306 results about "Artificial heart valve" patented technology

The invention discloses a test system and method for an artificial heart valve implant, and relates to the technical field of medical instrument detection. The system comprises a ventricle simulator, an atrium simulator, a circulation loop, a high-speed camera and a laser generator, wherein an artificial heart valve is arranged in the high-transparency compliance valve testing cavity, and the circulation loop is composed of a blood vessel compliance simulator and a blood vessel damping simulator. The circulation loop simulates a blood flowing environment for the artificial heart valve, and a flowing medium is added with tracer particle turbid liquid; the ventricle simulator, the atrium simulator, the vascular damper and the vascular compliance simulator respectively provide power, storage space, resistance and pulse pressure for the flowing medium; and the laser generator and the high-speed camera act together to obtain a particle image behind the artificial heart valve. The particle image is uploaded to a computer for heart valve pulsating flow field visualization analysis based on the digital particle image velocity measurement technology, and therefore quantitative analysis of the risk after the heart valve is implanted into the expected position is achieved.

An embodiment of a radially contractible and expandable artificial heart valve is disclosed. When mounted on a delivery shaft, the valve frame may have a tapered profile, with the inflow end portion having a smaller diameter than the outflow end portion. The valve may include a generally V-shaped leaflet, reducing material in the inflow end of the frame. An outer skirt may be fixed to the outside of the inflow end portion of the frame, the outer skirt having a longitudinal slack when the valve is expanded and lying flat against the frame when the valve is contracted. The diagonally braided inner skirt may be axially elongated with the frame. Side protrusions adjacent to the leaflets may extend through and be fixed to the window frame portion of the frame to form a commissure. When the valve is creased on the delivery shaft, the window frame portion may be radially recessed inward relative to the surrounding frame portion.

A catheter implant system (61) and related devices, prosthetic heart valves (65, 7200) and methods included therein, relating to the technical field of medical instruments wherein an interventional delivery system (1, 51) included therein comprises a catheter assembly (30, 54, 64) and a control handle (9, 20, 53, 63, 63a, 63b) connected to the catheter assembly (30, 54, 64), the catheter assembly (30, 54 and 64) is provided with a far end and a near end which are opposite to each other and comprises an inner sheathing canal (320) and an outer sheathing canal (310, 544 and 644) which are sleeved with each other in a sliding mode, the outer sheathing canal (310, 544 and 644) sequentially comprises a loading section (3102) and a sheathing canal section (3103) from the far end to the near end, and the loading section (3102) is used for wrapping the interventional instrument and keeping the interventional instrument in a compressed state; the control handle (9, 20, 53, 63, 63a, 63b) comprises: a main handle (10) to which the proximal end of the inner sheath (320) is connected; the auxiliary handle (20) is arranged on the periphery of the inner sheath tube (320) in a sliding and sleeving mode, and the near ends of the outer sheath tubes (310, 544 and 644) are connected to the auxiliary handle (20).

The invention belongs to the technical field of medical instruments, and particularly relates to an artificial heart valve which comprises a support and a valve leaflet mechanism. A plurality of bracket connecting holes are formed in the bracket; the valve leaflet mechanism comprises a plurality of connecting pieces and artificial valve leaflets; the artificial valve leaflet is provided with a valve leaflet main body, two first connecting parts and two second connecting parts, each connecting piece penetrates out of the corresponding support connecting hole from the inner side of the support after being folded and is attached to the two sides of the periphery of the support connecting hole, every two adjacent fixing parts are connected with the two sides of the corresponding connecting piece respectively, and the arc-shaped parts can be attached to the surface of the valve leaflet main body. After the artificial valve leaflet and the support are fixed, in the open state of the artificial valve leaflet, the arc-shaped part attached to the outer wall of the artificial valve leaflet can play a role in buffering the artificial valve leaflet, and the artificial valve leaflet is protected.

The invention discloses an artificial heart valve near-physiological pulsation fluid external evaluation device and method, and relates to the technical field of heart valve testing.The artificial heart valve near-physiological pulsation fluid external evaluation device comprises a supporting frame, a driving unit, a tested valve installation unit and an artery and peripheral loop unit, the driving unit provides power for liquid flowing, and the tested valve installation unit is used for fixing an artificial heart valve; and a liquid volume assembly and a resistance assembly of the artery and peripheral loop unit can simulate the compliance and resistance of aorta blood vessels and peripheral artery blood vessels, so that the pressure waveform simulation of the systemic circulation loop is more accurate. On the basis of the air cavity, the elastic corrugated pipes with different frequency responses are arranged, the compliance and rebound resilience of the aorta are simulated, a device for rapidly replacing the tested valve is designed, and the mechanical property of the simulated human body aorta is adjusted by adjusting the parameters such as the output frequency and the vibration amplitude of the driving unit; real pressure and flow waveforms under different physiological / pathological conditions are simulated, and a more accurate and convenient detection environment is realized.

The utility model provides a valve stent and an artificial heart valve prosthesis, the artificial heart valve comprises the valve stent, the valve stent is provided with an inflow end and an outflow end which are opposite to each other, and the valve stent comprises a main stent and a plurality of clamping mechanisms which are arranged at intervals along the circumferential direction of the main stent and are connected with the outer circumferential surface of the main stent; the clamping mechanism comprises a first clamping body and a second clamping body which are arranged in the direction from the inflow end to the outflow end. The first clamping body and the second clamping body are used for clamping the native valve leaflet so that the heart valve prosthesis can be anchored in the heart, the anchoring of the heart valve prosthesis can be achieved without extruding the valve ring in the radial direction through the main support, and the situation that native tissue such as the valve ring is damaged due to radial extrusion is avoided.

The invention belongs to the technical field of biological medicine, and particularly discloses an artificial valve tissue calcification model and a preparation method and application thereof. The preparation method comprises the following steps: providing human valvular interstitial cells; the method comprises the following steps: providing a hydrogel system, wherein the hydrogel system comprises type I collagen, fibrinogen and Matrigel matrigel; constructing an engineered heart valve tissue strip by taking the hydrogel system as a skeleton structure between valve interstitial cells; and culturing the engineered heart valve tissue strip by using a calcification induction culture solution, so that the valve tissue generates a calcification phenotype. The model provided by the invention can generate a valve calcification phenotype which is similar to that after human heart valve calcification and is represented by valve interstitial cell activation, extracellular matrix remodeling such as collagen mass secretion and calcium deposition region generation. The model provided by the invention is low in cost, can be produced in batches, meets the research on the pathogenesis of extracorporeal valve calcification, and makes up for the dilemma that no artificial valve calcification model is available for drug research and development at present.

The invention discloses a steady-state leakage and forward flow testing device for a heart valve, and relates to the technical field of medical instrument inspection. The device comprises a reservoir, a pipeline, and a driving device, a regulating valve, a front-end flow meter, a front-end valve mounting channel and a rear-end valve mounting channel which are sequentially mounted on the pipeline, and the two ends of the pipeline are communicated with the reservoir. The heating and temperature control system ensures that the liquid temperature meets the requirement of a new edition standard, the valve installation channel with the inner diameter of 70 mm is suitable for a large-size mitral valve, and differential pressure sensor interfaces are arranged in front of and behind the valve ring of the artificial heart valve, so that the requirement of the new standard for the position of a sensor is met; according to the device, flexible selection of pressure values under different blood pressure states is achieved by adjusting the rotating speed of a driving device (a magnetic pump), accurate measurement and automation of the leakage amount are achieved through a high-precision flow meter, and the whole design aims at improving the accuracy and repeatability of testing and ensuring the quality and safety of an artificial heart valve.

Disclosed herein are a high-molecular artificial heart valve and a preparation method therefor, relating to the technical field of medical instruments. The high-molecular artificial heart valve comprises a frame, a skirt arranged on the surface of the frame, and valve leaflets bonded with the skirt. The preparation method therefor comprises the following steps: after the skirt is prepared on the frame, arranging a part of the valve leaflets on the surface of at least a part of the edge of the skirt, or connecting the edges of the valve leaflets with the at least a part of the skirt, and then bonding the valve leaflets with the edge of the skirt by means of interface microtreatment. The interface microtreatment is achieved by means of a polymer solution that bonds the valve leaflets with the edge of the skirt or by utilizing thermal bonding between the valve leaflets and the edge of the skirt. The valve prepared by the method has the advantages of uniform structure and high strength, effectively improving the production quality of the valve.

The invention discloses a method for promoting endothelialization of a heart valve and an artificial heart valve.The method is characterized in that circular DNA is modified on the surface of a decellularized valve (DHV), DNA hydrogel of targeted thrombin is obtained on the surface of the DHV through rolling circle amplification, the DNA hydrogel plays a role of a heme catcher while playing a role of the heme catcher, and heme is recruited from blood; heme is further converted into biliverdin (BV) through heme oxygenase (HO1) loaded in DNA, so that continuous production of biliverdin is ensured, anti-inflammatory immune regulation and active oxygen removal are promoted, a regenerative immune microenvironment is created, and endothelialization of the valve is promoted.

The invention relates to an artificial heart valve and a transcatheter heart valve replacement system.The artificial heart valve comprises a valve support and an outer skirt part, the valve support is provided with an inflow end and an outflow end, and the valve support is sequentially provided with a plurality of grid sets arranged in the circumferential direction from the outflow end to the inflow end; wherein the grid group closest to the inflow end is suitable for being matched with the position below the annulus plane, and the size of a net opening of at least one non-end grid group matched with the annulus plane is larger than that of a net opening of at least one axially adjacent grid group; the outer skirt part covers the outer surface of the valve stent, the outer skirt part at least covers the two adjacent grid groups close to the inflow end, and the position, close to the inflow end, of the outer skirt part is configured to be of a structure with the thickness gradually increased in the direction from the outflow end to the inflow end.

The invention provides an artificial heart valve thrombus risk assessment method and device. The thrombus risk assessment method for the artificial heart valve comprises the following steps: acquiring a physiological scene after the artificial heart is implanted into the artificial valve through a resistance characteristic parameter and an elastic expansion characteristic parameter; starting a pulsating pump to output a pulsating flow medium to the artificial heart in a physiological scene; capturing the motion trail of the fluorescent particles through a high-speed camera and obtaining the original data of the blood flow velocity at the downstream of the artificial valve; acquiring a fluid mechanics simulation parameter group according to the blood flow velocity original data; and inputting a pre-trained valvular thrombus random forest classifier according to the fluid mechanics simulation parameter group, and outputting a thrombus risk probability graph in the physiological scene. According to the method, the fluid mechanics simulation parameter group is calculated based on the instantaneous velocity vector field captured by the PIV and the space-time distribution information, the two-dimensional / three-dimensional thrombus risk probability graph is generated through the random forest classifier, the high-risk point coordinates are marked, and the thrombus probability and the thrombus position are accurately predicted.

The utility model discloses a combined type artificial heart valve which comprises a fixing assembly and a valve assembly, a fixing ring is arranged on the inner side face of the fixing assembly, the valve assembly is arranged in the fixing assembly through the fixing ring, and a valve piece in the valve assembly swings to achieve opening and closing of a simulated heart valve. The valve assembly comprises a valve ring and a valve piece rotationally arranged in the valve ring, and the valve ring and the fixing ring are detachably installed. By designing the combined artificial heart valve, the valve leaflet assembly and the fixing assembly which are detachably assembled, under the condition that the valve leaflet assembly needs to be replaced due to mechanical failure of the valve leaflet or thrombus generation, opening and closing of the valve leaflet are affected, only the valve leaflet assembly needs to be replaced, the fixing assembly sutured with the human heart does not need to be disassembled, and the human heart tissue is not damaged; and the surgical risk and difficulty are greatly reduced.

An anchoring device (100, 200, 300) for prosthetic heart valve (400) and a prosthetic heart valve system. The prosthetic heart valve system includes an anchoring device (100, 200, 300) and a prosthetic heart valve (400). The anchoring device (100, 200, 300) includes an anchoring section (110, 210, 310) and a supporting section (120, 220, 320) that are axially connected to each other. The anchoring section (110, 210, 310) has an annular first cavity (111, 211, 311) configured to accommodate a prosthetic heart valve (400). The supporting section (120, 220, 320) is arranged on one side of the anchoring section (110, 210, 310) along the axial direction thereof. The supporting section (120, 220, 320) includes at least two elastic wires (121, 221, 321) arranged sequentially on the circumference of the anchoring section (110, 210, 310). Each elastic wire (121, 221, 321) has an end connected to the anchoring section (110, 210, 310), and a further end extending in a direction away from the anchoring section (110, 210, 310). The anchoring device (100, 200, 300) can utilize the structure of the predetermined chamber to anchor the prosthetic heart valve (400) without crossing the native valve annulus during implantation, thereby effectively preventing the occurrence of paravalvular leakage after the prosthetic heart valve (400) is implanted.

The invention discloses a self-repairing acrylate dielectric material based on a dual-mode network as well as a preparation method and application of the self-repairing acrylate dielectric material based on the dual-mode network. According to the material, dynamic covalent chemistry and a synergistic effect of a dual-mode network structure are utilized, a long-chain flexible cross-linking agent and a short-chain chain extender containing dynamic thiocarbamate bonds are adopted, and the self-repairing acrylate dielectric material based on the dual-mode network is prepared. Meanwhile, the proportion of the multifunctional micromolecule TMPTMA or PET4A is optimized, and performance balance and self-repairing are achieved. In the preparation process, click reaction curing is initiated through ultraviolet light, the process is simple, and the cost is low. The tensile strength is 0.3-0.6 MPa, the elongation at break is 350%, the dielectric constant at 1kHz is 7-9, the dielectric loss is 0.047-0.067, and the mechanical property can be completely recovered within 30 minutes at the temperature of 100 DEG C. The device is suitable for bionic flapping wing aircraft muscle systems, muscle-like drivers, repairable artificial heart valves and the like, damage is repaired through dynamic key recombination, the reliability of the device is improved, and the service life of the device is prolonged.

The invention provides a mitral valve replacement system in the technical field of medical instruments, and the mitral valve replacement system comprises a valve stent, a fixing ring and a shearing part, the fixing ring is arranged around the end face of the valve stent, and the shearing part is oppositely arranged on one side of the valve stent. The fixing ring surrounds the groove in the end face of the valve support to limit the moving direction of the valve support, so that the valve support is stably located at the native mitral valve ring, and the butterfly buckle is arranged on the valve support to buckle and clamp the native mitral valve leaflet. The fixing ring is tied and hooped at the groove in the end face of the valve support of the artificial heart valve, so that the artificial heart valve is stably positioned at the original mitral valve annulus, displacement of the artificial heart valve caused by external force factors such as blood flow impact force is prevented, and then the perivalvular leakage problem caused by displacement is avoided; the native mitral valve anterior leaflet is cut open through the cutting part, and then the cut native mitral valve anterior leaflet is buckled and clamped through the butterfly buckle, so that blood flowing through the native mitral valve anterior leaflet smoothly circulates, and the problem that the left ventricular outflow tract is obstructed is solved.

The invention discloses an artificial heart valve control handle which comprises a first handle body and a second handle body which are in sliding positioning fit, and each handle body comprises a supporting component and a driving mechanism arranged on the supporting component. A supporting component in the first handle comprises a first supporting body and two supporting rods which are fixedly connected to the first supporting body and extend towards the near end, the two supporting rods are arranged side by side, and positioning teeth are arranged on the opposite sides of the two supporting rods. A supporting component in the second handle comprises a second supporting body, guide holes are formed in the second supporting body, the two supporting rods extend into the corresponding guide holes in a sliding mode, and the second handle is further provided with a sliding locking mechanism which is matched with the positioning teeth to limit the relative position of the first handle and the second handle. The supporting rod serves as a connecting component between the second handle and the first handle and is further provided with positioning teeth used for being matched with the sliding locking mechanism to control the position of the second handle relative to the first handle, operation of the control handle is met, and meanwhile the structure of the control handle is simplified.

The invention relates to a steady-state flow testing machine for an artificial heart valve. The steady-state flow testing machine comprises a forward flow testing loop formed by sequentially connecting a liquid storage system, a circulating pump, a rectifying system, a testing clamping system and a forward flow return pipe, and an anti-leakage return pipe connected between the testing clamping system and the liquid storage system, the test clamping system comprises a front-end fixed cavity, a rear-end movable cavity and a valve carrier mounted at the connecting end of the front-end fixed cavity and the rear-end movable cavity, and pressure sensors are mounted on the front-end fixed cavity and the rear-end movable cavity respectively; and the forward flow return pipe and the reverse leakage return pipe are respectively provided with a flow sensor. Forward flow and reverse leakage are detected through independent flow sensors respectively, meanwhile, the precision of forward flow testing and reverse leakage testing is guaranteed, and the accuracy of the testing result is improved.

The invention relates to a high-molecular artificial heart valve and a preparation method thereof. The high-molecular artificial heart valve is composed of a specially-designed valve support and high-molecular valve leaflets. The inflow end of the valve support extends outwards in the radial direction relative to the outflow end to form a circumference, through holes are distributed in the circumference, a plurality of arc-shaped sections are formed at the outflow end and used for attachment of valve leaflets, reinforcing ribs are arranged on the outer walls of the arc-shaped sections, arc-shaped grooves are formed in the surfaces of the arc-shaped sections, and convex stand columns are arranged at the junctions of the adjacent valve leaflets at the top of the outflow end between the adjacent arc-shaped sections. The preparation method adopts a step-by-step dip-coating curing process and comprises the steps of pre-dip-coating, formal dip-coating and annealing heat treatment. By optimizing the structural design and preparation process of the valve stent, the combination firmness of the valve stent and the high-molecular valve leaflet is remarkably improved, the pore defect between the valve stent and the high-molecular valve leaflet is effectively reduced, and the internal stress of the valve leaflet under the blood flow load is reduced, so that the service life of the high-molecular valve is greatly prolonged; and the reliability and the durability in practical application are improved.

The invention provides a preparation method of a polymer artificial heart valve composite material, which comprises the following steps: immersing a fabric with a first polymer layer on the surface into a poor solvent, and paving the fabric on a substrate, so that when the first polymer layer is in contact with a second polymer solution, the first polymer layer is only slightly dissolved; forming a coating formed by embedding the first polymer layer and the second polymer layer on the surface of the fabric under the action that the poor solvent prevents the second polymer solution from entering the fabric; meanwhile, after the fabric is immersed in the poor solvent, the adsorption of the fabric to the second polymer solution is reduced, so that the fabric is kept flat in the composite material, the internal structure of the composite material is uniform, and the stability of the composite material is enhanced. By means of the mode, the polymer artificial heart valve composite material which is uniform in internal structure and smooth and flat in surface is prepared.

The invention provides an artificial heart valve device, and relates to the technical field of heart surgeries, valve leaflets are fixedly mounted on a supporting assembly, and the inner edge of a suture ring is used for being sutured and fixed with the supporting assembly and providing support for the valve leaflets; the outer edge (second connecting surface) of the suture ring is sutured with a tissue ring, so that the valve leaflet and the supporting assembly are fixed on the tissue ring; the suture ring is a non-planar flexible ring which is continuously arranged, the inner edge (a first connecting surface) and the outer edge of the suture ring have a size difference in the radial direction and have an axial fall in the axial direction, and the surface of the suture ring is a spatial curved surface and is of a skirt-shaped size change structure, so that the outer edge of the suture ring can be subjected to radial size change; the circumferential size of the outer edge is adaptively and flexibly deformed so as to be matched with tissue rings of different sizes within a certain range, and the shape and size adaptation range of the suture ring is expanded.

1. Name of the product in this design: Transcatheter replacement of mitral valve. 2. Purpose of this design: for artificial heart valve replacement in the medical field. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The present invention belongs to the technical field of artificial heart valves, and particularly relates to a method for forming a frame of an artificial heart valve, a planar forming machine and a mold. The method for forming a frame of an artificial heart valve, the planar forming machine and the mold of the present invention are provided with a plurality of convex push blocks and arc-shaped push blocks that can move independently, and according to the forming curve of the wire, the mold closing directions of the respective push blocks are designed, which can avoid and overcome the technical problem in the prior art that during the planar forming process, when the upper and lower molds provide a relatively large vertical force, the sliding property of the wire in the horizontal direction is not good, resulting in incomplete mold closing and failure to achieve the expected shaping effect; moreover, due to the unique design of the mold closing direction, the external force applied by the push block on the wire is small, scratches on the wire are not likely to occur, and the appearance of the finished product will not be affected; the planar forming machine for the frame of the artificial heart valve can realize continuous automated production of planar forming, so as to improve production efficiency.

The application discloses a heart valve device and relates to the technical field of artificial heart valves, which comprises an outer valve frame and a valve leaflet assembly connected to the inside of the outer valve frame, and the outer valve frame is a ring-shaped grid frame; the outer valve frame comprises an inflow side grid frame and an outflow side grid frame arranged in sequence from an inflow end to an outflow end, and the inflow side grid frame and the outflow side grid frame form an annular recess for clamping a native valve ring on the outer periphery of the outer valve frame; the outflow side grid frame comprises a plurality of groups of grid support units connected in sequence along the circumferential direction and enclosed into a ring, and the grid support unit comprises an outer convex grid support and an inner concave grid support, and the outer surface of the inner concave grid support is arranged in a concave manner relative to the outer surface of the outer convex grid support. In this way, the anterior leaflet of the original mitral valve can be attached to the inner concave grid support, the extrusion of the outer valve frame on the anterior leaflet is reduced, the anterior leaflet is prevented from being extruded to the left ventricular outflow tract by the outer valve frame, and the outflow area of the left ventricular outflow tract is prevented from being reduced to cause obstruction.

Disclosed in the present application are an artificial heart valve, an interventional system, and a position registration method for an artificial heart valve. The artificial heart valve comprises: a stent, which is of a cylindrical structure and has a spatially axial direction, the interior of the cylindrical structure being a blood flow channel, and the stent being radially deformable so as to switch between a delivery state in which the stent is radially compressed and a deployed state in which the stent is radially deployed; valve leaflets, which are connected to the stent to control the blood flow channel; and a first radiopaque marker, which is connected to the stent. At the reference angle of viewing of the stent, when the stent rotates around its own axis, the distance between the projection position of the first radiopaque marker and the axis of the stent changes correspondingly.

The utility model discloses a machining die for an artificial heart valve support, which belongs to the technical field of production and machining of medical instruments, and comprises a support main body and a die-casting main body, the die-casting main body comprises at least two hold-down units, each hold-down unit comprises a first hold-down component and a second hold-down component, and the first hold-down component and the second hold-down component are arranged in the axial direction of the support main body. The first pressing and holding assembly and the second pressing and holding assembly are detachably connected. The first pressing assembly comprises a first pressing piece and a fixed anchor pressing piece, the fixed anchor pressing piece is arranged on the outer wall of the first pressing piece, the side, close to the fixed anchor pressing piece, of the first pressing piece is provided with a first protruding structure and a positioning groove, the first protruding structure is arranged in the positioning groove, and the fixed anchor pressing piece is provided with a second protruding structure corresponding to the first protruding structure. The inner wall and the outer wall of the fixing anchor are extruded and shaped through the first protruding structure and the second protruding structure respectively, so that the main body of the artificial heart valve stent and the fixing anchor are simultaneously machined at a time through the machining die, and the machining production efficiency is improved.

The present invention provides a valve delivery device and its delivery system, comprising: a catheter part, the catheter part is provided with a first end for being delivered into the human body and a second end for providing operations, and includes an inner tube and an intermediate tube sleeved outside the inner tube; a housing part, the housing part is provided with a first housing, an outer tube and a second housing, the first end of the outer tube is fixedly communicated with the first housing, and the second end of the outer tube is fixedly communicated with the second housing; an anchoring member, the anchoring member is fixed at the first end of the intermediate tube and fixedly carries a stent for an artificial heart valve; a first control structure arranged at the second end of the catheter part and used for controlling the relative sliding of the intermediate tube and the outer tube; the housing part is sleeved on the catheter part. The present invention is used to deliver an artificial heart valve to the position of the native valve and replace the diseased valve, and can perform circumferential control, thereby improving the delivery effect.

The present application belongs to the technical field of interventional medical devices, and provides an artificial valve prosthesis delivery device, including a handheld portion, a valve prosthesis accommodating component connected to the handheld portion, the valve prosthesis accommodating component including a socketable distal end portion and a proximal end portion, and a valve carrier arranged in an accommodating space formed after the distal end portion and the proximal end portion are socketed; the handheld portion is provided with a first driving mechanism for adjusting the relative position distance between the distal end portion and the valve carrier, and a second driving mechanism for adjusting the relative position distance between the proximal end portion and the valve carrier. In this solution, when an artificial heart valve is implanted, relative movement can exist between the valve carrier and the distal end portion and the proximal end portion on the delivery device, so that the valve carrier can be easily adjusted when releasing the artificial mitral valve, thereby reducing the difficulty of the operation.

The invention discloses an intelligent artificial heart valve integrated with pressure sensing, which comprises an implantation end and a body surface relay patch, the implantation end comprises a stent valve main body, a valve crossing pressure sensor pair, a microelectronic module and a flexible circuit, and the stent valve main body comprises a valve frame and a valve leaflet. The transvalvular pressure sensor pair comprises a first pressure sensor fixed to the ventricular proximal side of the stent valve body and a second pressure sensor fixed to the ventricular distal side of the stent valve body, leads of the pressure sensors are electrically connected with the microelectronic module through a flexible circuit, and the flexible circuit comprises a planar spiral coil; the plane spiral coil is electrically connected with the microelectronic module, the body surface relay patch comprises an external read-write coil, the external read-write coil transmits energy to the plane spiral coil, and the cross-lobe pressure sensor sends sensed data to the external read-write coil through the plane spiral coil. According to the invention, abnormal early warning can be realized, the treatment lagging is shortened, and the complication cost is reduced.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.