460 results about "Artificial heart" patented technology

Implantable prosthetic valve systems and methods for implanting them are provided. Magnets are employed within one or more components of the valve systems to facilitate anchoring of the prosthetic valve at a target implant site, delivery of the prosthetic valve to the target implant site or both.

The present invention relates generally to decellularized extracellular matrix of conditioned body tissues. The decellularized extracellular matrix contains a biological material, preferably vascular endothelial growth factor (VEGF), produced by the conditioned body tissue that is in an amount different than the amount of the biological material that the body tissue would produce absent the conditioning. The invention also relates to methods of making and methods of using said decellularized extracellular matrix. Specifically, the invention relates to treating defective, diseased, damaged or ischemic cells, tissues or organs in a subject by administering, injecting or implanting the decellularized extracellular matrix of the invention into a subject in need thereof. The invention is further directed to a tissue regeneration scaffold for implantation into a subject inflicted with a disease or condition that requires tissue or organ repair, regeneration and/or strengthening. Additionally, the invention is directed to a medical device, preferably a stent or an artificial heart, having a surface coated or covered with the decellularized extracellular matrix of the invention or having a component comprising the decellularized extracellular matrix of the invention for implantation into a subject, preferably a human. Methods for making the tissue regeneration scaffold and methods for manufacturing a coated or covered medical device having a component comprising decellularized extracellular matrix of conditioned body tissues are also provided.

An artificial heart valve and weaving method thereof are disclosed. The valve stent includes a tubular stent (10), valve leaflets (33), sealing membranes (351, 354), x-ray opaque markers (311, 312) and flexible connecting loops (41). The middle segment (15) of the net stent (10) is tubular or drum-shaped, or provided with radial protrusion structures (153), or provided with outer annular structures (155), or provided with outer free tongues (156), or provided with radial protrusion structures (153) and outer free tongues (156). The stent can be made by up and down interweaving the same one elastic metal wire, and also can be made by up and down interweaving different elastic metal wires. Moreover, the structure, shape and function of the valve stent are optimized; in radical compression, the valve can be transported to the right place with the help of interventional device; after expansion, fitted with figure of the vascular wall in the radical and axial direction, the artificial heart valve stent will not produce paravalvular leak; even more after implanting, the valve has a normal effect on prevent the slippage of artificial valve, which is caused by the blood reflux through the closed valve.

The present invention provides a human engineered power and control system for artificial hearts or assist devices configured for ease of use, ruggedness, and high reliability. Battery powered systems of the prior art have required multiple cables and connectors that are subject to failure due to damage or wear. In the present invention, direct connection of the batteries to the control system eliminates multiple cables and connectors used with previous designs. A novel method of connecting batteries to the control system and exchanging batteries without interruption of power is provided in a compact user friendly configuration. The control system may provide periodic reductions in assist device flow to permit the natural ventricle to eject blood through the natural outflow valve, open the valve leaflets to prevent them from adhering together, and achieve sufficient washout to prevent thrombosis. Using either software based control or software independent electronic circuitry, the flow pumped by the artificial heart is reduced for a long enough period of time to permit at least a few beats of the natural heart to generate sufficient pressure to open the outflow valve. In a control system embodiment in which the patient manually adjusts the pump speed to incremental settings for rest and exercise conditions, a pulsatile flow mode is disclosed which provides approximately the same flow at a given incremental setting as the pump produces when running in a constant speed mode at the same setting. As the patient learns which speed setting is best for daily activities, the patient may use the same setting with either a pulsatile or constant pump speed mode.

An artificial heart valve comprising a tubular base body having sinuse(s) of Valsalva and valve cusp(s) provided inside the base body, characterized in that the base body and the valve cusps comprise a bioabsorbable polymer material.

The invention relates to an artificial heart support valve, wherein it comprises tubular mesh support, valve blade, sealing film, impermeable x-ray mark, and flexible coiple ring; the middle part of mesh support is round or cylinder, or arranged with radial protrusion, or arranged with outer annular structure, or arranged with outer free tone, or arranged with radial protrusion and outer free tone. The invention can radial compress to transmit into accurate position via medium device, to be expanded, while the expanded valve will meet the shape of valve, without leakage. The invention can avoid being pushed when the blood refluxes and it is closed.

In an artificial heart valve for the replacement of an aortic or a mitral valve, including an annular body, which is provided at its outer circumference with means for mounting the artificial valve in place by surgical procedures and which defines in its interior a blood flow passage in which valve flap elements are pivotally supported so as to open or close the blood flow passage depending on their pivot positions, the annular body includes circumferentially spaced projections extending into the flow passage and being provided at their inner ends with pivot joints on which the valve flap elements are pivotally supported.

At least one aspect is directed to a totally artificial heart, and at least another aspect is directed to a method of controlling blood flow in a patient. The totally artificial heart may include a first rotary pump having an input to receive blood and an output to provide blood to a patient's lungs, a second rotary pump having an input to receive blood and an output to provide blood to the patient's body, a first sensor associated with the first rotary pump, a second sensor associated with the second rotary pump, and a control system coupled to the first sensor, the second sensor, the first rotary pump and the second rotary pump and configured to control characteristics of the first rotary pump and the second rotary pump based on signals received from at least one of the first sensor and the second sensor such that an average flow of blood through the second rotary pump is greater than an average flow of blood through the first rotary pump

Provided is an artificial heart control device for controlling a blood pump which assists flow of blood in a heart, the artificial heart control device including: a timing detection part which is configured to detect reference timing within a cardiac cycle of the heart; and a blood pump control part which is configured to control a rotational speed of the blood pump, wherein the blood pump control part controls, with reference to the reference timing detected by the timing detection part, the rotational speed of the blood pump such that the rotational speed becomes a rotational speed corresponding to a predetermined control pattern. According to the present invention, it is possible to provide an artificial heart control device, an artificial heart system and an artificial heart control method which can provide a load control optimum for the recovery of functions of a patient's own heart.

Devices and methods can be used for artificial cardiac pacing and/or resynchronization. For example, this document provides improved electrodes for stimulating and sensing electrical activity of the heart, and provides pacing and resynchronization systems incorporating such electrodes. While the devices and methods provided herein are described primarily in the context of pacing, it should be understood that resynchronization can additionally or alternatively be performed in an analogous manner, and that the scope of this disclosure includes such subject matter.

The invention relates to a magnetic suspension artificial heart pump, comprising a frame, a motor, a magnetic bearing and a blood pump blade wheel, wherein, the blood pump blade wheel, a motor rotor and a magnetic bearing rotary magnetic ring form a combined rotor to be mounted in a blood separating sheath with blood inlet and outlet, a motor stator, a fixed magnetic ring of the magnetic bearing and a radial displacement sensor combine a combined stator to be arranged at an outer ring of the blood separating sheath to be fixed with the frame. The invention realizes magnetic suspension on the rotor, with reliable operation, and uses blood separating sheath to avoid polluting blood from heart pump most. The invention has compact structure, small volume, better integration, long service life, and better transplant property.

A method of biolization to the surface of inorganic material includes the following steps: the surface is spattered to form a tantalum oxide or a titanium oxide thin film; and then the inorganic material is put in a plasma immersion ion implantation device; after vacuumization, hydrogen, water vapour or ammonia is fed in, with gas pressure 0.05 to 50 Pa; the radio frequency discharge power is 200 to 1200W; the range value of the loaded pulse high-voltage power is 1KV to 100KV, the frequency is 50 to 40000HZ, and the duty ratio is 3 percent to 80 percent; the heating temperature is 20 to 500 DEG C; the treatment time is 0.1 to 5 hours; finally, the inorganic material is put into 10 to 100mg/mL albumin or heparin solution to be soaked for 2 to 48 hours under 20 to 40 DEG C soaking temperature. The method does not damage the activity of the biomolecule and the protein; the prepared inorganic material with biolized surface has good anti-coagulability, is used for medical blood vessel scaffolds and artificial heart valves, and can greatly improve the product performance.

An auxiliary artificial heart pump drive device for driving an auxiliary artificial heart pump includes first and second pump control parts which are arranged in duplexed configuration. Each pump control part controls the auxiliary artificial heart pump by outputting a drive signal to the auxiliary artificial heart pump. Each pump control part has a means which, when a failure is detected in the pump control part, electrically cuts off a path through which the drive signal is outputted to the auxiliary artificial heart pump. According to the present invention, it is possible to provide an auxiliary artificial heart pump drive device and an auxiliary artificial heart system which exhibit high availability even when a serious failure occurs by any chance without duplexing a pump device.

A mitral annuloplasty ring that has a saddle shape with an upward bow in both an anterior segment and a posterior portion, with the upward bow being more pronounced in the anterior segment. The ring defines a closed ring body with a rounded isosceles triangular shape and the anterior segment along a long side. The posterior portion bulges outward to create a minor-major axis dimension ratio of between about 3.3:4 to 4:4. An inner ring body is made of a generally rigid material such as titanium that will substantially resist distortion when subjected to the stress imparted thereon after implantation in the mitral valve annulus of an operating human heart. The outward and upward posterior bow of the annuloplasty ring corrects for pathologies associated with mitral valve prolapse, as seen with Barlow's syndrome for instance, in which the leaflets tend to be elongated or floppy. The anterior segment has an enhanced upward bow to conform to systolic mitral annulus shapes, and the upward posterior bow is somewhat lower, for example between 1-2 mm lower, to help reduce the chance of suture pull-out, or dehiscence.

A polyurethane material containing F in side chain is prepared through alternative polymerization between the flexible chain segment consisting of polyether diol and/or polycarbonate diol and the rigid chain segment consisting of diisocyanate and chain-enlarging agent. Its advantages are high biologic stability and compatibility and high elasticity, strength and resistance to oxidizing and hydrolysis. It can be used for preparing artificial blood vessel, heart valve, etc.