40 results about "Annuloplasty rings" patented technology

The invention relates in some aspects to a device for use in anchoring an implant, including anchors, sutures, implants, clips, tools, lassos, and methods of anchoring among other methods. Anchors as disclosed herein could be utilized to secure a coaptation assistance device, an annuloplasty ring, an artificial valve, cardiac patch, sensor, pacemaker, or other implants. The implant could be a mitral valve ring or artificial mitral valve in some embodiments.

An annuloplasty ring is disclosed. The annuloplasty ring includes an outer tube, a plurality of anchors, and at least one synthetic leaflet. The synthetic leaflets are in mechanical communication with the annuloplasty ring at a plurality of points. The outer tube includes a plurality of windows. The plurality of anchors are positioned inside the outer tube and about a perimeter of the outer tube. The plurality of anchors are configured to be emitted from the plurality of windows in order to anchor the annuloplasty ring to a heart valve of a patient.

An annuloplasty ring includes an elastic elongated core having first regions and second regions, wherein the first regions are more stretchable than the second regions and are adapted for positioning at the commissures of a target native heart valve. The first regions and the second regions may enable the annuloplasty ring to both re-establish coaptation of the leaflets of a diseased native heart valve and establish a seal around a prosthetic replacement heart to prevent paravalvular leakage after a “Valve In Ring Procedure”.

The invention relates in some aspects to a device for use in anchoring an implant, including anchors, sutures, implants, clips, tools, lassos, and methods of anchoring among other methods. Anchors as disclosed herein could be utilized to secure a coaptation assistance device, an annuloplasty ring, an artificial valve, cardiac patch, sensor, pacemaker, or other implants. The implant could be a mitral valve ring or artificial mitral valve in some embodiments.

This invention provides a bicuspid aortic valve implantable annuloplasty ring, comprising two symmetrically arranged semi-annular bodies. The two ends of the two semi-annular bodies are connected in a saddle shape by a connecting post, and the connecting post extends upward by a predetermined length, forming the highest point of the annuloplasty ring. At the connection point, the two semi-annular bodies form a first predetermined angle. The semi-annular bodies are made of flexible material, and the connecting post is made of rigid material. This invention can be conveniently implanted into the bicuspid aortic valve annuli and can be operated within the aorta, eliminating the need for dissection outside the vessel wall.

1. The name of the product of this design: the main body of the heart valve forming ring. 2. Purpose of the product of this design: The overall purpose of the product is to be used as a medical device; the partial purpose of the product is to be used as the main body of a heart valve forming ring. 3. The key design point of this design product lies in the shape of the part for which protection is sought. 4. The picture or photo that best illustrates the design points: Stereoscopic diagram 1. 5. The left view has been expressed in other views, so the left view is omitted.

A holder for an annuloplasty ring that detaches with one cut. The annuloplasty ring mounts around a periphery of the holder without the use of connecting sutures. The holder has a proximal plate defining a lip on one side of the ring, and a distal retainer that defines a second lip on the other side, the two lips retaining the ring around the holder periphery. The distal retainer is formed by two hinged wings. A truss suture maintains the holder in a trussed configuration while the annuloplasty ring is delivered and secured to the implantation site. Once the ring is secured at the annulus, the truss suture is severed with one cut, enabling the hinged wings to pivot and the holder to be pulled free of the ring.

The present disclosure describes a holder for an annuloplasty ring that is detached using a single cut. The annuloplasty ring is mounted around the periphery of the holder without the use of connecting sutures. The holder has a proximal plate that defines a lip on one side of the ring and a distal retainer that defines a second lip on the other side that retains the ring around the holder perimeter. The distal retainer is formed of two hinged wings. When the annuloplasty ring is delivered and secured to an implantation site, a truss suture maintains the holder in a trussed configuration. Once the ring is secured at the annulus, the truss suture is severed with a single cut, enabling the hinged wings to pivot and enabling the holder to be pulled away from the ring.

This invention discloses a mitral valve annuloplasty ring locking structure, comprising an annuloplasty ring body, including at least two metal strips, end metal tubes sleeved at the ends of the metal strips, and a connecting metal tube sleeved between two adjacent metal strips; the two end metal tubes are connected by a snap-fit ​​assembly so that the annuloplasty ring body is joined end to end to form a ring structure; one end of each of the two adjacent metal strips is inserted into the inner cavity of the connecting metal tube; the inner walls of the metal strips and the connecting metal tube are connected by the mitral valve annuloplasty locking structure. By providing at least two metal strips, end metal tubes sleeved at the ends of the metal strips, and a connecting metal tube sleeved between two adjacent metal strips, with the ends of the two adjacent metal strips furthest from the end metal tubes inserted into the inner cavity of the connecting metal tube, the size of the annuloplasty ring body can be adjusted by adjusting the length of the metal strips inserted into the connecting metal tube, thereby achieving the function of individually shrinking the annuloplasty ring body.

An annuloplasty ring for attachment to an annulus of a tricuspid valve comprises an elongate tube of suturable material comprising a central segment and first and second end segments. An arcuate stiffener is received in the central segment of the tube and extends the length thereof. The arcuate stiffener is circumferentially confined within the central segment to prevent circumferential movement of the stiffener relative to the tube. The first and second end segments of the tube lack a stiffener and are axially deformable.

The invention provides an adjustable artificial forming ring and a heart valve ring repairing system. The artificially formed ring includes a first set of elements, a second set of elements, a third set of elements, and an adjustment assembly. Each of the first group of elements, the second group of elements and the third group of elements comprises at least one sheet-shaped element, and every two of the first group of elements, the second group of elements and the third group of elements are partially staggered and overlapped. The adjusting assembly comprises sliding grooves formed in the first set of elements, the second set of elements and the third set of elements, a plurality of clamping grooves formed in the sliding grooves and a plurality of limiting pieces. The multiple limiting pieces are movably connected with the first set of elements and / or the second set of elements and / or the third set of elements and can move into the multiple clamping grooves along the sliding grooves, so that the manual forming ring has multiple expansion adjusting states. Therefore, the perimeter of the artificially formed ring can be freely selected within a certain range.

The invention provides an annuloplasty ring capable of inhibiting hemolysis. The annuloplasty ring includes (1) an annular core and (2) a first layer that covers the surface of the core and includes a fabric or fabric impregnated with a hydrogel, and the hydrogel is irradiated and crosslinked.

Apparatus for use with an annuloplasty ring (20), and an atrioventricular valve of a heart of a mammalian subject. A plurality of chord-manipulation arms (26) each include a flexible material and a stiffening element (70), the stiffening elements being configured to provide desired shapes to the chord-manipulation arms (26), when the chord-manipulation arms are disposed in non-radially constrained configurations. The chord-manipulation arms (26) are configured to be deployed among chords of the atrioventricular valve, and subsequently, to cause a size of the valve annulus to decrease, by the chord-manipulation arms (26) being rotated such as to twist the native atrioventricular valve and pull the native atrioventricular valve radially inwards. The stiffening elements (70) are configured to be removed from the flexible material of the chord-manipulation arms and / or de-stiffened, such as to facilitate removal of the chord-manipulation arms (26) from among the chords. Other applications are also described.

The present invention relates to an annuloplasty ring system for interventional surgery to treat tricuspid regurgitation diseases, belonging to the technical field of medical devices. It includes a clamping system for clamping the tricuspid annulus multiple times, an operating system for controlling the opening and closing of the clamping system, an annuloplasty ring system for reducing the opening of the tricuspid annulus, an adjustment system for secondarily adjusting the circumference and shape of the annuloplasty ring, a catheter delivery system, and a deflection system for adjusting the direction of the catheter; the annuloplasty ring system includes an annuloplasty ring, and a plurality of clamping systems are provided on the annuloplasty ring; the clamping system is provided with a valve annulus clip for clamping the tricuspid annulus, a locking structure, and an annuloplasty ring clip for clamping the annuloplasty ring; the locking structure includes a two-gear structure for converting the valve annulus clip to an open or closed state; the valve annulus clip can adjust its position to clamp the tricuspid annulus multiple times. The problem of tricuspid valve regurgitation is effectively solved by the present invention, and it is a relatively safe, simple, and efficient tricuspid annuloplasty ring system.

Systems and methods are provided for an annuloplasty device and delivery system for treating valvular regurgitation. The annuloplasty device (e.g., a transcatheter annuloplasty ring) may include a tube having anterior and posterior anchors that may transition from a constrained state within the tube to a deployed state in which anchors extend through windows of the tube into tissue at the native valve site. Each anchor may include valvular and atrial anchors as well as anchors having different shapes (e.g., a curved anchor and a non-curved anchor). The annuloplasty device may be delivered to the native valve site via a catheter and the annuloplasty device may be manipulated within the patient's heart using a delivery handle to selectively deploy anchors while closing the anterior-to-posterior distance of the valve to treat valvular regurgitation.

Annuloplasty rings that are size-adjustable after implant and which facilitate deployment and reduce long-term complications. The rings each have a hollow circumference with a cinching element extending therethrough whose length is controlled remotely via a deployment system handle. The ring may be anchored to the annulus and then the size adjusted while the heart beats and under visualization to minimize regurgitation. The cinching element may be a loop of metal which is clamped to size within a junction housing to which the deployment system attaches. The rings are especially beneficial for repairing the mitral annulus, and may be saddle shaped with the junction housing located on an anterior side.

An annuloplasty ring assembly with detachable handle includes an annuloplasty ring configured to be secured to an annulus of a heart valve and an annuloplasty ring. The annuloplasty ring is attached to the ring holder such that the annuloplasty ring is in conformal contact along a lower surface of a peripheral edge portion of the ring holder. The assembly includes a handle adapter extending proximally from an upper proximal face of the ring holder. The handle adapter is also attached or attachable to a distal attachment end of the handle on one side and removably attached to the annuloplasty ring holder on another side.

Systems and methods are provided for an annuloplasty device and delivery system for treating valvular regurgitation. The annuloplasty device (e.g., a transcatheter annuloplasty ring) may include a tube having anterior and posterior anchors that may transition from a constrained state within the tube to a deployed state in which anchors extend through windows of the tube into tissue at the native valve site. Each anchor may include valvular and atrial anchors as well as anchors having different shapes (e.g., a curved anchor and a non-curved anchor). The annuloplasty device may be delivered to the native valve site via a catheter and the annuloplasty device may be manipulated within the patient's heart using a delivery handle to selectively deploy anchors while closing the anterior-to-posterior distance of the valve to treat valvular regurgitation.

Disclosed herein are embodiments relating to methods for performing a minimally invasive procedure comprising delivering a linear annuloplasty ring using a delivery system. In some embodiments, the annuloplasty ring can be delivered using a transseptal or transapical approach. In some embodiments, the delivery system can position the annuloplasty ring using a flexible stabilizing mechanism and / or activate one or more anchors to extend outwardly from the annuloplasty ring.

An annuloplasty ring includes an elastic elongated core having first regions and second regions, wherein the first regions are more stretchable than the second regions and are adapted for positioning at the commissures of a target native heart valve. The first regions and the second regions may enable the annuloplasty ring to both re-establish coaptation of the leaflets of a diseased native heart valve and establish a seal around a prosthetic replacement heart to prevent paravalvular leakage after a "Valve In Ring Procedure".

A surgical annulus, a mechanical valve, and a surgical biovalve are disclosed. The three cardiac surgical valve instruments preferably adopt a high valve ring or short valve angle design. By means of the high-valve-ring surgical valve ring, left ventricular outflow tract obstruction can be avoided during a mitral valve intervention operation in the future. A mechanical valve and a surgical bioprosthetic valve move up a leaflet fixing structure and leaflets through a high annulus or short valve angle design to retain leaflets and subvalvular structures as much as possible in future mitral and tricuspid valve operations to facilitate post-operative heart function improvement.

Annuloplasty rings that are size-adjustable after implant and which facilitate deployment and reduce long-term complications. The rings each have a hollow support body with a cinching element extending therethrough whose length is controlled remotely via a deployment system handle. The ring may be anchored to the annulus and then the size adjusted while the heart beats and under visualization to minimize regurgitation. The cinching element may be a loop of braided metal cable which cooperates with a junction housing to which the deployment system attaches. The rings are especially beneficial for repairing the mitral annulus, and may be saddle shaped with the junction housing located on an anterior side. The support body may be shape set nitinol tube having cutouts for flexibility, and the cinching element may be a braided nitinol core having a braided polymer exterior. The cinching element may be a complete loop, have one end anchored in the junction housing, or have two free ends extending out of the junction housing.

The present invention discloses a valve annuloplasty ring delivery device and an annuloplasty system. The valve annuloplasty ring delivery device includes a housing member and a lead wire assembly. The housing member is axially provided with a receiving cavity for receiving a valve annuloplasty ring, and through grooves communicating with a receiving groove are axially provided on opposite sides of the housing member. The lead wire assembly includes a wire splitting member and at least one catheter with both ends communicating. The wire splitting member includes a main cavity axially penetrating therethrough and a plurality of wire splitting holes radially communicating with the main cavity. The housing member is detachably received in the main cavity, and each catheter movably penetrates through the wire splitting holes. In the valve annuloplasty ring delivery device provided by the embodiments of the present invention, the catheter penetrates through the wire splitting holes of the wire splitting member and simultaneously passes through the valve annuloplasty ring in the receiving cavity through the through groove. The suture that has been sewn into the native annulus is passed through the catheter, and after the catheter is withdrawn, a plurality of sutures on the native annulus can be coupled to the valve annuloplasty ring, with simple operation, convenience and speed. At the same time, it can ensure that the suture is arranged at a suitable position on the valve annuloplasty ring.

An annuloplasty repair segment for heart valve annulus repair and a method for forming. A multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves which allows for greater deployment flexibility for minimally-invasive surgical (MIS) implant, while still maintaining the required strength and similar tensile properties of solid-core wire. The particular shape of the annuloplasty ring is fixed using a heat setting process including heating the flexible core member to a temperature higher than 500° C. and holding it in a desired heat-set saddle shape for a period of time. The core is then rapidly cooled to impart physical properties such that the flexible core member can be straightened, during implantation, to fit through a tubular access device and regain the heat-set saddle shape after exiting the access device and, when attached to the native heart valve, the flexible core member is strong enough to remodel the native heart valve.

This invention discloses a valve annuloplasty ring, comprising a main ring and an outer layer, the outer layer covering the outer periphery of the main ring. The main ring is a closed ring formed by the cooperation of an anterior ring segment, a posterior ring segment, a left ring segment, and a right ring segment. The anterior and posterior ring segments are less flexible than the left and right ring segments, and the posterior ring segment is more flexible than the anterior ring segment. Both the left and right ring segments include multiple sequentially arranged connectors, with at least two adjacent connectors movably connected and having a gap at the connection point. This allows the connectors to extend or retract relative to an adjacent connector along the circumference of the main ring to change its circumference, and to rotate relative to an adjacent connector to deform the main ring along its circumferential and axial directions. This valve annuloplasty ring provides suitable strength to prevent annular dilation while also possessing suitable flexibility to adapt to the physiological curvature changes of the heart valve during systole-diastole-systole.

Apparatus and methods are described for use at an atrioventricular valve of a heart of a subject, the atrioventricular valve including a valve annulus, valve leaflets, chords, and papillary muscles. An annuloplasty ring is configured to be implanted on an atrial side of the atrioventricular valve. A plurality of chord-manipulation arms are configured to be deployed among the chords of the atrioventricular valve, and, subsequently, in response to being rotated, to cause a size of the valve annulus to decrease, by twisting the native atrioventricular valve and pulling the native atrioventricular valve radially inwards, by the chord-manipulation arms deflecting the chords. Subsequently, the chord-manipulation arms are configured to provide a counterforce against which the annuloplasty ring can be pushed, during implantation of the annuloplasty ring. Other applications are also described.

The present invention discloses a delivery system for a valve repair device, which includes a pushing assembly, a multi-lumen tube, a pushing tube, an outer sheath tube, a tangential mechanism, a wire pulling mechanism, a pushing mechanism and a wire pulling-out mechanism. The pushing assembly includes a first-stage handle, a second-stage handle and a third-stage handle. The third-stage handle can slide back and forth relative to the second-stage handle, and the second-stage handle can rotate relative to the first-stage handle. By sliding back and forth and rotating the second-stage handle, the distance between the valve repair device and the mitral valve can be adjusted to adjust the valve repair device when implanting the annuloplasty ring; a pushing mechanism is provided, the pushing tube is fixed at the distal end of the pusher, and then the push rod button is pushed to drive the pushing tube to move distally or proximally, so as to move the valve repair device closer to or away from the mitral valve; the pushing tube extends into the multi-lumen tube, and the outer sheath tube fixed at the distal end of the third-stage handle is arranged on the outer periphery of the multi-lumen tube, and the multi-lumen tube and the pushing tube can be pushed respectively, and the outer sheath tube is rotated to further adjust the matching degree between the annuloplasty ring and the mitral valve.

Apparatus is provided for repairing a cardiac valve, the apparatus including a catheter sized for delivery through vasculature of a subject and an elongated and flexible annuloplasty structure having an annuloplasty structure axis. The annuloplasty structure is sized and configured for delivery to a heart of the subject through the catheter substantially along a catheter axis of the catheter while the annuloplasty structure axis is substantially parallel to the catheter axis. The apparatus also includes a plurality of anchors configured for delivery to a region of cardiac tissue from a proximal end of the catheter toward a distal end of the catheter and substantially along the annuloplasty structure axis and the catheter axis while at least a portion of the annuloplasty structure is within a delivery passage of the catheter. Other embodiments are also described.

The invention provides a valve ring suture ring contraction instrument which comprises a multi-cavity tube, a mounting piece, an upper clamping arm, a lower clamping arm and a handle, the mounting piece is arranged at the far end of the multi-cavity tube, the mounting piece is provided with a first connecting part and a second connecting part, the lower clamping arm is rotationally connected to the first connecting part, the upper clamping arm is rotationally connected to the second connecting part, the upper clamping arm is provided with a probe hole, and the probe hole is communicated with the multi-cavity tube. The multi-cavity tube and the installation part are provided with communicated detection channels, detection rods capable of moving relative to the detection channels are arranged in the detection channels, the detection holes can be aligned to far-end ports of the detection channels so that the detection rods can stretch into the detection holes, and a control part capable of controlling the detection rods to move relative to the detection channels is arranged in the handle. According to the valve ring suture ring contraction instrument, the detection hole and the detection rod are arranged, so that the valve ring can be accurately clamped when ring contraction is carried out on the valve ring, and the technical problem that in the prior art, the valve ring cannot be accurately clamped when ring contraction is carried out on the valve ring is solved.

An annuloplasty ring includes an elastic elongated core having a first region and a second region, wherein the first region is more stretchable than the second region and is configured to be positioned at the commissure of a target native heart valve. The first and second regions enable the annuloplasty ring to both reconstruct the commissure of the leaflets of the diseased native heart valve and to establish a seal around the artificial heart to prevent paravalvular leakage after "annular valve in-circuit surgery".