77 results about "Pulsatile flow" patented technology

An embodiment includes a system comprising: an artery, a vein, and a nerve; a first length of tubing adjacent at least one of the vein, artery, and nerve; a second length of tubing to couple to the first length of tubing; and a pump comprising a number of actuators; wherein when the system when operating is configured such that (b)(i) the second length of tubing couples to at least one of the number of actuators, (b)(ii) ends of the first and second lengths of tubing are closed, (b)(iii) a second end of the first length of tubing is operatively coupled to a second end of the second length of tubing, (b)(v) the pump pulsates fluid within the first length of tubing in response to the number of actuators intermittently contacting the second length of tubing.

The invention discloses an artificial heart valve near-physiological pulsation fluid external evaluation device and method, and relates to the technical field of heart valve testing.The artificial heart valve near-physiological pulsation fluid external evaluation device comprises a supporting frame, a driving unit, a tested valve installation unit and an artery and peripheral loop unit, the driving unit provides power for liquid flowing, and the tested valve installation unit is used for fixing an artificial heart valve; and a liquid volume assembly and a resistance assembly of the artery and peripheral loop unit can simulate the compliance and resistance of aorta blood vessels and peripheral artery blood vessels, so that the pressure waveform simulation of the systemic circulation loop is more accurate. On the basis of the air cavity, the elastic corrugated pipes with different frequency responses are arranged, the compliance and rebound resilience of the aorta are simulated, a device for rapidly replacing the tested valve is designed, and the mechanical property of the simulated human body aorta is adjusted by adjusting the parameters such as the output frequency and the vibration amplitude of the driving unit; real pressure and flow waveforms under different physiological / pathological conditions are simulated, and a more accurate and convenient detection environment is realized.

The invention provides an artificial heart valve thrombus risk assessment method and device. The thrombus risk assessment method for the artificial heart valve comprises the following steps: acquiring a physiological scene after the artificial heart is implanted into the artificial valve through a resistance characteristic parameter and an elastic expansion characteristic parameter; starting a pulsating pump to output a pulsating flow medium to the artificial heart in a physiological scene; capturing the motion trail of the fluorescent particles through a high-speed camera and obtaining the original data of the blood flow velocity at the downstream of the artificial valve; acquiring a fluid mechanics simulation parameter group according to the blood flow velocity original data; and inputting a pre-trained valvular thrombus random forest classifier according to the fluid mechanics simulation parameter group, and outputting a thrombus risk probability graph in the physiological scene. According to the method, the fluid mechanics simulation parameter group is calculated based on the instantaneous velocity vector field captured by the PIV and the space-time distribution information, the two-dimensional / three-dimensional thrombus risk probability graph is generated through the random forest classifier, the high-risk point coordinates are marked, and the thrombus probability and the thrombus position are accurately predicted.

A continuous flow reaction device (100) for an electrochemical process comprising: a reaction space (110), a pumping system (200) configured to generate a pulsatile flow, a plurality of discrete protrusions (120,a: 120,b) each configured such that a flow path (150a-150c) of the fluid contacting an inlet end (14) side of the discrete protrusion is split at least into two daughter flow paths (150b1; 150b2) on the outlet end (16) side of the discrete protrusion (120,a: 120,b); and the discrete protrusions (120,a: 120,b) being arranged so that at least one of the daughter flow paths (150b1) generated by one of the plurality of discrete protrusions (120) combines (152a) with at least one of the daughter flow paths (150a2) generated by another of the plurality of discrete protrusions (120) on the outlet end (16) side of both discrete protrusions (120) and wherein each (and every) discrete protrusion (120) is an electrode in the electrochemical process.

The invention relates to the technical field of medical instrument volume detection, and discloses a medical instrument internal volume detection system. A continuous wave and a pulse modulation signal are simultaneously transmitted through an annular phased array microwave antenna array, three-dimensional dielectric constant distribution is reconstructed by adopting a compressed sensing algorithm, and Doppler time-frequency domain characteristics are extracted through short-time Fourier transform; and inputting the phase gradient field and Doppler velocity field features into a convolutional neural network to generate a four-dimensional space-time volume evolution model, separating a macroscopic volume trend and a microcosmic pulsation component by adopting an adaptive Kalman filtering algorithm, and predicting an abnormal hemodynamic event through a long-short-term memory network. The technical problem of real-time precise detection of the multi-dimensional volume parameters of the blood circulation medical instrument under the complex pulsating flow condition is solved, and accurate evaluation of the instantaneous volume value, the pulsation amount and the pulsating frequency spectrum and early warning of abnormal events are achieved.

An implantable LVAD is provided that includes a pump shaped so as to define a pump chamber. The pump includes a tubular linear motor, which includes a magnetic piston, which includes a reciprocating one-way valve configured to allow downstream blood flow and inhibit upstream blood flow; and a stator, which is configured to magnetically drive the magnetic piston with reciprocating motion, so as to pump blood downstream during downstream motion of the magnetic piston while the reciprocating one-way valve is closed. The pump further includes a spring, which is arranged to store energy during upstream motion of the magnetic piston and release the stored energy during the downstream motion of the magnetic piston. Control circuitry is configured to activate the tubular linear motor to provide pulsatile flow synchronized with cardiac cycles. Other configurations are also described.

An implantable LVAD system includes an implantable LVAD including an outflow cannula, which is couplable in fluid communication with a circulatory system of the patient at a first site; and an inflow cannula, which is couplable in fluid communication with the circulatory system at a second site upstream of the first site. The LVAD further includes a continuous-flow pump includes a first inlet in fluid communication with the inflow cannula, and a first outlet. The LVAD still further includes a pulsatile-flow pump includes a second inlet in fluid communication with the first outlet of the continuous-flow pump, and a second outlet in fluid communication with the outflow cannula. Control circuitry is configured to activate the continuous-flow pump to provide flow without synchronization with cardiac cycles of a heart of the patient, and activate the pulsatile-flow pump to provide pulsatile flow synchronized with the cardiac cycles. Other embodiments are also described.

The invention relates to the technical field of gas metering, and discloses an ultrasonic gas meter time sampling method aiming at pulsating flow influence, comprising the following steps: S1, setting a basic acquisition period and random sampling related parameters; s2, sampling time is dynamically generated through a random algorithm, and interference matching of a fixed period is avoided; s3, collecting instantaneous flow at the generated random sampling time point; s4, abnormal value detection and elimination are carried out on the collected instantaneous flow data; s5, correcting the flow data after the abnormity is eliminated, and calculating the corrected instantaneous flow; and S6, outputting the corrected instantaneous flow, and adjusting random sampling parameters and exception handling rules based on historical data feedback. According to the method, through a dynamic adjustment method in combination with the flow fluctuation amplitude, the sampling time distribution is more flexible and uniform, different flow modes are adapted, the influence of periodic interference on the sampling data can be remarkably reduced, and the accuracy and the stability of instantaneous flow sampling are improved.

A pump system is provided comprising a diaphragm fluid pump which can be fluidically connected to a heart and / or at least one blood vessel by means of an inlet cannula and an outlet cannula and is adapted for generating a pulsatile fluid flow for supporting a cardiac activity of the heart, a working pressure source connected to the diaphragm fluid pump by means of a pressure line and adapted for providing a working pressure for driving the diaphragm fluid pump, a control unit adapted for controlling the working pressure, a first flow sensor adapted for detecting a first cannula flow signal corresponding to an inlet flow in the inlet cannula or an outlet flow in the outlet cannula, a working pressure sensor adapted for detecting a working pressure signal corresponding to the working pressure in the pressure line.

The utility model discloses a fuel gas rectifier and a flow meter. The fuel gas rectifier comprises a hollow cylindrical part, the mounting ring is arranged on the outer end face of the cylindrical part; a plurality of shunting channels which extend in the length direction of the cylindrical part and are not communicated with one another are uniformly distributed in the cylindrical part; according to the flow meter, after the gas medium entering the flow meter is rectified by the rectifier, pulsating flow energy existing in fluid is completely dispersed, the fluid is transited to a laminar flow state from a turbulent flow state, the influence of pulsating flow is eliminated, and the flow meter has the advantages of being simple in structure, convenient to use and high in efficiency. Therefore, the fluid detection effect of the ultrasonic flowmeter is effectively improved.

Methods and systems for delivery of pulsated air to a user using a device including a flow generator to generate a continuous air flow, a first actuator comprising a pulsated flow delivery mechanism configured to generate a pulsated air flow from the continuous air flow based on a pre-determined duty cycle to vary a frequency of the pulsated air flow, a user interface configured to generate and deliver vortices of pulsated air to the user at the frequency of the pulsated air flow, and a set of tubing to couple the flow generator, the first actuator, and the user interface.

This invention relates to a ball-operated plugging device for downhole pulsating hydraulic fracturing, comprising a main body assembly. A conical valve seat is disposed in the middle of the main body assembly, and an umbrella-shaped valve is slidably connected within the conical valve seat. The umbrella-shaped valve includes a valve head boss and a valve stem. A self-excited oscillation chamber is also provided at the bottom of the conical valve seat. A spring support seat is disposed below the self-excited oscillation chamber, with a central circular hole at the geometric center of the spring support seat. A spring is placed on the spring support seat, and the top of the spring contacts the valve head boss of the umbrella-shaped valve. A through-hole flow channel is provided in the middle of the umbrella-shaped valve, with its upper and lower ends communicating with cavity A and cavity B, respectively. The valve stem of the umbrella-shaped valve passes through the spring, and its bottom is inserted into the central circular hole of the spring support seat. A spherical groove is provided at the top of the umbrella-shaped valve for placing a soluble plugging ball. This invention can adjust the pressure variation of the pulsating fluid at the bottom of the well during construction.

The present application provides a kind of vascular anastomat performance testing device and method, for evaluating the performance of vascular anastomosis in tensile property and leakage property.The device includes a simulated blood flow part, a loading test part and an anastomosis experiment part.The simulated blood flow part includes a centrifugal pump, a solenoid valve, a temperature transmitter, a pressure transmitter, a flowmeter, a throttle valve, a heater and a liquid tank, for simulating the physical characteristics of actual blood pulsatile flow, the loading test part is used to evaluate the characteristics of the anastomosis performance of the anastomosis under load.The anastomosis experiment part can be used for vascular anastomosis experiment and leakage property evaluation in this part, to detect the leakage of anastomat in simulated blood flow circuit.The present application can comprehensively evaluate the performance of vascular anastomat, and provide reliable test data for clinical application.

The present application discloses a blood pump speed pulsation control method, system, and related products. The method: based on the electrical signal change information of the blood pump motor within a historical period, detects the start time of the N0 diastole and the start time of the N0 systole of the current patient's heart beat within the historical period; based on these start times, determines the start time of the N1 diastole and the start time of the N1 systole of the heart after the historical period. The method uses the patient's individual historical electrical signal change information as a basis to determine the future start time of the diastole and the start time of the systole of the current patient's heart, ensuring that the speed adjustment time of the blood pump motor is personalized to conform to the physiological contraction law of the individual heart, and realizing the specific output of the blood pump such as the blood pumping time and the blood pumping volume per time to flexibly follow the blood flow pulsation output of the heart beat, that is, to assist the blood pump in generating a pulsating flow synchronized with the natural heart beat, thereby effectively and reliably maintaining the patient's life safety.

The invention relates to a valve pulsating flow test system which comprises a circulation test loop, a heart simulation system and a pulsating pump, the circulation test loop comprises a first simulation system, a test channel, a second simulation system and a water return channel which are connected in sequence, and gate valves are arranged at the two ends of the test channel; the test channel can be detachably installed between the first simulation system and the second simulation system in a forward or reverse mode, the test channel comprises a flowmeter assembly detachably installed at the water inlet end of the test channel, and the first simulation system comprises a first simulation cavity. The one-way valve can be detachably mounted on the first simulation cavity in a forward or reverse manner; the heart simulation system is connected with the first simulation system; the pulsating pump is connected with the heart simulation system. According to the invention, rapid switching of the installation directions of the one-way valve and the flowmeter can be realized, the test requirements of different types of test samples can be met, and the test efficiency is further improved.

An apparatus for generating a controlled pressure pulsatile flow includes: a fluid flow path extending from a reservoir to an application; a primary pump disposed in the fluid flow path downstream of the reservoir; a reference pump; a variable speed electric motor coupled to the reference pump; a bleed orifice connected in fluid communication with the reference pump; a pressure relay device configured to communicate a reference pressure from the reference pump to the fluid flow path; and an electronic controller configured to selectively supply electric power to the electric motor so as to generate a pulsatile fluid flow in the fluid flow path.

A dampening device includes a housing including an inlet and an outlet, and a section of compliant tubing extending through the housing between the inlet and the outlet. A first portion of the housing is movable relative to a second portion of the housing to vary fluid flow characteristics within the section of compliant tubing. A dampening device includes a housing defining an interior volume, wherein the housing includes an inlet and an outlet, and an actuation mechanism configured to change the interior volume thereby changing fluid flow characteristics through the housing. A method of smoothing a pulsatile fluid flow includes coupling the dampening device to an inflow line, activating the fluid pump, wherein the section of compliant tubing expands within the housing to smooth out the pulsatile fluid flow, and selectively moving a first portion of the housing relative to a second portion to vary fluid flow characteristics.

The present application discloses a blood pump flow adaptive control method, system and related products. The embodiments of the present application use the patient's individual historical electrical signal change information as a basis to determine the start time of the diastole and the start time of the systole of the current patient's heart in the future, which can ensure that the speed adjustment time of the blood pump motor is personalized and conforms to the physiological contraction law of the individual heart; wherein, the start time of the current beating period is determined according to the duration of one single historical beating period, and the start time of the next beating period is detected within the latest corresponding duration of the current beating period, which can achieve the specific outputs of the blood pump such as the blood pumping time and the blood pumping volume each time to flexibly follow the blood flow pulsation output of the heart beat in real time, that is, to assist the blood pump in generating a pulsating flow synchronized with the natural heart beat, thereby effectively and reliably maintaining the patient's life safety.

A vascular simulator based on pulsatile flow control and a method for controlling same are disclosed. The control method according to the present disclosure may comprise the steps of: acquiring pressure sensing information of an artificial blood vessel outlet region due to the flow of artificial blood through a pressure sensor corresponding to the artificial blood vessel outlet region; identifying an outlet pressure corresponding to the artificial blood vessel outlet region on the basis of the pressure sensing information; if the outlet pressure is identified, identifying whether the outlet pressure matches a preset condition; and if the outlet pressure does not match the preset condition, controlling a valve corresponding to the outlet such that the outlet pressure matches the preset condition.

A pump valving assembly for a pulsatile fluid pump includes a pumping chamber, an inlet port, and an outlet port. The pump valving assembly further includes an inlet spherical check valve assembly, first and second tapered tubes disposed between the inlet port and the pumping chamber, an outlet spherical check valve assembly, and third and fourth tapered tubes disposed between the pumping chamber and the outlet port. The first tapered tube expands in cross-sectional area from the inlet port to the inlet spherical check valve assembly, and the second tapered tube contracts in cross-sectional area from the inlet spherical check valve assembly to the chamber. The third tapered tube expands in cross-sectional area from the chamber to the outlet spherical check valve assembly, and the fourth tapered tube contracts in cross-sectional area from the outlet spherical check valve assembly to the outlet port.

A system for simulating cardiovascular fluid flow having a target fluid flow profile, which has target pulsatile flow and target systemic resistance components, in a test member is disclosed. The system includes a reservoir, a pump, input and output channels, a first valve in the input channel, a second valve in the output channel, and a processor. The input and output channels are connectable to the test member so as to form a fluid circuit with the test member. The processor is configured to execute a method for controlling the first valve to generate the target pulsatile flow component in the input channel, and controlling the second valve to generate the target systemic pressure component. Other systems are also disclosed. Methods for simulating target fluid flow profiles in a test member are also disclosed.

A pump includes: a first pump body defining a first flow path; a first inlet check valve at an upstream end of the first flow path; a first outlet check valve at a downstream end of the first flow path; a first compressible container in flow communication with the flow path between the upstream and downstream ends; a first electromagnetic linear motor connected to the first compressible container such that extension of the first linear motor causes compression of the first compressible container; and an electronic controller configured supply a varying voltage or current to the first linear motor so as to provide a pulsatile flow at a controlled pressure and controlled pulse rate, where the pressure is independent of downstream flow resistance.

The utility model relates to the technical field of water pump pulsation monitoring, in particular to a water pump pulsation monitoring unit which comprises a water pump body composed of a pump body motor and a volute, a vibration sensor is fixedly installed on the inner side of a hollow ring, and a first pressure sensor is fixedly installed on the top of a water inlet pipe. A flow sensor is fixedly installed at the bottom of the water inlet pipe, a second pressure sensor is fixedly installed outside the water drainage pipe, and an electromagnetic flowmeter is fixedly installed at the top of the water drainage pipe. According to the water pump pulsation monitoring unit, vibration data of the transmission shaft are detected through the eddy current sensing probe of the vibration sensor, data support is provided for pressure pulsation data analysis, and water pressure and flow velocity data of the water inlet pipe are detected through the first pressure sensor and the flow sensor; and then the second pressure sensor is used for detecting water pressure data at the drainage pipe, pulsating flow data are rapidly detected through the electromagnetic flowmeter, and the data accuracy is improved through comparative analysis.

This invention provides a pulsating flow generator that can efficiently pulsate the pressure of a liquid, has a simple configuration, and is highly durable. [Solution] The problem of the present invention is solved in a pulsating flow generator 1 provided in a flow path between a liquid supply means and a nozzle that sprays liquid, which causes the flow rate of the liquid sprayed from the nozzle to change in accordance with the pressure pulsation by causing the pressure of the liquid flowing through the flow path to pulsate. The pulsating flow generator 1 comprises a main body 2 having a main flow path through which liquid flows from the liquid supply means toward the nozzle, and a pulsation generating unit 4 having a volume fluctuation unit that alternately absorbs and releases the liquid flowing through the main flow path via a branch path to which the flow path branches off, thereby increasing and decreasing the internal volume. The pulsation generating unit 4 solves the problem by alternately repeating a filling step of absorbing liquid from the main flow path and a release step of releasing the absorbed liquid into the main flow path when liquid is supplied at the input liquid pressure, thereby superimposing the fluctuating volume fluctuation pressure on the input liquid pressure of the liquid and causing the liquid pressure to pulsate.

The present disclosure provides a fluidic device including a first inlet, an outlet, and a channel positioned between the first inlet and the outlet. The channel is in fluid communication with the first inlet and the outlet. The fluidic device further includes a second inlet positioned between the first inlet and the outlet. The second inlet is in fluid communication with the channel. The fluidic device further includes a pump in fluid communication with the second inlet. The pump is configured to provide a first volume of pulsatile flow to the channel. The first volume of pulsatile flow is greater than about 50 μL per pulse.

The invention discloses a pulsating flow blood injury assessment system and method for a double-loop nested low-pre-charge medical instrument, and belongs to the technical field of medical instruments. The system comprises a physiological pulsating pressure simulation loop and an instrument test blood carrying loop. The physiological pulsating pressure simulation loop is composed of a mechanical human body circulation simulation system and comprises a left ventricle, an aorta compliance cavity, a pipeline, a sensor and a power system. The instrument test blood carrying loop comprises a flexible blood bag, a blood carrying pipeline and a to-be-tested medical instrument. The two loops are nested and coupled through the flexible blood bag, and the flexible blood bag is immersed in water-glycerol liquid of the physiological pulsating pressure simulation loop to realize non-contact pressure transmission. The total blood pre-filling amount of the system is smaller than 500 mL, an SEBS blood bag and a heparinization coating are adopted, a non-contact sensor and an actuator are combined, and extra blood damage is remarkably reduced. According to the invention, low-pre-charge and high-biocompatibility pulsating flow blood injury accurate evaluation is realized, and the method is suitable for blood compatibility test of medical instruments such as a ventricular assist device and the like.

An actuator actuated diverter valve for maintaining multi-lumen patency may include a valve manifold, a valve spool, and a rotary actuator. The valve manifold may include an input port, a first output port, and a second output port. The valve spool may extend within the valve manifold. The valve spool may define a first valve passageway and a second valve passageway, and the valve spool may be rotatable relative to the valve manifold between a first position in which the input port and the first output port are in fluid communication via the first valve passageway and a second position in which the input port and the second output port are in fluid communication via the second valve passageway. The rotary actuator may be configured to rotate the valve spool relative to the valve manifold between the first position and the second position.

The invention discloses a left heart circulation pulsating flow test system and test method. The test system comprises a controller, a rack and a circulation loop, the circulation loop is arranged on the rack, a vein system in the circulation loop is connected with an inlet of a left atrial cavity, an outlet of the left atrial cavity is connected with a left ventricular model, and the left ventricular model is arranged in the left ventricular cavity; an outlet of the left ventricle model is connected with the aorta model which simulates a real human physiological structure; an outlet of the aorta model is connected with the artery compliance cavity, and an outlet of the artery compliance cavity is connected with the vein system. A servo electric cylinder is adopted in the power executing mechanism, a piston is pushed through the servo electric cylinder, piston displacement, system flow and pressure of all cavities are monitored, and the real left ventricle movement rule of the human body physiology is simulated. The device is stable in operation, reliable in performance and high in precision.

A fluid management system may include a fluid pump capable of generating a pulsatile flow of fluid, a fluid pathway for transporting the pulsatile flow of fluid from a fluid source through the fluid pump to a medical device, a dampening element in fluid communication with the fluid pathway and operably independent of the fluid pump, the dampening element comprising one or more barrels, each barrel including a movable seal member disposed within the barrel and a biasing member disposed within the barrel and engaged with the movable seal member, the dampening element being responsive to pressure fluctuations of the pulsatile fluid flow to actively dampen the pressure fluctuations, and a fluid flow sensor disposed along the fluid pathway between the dampening element and the medical device to measure a flow rate of the smoothened pulsatile fluid flow in both flow directions.

This invention provides a systemic-pulmonary dual-circulation simulation system for testing the hemodynamic performance of an artificial heart. It includes a cardiovascular silicone model, a ventricular pulsation device, a controller, a data acquisition device, a fluid reservoir, and an artificial heart. The cardiovascular silicone model, ventricular pulsation device, and fluid reservoir are connected in series to form a blood circulation loop. The cardiovascular silicone model includes systemic and pulmonary circulation loops; the ventricular pulsation device has an internal electric cylinder that drives a piston to reciprocate via a push rod, causing fluid flow in the blood circulation loop; the controller controls the movement of the ventricular pulsation device to simulate blood flow with physiological pulsatile flow characteristics; the data acquisition device collects pressure and flow rate data at different locations on the cardiovascular silicone model. This invention can not only completely simulate the blood flow patterns of the human cardiovascular system but also be used to test the impact of artificial heart implantation on the hemodynamic performance of the human cardiovascular system under different physiological conditions, contributing to the development and research of artificial hearts.