663results about How to "Raise count" patented technology

Compositions, methods and kits are disclosed for high-sensitivity single molecule digital counting by the stochastic labeling of a collection of identical molecules by attachment of a diverse set of labels. Each copy of a molecule randomly chooses from a non-depleting reservoir of diverse labels. Detection may be by a variety of methods including hybridization based or sequencing. Molecules that would otherwise be identical in information content can be labeled to create a separately detectable product that is unique or approximately unique in a collection. This stochastic transformation relaxes the problem of counting molecules from one of locating and identifying identical molecules to a series of binary digital questions detecting whether preprogrammed labels are present. The methods may be used, for example, to estimate the number of separate molecules of a given type or types within a sample.

An apparatus and method for simultaneously displaying both record names and the associated files responsive to a user's search over a database. A user conducts a routine search query over a database or group of databases of records containing, for example, text documents, or alphabetical concordances thereof. The search engine returns a list of records responsive to the user's query. In contrast to the standard list of record identifiers, the apparatus displays both the identifiers and selected portions of those records or other useful information, as defined by the user, facilitating quick review. The user is able to sort the list of these responsive records in a variety of ways, either before the search, or within the list of results, to expedite review. The apparatus identifies records that have been reviewed previously by marking them as “viewed” links. Finally, when reviewing any responsive record in full, the complete list of records is displayed in a side panel, in a way that still allows resorting by the user. This side panel display may be re-sorted “on the fly.” It also allows the user to see the identifiers of records anywhere in the list, and to easily jump, such as with a single mouse click, to any record in the list.

Pharmaceutical compositions comprising a nucleic acid, a gene delivery polymer, and at least one adjunctive chemotherapeutic drug for the treatment of mammalian cancer or hyperproliferative disorders and methods of using thereof for the treatment of mammalian cancer or hyperproliferative disorders by intratumoral, intraperitoneal or systemic injection.