172 results about "Artificial heart valve" patented technology

The invention discloses an artificial heart valve near-physiological pulsation fluid external evaluation device and method, and relates to the technical field of heart valve testing.The artificial heart valve near-physiological pulsation fluid external evaluation device comprises a supporting frame, a driving unit, a tested valve installation unit and an artery and peripheral loop unit, the driving unit provides power for liquid flowing, and the tested valve installation unit is used for fixing an artificial heart valve; and a liquid volume assembly and a resistance assembly of the artery and peripheral loop unit can simulate the compliance and resistance of aorta blood vessels and peripheral artery blood vessels, so that the pressure waveform simulation of the systemic circulation loop is more accurate. On the basis of the air cavity, the elastic corrugated pipes with different frequency responses are arranged, the compliance and rebound resilience of the aorta are simulated, a device for rapidly replacing the tested valve is designed, and the mechanical property of the simulated human body aorta is adjusted by adjusting the parameters such as the output frequency and the vibration amplitude of the driving unit; real pressure and flow waveforms under different physiological / pathological conditions are simulated, and a more accurate and convenient detection environment is realized.

The invention relates to an artificial heart valve and a transcatheter heart valve replacement system.The artificial heart valve comprises a valve support and an outer skirt part, the valve support is provided with an inflow end and an outflow end, and the valve support is sequentially provided with a plurality of grid sets arranged in the circumferential direction from the outflow end to the inflow end; wherein the grid group closest to the inflow end is suitable for being matched with the position below the annulus plane, and the size of a net opening of at least one non-end grid group matched with the annulus plane is larger than that of a net opening of at least one axially adjacent grid group; the outer skirt part covers the outer surface of the valve stent, the outer skirt part at least covers the two adjacent grid groups close to the inflow end, and the position, close to the inflow end, of the outer skirt part is configured to be of a structure with the thickness gradually increased in the direction from the outflow end to the inflow end.

The invention provides an artificial heart valve thrombus risk assessment method and device. The thrombus risk assessment method for the artificial heart valve comprises the following steps: acquiring a physiological scene after the artificial heart is implanted into the artificial valve through a resistance characteristic parameter and an elastic expansion characteristic parameter; starting a pulsating pump to output a pulsating flow medium to the artificial heart in a physiological scene; capturing the motion trail of the fluorescent particles through a high-speed camera and obtaining the original data of the blood flow velocity at the downstream of the artificial valve; acquiring a fluid mechanics simulation parameter group according to the blood flow velocity original data; and inputting a pre-trained valvular thrombus random forest classifier according to the fluid mechanics simulation parameter group, and outputting a thrombus risk probability graph in the physiological scene. According to the method, the fluid mechanics simulation parameter group is calculated based on the instantaneous velocity vector field captured by the PIV and the space-time distribution information, the two-dimensional / three-dimensional thrombus risk probability graph is generated through the random forest classifier, the high-risk point coordinates are marked, and the thrombus probability and the thrombus position are accurately predicted.

The invention relates to a high-molecular artificial heart valve and a preparation method thereof. The high-molecular artificial heart valve is composed of a specially-designed valve support and high-molecular valve leaflets. The inflow end of the valve support extends outwards in the radial direction relative to the outflow end to form a circumference, through holes are distributed in the circumference, a plurality of arc-shaped sections are formed at the outflow end and used for attachment of valve leaflets, reinforcing ribs are arranged on the outer walls of the arc-shaped sections, arc-shaped grooves are formed in the surfaces of the arc-shaped sections, and convex stand columns are arranged at the junctions of the adjacent valve leaflets at the top of the outflow end between the adjacent arc-shaped sections. The preparation method adopts a step-by-step dip-coating curing process and comprises the steps of pre-dip-coating, formal dip-coating and annealing heat treatment. By optimizing the structural design and preparation process of the valve stent, the combination firmness of the valve stent and the high-molecular valve leaflet is remarkably improved, the pore defect between the valve stent and the high-molecular valve leaflet is effectively reduced, and the internal stress of the valve leaflet under the blood flow load is reduced, so that the service life of the high-molecular valve is greatly prolonged; and the reliability and the durability in practical application are improved.

The present invention belongs to the technical field of artificial heart valves, and particularly relates to a method for forming a frame of an artificial heart valve, a planar forming machine and a mold. The method for forming a frame of an artificial heart valve, the planar forming machine and the mold of the present invention are provided with a plurality of convex push blocks and arc-shaped push blocks that can move independently, and according to the forming curve of the wire, the mold closing directions of the respective push blocks are designed, which can avoid and overcome the technical problem in the prior art that during the planar forming process, when the upper and lower molds provide a relatively large vertical force, the sliding property of the wire in the horizontal direction is not good, resulting in incomplete mold closing and failure to achieve the expected shaping effect; moreover, due to the unique design of the mold closing direction, the external force applied by the push block on the wire is small, scratches on the wire are not likely to occur, and the appearance of the finished product will not be affected; the planar forming machine for the frame of the artificial heart valve can realize continuous automated production of planar forming, so as to improve production efficiency.

The application discloses a heart valve device and relates to the technical field of artificial heart valves, which comprises an outer valve frame and a valve leaflet assembly connected to the inside of the outer valve frame, and the outer valve frame is a ring-shaped grid frame; the outer valve frame comprises an inflow side grid frame and an outflow side grid frame arranged in sequence from an inflow end to an outflow end, and the inflow side grid frame and the outflow side grid frame form an annular recess for clamping a native valve ring on the outer periphery of the outer valve frame; the outflow side grid frame comprises a plurality of groups of grid support units connected in sequence along the circumferential direction and enclosed into a ring, and the grid support unit comprises an outer convex grid support and an inner concave grid support, and the outer surface of the inner concave grid support is arranged in a concave manner relative to the outer surface of the outer convex grid support. In this way, the anterior leaflet of the original mitral valve can be attached to the inner concave grid support, the extrusion of the outer valve frame on the anterior leaflet is reduced, the anterior leaflet is prevented from being extruded to the left ventricular outflow tract by the outer valve frame, and the outflow area of the left ventricular outflow tract is prevented from being reduced to cause obstruction.

Disclosed in the present application are an artificial heart valve, an interventional system, and a position registration method for an artificial heart valve. The artificial heart valve comprises: a stent, which is of a cylindrical structure and has a spatially axial direction, the interior of the cylindrical structure being a blood flow channel, and the stent being radially deformable so as to switch between a delivery state in which the stent is radially compressed and a deployed state in which the stent is radially deployed; valve leaflets, which are connected to the stent to control the blood flow channel; and a first radiopaque marker, which is connected to the stent. At the reference angle of viewing of the stent, when the stent rotates around its own axis, the distance between the projection position of the first radiopaque marker and the axis of the stent changes correspondingly.

The utility model discloses a machining die for an artificial heart valve support, which belongs to the technical field of production and machining of medical instruments, and comprises a support main body and a die-casting main body, the die-casting main body comprises at least two hold-down units, each hold-down unit comprises a first hold-down component and a second hold-down component, and the first hold-down component and the second hold-down component are arranged in the axial direction of the support main body. The first pressing and holding assembly and the second pressing and holding assembly are detachably connected. The first pressing assembly comprises a first pressing piece and a fixed anchor pressing piece, the fixed anchor pressing piece is arranged on the outer wall of the first pressing piece, the side, close to the fixed anchor pressing piece, of the first pressing piece is provided with a first protruding structure and a positioning groove, the first protruding structure is arranged in the positioning groove, and the fixed anchor pressing piece is provided with a second protruding structure corresponding to the first protruding structure. The inner wall and the outer wall of the fixing anchor are extruded and shaped through the first protruding structure and the second protruding structure respectively, so that the main body of the artificial heart valve stent and the fixing anchor are simultaneously machined at a time through the machining die, and the machining production efficiency is improved.

The invention discloses an intelligent artificial heart valve integrated with pressure sensing, which comprises an implantation end and a body surface relay patch, the implantation end comprises a stent valve main body, a valve crossing pressure sensor pair, a microelectronic module and a flexible circuit, and the stent valve main body comprises a valve frame and a valve leaflet. The transvalvular pressure sensor pair comprises a first pressure sensor fixed to the ventricular proximal side of the stent valve body and a second pressure sensor fixed to the ventricular distal side of the stent valve body, leads of the pressure sensors are electrically connected with the microelectronic module through a flexible circuit, and the flexible circuit comprises a planar spiral coil; the plane spiral coil is electrically connected with the microelectronic module, the body surface relay patch comprises an external read-write coil, the external read-write coil transmits energy to the plane spiral coil, and the cross-lobe pressure sensor sends sensed data to the external read-write coil through the plane spiral coil. According to the invention, abnormal early warning can be realized, the treatment lagging is shortened, and the complication cost is reduced.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.

The present disclosure discloses a matching method and device of a heart valve and an electronic device. The method comprises: determining a plurality of target planes in a heart according to an anatomical structure image of the heart; determining a structural feature of the heart in each plane according to the anatomical structure image; determining a junction point in each target plane of the plurality of target planes according to the structural feature, wherein the junction point is a point at a junction edge between any two adjacent leaflets of the heart valve of the heart, and the junction edge is a connecting position between any two adjacent leaflets; determining a first push-away range corresponding to each target plane according to the junction point and the structural feature of the heart; determining a second push-away range corresponding to the heart valve according to the first push-away range corresponding to each target plane; and determining an artificial heart valve matched with the heart valve according to the second push-away range. The present disclosure solves the technical problem that the accuracy cannot be guaranteed due to the determination of the heart valve according to experience in the related art.

The utility model relates to a valve frame and an artificial heart valve. The valve frame can be switched between a radial compression structure and a radial expansion structure; each of an inflow row grid, an outflow row grid and a middle row grid of the valve frame comprises two rows of wave rods which are oppositely arranged and connected with each other, each row of wave rods comprises a plurality of supporting rods, and the opposite ends of every two adjacent supporting rods are connected at a joint part; each joint part comprises a solid part and a vacant part radially penetrating through the solid part, the opposite ends of the two adjacent supporting rods are smoothly connected with the solid part on the two sides of the vacant part, the vacant part is also in a smooth shape, and an opening of the vacant part corresponding to the wave crest of the wave rod faces the wave trough in the axial direction; the opening of the vacant part corresponding to the wave trough of the wave rod faces the wave crest in the axial direction; the joint part is used for helping each grid to uniformly deform in the structure conversion process of the valve frame; the width of the solid part is larger than or equal to the sum of two times of the width of the supporting rod and the width of the vacant part. The heart valve prosthesis comprises the valve frame, a covering film and at least two artificial valve leaflets capable of being opened and closed oppositely.

The invention discloses a telescopic and movable heart valve prosthesis stent and a control system thereof, and the telescopic and movable heart valve prosthesis stent comprises the telescopic and movable heart valve prosthesis stent which is provided with a concave honeycomb unit structure; the strain sensing module is integrated at the stressed part of the concave honeycomb unit and is used for acquiring strain data of each honeycomb unit in real time; the data transmission module is connected with the strain sensing module and transmits the strain data to the control module; the control module is in communication connection with the data transmission module and comprises the steps of pre-storing a mapping model and updating and / or storing a corresponding relation of compression force-strain-radial shrinkage amount; the PID control module is used for calculating a real-time compression force adjusting instruction according to the deviation between the real-time strain data and the target strain; and the force control execution module is arranged at the front end of the conveying conduit, is in communication connection with the control module, and is used for applying or reducing local compression force to the corresponding honeycomb unit according to the compression force adjustment instruction. The invention adapts to the growth needs of patients, and reduces the surgical risk.

The invention discloses an artificial heart valve and a processing method. The heart valve prosthesis comprises a support and a plurality of valve leaflets connected to the support, the support is of a cylindrical structure, a blood flow channel is formed in the support, each valve leaflet comprises a body, the body has the transverse direction and the longitudinal direction which are opposite in the flattened state, and the outer edge of the body comprises a free edge and a fixed edge which are distributed on the two opposite sides in the longitudinal direction; the valve leaflets are fixed to the support through the fixing edges of the valve leaflets, and the free edges of the valve leaflets are matched with one another to control a blood flow channel in the artificial heart valve. The lug pieces are arranged on the two transverse opposite sides of the body, the free edges and the fixed edges of the lug pieces intersect at the corresponding sides, and each lug piece is provided with a first bending part which is bent towards the transverse inner side of the body from the combination part of the lug piece and the body and is attached to the body to form a combination part of a double-layer structure; and the second bending part is bent from the tail end of the first bending part to the transverse outer side of the body. By improving the valve leaflet structure and the suture method, the sealing effect and safety of the valve leaflet are improved.

A method and an assembly for attaching a radiopaque marker to an attachment member of an artificial valve are disclosed. As an example, an artificial heart valve can include a frame including struts forming cells of the frame, at least one commissure comprising an attachment member and commissure tabs of two adjacent valve leaflets coupled thereto, an attachment member disposed across the cells of the frame and attached to the struts defining the cells, and a radiopaque marker suspended within the cell and suspended relative to the attachment member by suture threads. The suture threads extend from a first portion of the attachment member, through one or more openings of the marker, to a second portion of the attachment member, and the suture threads form two knots at the second portion on opposite sides of the marker such that the suture threads form an X-pattern that does not cross through the marker and across the attachment member.

The application discloses a valve holder, an assembly and a valve loading system for delivering a prosthetic heart valve, wherein the valve holder for delivering a prosthetic heart valve comprises a connecting seat and at least one holding arm distributed on the outer periphery of the connecting seat, the at least one holding arm has a positioning structure at the distal end thereof, which matches the outflow side of the prosthetic heart valve; the at least one holding arm is provided with a frame for placing a binding wire for binding the prosthetic heart valve, the frame has a wire passing path and a wire cutting port corresponding to the wire passing path, and the wire passing path allows a wire segment of the binding wire extending along the wire passing path to be suspended. The optimized arrangement of the valve holder, the assembly and the system of the application avoids the interference of the valve holder with the holding, positioning and releasing process of the prosthetic heart valve, meanwhile, provides a structural basis for the arrangement of the surrounding matching components, optimizes the operation experience of medical staff and improves the treatment effect.

Systems and methods for reducing vibrations perceived by a human due to an artificial heart valve include a vest that is wearable around a torso of the human, a plurality of sensors mounted to the vest, a plurality of vibration-generating actuators mounted to the vest, and a controller. The plurality of sensors detects vibrations in the human generated by the artificial heart valve. The controller is operable to receive signals representing the detected vibrations from the plurality of sensors, and is operable to produce anti-vibration signals that substantially attenuate the detected vibrations. A first sensor of the plurality of sensors is located near a first vibration-generating actuator of the plurality of vibration-generating actuators to form a sensor / actuator set. In the sensor / actuator set, the anti-vibration signals generated by the controller for the first vibration-generating actuator correspond to the vibrations detected by the first sensor.

This invention discloses a novel valve stent and artificial heart valve, belonging to the field of medical device technology. The valve stent has a hollow, symmetrical, mesh-like tubular structure, with a first layer of hexagonal mesh groups, a second layer of polygonal mesh groups, and a third layer of polygonal mesh groups arranged sequentially from the outflow end to the inflow end. The stent has a small overall mesh count and symmetrical structure, resulting in uniform deformation during compression and expansion. It exhibits excellent radial support and minimal expansion rebound, significantly reducing the risk of paravalvular leakage. While maintaining radial support, this invention can reduce the stent strut width to 0.2–0.4 mm, and the minimum outer diameter of the valve after compression can reach 2.5–4.5 mm. Simultaneously, the overall length change during stent compression and expansion is minimal, greatly improving the smoothness of vascular delivery and the accuracy of valve implantation positioning. This meets the clinical needs of transcatheter aortic valve replacement surgery, enhancing the safety and effectiveness of artificial heart valve implantation.

A medical device that is adapted for excising a valve leaflet portion of a valve leaflet from a heart valve includes an elongate shaft including a distal region and an inflatable balloon that is secured to the distal region and that is adapted to extend through the heart valve. The inflatable balloon has an outer surface and includes a deflated configuration and an inflated configuration. An electrocautery electrode is disposed relative to the inflatable balloon such that the electrocautery electrode is positioned to excise the valve leaflet portion when RF energy is applied to the electrocautery electrode and the inflatable balloon is in the inflated configuration. In some cases, the heart valve includes an artificial heart valve. In some cases, the valve leaflet includes an artificial valve leaflet.

The application discloses an artificial heart valve device, an interventional instrument conveying assembly and a control handle, wherein the interventional instrument conveying assembly comprises a lock seat provided with a locking part; a lock piece is located at the distal end side of the lock seat; the lock piece is movable relative to the lock seat and has a release position which is separated from the locking part and a locking position which is inserted into the locking part; a pull wire assembly has a working end at the distal end, and the working end is wound to the interventional instrument in a loaded state and cooperates with the lock piece, wherein the lock piece restricts the pull wire in the locking position and releases the pull wire in the release position. The technical scheme disclosed by the application realizes the whole process control of the artificial heart valve stent through the guide part, especially the threading ring, meanwhile, the setting mode and the extension shape of the guide part can reduce the influence of the self-expanding characteristics of the artificial heart valve stent on the recovery of the artificial heart valve stent. The operation experience of medical staff is improved, and the treatment effect is improved.

The present invention relates to an implantable artificial device, such as an artificial heart valve, and to a mounting configuration and method for attaching a soft component, such as a valve leaflet or skirt, to the frame of such an artificial valve. [Solution] The valve leaflets are connected to the struts of the frame via primary sutures, which are passed in an in-and-out pattern along the cusp end portion of the valve leaflets, and the secondary sutures are passed around the struts through the primary sutures and have a plurality of self-tightening structures configured to contract on the struts under tension.

This disclosure relates to an artificial heart valve for replacing a natural heart valve, comprising: an annular stent including: a mesh structure serving as a circumferential sidewall of the stent; and a leaflet structure, each leaflet being attached to the stent and having a first portion disposed within the stent and a second portion rolled up to the proximal peripheral side of the stent. As the heart grows, the stent can be expanded after the artificial heart valve is anchored to the heart, thereby allowing the artificial heart valve to function in different states without replacement. The edge end of the second portion of each leaflet is connected to the stent at a location between the distal and proximal ends of the stent, but not fixed to the proximal end of the stent. In at least one state, the size of each leaflet exceeds the fit size of the stent in that state, and each leaflet has a redundant portion that hangs freely from the distal to the proximal end to a location away from the stent, thereby allowing the leaflet to be sized away from the stent to form a more functional valve.

The application discloses a heart valve releasing mechanism, a releasing catheter and an artificial heart valve conveying system. The heart valve releasing mechanism is used for clamping and releasing an artificial heart valve and comprises a clamping jaw, a moving part and a clamping jaw. The clamping jaw comprises a first clamping arm and a second clamping arm which are arranged at intervals. The moving part has a moving space. At least a part of the first clamping arm and at least a part of the second clamping arm are movably arranged in the moving space. The clamping jaw has a clamping state and a releasing state. In the clamping state, at least a part of the artificial heart valve is clamped between the first clamping arm and the second clamping arm. In the releasing state, the distance between the first clamping arm and the second clamping arm is increased, and the artificial heart valve can be separated from the clamping jaw. The clamping jaw can be switched between the clamping state and the releasing state by moving the moving part relative to the clamping jaw. The releasing mechanism has simple structure and convenient operation, and can facilitate the assembly and disassembly of the artificial heart valve.

The present application relates to a kind of artificial heart valve stents and artificial heart valve.The artificial heart valve stent includes inner support and outer support.Inclination from inflow end to outflow end, first portion and second portion are included in sequence in inner support, the radial dimension of first portion is greater than the radial dimension of second portion, at least a portion of second portion is nested in outer support, and at least a portion of first portion extends to inflow end relative to outer support, and the portion of first portion extending to inflow end relative to outer support covers flow blocking film.The artificial heart valve includes the artificial heart valve stent and artificial valve leaflet fixedly connected in inner support.The artificial heart valve stent and artificial heart valve can reduce the risk of paravalvular leakage while being stably positioned in heart.

The present invention provides a valve stent and a usage method thereof for bicuspid aortic valve stenosis, comprising an ascending aorta contact area, a connecting body, a valve support area and a valve prosthesis suture part; the ascending aorta contact area is in an annular shape, a honeycomb-like structure formed by arranging and connecting a plurality of regular hexagons; the valve support area is in an elliptical annular shape, a grid structure formed by arranging and connecting a plurality of rhombuses. The present invention enhances the radial stiffness of the stent, thereby improving its radial support capacity; the valve support area is designed as an elliptical ring structure, and when implanting the artificial heart valve stent, the long-axis implantation angle of the valve stent is kept perpendicular to the long axis of the valve annulus, and by using the mutual coupling effect between the two, the cross-sectional shape of the expanded valve stent is finally circular, which improves the problem of poor expansion during the implantation of the valve stent and the elliptization after the valve stent is implanted, thereby reducing the occurrence of paravalvular leakage, with uniform stress and extended service life.

A device for treating a diseased native valve in a patient is provided, the device comprising: a frame structure; valve segments radially arranged within the frame structure, the valve segments including a plurality of leaflets; and a plurality of commissure attachment mechanisms coupling the leaflets to the frame structure, each commissure attachment mechanism extending radially inward from the outflow end of the frame structure to form a gap between an inner diameter of the outflow end and an outflow edge of the valve segment. Other embodiments and methods of use are also provided.

1. Name of the product in this design: Cardiac stent. 2. Purpose of this design: This design is used to maintain or connect to an artificial heart valve. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The invention discloses an antibacterial compound containing shellac nanoparticles and a preparation method of the antibacterial compound, and belongs to the technical field of medical materials. The antibacterial product is a polylactic acid-glycolic acid copolymer (PLGA) loaded shellac nanoparticle antibacterial coating or hyaluronic acid (HA) loaded shellac nanoparticle antibacterial gel. The coating and the gel prepared by the invention have excellent antibacterial performance and good biocompatibility, and the preparation method is relatively simple. The antibacterial coating can be applied to the surfaces of medical instruments such as intravascular stents, artificial heart valves, artificial blood pumps, artificial blood vessels, catheters and vein filters to improve the antibacterial performance of the medical instruments, and can also be applied to the surfaces of skin and mucosa to improve the antibacterial performance.