Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

121 results about "Bile duct" patented technology

A bile duct is any of a number of long tube-like structures that carry bile, and is present in most vertebrates. Bile, required for the digestion of food, is secreted by the liver into passages that carry bile toward the hepatic duct, which joins with the cystic duct (carrying bile to and from the gallbladder) to form the common bile duct, which opens into the intestine.

Hepatolithiasis negative pressure suction and laser lithotripsy integrated device

The invention belongs to the technical field of hepatobiliary calculus treatment, and discloses a hepatobiliary calculus negative pressure suction and laser lithotripsy integrated device which comprises a wrapping mechanism, and the wrapping mechanism comprises an abutting plate, a buffer pad, a connecting ring, a shell, a first cavity, a first vent groove, an air conveying pipe and a wrapping air bag; through cooperation of the wrapping air bag, the protective air bags and other structures, the calculus can be conveniently wrapped, the calculus is wrapped through the multiple protective air bags, an isolation layer is formed, the calculus is isolated from surrounding important tissues such as bile duct walls and blood vessels, and the calculus is prevented from being damaged. In the lithotripsy process, both energy generated by laser and splashing of stone fragments are limited in the protective air bag, damage to surrounding tissue is effectively prevented, meanwhile, the stone fragments can be prevented from being diffused to the surrounding tissue in the lithotripsy process, and complications such as bile duct blockage and inflammation are avoided. And subsequent negative-pressure suction operation is facilitated to thoroughly remove the dust.
Owner:HUNAN AEROSPACE HOSPITAL

Intravascular adjustable ultrasonic real-time navigation TIPS puncture instrument

The invention discloses an intravascular adjustable ultrasonic real-time navigation TIPS puncture instrument, and relates to the technical field of medical devices, the intravascular adjustable ultrasonic real-time navigation TIPS puncture instrument comprises a catheter sheath, a core-through needle catheter, a hollow core-through needle and a solid core-through needle; the core-through needle catheter penetrates through the interior of the catheter sheath; an operating handle is arranged at one end of the through core needle catheter, a traction mechanism is installed on the operating handle, and a pull wire is arranged in the catheter sheath. Real-time ultrasonic images are obtained through the ultrasonic probe, so that an operator can clearly see a needle point path, and key organs such as hepatic artery, bile duct and gall bladder are effectively avoided. The bending-adjustable puncture needle provides the capability of real-time correction in an operation, can easily cope with complex anatomical variation, can keep certain rigidity through the hardness adjusting chain after bending adjustment, improves the penetrating power of the puncture needle, prevents unpredictable mechanical deformation during liver cirrhosis liver puncture, enhances the controllability after bending adjustment, and improves the safety of liver cirrhosis. And accurate execution of the preset angle is ensured.
Owner:SHIYAN CITY PEOPLES HOSPITAL (PEOPLES HOSPITAL AFFILIATED TO HUBEI UNIV OF MEDICINE)

Method for forming access route to bile duct

A method of forming an access route to the bile duct includes: forming a tunnel extending from an oral ridge of a duodenal papilla, which is located on an oral side of a natural opening of a duodenal papilla, to the bile duct; and dilating a lumen of the tunnel more than when it was formed.
Owner:HIROYUKI ISAYAMA +1

System for evaluating curative effect of treating liver cancer by combining HDRBT with thermal ablation in multi-mode radiomics

ActiveCN120853956AMedical simulationImage enhancementTreatment sequenceExAblate
The invention discloses a curative effect evaluation system for treating liver cancer by combining HDRBT with thermal ablation in multi-modal radiomics, and relates to the field of liver cancer treatment, and the system comprises a multi-modal image data acquisition module which is used for collecting multi-modal image data; the three-dimensional visual model construction module is used for reconstructing a three-dimensional structure of liver tumors, peripheral blood vessels and bile ducts through an image segmentation algorithm, and generating a visual model by fusing radiomics characteristics; the combined treatment plan generation module is used for integrating the dosimetry parameters of the HDRBT and the process parameters of the thermal ablation, optimizing a catheter implanting path, the position of a thermal ablation electrode and a treatment sequence, and generating a combined treatment scheme; and the curative effect evaluation module is used for quantitatively analyzing tumor volume change, ablation boundary integrity and residual tumor activity through accurate registration of multi-modal images before and after treatment. According to the scheme, the problems of incomplete thermal ablation and high recurrence rate of hepatocellular carcinoma can be solved, and full-chain technical support is provided for clinical precise application.
Owner:ZHEJIANG CANCER HOSPITAL

A multi-functional catheter

The application provides a multifunctional catheter, comprising a catheter main body and a distal tube with a multi-cavity tube structure. The distal tube comprises a soft end at the proximal end and a functional end at the distal end. The catheter main body and the soft end are provided with a working cavity and a lens cavity. The functional end is further provided with a through hole communicating with the lens cavity. The lens cavity is a circular tube cavity structure extending along the catheter main body and the soft end. The inner wall of the lens cavity is provided with a plurality of accommodation grooves for accommodating photosensitive chips in a lens assembly. The catheter provided by the application can form a space for accommodating photosensitive chips through the plurality of accommodation grooves in the lens cavity, and the lens assembly can be installed without increasing the diameter of the lens cavity, thereby reducing the overall diameter of the catheter to adapt to the more complex bile duct environment relative to the digestive tract.
Owner:MICRO-TECH (NANJING) CO LTD

Bile duct cancer organoid model for drug screening and development or in-vitro simulation of bile duct cancer fibrosis progress and preparation method of bile duct cancer organoid model

The invention relates to the technical field of biomedical engineering, in particular to a bile duct for screening and developing drugs or simulating bile duct cancer fibrosis progress in vitro. The bile duct is prepared by the following steps: (1) treating a liver by using a lauryl sodium sulfate solution and a Triton X-100 solution in sequence, freeze-drying and crushing; (2) carrying out enzymolysis on the crushed tissues by using pepsin, and filtering to obtain acellular matrix hydrogel; and (3) mixing the acellular matrix hydrogel with a sodium alginate solution to obtain the composite hydrogel. The structure of the sodium alginate-acellular matrix composite hydrogel can be accurately controlled by adopting a 3D printing technology. Therefore, the hydrogel can better simulate a tumor microenvironment, and particularly can realize more real biocompatibility and tissue structure when being used for culturing bile duct cancer organs.
Owner:SICHUAN UNIV

Bile duct wall cell collection device

The utility model relates to the technical field of medical instruments, in particular to a bile duct wall cell collecting device. The bile duct wall cell collection device comprises a catheter, a main guide wire, an auxiliary guide wire and a cytobrush assembly. A first channel for the main guide wire to penetrate through and a second channel for the auxiliary guide wire to penetrate through are arranged in the catheter. And the auxiliary guide wire is parallel to the main guide wire. The cytobrush assembly is arranged in the axial direction of the main guide wire. The cytobrush assembly comprises a skeleton, a connecting frame, a base and a flexible guide rod. And the plurality of frameworks are circularly arranged along the axis of the main guide wire. One end of the skeleton is connected with the main wire. Bristles for collecting are distributed on the framework. The base sleeves the main guide wire and has the degree of freedom of sliding in the axial direction of the main guide wire. The base is connected with the framework through a connecting frame. One end of the flexible guide rod is connected with the base, and the other end of the flexible guide rod is connected with the auxiliary guide wire. The bile duct wall cell collection device can conveniently penetrate through the narrow part of the bile duct, the collection difficulty is reduced, and the sampling success rate is improved.
Owner:RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

CCL2 and receptor specific binding polypeptide thereof, and application of CCL2 and receptor specific binding polypeptide in prevention and treatment of cholestatic liver disease

The invention discloses CCL2, a receptor specific binding polypeptide thereof and application of the receptor specific binding polypeptide in prevention and treatment of cholestatic liver diseases, and relates to the technical field of biological medicines. The CCL2 and the receptor specific binding polypeptide thereof, which are screened by a molecular simulation technology, can be specifically bound with a key molecule CCL2 for inducing diseases and a plurality of receptors thereof in a cholestatic liver disease occurrence process, so that liver function indexes are recovered; the traditional Chinese medicine composition can be used for relieving liver pathological injury, including inhibiting bile duct hyperplasia, relieving portal vein inflammatory response and relieving portal vein fibrosis, so that the pathological development process of fibrosis and inflammation caused by the liver injury is blocked.
Owner:WUHAN UNIV

Free directional guide visual guide wire mirror device

The invention discloses a free directional guide visual guide wire mirror device. The device mainly comprises a handheld handle, an imaging optical fiber, an illumination optical fiber, a miniature view finding objective lens group, a photoelectric conversion image acquisition group, a flexible outer sleeve and a front-end free directional guide end, and the outer diameter of the device is smaller than 0.9 mm. And through a unique free directional guiding function, the visual probe can enter a superfine lumen and a narrow part for visual exploration on the premise of not damaging the mucous membrane of the cavity. The endoscope can be applied to medical scenes such as fallopian tube cavity examination, assistance of a duodenoscope in bile duct operation and the like, the application limitation of a traditional endoscope is effectively broken through, ray radiation hazards are reduced, the cross infection risk is reduced, and an innovative technical means is provided for medical diagnosis and treatment.
Owner:OUPAI MEDICAL TECH (GUANGZHOU) CO LTD

Biliary tract stent for univariate regulation and control of electron beam sterilization dosage and preparation method of biliary tract stent

The invention discloses a biliary stent for univariably regulating and controlling the dosage of an electron beam bactericide and a preparation method of the biliary stent, and belongs to the technical field of degradable biomedical materials and medical instruments. According to the stent, highly-oriented poly-L-lactic acid (PLLA) monofilaments serve as the unique raw material, and the self-expanding stent is woven after melt extrusion, solid-state thermal stretching and thermal setting; through univariate dose treatment of an electron beam sterilization (EBS) technology, the degradation rate and the degradation period can be precisely regulated and controlled in a gradient manner under the same process condition, and different clinical scenes such as gall bladder resection, biliary-intestinal anastomosis and biliary tract radiography can be matched respectively; the individual requirement of'etiological adaptation type 'is met, and a brand new normal form of single material, single variable and system one-way adjustment is provided for large-scale production and accurate application of the degradable biliary tract stent.
Owner:SOUTHEAST UNIV

Sophoridine tricyclic derivatives and use thereof in the preparation of a drug for resisting liver fibrosis or primary liver cancer

This invention discloses a sophoridine tricyclic derivative or its pharmaceutical salt, with the following general structural formula: R1 is selected from hydrogen, C1-C20 straight-chain alkyl, and C1-C20 branched alkyl. In vitro experiments have verified that the sophoridine tricyclic derivative can inhibit TGF-β-induced activation of hepatic stellate cells, improve CCl4- and bile duct ligation-induced liver injury and liver fibrosis in mice, inhibit TGF-β / Smads signaling pathway activation, and also inhibit diethylnitrosamine-induced primary liver cancer in mice. Therefore, this invention provides new evidence for the treatment, alleviation, or improvement of liver fibrosis or primary liver cancer using sophoridine tricyclic derivatives.
Owner:THE NAVAL MEDICAL UNIV OF PLA

Calculus removing device

The utility model relates to a calculus removing device, which comprises an outer pipe, an inner pipe and a calculus removing basket net or a calculus crushing rod, wherein the inner pipe can be sleeved in the outer pipe; the calculus removing basket net or the calculus crushing rod can be sleeved in the inner pipe; the calculus removing device is placed into a bile duct or a gall bladder through the expanded drainage pipeline, the calculus removing basket net is placed at the position of calculus through the inner pipe and the outer pipe, the calculus is sleeved with the basket net, the catheter is fixed, the basket net with the calculus is pulled outwards, and therefore the calculus can be crushed by clamping, and the calculus which cannot be crushed by clamping can be crushed by using the calculus crushing rod. Calculus fragments can be taken out of the body through the basket net.
Owner:SILVER BELL ENTERPRISE INC

Kudzuvine root active polysaccharide as well as preparation method and application thereof

The invention relates to the technical field of active polysaccharides, in particular to an arrowroot active polysaccharide as well as a preparation method and application thereof. In an infrared spectrum of the arrowroot active polysaccharide, the arrowroot active polysaccharide at least has characteristic absorption peaks at the following positions: 3317 cm, 2911 cm, 1404 cm <-1 >, 1021 cm <-1 > and 642 cm. The polysaccharide is extracted and separated from yam beans, and the polysaccharide has a protective effect in a mouse model with hepatic fibrosis induced by ligation of bile ducts, also has a regulating effect on intestinal microbiota, and exerts anti-fibrosis activity.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Reconstruction method for three-dimensional images of the liver, gallbladder and pancreas

The present invention relates to a method for reconstructing three-dimensional images of the hepatobiliary and pancreatic organs; the technical solution adopted by the present invention includes the following steps: introducing a segmentation network of a U-Net variant for the three organs of the liver, gallbladder, and pancreas, and using a convolutional neural network to segment multimodal images, including separating the liver, bile duct, and pancreas; introducing a boundary enhancement module during the segmentation process; adopting a deep learning-driven non-rigid registration algorithm to spatially align different-modal imaging data; using the anatomical feature points of the organs for registration; according to the registration results, performing multimodal fusion on the liver, gallbladder, and pancreas images, comprehensively utilizing the bone and tissue contrast of CT, the soft tissue resolution of MRI, and the real-time dynamic characteristics of ultrasound to construct fused imaging data; extracting the contours of the hepatobiliary and pancreatic organs from the segmented images to construct a preliminary three-dimensional grid model; adaptively adjusting according to the geometric shapes of different organs to control the distribution of the grid during reconstruction to match the organ morphology.
Owner:THE THIRD AFFILIATED HOSPITAL OF PLA NAVAL MEDICAL UNIVERSITY

Nipple sphincter incision knife with double guide wires

PendingCN120643280AIncision instrumentsMulti-lumen catheterAnatomyCommon bile duct dilatation
The invention provides a double-guide-wire nipple sphincter incision knife which comprises an outer sheath tube, a handle, a first guide wire, a second guide wire and a metal wire, and the first guide wire is inserted into the outer sheath tube through the tube wall of the outer sheath tube and penetrates out of the tube wall of the outer sheath tube; the handle is connected with the tail end of the outer sheath tube, and the second guide wire is inserted into the outer sheath tube through the handle and penetrates out of the head end of the outer sheath tube. One end of the metal wire is fixedly connected to the tube wall of the outer sheath tube, and the other end of the metal wire is inserted into the outer sheath tube and connected with the handle. During use, an assistant can implement the guide wire to assist the nipple sphincter incision knife in intubation into the pancreatic duct, an operator can operate the second guide wire to enter the common bile duct through intubation on the side wall of the duct wall on the basis that the duct diameter of the nipple incision knife is not increased, double-person multi-angle intubation is achieved, and the bile duct intubation success rate is increased.
Owner:SHANGHAI RUIFAN MEDICAL TECHNOLOGY CO LTD

Method for preparing wet-spun aligned collagen membrane with high tensile strength

PendingCN121181953ASpinningPolyethylene glycol
The invention discloses a method for preparing a wet spinning alignment collagen membrane with high tensile strength, and relates to the technical field of biomedical material preparation, the method comprises the following steps: preparing three layers of solutions, the upper layer and the lower layer are wet spinning buffer solutions (such as a polyethylene glycol solution) with specific concentration and pH, and the middle layer is a collagen solution with specific concentration and pH; injecting the three-layer solution into three-layer flow control equipment, and controlling the flow through a collecting tube; gathering the three layers of solutions at the tail end of equipment and performing wet spinning to form a film; and axially stretching to obtain a finished product. According to the invention, by precisely regulating and controlling a solution system, adopting industrial-grade flow control equipment and flow control, optimizing a directional stretching process and stabilizing a curing environment, the problems of non-uniform film thickness, easy tearing, large mechanical property fluctuation and the like in a traditional process are solved, large-scale production of the collagen film with high tensile strength and directionally arranged molecules is realized, and the production cost is reduced. The method is suitable for artificial blood vessels, bile ducts, skin and other tissue engineering fields.
Owner:张 育铭

Degradable bile and pancreatic duct stent

PendingUS20250295506A1StentsBlood vesselsPancreatic duct stentBile fluid
A degradable bile and pancreatic duct stent for dilating the narrowed lumen of a lesion, includes a guiding part, which has a guide passage through which a guide wire passes; and a stent main body, which is spirally distributed outside the guiding part in the lengthwise direction of the guiding part. The stent main body is capable of forming a spiral channel relative to the lumen, and the guide passage of the guiding part is in fluid communication with the spiral channel. The guiding part and the stent main body spirally have good bending and supporting performance, effectively drains bile, and prevent problems such as restenosis and occlusion in the bile and pancreatic duct. The guide passage is in communication with the spiral fluid channel, thus improving the drainage performance, and reducing the possibility of bile duct re-occlusion caused during the degradation process of the bile and pancreatic duct stent.
Owner:BEIJING ADVANCED MEDICAL TECH LTD INC

A kind of double (2,3-dihydroxy benzamide) compound and its preparation method and application

The application provides a kind of double (2,3-dihydroxy benzamide) compound and its preparation method and application, belong to medical technology field.The application obtains a series of double (2,3-dihydroxy benzamide) compound with novel structure and good inhibiting effect on cholestatic liver disease and liver fibrosis by structural modification of sporangium chelae, the compound can significantly inhibit the expression of hepatic stellate cell COL1A1 mRNA in vitro, has strong anti-liver fibrosis effect;In vivo, it can significantly alleviate the liver injury related biochemical indicators of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine (DDC) induced cholestatic liver disease mouse model, inhibit the expression of liver fibrosis related genes, reduce the content of liver collagen fiber, inhibit liver inflammation and bile duct response, and can be used for treating cholestatic liver disease and liver fibrosis.
Owner:MEDICINE & BIOENG INST OF CHINESE ACAD OF MEDICAL SCI

Novel choledochoscope without T tube

The invention discloses a novel choledochoscope without a T tube, and relates to the technical field of choledochoscopes, the novel choledochoscope comprises a forward extension structure, and the forward extension structure is arranged on the outer side of a choledochoscope pipeline in a sleeving mode; one end of the forward extending structure is connected to one end of the control handle; a displacement feedback mechanism is arranged in the front end of the choledochoscope pipeline and comprises a thin rope, one end of the thin rope is connected with an operation observation operation opening in the front end of the forward extending structure, and the other end of the thin rope is connected with the inner wall of the choledochoscope pipeline; the choledochoscope has the advantages that the forward extending structure and the displacement feedback mechanism are arranged on the basis of an original choledochoscope, the forward extending pipeline can extend forwards by a certain distance by rotating the rotary adjusting head, and by matching with the bending effect of the front end of the original choledochoscope, the purpose that the front end of the choledochoscope extends into a branch bile duct to observe and treat calculi can be achieved; the extending distance of the front end of the choledochoscope is fed back through the displacement feedback mechanism, so that the forward extending distance of instruments for subsequent calculus removal and the like is accurately controlled, and surgical operation is optimized.
Owner:马鞍山市人民医院

2-hydroxy-octadecene-9-cis-oate for use in the treatment of oncological pathologies and neuropathic pain

PendingUS20260115161A1Nervous disorderInorganic active ingredientsDiseaseUrachal cancer
The present invention relates to the compound 2-hydroxy-octadecene-9-cis-oate for use in the treatment of oncological pathologies including grade IV glioblastoma with native IDH, grade 3 glioma, embryonal tumour, pituitary tumour, meningioma, haemangiopericytoma, haemangioblastoma, mesothelioma, bile duct adenocarcinoma, exocrine pancreatic cancer, neuroendocrine pancreatic cancer, rectal cancer, urachal cancer, adenocarcinoma of the bladder and oesophageal cancer, and for the treatment of neuropathic pain caused by diabetic peripheral neuropathy, spinal cord injury, post-herpetic neuralgia, chemotherapeutic agent, antitumour agent, cancer, fibromyalgia or hepatitis. The present invention also relates to the pharmaceutical composition comprising 2-hydroxy-octadecene-9-cis-oate.
Owner:LAMINAR PHARMACEUTICALS SA

T pipe capable of being placed quickly

The utility model relates to the technical field of drainage, and discloses a T tube capable of being placed quickly, the T tube comprises a T tube body, an adjusting assembly is arranged in the T tube body, in order to enable the T tube to be placed more quickly, when the T tube body is installed, the two ends of a transverse straight part of the T tube body are folded towards the center, and the T tube body can be placed more quickly. The guide line is pulled, the guide line moves in the limiting ring, and the end part of the guide line pulls the fixing ring, so that the tension of the guide line can enable the fixing ring to limit the fixing rod, the two ends of the transverse straight part of the T-shaped tube body can be well folded and limited, and the folded part of the T-shaped tube body is put into the bile duct; the guide line is slowly loosened, the elastic force of the transverse straight part of the T tube body is slowly released to be opened in the bile duct, in this way, the T tube body can be placed into the bile duct more quickly, and the guide line cannot be collected into the T tube body due to the arrangement of the limiting block.
Owner:GUANGZHOU BAIYUN DISTRICT SECOND PEOPLES HOSPITAL

A biodegradable stent suitable for end-to-end anastomosis of bile duct in liver transplantation

The present invention discloses a degradable stent suitable for end-to-end anastomosis of bile ducts during liver transplantation, comprising a transverse stent assembly, a longitudinal stent assembly and a periodically degradable connecting assembly, a transverse tube body, a retaining net, a connecting sleeve, an end sleeve, an air-avoiding hole, a longitudinal tube body, a periodically degradable sleeve, and a periodically degradable filling block. Firstly, the transverse stent can achieve docking of donor bile ducts and recipient bile ducts of different diameters, thereby improving matching and applicability. The longitudinal stent can facilitate in vitro communication in the early stage of catheterization, thereby facilitating drainage and perfusion. Secondly, the periodically degradable sleeve and the periodically degradable filling block can be continuously degraded by the patient's body secretions and decompose after a certain period of time, thereby eliminating the docking between the transverse stent assembly and the longitudinal stent assembly, separating them, and facilitating the disassembly and removal of the longitudinal stent assembly. Finally, the grid structure of the retaining net can facilitate the accumulation of bioadhesives, thereby achieving the blocking of the retaining net. After the longitudinal stent assembly is separated from the transverse stent assembly, the transverse tube body in the transverse stent assembly is in a sealed state.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Transparent cap of choledochoscope

The transparent cap of the choledochoscope comprises a cap portion and a connecting portion, the tube wall of the front end, away from the connecting portion, of the cap portion is in an arc shape, and a first annular thread is arranged on the inner wall of the connecting portion. The choledochoscope tip is of a convex structure composed of a head part and a body part, the outer diameter of the head part is smaller than that of the body part, a second annular thread is arranged on the outer wall of the head part, and the second annular thread is connected with the first annular thread in a matched mode to achieve connection between the connecting part and the head part; and the outer diameter of the connecting part is the same as that of the body part. The transparent sleeve can be installed at the front end of a choledochoscope to carry out operations such as gall bladder or bile duct washing, calculus removal, stenosis expansion, gall bladder duct or Oddi sphincter exploration and the like; the transparent cap is firmly mounted and cannot fall off; the outer diameter of the connecting part of the transparent cap is consistent with the outer diameter of the choledochoscope body part, the tube wall at the front end of the cap part of the transparent cap is arc-shaped, and tissues such as fistulous tracts, gallbladders and bile duct mucosa are not damaged in the choledochoscope examination and treatment process.
Owner:SHANGHAI RUIFAN MEDICAL TECHNOLOGY CO LTD

Calculus taking-out device for hepatobiliary surgery

The invention relates to the technical field of medical instruments, in particular to a calculus taking-out device for hepatobiliary surgery, which comprises a sleeve, a net bag structure is mounted at one end of the sleeve, a driving assembly is mounted at the other end of the sleeve, the net bag structure comprises a bag body and a distraction assembly, and the distraction assembly comprises a fixing component and a transmission component; a partition plate is fixedly connected to the middle of the inner wall of the sleeve, a through groove is formed in the partition plate, a mounting frame is arranged on one side of the partition plate, a lead screw is rotationally matched with the mounting frame, the lead screw is in threaded connection with a nut seat, the nut seat is fixedly connected with a push block, a push rod is fixedly connected to one side of the push block, and the push rod penetrates through the through groove to be fixedly connected with a side plate. The transmission part is mounted on the mounting plate; one end of the screw rod is rotationally matched with the mounting frame, and the other end is fixedly connected with the driving assembly. The calculus capturing efficiency is improved, bile duct wall injuries and postoperative infection risks are reduced, and the requirements of minimally invasive surgery for instrument accuracy, stability and safety are met.
Owner:THE AFFILIATED HOSPITAL OF GUIZHOU MEDICAL UNIV

A visualization catheter and a cutting knife with the visualization catheter

The present invention relates to a visualization catheter for minimally invasive interventional surgery of the pancreatic and bile ducts, comprising a catheter body and a traction wire as an incision knife, wherein the distal end of the catheter body can be bent, turned and rotated under the action of the traction wire to change the insertion direction and angle, and the catheter body is provided with a visual lumen and a working lumen, wherein the visual lumen is provided with a micro video image sensor and an illumination element at the distal end of the catheter body, and the distal end of the catheter body is also provided with a transparent cap for ensuring the field of view and increasing the field of view angle of the camera module. The present invention, through the support of the micro video image sensor and the transparent cap, is helpful for finding the lumen and determining its running direction, accurately guiding intubation and related diagnosis and treatment, can perform intubation under direct vision, can distinguish the pancreatic duct and the bile duct by observing the image, reduces or avoids the time of exposure of the operating physician and the patient to radiation, can improve the success rate of selective intubation, and reduces the occurrence of complications.
Owner:石益海 +1

Cholangiopancreatography (CCP) suture removal knife

This invention provides a choledochoscope suture removal tool, comprising: an outer tube, a connecting rod disposed inside the outer tube, a blade, and a cutting section. The head end of the connecting rod is connected to the blade, and the tail end is connected to a handle. The handle is located at the tail end of the outer tube, and the cutting section is located at the head end of the outer tube or on the blade for cutting Purlin's suture knots. This invention can be inserted through the choledochoscope's forceps channel to cut residual Purlin's suture loops at the bile duct or choledochoenterostomy site.
Owner:SHANGHAI EAST HOSPITAL EAST HOSPITAL TONGJI UNIV SCHOOL OF MEDICINE

Device for removing biliopancreatic duct broken stone under endoscope

The utility model belongs to the field of lithotripsy devices, and particularly relates to a device for removing bile and pancreatic duct lithotripsy under an endoscope, which comprises a catheter and a handle, a support tube is fixedly connected inside the catheter, and a capillary tube is fixedly connected at one end of the support tube outside the catheter. A driving ring is fixedly connected to the end, away from the supporting tube, of the capillary tube, a guide wire is slidably connected to the interior of the supporting tube, an ultrasonic vibration head is fixedly connected to the end, away from the driving ring, of the guide wire, and a frame is fixedly connected to the upper end of the handle. The guide wire, the ultrasonic vibration head, the capillary tube and other structures are additionally arranged on the catheter, when calculus in the bile duct needs to be removed, the calculus in the bile duct can be shattered and refined through the ultrasonic vibration head, then the capillary tube is inserted into the rear portion of the calculus, and the calculus in the bile duct can be removed. And then the calculus is taken out from the interior of the bile duct through the deformed and expanded capillary tube, so that the calculus can be taken out more conveniently.
Owner:GUANGXI SHENGKANG MEDICAL TECH CO LTD +1

3D printing suture-free biliary-intestinal anastomosis stent for liver, gall and pancreas

The invention discloses a 3D printing suture-free biliary-intestinal anastomosis stent for liver, gall and pancreas. The 3D printing suture-free biliary-intestinal anastomosis stent comprises a connecting support, a fixing support and a fixing support, the middle joint is arranged between the connecting supports and used for connecting bile in the bile duct to the jejunum in sequence; the connecting support and the middle section are integrally formed, and the connecting support and the middle section are made of 3D printing degradable materials. Due to the fact that the straight-through type and suture-free blocking design is adopted, surgical operation is smooth, and B-ultrasonic detection shows that the biliointestinal anastomosis stent manufactured in the embodiment can be completely degraded within 3-6 months and does not need to be dismantled subsequently.
Owner:CHANGDE FIRST PEOPLES HOSPITAL

Marker for predicting curative effect of adjuvant therapy on tumor, kit and application

The invention provides a marker, a kit containing the marker, application of the marker and a use method of the marker. The marker comprises at least one selected from the group consisting of MUC1, MUC5AC, and Claudin18.2. The invention also relates to a method for preparing the marker. The marker and the kit containing the marker can be used for predicting prognosis of the intrahepatic cholangiocarcinoma, predicting the curative effect of targeted therapy and postoperative adjuvant therapy on the intrahepatic cholangiocarcinoma based on tumor expression states, and performing classified prediction on a big bile duct type and a small bile duct type of the intrahepatic cholangiocarcinoma. The disclosure also provides a method of cancer prognosis comprising detecting the expression of the marker and predicting the degree of benefit from post-operative adjuvant therapy in a subject, and / or the prognosis of cancer, particularly intrahepatic cholangiocarcinoma, in a subject. The present disclosure provides universal markers that can be used to predict the efficacy of postoperative adjuvant therapy, such as postoperative adjuvant chemotherapy, on intrahepatic cholangiocarcinoma.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI

Vision-RWKV architecture-based conventional ultrasonic image auxiliary diagnosis method and system for intrahepatic cholangiocarcinoma or tumor

The invention discloses an intrahepatic cholangiocarcinoma or tumor conventional ultrasonic image auxiliary diagnosis method and system based on a Vision-RWKV framework, and relates to the technical field of medical image auxiliary diagnosis. Comprising the following steps: acquiring image data information which is conventional liver ultrasonic image data of a plurality of existing patients; constructing an intrahepatic cholangiocarcinoma or tumor identification model based on a Vision-RWKV architecture, wherein the model has a linear complexity bidirectional attention mechanism; training an intrahepatic cholangiocarcinoma or tumor recognition model based on a Vision-RWKV framework by adopting the image data information; and inputting a conventional liver ultrasonic image of a patient to be identified into the trained intrahepatic cholangiocarcinoma or tumor identification model to obtain an identification result, wherein the result comprises a lesion type, lesion position calibration and credibility. The method has the advantages that ultrasonic examination is simple, economical and easy to operate, and CT / MRI examination is high in accuracy, so that more and wider crowds are covered and served, missed diagnosis and misdiagnosis are reduced, and patients obtain good prognosis and life quality.
Owner:THE FIRST AFFILIATED HOSPITAL OF HEBEI NORTH UNIV