, the processor and the memory are in data connection and are both installed on a circuit board, the circuit board is arranged in the shell, the touch screen and the electric heater are installed on the shell and are in data connection with the processor, and the therapeutic instrument can achieve precise treatment and is convenient and reliable to use.

The invention relates to the technical field of organic fertilizers, in particular to a long-acting slow-release charcoal-based microbial compound fertilizer and a preparation method thereof. The long-acting slow-release biochar-based microbial organic fertilizer is prepared from the following raw materials in parts by mass: 10 to 20 parts of corn grit, 5 to 10 parts of coated biochar, 1 to 3 parts of monopotassium phosphate, 30 to 40 parts of livestock and poultry manure, 0.001 to 0.01 part of lanthanum ammonium nitrate, 30 to 40 parts of inorganic fertilizer, 0.2 to 0.3 part of microbial agent and 1.5 to 2 parts of epsilon-polylysine, the coated biochar is prepared by the following steps: adding biochar and dopamine hydrochloride into water, mixing, stirring at 30-40 DEG C for 20-30 minutes, adding tris (hydroxymethyl) aminomethane, stirring for 20-30 hours, centrifuging, washing, drying, crushing, feeding into a tubular furnace, keeping the temperature at 300-500 DEG C for 20-40 minutes under the protection of nitrogen, and cooling to room temperature.

The invention discloses a sodium alginate / chitosan microsphere for loading cells and a preparation method, the preparation method comprises the following steps: adding a pore-foaming agent into a sodium alginate solution, and stirring overnight to obtain a sodium alginate solution containing the pore-foaming agent; the preparation method comprises the following steps: dissolving chitosan in an acetic acid solution, adding calcium chloride, and stirring until the calcium chloride is completely dissolved to obtain a chitosan mixed solution; dropwise adding a sodium alginate solution containing a pore-foaming agent into the chitosan mixed solution, standing, and filtering to obtain a microsphere precipitate; soaking the microsphere precipitate in a hydrochloric acid solution until no bubble overflows, filtering, cleaning and drying; according to the sodium alginate / chitosan microspheres for loading the cells, natural polymer materials, namely the sodium alginate and the chitosan, are adopted, so that excellent biocompatibility is ensured, and the rejection reaction risk is reduced; through a calcium carbonate pore-forming technology, the microspheres have an accurate pore structure, so that loading of cells and stable release of drugs are facilitated, the release rate is controlled, and the treatment effect is improved.

The invention discloses a bone cement composite material with collapse resistance and a preparation method thereof, and belongs to the technical field of biomedical materials. The composite material comprises a solid phase part and a liquid phase part, the liquid phase part and the solid phase part are mixed according to the liquid-solid ratio of 0.35 mL / g to 0.6 mL / g; the solid phase part is composed of calcium sulfate powder and calcium phosphate powder, and the mass ratio of the calcium sulfate powder to the calcium phosphate powder is 85: 15; the liquid phase part is selected from carboxymethyl chitosan or a combination of carboxymethyl chitosan and sodium alginate. The bone cement composite material prepared by the preparation method disclosed by the invention has good biocompatibility; due to a gel network formed by carboxymethyl chitosan and sodium alginate, the compressive strength of the bone cement is remarkably improved, and the collapse resistance and injectable performance are excellent; meanwhile, the bone cement composite material promotes the attachment and proliferation of osteoblasts, and can induce osteogenic differentiation in vitro.

The invention discloses a polypeptide-coated anti-wrinkle composition containing a red camellia extract and application. The polypeptide-coated anti-wrinkle composition comprises a component A, a component B and a component C, wherein the component A is prepared from palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, polyhydric alcohol A and caprylic / capric triglyceride; the component B is prepared from PPG-13-decyl tetradecyl alcohol polyether-24 and polyhydric alcohol B; and the component C comprises water and a camellia japonica extract. According to the invention, the dissolvability problem of palmitoyl peptide is firstly solved, and then palmitoyl peptide is wrapped by a low-energy emulsification technology, so that the compatibility problem of the camellia japonica extract and palmitoyl peptide is solved, and a flowing liquid with a transparent appearance is obtained, is more stable and safer, has better effects, is convenient to apply, can promote the generation of collagen, and has a good application prospect. The activity of elastinase is inhibited, and the effects of improving wrinkles and delaying senescence are better achieved.

The invention discloses a preparation method of polylactic acid fibers for medical and sanitary materials, and relates to the technical field of polylactic acid fibers. Nano-crystalline cellulose, nano-graphite particles and polylactic acid are blended and crosslinked, the mechanical property of a matrix is enhanced, the antibacterial property is achieved, fibers are prepared through spinning, supercritical carbon dioxide treatment is conducted for the first time, the nano-graphite particles can play a role of a nucleating agent, polylactic acid is promoted to form fine and uniform crystals, and the mechanical property of the matrix is improved. Carbon dioxide is effectively wrapped in the foaming process, a micropore structure is formed in the fiber, the mechanical property of a matrix is enhanced, then secondary supercritical carbon dioxide treatment is conducted, the nano-silver is loaded into the matrix through supercritical fluid, the antibacterial property and the mechanical property are further improved, then the nano-silver is soaked in a silicate solution, dehydration is conducted, and the nano-silver fiber is obtained. A silica gel layer is formed on the surface of the fiber, so that the mechanical property and the antibacterial property of a matrix are enhanced.

The present application discloses a self-repairing super-hydrophobic nano anti-corrosion coating and a preparation method thereof, and relates to the technical field of anti-corrosion coatings, including a self-repairing super-hydrophobic nano anti-corrosion coating, which is composed of an organic fluorine-silicon modified acrylic resin, hydrophobic nano-SiO2, microcapsules containing particles of different particle sizes, xylene and a platinum-based catalyst, wherein the capsule core of the microcapsule is dimethyl silicone oil, a corrosion inhibitor mixture and nanoparticles, and the capsule wall is polyurea formaldehyde and micron particles; the corrosion inhibitor is benzotriazole; the nanoparticles and micron particles both include silicon dioxide and titanium dioxide; the particle size of the nanoparticles is nanometer-level, and the particle size of the micron particles is micron-level; the coating can be enhanced in hydrophobicity, the coating is not easily damaged for the second time, the service life of the coating is extended, and the repair efficiency and repair performance are improved.

The invention relates to a herbicide composition and a preparation method thereof, and relates to the technical field of agricultural herbicides, and the herbicide composition is prepared from the following raw materials in parts by mass: 40-50 parts of a herbicide drug-loading system, 3-5 parts of carbon black, 0.5-1 part of an anti-ultraviolet agent, 0.5-1 part of an antioxidant, 5-15 parts of a compound high-dispersity emulsifier and 10-15 parts of filler. The preparation method comprises the following steps: mixing carbon black, an anti-ultraviolet agent, an antioxidant and a filler, uniformly stirring, adding a herbicide loading system and a compound high-dispersity emulsifier, and uniformly stirring to obtain a mixture; and carrying out mechanical pulverization and airflow pulverization on the mixture, drying, screening and packaging to obtain the herbicide composition. The herbicide composition has the effect of improving the stability of the herbicide composition, the decomposition rate of the herbicide can be effectively reduced, and the weeding effect of the herbicide composition is improved.

The invention discloses a preparation method of a high-specific-surface-area polymer-based magnesium artificial wetland filter material. The preparation method comprises the following steps: firstly, respectively preparing a water phase containing magnesium salt and an emulsifier, and an organic phase; then slowly dropwise adding the water phase into the organic phase in a trickling filtration manner, so that the water phase forms tiny liquid drops in the organic phase, a polymerization reaction is carried out on an interface, and a magnesium ion embedded polymer matrix is formed; carrying out foaming treatment on the polymer matrix embedded with the magnesium ions, and rapidly cooling; and finally, separating a blank body through suction filtration, cleaning, drying and screening to obtain the filter material. The filter material obtained by the method disclosed by the invention can regulate the pH value of a water body and slowly release magnesium ions, enhance the nutrient supply of plants and improve the wetland function in a low-temperature environment, and has a high specific surface area.

This invention belongs to the field of biomedical technology, specifically relating to a pharmaceutical composition formulation containing ertapenem and its preparation method. The ertapenem-containing pharmaceutical composition formulation comprises the following raw materials: 10-20 parts ertapenem, 40-60 parts choline-leucine ionic liquid, 30-50 parts polyethylene glycol-polylactic acid-glycolic acid copolymer, 2-5 parts gluconolactone, 2-3 parts antioxidant, 40-50 parts deionized water, 3-5 parts surfactant, and 20-30 parts mannitol. This invention utilizes choline-leucine ionic liquid to enhance the solubility and stability of the polyethylene glycol-polylactic acid-glycolic acid copolymer with ertapenem, forming uniform micelles to protect the drug from hydrolysis. Liquid nitrogen freezing technology is used to improve preparation efficiency and product quality, ensuring biocompatibility.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition and a traditional Chinese medicine glasses frame. 10 to 20 parts of rhizoma acori graminei; 10 to 20 parts of polygala tenuifolia; 20 to 30 parts of menthol; 5-10 parts of clove; 10 to 15 parts of borneol; 10 to 20 parts of Chinese angelica; 10 to 20 parts of radix astragali seu hedysari; 5-10 parts of cassia oil; 10 to 20 parts of poria cocos; the traditional Chinese medicine composition fully embodies the compatibility principle of monarch, minister, assistant and guide. Ligusticum wallichii is used as monarch for promoting blood circulation to remove blood stasis; the rhizoma acori graminei and the polygala tenuifolia are used as minister Menthol, clove and borneol are used as assistants to enhance the drug effect; angelica sinensis and astragalus membranaceus are used as guide drugs to tonify qi and nourish blood. The combination not only can improve local symptoms, but also can regulate body functions on the whole, and embodies the thought of overall view and treatment based on syndrome differentiation of traditional Chinese medicine.

The invention belongs to the technical field of biology, and particularly relates to a tibinoside liver-targeting nano-liposome as well as a preparation method and application of the tibinoside liver-targeting nano-liposome. The liposome provided by the invention is prepared from a phospholipid membrane material, a cholesterol membrane material, functionalized phospholipid, hypericum japonicum, a liver targeting substance, a phosphate buffer solution, an organic solvent and the like. The hypericum japonicum liver targeting nano-liposome prepared by the invention can directly target liver parenchymal cells and bile duct epithelial cells, and improves liver functions and bile excretion by reducing the levels of ALT, AST, ALP, TBA, TBIL and gamma-GGT, improving mitochondrial structures and functions and inhibiting liver oxidative stress and inflammatory factors, thereby playing a role in treating cholestatic liver injury. The invention provides a novel medicine with exact curative effect and small side effect for clinically treating cholestatic liver disease.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine compound extract for improving oral environment and a preparation method and application thereof, and the traditional Chinese medicine compound extract comprises the following components in parts by weight: 10-15 parts of radix puerariae, 6-10 parts of coptis chinensis, 10-15 parts of honeysuckle, 10-15 parts of gallnut, 10-15 parts of scutellaria baicalensis, 10-15 parts of dandelion, 10-15 parts of wild chrysanthemum flower, 6-10 parts of raw liquorice, 10-15 parts of radix angelicae and 15-20 parts of asarum. The traditional Chinese medicine compound extract disclosed by the invention is green, natural and free of any chemical product, and by adopting a compound decoction extraction mode, the traditional Chinese medicine compound extract disclosed by the invention can more effectively enable medicines to exert the effects of monarch, minister, assistant and guide in a compound so as to achieve the effect of enhancing the effect.

The invention discloses an attached auricular point treatment patch and a preparation method thereof, and particularly relates to the technical field of medical devices, the attached auricular point treatment patch comprises a core medicine layer, a protective isolation layer and a fixing layer, the core medicine layer is covered with the protective isolation layer, and the fixing layer is attached to the other side of the protective isolation layer; the core medicine layer is prepared from the following raw materials in parts by weight: 5 to 20 parts of radix angelicae sinensis, 5 to 15 parts of radix achyranthis bidentatae, 3 to 10 parts of rhizoma gastrodiae, 3 to 8 parts of rhizoma atractylodis macrocephalae, 1 to 5 parts of radix ginseng, 2 to 6 parts of rhizoma chuanxiong, 0.5 to 3 parts of nano folium ginkgo extract, 0.5 to 2 parts of radix astragali seu hedysari extract, a viscous matrix accounting for 5 to 20 percent of the total weight and a penetration enhancer accounting for 1 to 5 percent of the total weight; and the protective isolation layer is made of a medical grade polyethylene or polypropylene film with the thickness of 0.01-0.06 mm. The auricular point treatment patch can stably and continuously release medicine and effectively permeate into auricular points to achieve a good treatment effect, meanwhile, the solubility and bioavailability of the medicine are remarkably improved, the treatment effect is enhanced, and the comfort level and the fitting degree are good.

The invention relates to the technical field of biomedical materials, and discloses a novel 5-aminosalicylic acid intercalated LDHs sustained release preparation and a preparation method thereof, and the novel 5-aminosalicylic acid intercalated LDHs sustained release preparation comprises a sustained release preparation laminate and a 5-aminosalicylic acid object, the sustained release preparation laminate comprises divalent metal ions (M < 2 + >), trivalent metal ions (M < 3 + >) and anions. The method is mild in experimental condition, simple to operate, free of toxic solvents and additives, free of complex synthesis and preparation processes, easy to process and suitable for large-scale production; the prepared 5-aminosalicylic acid intercalated LDHs sustained-release preparation has the characteristics of high drug loading capacity, good stability and remarkable sustained-release effect; the structure, composition and drug release rate of the 5-aminosalicylic acid intercalated LDHs sustained release preparation can be controlled by adjusting the synthesis conditions of the 5-aminosalicylic acid intercalated LDHs sustained release preparation, such as changing the intercalation mode, precipitator type, synthesis temperature and other factors.

The present invention relates to a compound of formula (I); a stereoisomer, a tautomer, a nitrogen oxide, a solvate, a metabolite, a pharmaceutically acceptable salt, a co-crystal or a prodrug thereof, or a pharmaceutical composition containing same; and the use thereof as a PB2 inhibitor in the preparation of a drug for treating related diseases. Each group in formula (I) is as defined in the description.         Cy1-L1-Cy2-L2-Cy3     (I)

The invention discloses a slow-release dressing for local surface long-acting anesthesia and a preparation method of the slow-release dressing, and belongs to the technical field of anesthesia dressings. The preparation method of the slow-release dressing for local surface long-acting anesthesia is used for solving the technical problems that in the prior art, the slow-release rate of an anesthesia dressing cannot be adjusted according to the tolerance of a patient to anesthetics, and the duration time of the anesthesia dressing needs to be further prolonged. Comprising the following steps: uniformly coating skin-friendly base cloth with anesthesia sustained-release gel to form an anesthesia sustained-release layer on the skin-friendly base cloth; coating the top of the anesthesia sustained-release layer with composite gel to form a water-absorbing and moisturizing layer; laying an antibacterial non-woven fabric on the top of the water-absorbing and moisture-preserving layer to obtain a primary anesthetic dressing product. The anesthesia sustained-release gel and the composite gel are matched with each other, so that the duration time of the anesthesia dressing is effectively prolonged, the release rate of the anesthetic in the anesthesia dressing can be adjusted according to the tolerance of a patient to the anesthetic, and the anesthesia effect of the anesthesia dressing is improved.

The invention provides a slow-release injection containing levosalbutamol and a preparation process thereof, the injection combines a ginkgo leaf extract, a resveratrol extract, vitamin B6, vitamin C, tea polyphenol and other auxiliary components, and through specific preparation steps, the injection can be prepared into the slow-release injection containing levosalbutamol. Comprising the following steps: preparing raw materials, mixing and dissolving, preparing a slow-release carrier, adjusting pH, filtering, filling, sterilizing and the like, thereby obtaining the injection with the slow-release effect. Wherein the ginkgo biloba extract and the resveratrol extract are obtained through specific extraction and purification steps, and the activity and purity of the ginkgo biloba extract and the resveratrol extract are ensured. Polylactic acid-glycolide (PLGA) is used as a sustained-release carrier material and is combined with the active component to form a stable sustained-release system. Every 20 ml of the injection contains 0.2-1 mg of levosalbutamol, and the injection is suitable for a treatment scene where the drug concentration needs to be maintained for a long time. The injection is simple and controllable in preparation process, the obtained product is good in stability and remarkable in slow release effect, and a new choice is provided for treatment of respiratory tract obstructive diseases.

The invention relates to the field of pesticide preparations, and particularly discloses a bacillus subtilis-containing bactericide for wheat and a preparation method of the bacillus subtilis-containing bactericide. The invention discloses a bacillus subtilis-containing bactericide for wheat. The bacillus subtilis-containing bactericide is prepared from the following raw materials in parts by weight: 13-18 parts of bacillus subtilis, 3-8 parts of sodium lignin sulfonate, 5-8 parts of lauryl sodium sulfate, 5-10 parts of urea, 60-70 parts of kaolin, 0.5-1.5 parts of an anti-blocking agent and 1-2 parts of a thickening agent. Kaolin serves as a carrier, the degradation phenomenon of bacillus subtilis in the storage and use process is reduced, the biological activity and sterilization efficiency of the bactericide are improved through the synergistic effect of all the components, and the prevention and treatment effect of the bactericide is prolonged.

The invention relates to the technical field of fertilizers, and discloses a high-molecular slow-release coating fertilizer, and a preparation method of a high-molecular slow-release coating comprises the following steps: S1, dissolving polyamide in N, N-dimethylformamide, adding a polyacrylic acid solution, adding benzoyl peroxide as a free radical initiator, and carrying out a grafting reaction; and S2, adding long-chain alkyl bromide into the grafted polymer, carrying out hydrophobic modification, stirring for 0.5-1.5 hours, slowly adding polyethylene glycol, carrying out hydrophilic regulation and control, and continuously stirring for 2-4 hours. According to the invention, the interaction between the fertilizer components and the polymer is increased through a method of grafting and modifying polyamide with polyacrylic acid, and pollution caused by excessive use of the fertilizer is reduced while the release of the fertilizer is slowed down by controlling the proportion of hydrophobic and hydrophilic groups in the polymer.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine compound extract for improving swelling and aching of gum as well as a preparation method and application thereof, and the traditional Chinese medicine compound extract comprises the following components in parts by weight: 15-20 parts of kudzuvine root, 10-15 parts of coptis chinensis, 15-20 parts of honeysuckle, 10-15 parts of gallnut, 10-15 parts of scutellaria baicalensis, 10-15 parts of dandelion, 10-15 parts of wild chrysanthemum flower, 6-10 parts of raw liquorice and 10-15 parts of pollen typhae. The traditional Chinese medicine compound extract disclosed by the invention is green, natural and free of any chemical product, and by adopting a compound decoction extraction mode, the traditional Chinese medicine compound extract disclosed by the invention can more effectively enable medicines to exert the effects of monarch, minister, assistant and guide in a compound so as to achieve the effect of enhancing the effect.

The invention discloses an antibacterial textile and a preparation method thereof. The antibacterial textile comprises the following raw materials in parts by weight: 100-120 parts of a textile; 100 to 130 parts of water; 4 to 8 parts of cocamidopropyl betaine; 8 to 16 parts of antibacterial microcapsules; 3-5 parts of a coupling agent; 3-7 parts of an accelerant; 3-8 parts of a softening agent; the antibacterial microcapsule comprises a capsule core and a capsule wall wrapping the capsule core; the capsule core is prepared from chitosan, nano silver ions and 2-octyl-2H-furan-5-ketone according to the weight ratio of (3 to 5) to (1 to 3) to (1 to 3); the capsule wall comprises melamine urea resin and ethyl cellulose. The antibacterial textile provided by the invention has the advantages of better antibacterial, mildew-proof and anti-pollution functions.

The invention discloses a multifunctional organic slow-release fertilizer based on a tea seed cake extract and a preparation method thereof. The multifunctional organic slow-release fertilizer based on the tea seed cake extract comprises the following components: 10-13 parts of the tea seed cake extract, 1-3 parts of a microbial agent, 2 parts of trace elements and 2 parts of a polymer slow-release agent. The multifunctional organic slow-release fertilizer is rich in various nutrient substances, environment-friendly, capable of effectively controlling the nutrient release rate and capable of remarkably enhancing the insecticidal effect.

Disclosed are a compound of formula (I), a stereoisomer, solvate, prodrug, metabolite, pharmaceutically acceptable salt, or eutectic thereof, or a pharmaceutical composition comprising same, and an application thereof as an ATX inhibitor in preparation of a drug for treating a related disease. Groups in formula (I) are as defined in the description.

The application provides a groove structure and a medical stent. The groove structure comprises a body, a groove and a drug coating. The groove is located on the body. A part of the outer surface of the body forms a shoulder, and the shoulder is located at at least one side of the opening of the groove. A part of the drug coating is accommodated in the groove, and another part of the drug coating covers at least a part of the shoulder. In this way, a part of the drug coating is accommodated in the groove, and another part of the drug coating covers at least a part of the shoulder. An operator can control the contact area of the drug coating with the vascular tissue by adjusting the drug loading of the shoulder and the thickness of the drug coating in the groove, thereby controlling the release rate of the drug coating.

The present application relates to the field of pesticide technology, and in particular to a composition containing fluorine oxazolidinone and chlorpyrifos, and a preparation method and application thereof. A composition containing fluorine oxazolidinone and chlorpyrifos, by mass, includes the following raw materials: 10-12 parts of active ingredients, 4-6 parts of composite surfactants, 2-3 parts of ethylene glycol, 4-5 parts of bio-based thickening adsorbents, 0.3-0.5 parts of defoamers, 4-5 parts of synergists, 2-3 parts of dispersants, 0.5-0.8 parts of preservatives, 5-6 parts of propylene glycol methyl ether acetate, and 65-70 parts of water; wherein the active ingredient is prepared by mixing fluorine oxazolidinone and chlorpyrifos with a mass ratio of (6-8): (4-6), and the synergist is a modified siloxane surfactant. The present application provides a composition containing fluorine oxazolidinone and chlorpyrifos, which has the advantages of synergistic enhancement, high selectivity, environmental compatibility, reduced environmental pollution, and cost savings in the prevention and control of beet armyworms, and is a safe, efficient, and environmentally friendly new pesticide.

The invention relates to soluble florfenicol powder and a preparation method thereof, and aims to improve the solubility and bioavailability of florfenicol. The method comprises the following steps: dissolving florfenicol powder in deionized water, and sequentially adding an emulsifier and a surfactant to form a stable emulsion; dissolving the pretreated chitosan in an acetic acid solution, and adding an antioxidant; and adding the florfenicol emulsion into the chitosan solution to form a microcapsule suspension, then adding a curing agent to carry out a cross-linking reaction, and finally carrying out freeze drying to obtain the soluble florfenicol powder. According to the method, the solubility and the bioavailability of florfenicol are remarkably improved, the stability and the oxidation resistance of the medicine are enhanced, the medicine release is controlled through a microcapsule technology, and the method has an important application prospect.