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1 results about "Heparin coating" patented technology

Heparin coatings work by preventing platelet adhesion and activation, events that must be minimized to maintain blood compatibility. Heparin is a highly charged molecule that interferes with the blood-clotting mechanisms by catalyzing the inactivation of enzymes—such as thrombin and Factor X a—in the fibrin cascade.

A heparin coating and a preparation method, a vascular heparin-coated stent and a preparation method

PendingCN122141028APharmaceutical containersSurgeryHeparin coatingUltraviolet lights
The present application relates to the technical field of medical stents, and discloses a heparin coating and a preparation method, a vascular heparin covered stent and a preparation method, the heparin coating is prepared by introducing a photo-reactive group on a heparin molecule through substrate pretreatment, heparin modification, ultraviolet light curing and other modes, and the process does not use toxic reagents; the vascular covered stent comprises a wavy spiral, a flexible and stretchable stent body, an inner stent cylinder film and an outer silk stent covered film, a coating is coated on the inner surface of the cylinder film and the outer surface of the covered film, the vascular environment of long-distance and repeated bending of lower limbs can be met, the heparin coating is firmly combined, has long-lasting anticoagulation, effectively inhibits thrombosis, and greatly improves the safety and service life of the stent.
Owner:HEBEI KANGYU MEDICAL INSTR CO LTD