101 results about "Artificial heart valve" patented technology

The application discloses a heart valve device and relates to the technical field of artificial heart valves, which comprises an outer valve frame and a valve leaflet assembly connected to the inside of the outer valve frame, and the outer valve frame is a ring-shaped grid frame; the outer valve frame comprises an inflow side grid frame and an outflow side grid frame arranged in sequence from an inflow end to an outflow end, and the inflow side grid frame and the outflow side grid frame form an annular recess for clamping a native valve ring on the outer periphery of the outer valve frame; the outflow side grid frame comprises a plurality of groups of grid support units connected in sequence along the circumferential direction and enclosed into a ring, and the grid support unit comprises an outer convex grid support and an inner concave grid support, and the outer surface of the inner concave grid support is arranged in a concave manner relative to the outer surface of the outer convex grid support. In this way, the anterior leaflet of the original mitral valve can be attached to the inner concave grid support, the extrusion of the outer valve frame on the anterior leaflet is reduced, the anterior leaflet is prevented from being extruded to the left ventricular outflow tract by the outer valve frame, and the outflow area of the left ventricular outflow tract is prevented from being reduced to cause obstruction.

Disclosed in the present application are an artificial heart valve, an interventional system, and a position registration method for an artificial heart valve. The artificial heart valve comprises: a stent, which is of a cylindrical structure and has a spatially axial direction, the interior of the cylindrical structure being a blood flow channel, and the stent being radially deformable so as to switch between a delivery state in which the stent is radially compressed and a deployed state in which the stent is radially deployed; valve leaflets, which are connected to the stent to control the blood flow channel; and a first radiopaque marker, which is connected to the stent. At the reference angle of viewing of the stent, when the stent rotates around its own axis, the distance between the projection position of the first radiopaque marker and the axis of the stent changes correspondingly.

The invention discloses an intelligent artificial heart valve integrated with pressure sensing, which comprises an implantation end and a body surface relay patch, the implantation end comprises a stent valve main body, a valve crossing pressure sensor pair, a microelectronic module and a flexible circuit, and the stent valve main body comprises a valve frame and a valve leaflet. The transvalvular pressure sensor pair comprises a first pressure sensor fixed to the ventricular proximal side of the stent valve body and a second pressure sensor fixed to the ventricular distal side of the stent valve body, leads of the pressure sensors are electrically connected with the microelectronic module through a flexible circuit, and the flexible circuit comprises a planar spiral coil; the plane spiral coil is electrically connected with the microelectronic module, the body surface relay patch comprises an external read-write coil, the external read-write coil transmits energy to the plane spiral coil, and the cross-lobe pressure sensor sends sensed data to the external read-write coil through the plane spiral coil. According to the invention, abnormal early warning can be realized, the treatment lagging is shortened, and the complication cost is reduced.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.

The present disclosure discloses a matching method and device of a heart valve and an electronic device. The method comprises: determining a plurality of target planes in a heart according to an anatomical structure image of the heart; determining a structural feature of the heart in each plane according to the anatomical structure image; determining a junction point in each target plane of the plurality of target planes according to the structural feature, wherein the junction point is a point at a junction edge between any two adjacent leaflets of the heart valve of the heart, and the junction edge is a connecting position between any two adjacent leaflets; determining a first push-away range corresponding to each target plane according to the junction point and the structural feature of the heart; determining a second push-away range corresponding to the heart valve according to the first push-away range corresponding to each target plane; and determining an artificial heart valve matched with the heart valve according to the second push-away range. The present disclosure solves the technical problem that the accuracy cannot be guaranteed due to the determination of the heart valve according to experience in the related art.

The application discloses a valve holder, an assembly and a valve loading system for delivering a prosthetic heart valve, wherein the valve holder for delivering a prosthetic heart valve comprises a connecting seat and at least one holding arm distributed on the outer periphery of the connecting seat, the at least one holding arm has a positioning structure at the distal end thereof, which matches the outflow side of the prosthetic heart valve; the at least one holding arm is provided with a frame for placing a binding wire for binding the prosthetic heart valve, the frame has a wire passing path and a wire cutting port corresponding to the wire passing path, and the wire passing path allows a wire segment of the binding wire extending along the wire passing path to be suspended. The optimized arrangement of the valve holder, the assembly and the system of the application avoids the interference of the valve holder with the holding, positioning and releasing process of the prosthetic heart valve, meanwhile, provides a structural basis for the arrangement of the surrounding matching components, optimizes the operation experience of medical staff and improves the treatment effect.

This invention discloses a novel valve stent and artificial heart valve, belonging to the field of medical device technology. The valve stent has a hollow, symmetrical, mesh-like tubular structure, with a first layer of hexagonal mesh groups, a second layer of polygonal mesh groups, and a third layer of polygonal mesh groups arranged sequentially from the outflow end to the inflow end. The stent has a small overall mesh count and symmetrical structure, resulting in uniform deformation during compression and expansion. It exhibits excellent radial support and minimal expansion rebound, significantly reducing the risk of paravalvular leakage. While maintaining radial support, this invention can reduce the stent strut width to 0.2–0.4 mm, and the minimum outer diameter of the valve after compression can reach 2.5–4.5 mm. Simultaneously, the overall length change during stent compression and expansion is minimal, greatly improving the smoothness of vascular delivery and the accuracy of valve implantation positioning. This meets the clinical needs of transcatheter aortic valve replacement surgery, enhancing the safety and effectiveness of artificial heart valve implantation.

A medical device that is adapted for excising a valve leaflet portion of a valve leaflet from a heart valve includes an elongate shaft including a distal region and an inflatable balloon that is secured to the distal region and that is adapted to extend through the heart valve. The inflatable balloon has an outer surface and includes a deflated configuration and an inflated configuration. An electrocautery electrode is disposed relative to the inflatable balloon such that the electrocautery electrode is positioned to excise the valve leaflet portion when RF energy is applied to the electrocautery electrode and the inflatable balloon is in the inflated configuration. In some cases, the heart valve includes an artificial heart valve. In some cases, the valve leaflet includes an artificial valve leaflet.

The present invention relates to an implantable artificial device, such as an artificial heart valve, and to a mounting configuration and method for attaching a soft component, such as a valve leaflet or skirt, to the frame of such an artificial valve. [Solution] The valve leaflets are connected to the struts of the frame via primary sutures, which are passed in an in-and-out pattern along the cusp end portion of the valve leaflets, and the secondary sutures are passed around the struts through the primary sutures and have a plurality of self-tightening structures configured to contract on the struts under tension.

This disclosure relates to an artificial heart valve for replacing a natural heart valve, comprising: an annular stent including: a mesh structure serving as a circumferential sidewall of the stent; and a leaflet structure, each leaflet being attached to the stent and having a first portion disposed within the stent and a second portion rolled up to the proximal peripheral side of the stent. As the heart grows, the stent can be expanded after the artificial heart valve is anchored to the heart, thereby allowing the artificial heart valve to function in different states without replacement. The edge end of the second portion of each leaflet is connected to the stent at a location between the distal and proximal ends of the stent, but not fixed to the proximal end of the stent. In at least one state, the size of each leaflet exceeds the fit size of the stent in that state, and each leaflet has a redundant portion that hangs freely from the distal to the proximal end to a location away from the stent, thereby allowing the leaflet to be sized away from the stent to form a more functional valve.

The application discloses a heart valve releasing mechanism, a releasing catheter and an artificial heart valve conveying system. The heart valve releasing mechanism is used for clamping and releasing an artificial heart valve and comprises a clamping jaw, a moving part and a clamping jaw. The clamping jaw comprises a first clamping arm and a second clamping arm which are arranged at intervals. The moving part has a moving space. At least a part of the first clamping arm and at least a part of the second clamping arm are movably arranged in the moving space. The clamping jaw has a clamping state and a releasing state. In the clamping state, at least a part of the artificial heart valve is clamped between the first clamping arm and the second clamping arm. In the releasing state, the distance between the first clamping arm and the second clamping arm is increased, and the artificial heart valve can be separated from the clamping jaw. The clamping jaw can be switched between the clamping state and the releasing state by moving the moving part relative to the clamping jaw. The releasing mechanism has simple structure and convenient operation, and can facilitate the assembly and disassembly of the artificial heart valve.

The present application relates to a kind of artificial heart valve stents and artificial heart valve.The artificial heart valve stent includes inner support and outer support.Inclination from inflow end to outflow end, first portion and second portion are included in sequence in inner support, the radial dimension of first portion is greater than the radial dimension of second portion, at least a portion of second portion is nested in outer support, and at least a portion of first portion extends to inflow end relative to outer support, and the portion of first portion extending to inflow end relative to outer support covers flow blocking film.The artificial heart valve includes the artificial heart valve stent and artificial valve leaflet fixedly connected in inner support.The artificial heart valve stent and artificial heart valve can reduce the risk of paravalvular leakage while being stably positioned in heart.

A device for treating a diseased native valve in a patient is provided, the device comprising: a frame structure; valve segments radially arranged within the frame structure, the valve segments including a plurality of leaflets; and a plurality of commissure attachment mechanisms coupling the leaflets to the frame structure, each commissure attachment mechanism extending radially inward from the outflow end of the frame structure to form a gap between an inner diameter of the outflow end and an outflow edge of the valve segment. Other embodiments and methods of use are also provided.

1. Name of the product in this design: Cardiac stent. 2. Purpose of this design: This design is used to maintain or connect to an artificial heart valve. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

An artificial heart valve comprises a frame, a plurality of flexible leaflets attached to the frame, and a plurality of support members, each support member being attached to a corresponding leaflet. The leaflets are movable relative to the frame between an open configuration, in which the leaflets permit blood flow therebetween in a direction having at least a component in a forward direction, and a closed configuration, in which the leaflets prevent or restrict blood flow therebetween in a direction having at least a component in a backward direction which is opposite to the forward direction. The support members are movable with the leaflets relative to the frame. When the leaflets are in the closed configuration and exposed to a back pressure having at least a component in the backward direction, a force is exerted on the leaflets in the backward direction, and the support members at least partially prevent or resist deformation of the leaflets. A leaflet arrangement for an artificial heart valve and a method of manufacturing an artificial heart valve are also disclosed.

The invention relates to an artificial heart valve having a two-part design, consisting of an outer artificial heart valve having means for permanently anchoring the artificial heart valve at the implantation site and an inner artificial heart valve, which can be replaced independently of the outer artificial heart valve anchored at the implantation site and can be inserted into the outer artificial heart valve and which has artificial heart valve cusps, wherein the outer artificial heart valve has formations for defined placement of the inner artificial heart valve and the inner artificial heart valve for anchoring the inner artificial heart valve in the outer artificial heart valve. The invention also relates to a device for performing a catheter-based implantation of an artificial heart valve, to a method for explanting an artificial heart valve, and to a method for reimplanting an artificial heart valve.

The invention discloses an artificial heart valve with a clamping structure. The artificial heart valve comprises a first valve seat body, a second valve seat body and an artificial valve leaflet, the second valve seat body is arranged on the outer side of the first valve seat body, and the artificial valve leaflet is arranged between the first valve seat body and the second valve seat body; the second valve seat body is provided with a parting line, the midpoint of the parting line intersects with the central axis of the second valve seat body, and the parting line divides the second valve seat body into two halves. The overall symmetry of the artificial valve is improved, meanwhile, the influence of traditional suture on the peripheral suture edge part of the artificial valve leaflet is avoided, and the service life of the artificial heart valve is prolonged. Meanwhile, the replicability and quantitative production of the whole structure of the artificial valve are guaranteed, and the production efficiency is improved.

The utility model discloses an artificial heart valve testing device, and relates to the technical field of medical instrument detection, the artificial heart valve testing device is characterized in that a first end of a high-transparency compliance valve testing cavity is connected with a first pipeline connecting piece, a second end is connected with a second pipeline connecting piece, and a high-transparency compliance valve model is fixed in a device main body; a simulated native valve clamp is arranged in the high-transparency compliance valve testing cavity, and the simulated native valve clamp clamps an artificial heart valve in the high-transparency compliance valve testing cavity. The first pipeline connecting piece and the second pipeline connecting piece can be connected with an external pipeline, so that the blood flowing environment of a human body can be simulated in the high-transparency compliance valve testing cavity; meanwhile, the simulated native valve and the artificial heart valve are both located in the simulated human body blood flowing environment, the performance of the artificial heart valve implanted into the simulated native valve can be simulated, and the potential risk after the artificial heart valve is implanted is evaluated.

The invention discloses an intervention system for preassembling a heart valve prosthesis, which comprises a heart valve prosthesis and an intervention conveying system, the intervention conveying system comprises a conveying sheath tube, a core tube and a control handle, the conveying sheath tube comprises a tube body and an operation handle fixedly connected to the near end of the tube body, and the far end of the tube body is provided with a storage bag which is communicated with the tube body and is in running fit with the tube body; the operation handle is provided with an avoiding channel communicated with the pipe body. The core tube is arranged in the conveying sheath tube in a penetrating mode, the heart valve prosthesis is compressed and loaded in a radial gap between the core tube and the containing bag, and the core tube and the conveying sheath tube can slide relative to each other so that the heart valve prosthesis can be exposed out of the containing bag and released. The near end of the core tube extends out of the avoiding channel and is connected with the control handle, the control handle drives the heart valve prosthesis and the storage bag to rotate relative to the operation handle through the core tube so as to adjust the circumferential position of the heart valve prosthesis, the operation safety and controllability are improved, and the operation flexibility is guaranteed.

The invention discloses an anti-calcification heart valve prosthesis and preparation thereof, and particularly relates to the field of heart valve prosthesis application. The preparation method comprises the following steps: soaking a bacterial nano cellulose membrane (BNC membrane) in a polyvinyl alcohol (PVA) solution, and then carrying out freezing phase separation after-treatment, thereby obtaining the bacterial nano cellulose membrane. The preparation method comprises the following steps: preparing a film-shaped BNC material; soaking the BNC membrane with the moisture removed in a polyvinyl alcohol solution; performing phase separation treatment on the BNC membrane containing the polyvinyl alcohol solution; removing residual impurities on the surface of the composite membrane; suturing the artificial heart valve prosthesis; according to the preparation method, the thickness of the BNC membrane can be reduced, so that the thickness of the composite membrane is reduced, the mechanical property, anticoagulation and anti-calcification properties of the composite membrane are improved, and the preparation method has great application potential in the field of artificial heart valves.

To provide a prosthetic heart valve device, system, and methods.SOLUTION: A system is provided, comprising a prosthetic heart valve device (535, 555, 900, 1108, 1230, 1260, 1400, 1535), and a delivery system (1100, 1105, 1110, 3000, 1500). The prosthetic heart valve device (535, 555, 900, 1108, 1230, 1260, 1400, 1535) comprises a differentially deformable anchoring structure (800, 1229, 1259) concentrically aligned with, radially adjacent to, and in direct connection with a valve frame (700). The atrial region (805, 1005, 1410, 1805, 1850) of the differentially deformable anchoring structure (800, 1229, 1259) comprises a plurality of alignment structures intended to aid in rotational orientation. This atrial region (805, 1005, 1410, 1805, 1850) is in direct connection with the valve frame (700) through inflow region connection elements (745).SELECTED DRAWING: Figure 8D

The present application relates to the field of medical devices, and provides an artificial heart valve frame, a double-layer artificial heart valve frame and an artificial heart valve prosthesis, comprising a framework, an upper anchoring structure and a lower anchoring structure, the framework comprises a valve frame main body, the upper anchoring structure is connected with the upper end of the framework and extends to the outside of the valve frame main body; the lower anchoring structure is connected with the lower end of the framework and extends to the outside of the valve frame main body. When the artificial heart valve frame changes to a radial contraction state, the upper anchoring structure elastically folds in the direction of downward and close to the valve frame main body; the lower anchoring structure elastically folds in the direction of upward and close to the valve frame main body. The present application alleviates the technical problem that the length of the existing valve frame is relatively long after compression, which affects the success rate of operation and the operability of the transseptal puncture approach mode for operation, and at the same time, the surgical risk can be reduced.

This application discloses a testing system and method for artificial heart valve implants, relating to the field of medical device testing technology. The system includes: a ventricular simulator, an atrial simulator, a highly transparent and compliant valve testing chamber containing an artificial heart valve, a vascular compliance simulator, and a vascular damping simulator forming a circulation loop, a high-speed camera, and a laser generator. The circulation loop simulates the blood flow environment of the artificial heart valve, with a tracer particle suspension added to the flow medium. The ventricular simulator, atrial simulator, vascular damper, and vascular compliance simulator provide power, storage space, resistance, and pulse pressure to the flow medium, respectively. The laser generator and high-speed camera work together to acquire particle images after implantation of the artificial heart valve. The particle images are uploaded to a computer for visual analysis of the heart valve pulsating flow field based on digital particle image velocimetry technology, thereby enabling quantitative analysis of the risk after implantation at the intended site.

The invention discloses a valve frame ironing mold, an artificial heart valve frame ironing device and an ironing method. The petal frame ironing mold comprises a first mold, a second mold and a heating piece, a first containing groove is formed in the first mold, a second containing groove is formed in the second mold, and the first mold is provided with a first position and a second position; when the first mold is located at the first position, the first mold and the second mold are in a mold closing state, and at the moment, the first containing groove of the first mold and the second containing groove of the second mold are correspondingly arranged and matched to form a mold groove used for containing an artificial heart valve frame; when the first mold is located at the second position, the first mold and the second mold are in a separated state; the heating piece is connected with the first mold and / or the second mold and conducts heat to the first mold and / or the second mold. According to the petal frame ironing mold, after the petal frame is wrapped with the fabric, the fabric can be ironed and formed to obtain the sewing edge so as to meet the requirement for dissecting and sewing, and the ironing efficiency can be improved.

The artificial heart valve device comprises a support and valve leaflets, the whole support is of a tubular structure and is provided with a hollow area, a blood flow channel is formed in the support, the number of the valve leaflets is multiple, and the valve leaflets are located in the blood flow channel and matched with one another so as to oppositely open or close the blood flow channel; the support is further provided with peripheral leakage preventing components, and the peripheral leakage preventing components are block-shaped distributed at intervals and correspond to the hollowed-out areas in position. The support has a compression state and an expansion state which are opposite to each other, in the expansion state, the peripheral leakage prevention components protrude out of the outer peripheral face of the support, in the same peripheral leakage prevention component, the thickness is gradually increased from the outflow side to the inflow side, the thickness is gradually reduced after the thickness reaches the highest protruding part, and the part with the largest protruding height is closer to the inflow side.

The invention relates to a mitral valve outer valve frame, a mitral valve frame assembly and a heart valve prosthesis. The invention relates to a ventricular atrial cavity which has a radial contraction state and a radial expansion state and comprises an atrial part, a ventricular part and a connecting frame, the atrial part and the ventricular part are connected through the connecting part, and the atrial part and the ventricular part are of a latticed structure and comprise frame units; the ventricular part comprises at least three protruding parts which are distributed at intervals in the circumferential direction, an avoiding space is formed between every two adjacent protruding parts, the area of the avoiding space is gradually increased in the direction from the inflow end to the outflow end, and due to the fact that an avoiding area formed between every two adjacent supporting pieces has small influence on the ventricular autologous structure, the ventricular autologous structure can be effectively improved. The avoiding area is aligned with the left ventricular outflow tract during anchoring, so that the problem that the left ventricular outflow tract is blocked due to deformation after the mitral valve outer valve frame is implanted is solved.

The invention provides an artificial heart valve stent and an artificial heart valve prosthesis, and relates to the field of medical instruments, the artificial heart valve stent comprises a stent main body, a stent outflow section and a bending arm; the near end of the stent outflow section and the far end of the stent main body are integrally formed; the bent arm is arranged on the support body and extends in the circumferential direction of the support body, the bent arm is provided with a bent arm connecting end and a bent arm free end in the circumferential direction of the support body, the bent arm connecting end and the support body are fixedly connected or integrally formed, and the bent arm free end and the support body are spaced. The heart valve prosthesis prosthesis comprises an inner stent and an outer stent, and the inner stent or the outer stent is the heart valve prosthesis stent. According to the artificial valve, the risk of perivalvular leakage after the artificial valve is implanted in an interventional mitral valve replacement operation can be reduced.

To provide a catheter with a suitable integrated embolic protection device. [Solution] The artificial heart valve delivery catheter includes an embolic filter to provide integrated embolic protection to prevent the release of embolus into the aorta, aortic arch, or branch vessels and other vascular systems during transvascular heart valve replacement procedures. The embolic filter will typically be fixed or movably attached to the shaft of the delivery catheter proximal to the artificial heart valve.

A kind of artificial heart valve steady flow testing device and testing method.Improvements are made to the artificial heart valve steady flow testing system technology.The existing testing device is not stable in operation, and has unreliable performance, low precision, and is not easy to replace the measured valve, and is complex to operate and other technical problems.The device of the present application, energy storage medium tank is connected to the inlet of throttling branch and valve two, valve two is connected to the inlet of valve test circuit, the outlet of valve test circuit is connected to forward flow test circuit A and regurgitation test circuit B in parallel through valve, forward flow test circuit A and regurgitation test circuit B are connected to the outlet of throttling branch and medium storage tank.For forward and regurgitation characteristics, the test channel is set to two orders of magnitude channels that can be switched, reducing data error.No need to remove the pipeline to replace the measured valve.Parallel forward flow and regurgitation nozzle are used, without changing the nozzle, two kinds of tests can be realized on a set of testing equipment, effectively improving work efficiency and reducing testing cost.

The application provides an artificial heart valve composite material and a preparation method thereof. The composite material can be prepared by the following steps: firstly, preparing a thermoplastic polymer film on a low-barrier smooth substrate; and then using the clamping effect of the polymer film on the fabric; or firstly, forming a thermoplastic polymer film on the surface of the fabric; and then using a good solvent of the thermoplastic polymer film to partially dissolve the thermoplastic polymer film; under the fixing effect of the low-barrier smooth substrate, the polymer film is solidified again, and the polymer film and the fabric are combined, so that the artificial heart valve composite material is finally prepared. By using the preparation method provided by the application, the prepared composite material has a smooth and uniform surface, the fabric and the polymer layer are combined tightly, and there is no obvious interface.