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99results about How to "Release stability" patented technology

Genetically engineered exosome as well as slow release method and application thereof

The invention discloses a gene engineering exosome and a slow release method and application thereof, the gene engineering exosome is derived from human adipose-derived stem cells, si-tgfbr2 is loaded in the gene engineering exosome, the si-tgfbr2 is specific siRNA aiming at a Tgfbr2 gene, and the gene engineering exosome can regulate and control proliferation of VSMCs, inhibit transformation of the VSMCs from a contraction phenotype to a synthetic phenotype when the VSMCs are stimulated, and inhibit the growth of the VSMCs. According to the present invention, the gene engineering exosome can be used to maintain the normal structure and the function of the blood vessel, and the sustained release effect of the content in the gene engineering exosome can be achieved by wrapping the gene engineering exosome in the PHA biodegradable material, such that the local treatment concentration can be easily stabilized, the drug administration frequency can be easily reduced, the lasting time of the treatment effect can be easily prolonged, and the treatment gene can be effectively delivered to the target cell; the treatment effect is improved; when being used for modifying a small-caliber artificial blood vessel, the small-caliber artificial blood vessel can be improved in biocompatibility and functionality, and can be prevented from being implanted into the blood vessel for remodeling unbenign hyperplasia stenosis; the invention not only provides a new thought and method for the treatment of vascular diseases, but also has important clinical application value and popularization prospect.
Owner:FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE

Pharmaceutical composition, rod core, implant and preparation method and application thereof

The invention provides a pharmaceutical composition, a rod core, an implant and a preparation method and application thereof. The pharmaceutical composition comprises the following components in parts by weight: 1-1000 parts of active pharmaceutical ingredients; 100 parts of R-vinyl silicone rubber; hydrogen-containing silicone oil; 0.000002 to 1 part of a catalyst; r in the R-vinyl silicone rubber is substituted or unsubstituted C1-C5 straight-chain alkane or branched alkane, and substituted or unsubstituted C6-C20 aromatic hydrocarbon; the content of vinyl in the R-vinyl silicone rubber is 0.10 to 0.50 mol%; the content of Si-H groups in the hydrogen-containing silicone oil is 0.15 to 1.6 mol percent; the molar ratio of Si-H group in the hydrogen-containing silicone oil to vinyl in the R-vinyl silicone rubber is (0.5-20): 1. The implant provided by the invention can reduce drug loss and sudden release phenomenon, the drug release is more stable, and the production speed is greatly increased.
Owner:SHENYANG PHARMA UNIV +1

Nimodipine nasal-brain delivery preparation as well as preparation method and application thereof

The present invention provides a high brain targeting, safe and noninvasive nasal-brain delivery preparation, which is characterized in that the nasal-brain delivery preparation comprises nimodipine, a good solvent, a diluent and an absorption enhancer, the good solvent is diethylene glycol monoethyl ether, and the absorption enhancer is phospholipid. The nasal-brain delivery preparation is prepared from a good solvent, a diluent, an absorption enhancer and the like according to a specific proportion. Nimodipine serving as an active ingredient is enriched in cerebrospinal fluid and brain tissues through a specific upper nasal meatus administration technology, so that the treatment effect of nimodipine is achieved; and meanwhile, the blood entering proportion is reduced, so that the cardiovascular toxicity and hepatotoxicity are reduced. In addition, the preparation formula has no irritation to local parts of the nasal cavity, and the compliance of a patient is improved.
Owner:NASOFIDE (SHANGHAI) PHARM TECH CO LTD

Solid / gas two-phase explosive wave driven aircraft ground test device and method

The invention relates to an explosion impact test technology, in particular to a solid / gas two-phase explosive wave driven aircraft ground test device and method, and the solid / gas two-phase explosive wave driven aircraft ground test device comprises an anti-static floor, a gas distribution system, a test system, a solid explosive fixed initiation device and a tunnel system, the tunnel system comprises a fixed support, a tunnel, a gas circulator, a first gas exchange pipeline and a second gas exchange pipeline, the gas distribution system comprises a high-pressure gas tank, a high-pressure methane gas cylinder and an air exchanger, and the test system comprises an electronic exploder, a pressure sensor and a flame sensor. Modulation of different overpressures and different durations can be carried out by controlling the solid charge amount, the gas concentration, the solid explosive charge amount, the solid explosive type and the like, the overpressure peak value and the duration of explosion shock waves are adjustable and controllable, and the requirement that external loads of an aircraft continuously change in different flight environments is met.
Owner:INST OF ENG PROTECTION NAT DEFENSE ENG RES INST ACAD OF MILITARY SCI CHINESE PEOPLES LIBERATION ARMY

Solid hydrogen storage alcohol hydrogen gasoline, diesel oil and natural gas multi-fuel internal combustion engine

The invention provides a solid hydrogen storage alcohol hydrogen gasoline, diesel oil and natural gas multi-fuel internal combustion engine, and relates to the technical field of internal combustion engine fuels, the solid hydrogen storage alcohol hydrogen gasoline, diesel oil and natural gas multi-fuel internal combustion engine comprises a multi-fuel internal combustion engine body; the gas storage tank is communicated with a gas inlet pipe of the multi-fuel internal combustion engine body, and a flow regulating valve is mounted on the gas inlet pipe; the hydrogen supply assembly and the natural gas supply assembly are respectively connected with the gas storage tank; a methanol reforming furnace jacket is arranged on the periphery of the methanol reforming furnace, and the methanol reforming furnace is connected with a methanol and gasoline and diesel oil supply assembly; a solid hydrogen storage tank jacket is arranged on the periphery of the solid hydrogen storage tank, the solid hydrogen storage tank is connected with a hydrogen injection pipe and a hydrogen discharge pipe, and the hydrogen discharge pipe is communicated with the gas storage tank. According to the invention, the supply of one or more fuels can be flexibly provided for the internal combustion engine, and the conversion rate of the fuels in the conversion process is relatively high.
Owner:NINGBO YONGCHENG NEW ENERGY TECHNOLOGY CO LTD

Agomelatine pharmaceutical composition as well as preparation method and application thereof

ActiveCN119632941ADissolution rate is stableNo burst phenomenonOrganic active ingredientsNervous disorderCelluloseSucrose
The invention relates to the technical field of medicines, in particular to an agomelatine pharmaceutical composition as well as a preparation method and application thereof. The agomelatine pharmaceutical composition comprises inner-layer particles, a coating layer and outer-layer auxiliary materials, the inner-layer particles are prepared from the following raw materials: agomelatine, hydroxypropyl methylcellulose, mannitol and colloidal silicon dioxide; the coating layer is obtained by coating a chitosan-sodium carboxymethyl starch suspension on the surfaces of the inner-layer particles; the outer-layer auxiliary material is prepared from the following raw materials: glyceryl behenate, cane sugar, povidone, sodium carboxymethyl starch and magnesium stearate. The agomelatine pharmaceutical composition provided by the invention is stable in dissolution, extremely low in impurity content, controllable in quality and excellent in stability, and can be used for treating depression and related diseases thereof.
Owner:宝利化(南京)制药有限公司

Intravascular stent

PendingCN119564388AImprove stabilityimprove long-term performanceStentsMedical devicesDrug release rateRestenosis
The invention relates to the technical field of medical instruments, in particular to an intravascular stent. According to the specific technical scheme, the intravascular stent comprises a stent skeleton, after the stent skeleton is subjected to surface treatment, at least one layer of film covering section is arranged outside the stent skeleton, and medicine release sections are arranged at the two ends of the stent skeleton. The problems that in the drug release process of an existing stent, the drug release rate is uneven, biocompatibility is poor, and thrombus and restenosis are caused by a metal stent are solved.
Owner:THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

Titanium product surface long-acting stable antibacterial coating and preparation method thereof

PendingCN119553334AGuaranteed antimicrobial propertiesrelease stabilitySurface reaction electrolytic coatingMetal particleTitanium
The invention discloses a long-acting stable antibacterial coating on the surface of a titanium product and a preparation method. The preparation method specifically comprises the following steps: pre-treating the titanium product; then, the titanium product is subjected to anodic oxidation twice, ultrasonic cleaning and drying, and a titanium dioxide nanotube pre-implanted with the copper element is prepared; and performing hydrothermal reaction on the titanium dioxide nanotube pre-implanted with the copper element for four times, cleaning and drying to obtain the long-acting stable antibacterial coating on the surface of the titanium product. According to the method, the gradient copper element nanotube is prepared through anodic oxidation of the pre-implanted copper element and four hydrothermal reactions, the coating of a gradient structure in which the content of the copper element is gradually increased from the interior of the nanotube to the exterior is obtained, and the copper element can be stably released while the antibacterial performance of the titanium product is guaranteed; the problems that an existing antibacterial metal doped titanium alloy is short in antibacterial effect lasting time, unstable in metal particle release and poor in antibacterial property are solved, and the titanium alloy serves as a long-acting and stable antibacterial coating on the surface of a titanium product and has good application prospects.
Owner:XIAN UNIV OF TECH

Antibacterial gel composite material as well as preparation method and application thereof

The invention discloses an antibacterial gel composite material as well as a preparation method and application thereof. The antibacterial gel composite material comprises photo-crosslinking hydrogel, and the photo-crosslinking hydrogel is coated with a drug-loaded mesoporous material; the drug-loaded mesoporous material comprises polydopamine, mesoporous biological ceramic and a growth factor which are arranged in sequence; the surface of the mesoporous biological ceramic is coated with polydopamine; growth factors are encapsulated in the mesoporous biological ceramic; the mesoporous biological ceramic is doped with metal ions with an antibacterial effect. According to the antibacterial gel composite material provided by the invention, in the composite material, mesoporous biological ceramic is coated with polydopamine, so that ionic products and doped antibacterial ions in drugs and biological ceramic can be slowly released, the burst release is relatively small, and stable release is realized; in addition, by regulating and controlling the doping amount of the antibacterial ions in the porous biological ceramic and the mass of the medicine loaded in the doped mesoporous biological ceramic, the release curve of the medicine and the ions can be effectively regulated and controlled.
Owner:GUANGDONG PROV MEDICAL INSTR INST

Blinarin targeted slow-release nano drug-loading system as well as preparation method and application thereof

The invention belongs to the technical field of medicines, and particularly relates to a linarin targeted slow-release nano drug-loading system as well as a preparation method and application thereof. A polylactic acid-polyglycolic acid copolymer is used as a matrix, polyvinyl alcohol is used as a cross-linking agent, and coated drug-loaded microspheres are formed through cross-linking and grafting of the matrix and the cross-linking agent; and then chitosan is used as a protective agent, chitosan and the coated drug-loaded microspheres are crosslinked and grafted to form double-coated composite drug-loaded microspheres, the chitosan in the composite drug-loaded microspheres is used as a shell, the coated drug-loaded microspheres are used as a core, and the linarin targeted slow-release nano drug-loaded system is obtained. Through the double-target design, the targeting property to cornea and lacrimal gland is enhanced, the treatment efficiency of the medicine is improved, stable release and continuous release of linarin are realized, and the problem of unstable release of the medicine is solved; in addition, the targeted slow-release nano drug-loading system is combined with the anti-inflammatory activity and the mitochondrial protection function of linarin, so that the side effects on eyes are reduced, and the safety is improved.
Owner:HUNAN UNIV OF CHINESE MEDICINE

Diaphorina citri slow-release attractant and preparation method thereof

The invention discloses a diaphorina citri slow-release attractant and a preparation method thereof, the diaphorina citri slow-release attractant is composed of ethyl butyrate, myrcene, p-cymene, a paraffin carrier and cellulose acetate tows, and the ethyl butyrate, the myrcene, the p-cymene and the paraffin carrier are mixed and filled in the cellulose acetate tows. The diaphorina citri slow-release attractant provided by the invention has efficient attraction activity on diaphorina citri adults, the preparation method of the slow-release attractant is simple, low in cost, high in operability and suitable for industrial production, the oxidation and decomposition speed of active ingredients in ethyl butyrate, myrcene and cymene can be reduced by dissolving paraffin, and the effect of inducing diaphorina citri adults is achieved. The active ingredients are stably and continuously released for at least 20 weeks, and the composition is suitable for directly trapping and killing or monitoring diaphorina citri in the field.
Owner:ZHONGKAI UNIV OF AGRI & ENG +1

Mini wedge splitting test device and method for testing fracture parameters of quasi-brittle materials

This invention discloses a micro-wedge splitting test device and a method for testing fracture parameters of quasi-brittle materials. The device includes a micro-sample, a groove on the upper part of the micro-sample, and a force-transmitting component. The force-transmitting component comprises a wedge, a roller, and a force-transmitting block connected in sequence. Compared with existing standard wedge splitting test devices, the ratio of the fracture cross-section to the volume of the micro-sample increases by more than 1.8 times, and the ratio of the shoulder width to half-width of the micro-sample decreases by less than 10%. By controlling the ratio of fracture cross-section to sample volume and the ratio of sample shoulder width to sample half-width, the device can reduce the size of the wedge splitting test device while ensuring that the crack forms and propagates stably at the center. Furthermore, by limiting the load rate to approximately 0.1 mm / min, the device ensures stable energy release during the micro-splitting test, making the micro-wedge splitting test device suitable for testing the fracture performance of small-sized functional components.
Owner:WUHAN UNIV OF SCI & TECH +1

Compound drink with functions of clearing away lung heat, moistening lung, diminishing inflammation and resisting bacteria and preparation process thereof

PendingCN119404996Arelease stabilityGood antibacterial and anti-inflammatory effectNatural extract food ingredientsFood ingredient functionsBiotechnologyFruit juice
The invention relates to the field of drinks, and particularly discloses a compound drink with functions of clearing away the lung heat, moistening the lung, diminishing inflammation and resisting bacteria and a preparation process of the compound drink. The invention relates to a compound drink with lung-heat-clearing, lung-moistening, inflammation-diminishing and antibacterial functions. Comprising the following raw materials in parts by weight: 70-90 parts of elderberry concentrated juice, 30-50 parts of Pesson berry powder, 8-12 parts of Laiyang pear syrup, 20-30 parts of acerola cherry powder, 6-10 parts of sophora flower bud composite microcapsules, 18-24 parts of roxburgh rose original juice, 0.1-0.3 part of roxburgh rose powder, 0.1-0.3 part of phyllanthus emblica powder, 0.1-0.3 part of mulberry powder, 0.1-0.3 part of spirulina platensis powder and the balance of purified water. The pagodatree flower bud composite microcapsule is prepared by wrapping a pagodatree flower bud extract and pagodatree flower bud powder with a water-soluble wall material. The compound drink has the effects of clearing away the lung-heat, moistening the lung, diminishing inflammation and resisting bacteria, and has good taste and stability.
Owner:DR DODO HEALTH TECH (HANGZHOU) CO LTD

A controlled-release polyferric sulfate water treatment agent and its preparation method

The present invention discloses a controlled-release type polymeric ferric sulfate water treatment agent and its preparation method, belonging to the technical field of water treatment functional materials. The water treatment agent consists of polymeric ferric sulfate, an iron ion color indicator, a gel matrix, a cross-linking calcium agent, amino diatomaceous earth, a pore-forming agent and an inert filler. The preparation method includes: first preparing a network gel, then preparing soft materials, and finally obtaining the product through pill-making and drying. The present invention realizes the slow release and controllability of polymeric ferric sulfate, and the color indicator can directly reflect the consumption state of polymeric ferric sulfate, facilitating storage, transportation, dosing and recovery.
Owner:XUZHOU FANGWEI ENVIRONMENTAL PROTECTION TECH CO LTD

A multi-modal perception-based organic agricultural product consumption scene dynamic adaptation method and system

This invention discloses a dynamic adaptation method for organic agricultural product consumption scenarios based on multimodal perception. The method is executed by an edge server in the exhibition hall and includes: receiving a display collaboration request sent by a mobile terminal; determining a target video based on the source identifier of the streaming media content and product information; determining whether multiple public display terminals are available; and if a first public display terminal is determined to be available, sending the target video to the first public display terminal for playback and sending the terminal identifier of the first public display terminal to the mobile terminal to notify the user of the first public display terminal. This invention can improve the collaborative display efficiency between mobile streaming media content and public display resources in organic agricultural product exhibition halls and enhance the dynamic adaptation effect in agricultural product consumption scenarios.
Owner:HARBIN UNIV OF COMMERCE

Semiconductor constant-temperature wine decanter

The utility model discloses a kind of semiconductor constant-temperature wine decanter, belong to wine decanter technical field, including wine storage shell, its inside is provided with wine storage heat preservation groove, wine storage heat preservation groove bottom is provided with temperature-guiding cold aluminium seat, the cold end of semiconductor refrigeration sheet is abutted in temperature-guiding cold aluminium seat, the hot end of semiconductor refrigeration sheet is abutted on radiating fin, radiating fin is connected in fan cover, fan cover is provided with radiating fan, wine storage shell bottom is provided with a plurality of first radiating holes, radiating fan is towards a plurality of first radiating holes, wine storage shell bottom is provided with support seat. The utility model utilizes semiconductor refrigeration sheet to combine wine storage heat preservation groove, ensure that internal temperature is constant and is not affected, this structure will wine bottle be placed in wine storage heat preservation groove, guarantee the constant temperature of wine in bottle, so that under constant-temperature environment, volatile speed of aroma molecule is relatively stable, can make grape wine continuously, stably release various aroma, improve drinking experience.
Owner:SHENZHEN HUAHAI THERMAL POWER CO LTD

Antifouling alloy, method for producing the same, and antifouling sheet produced from the same

The application relates to a scale-inhibiting alloy and a preparation method thereof and a scale-inhibiting sheet manufactured from the scale-inhibiting alloy. The scale-inhibiting alloy comprises the following components: 55wt%-70wt% of Cu, 15wt%-30wt% of Zn, 5wt%-15wt% of Ni, 0.5wt%-3wt% of Si, 1wt%-5wt% of P, 0.001wt%-0.05wt% of a modifying element, and the balance of inevitable impurities, wherein the modifying element is one or more of B, Ti and Zr. The scale-inhibiting alloy adds the Si element for strengthening, so as to improve the mechanical properties and corrosion resistance; the Zn element is added as a negative electrode and the P element is added as a positive electrode, the alloying forms alpha phase+beta phase+multi-element brittle compound phase, can well excite the active current, and prevents the generation of water scale. The scale-inhibiting alloy has low production cost, meets the comprehensive requirements of cost, processing performance, corrosion resistance, mechanical properties, health and market acceptance of water treatment products, and has a good application prospect.
Owner:JOMOO KITCHEN & BATHROOM

Nasal cavity coated drug-loaded stent and preparation method thereof

The invention discloses a nasal cavity coated drug-loaded stent and a preparation method thereof, and relates to the technical field of nasal cavity stents.The coated drug-loaded stent comprises a coated drug-loaded stent body and a drug coating covering the surface of the coated stent body, and the drug coating comprises a therapeutic drug and a carrier thereof; the carrier comprises a first polymer and a second polymer which have different drug loading functions; and a tissue regeneration guide layer can also be arranged on the medicine coating. The coated drug-loaded stent provided by the invention not only has a large wound surface contact area, but also can effectively regulate and control the drug release period, so that the drug release during the wound surface repair period is more stable, long-acting and controllable, thereby meeting the needs of nasal cavity wound surface repair.
Owner:NUOYIMEIER (SHANDONG) MEDICAL TECH CO LTD +1

Zinc acrylate resin, tin-free self-polishing antifouling paint containing zinc acrylate resin and preparation method of zinc acrylate resin

The invention provides zinc acrylate resin, a tin-free self-polishing antifouling coating containing the zinc acrylate resin and a preparation method of the zinc acrylate resin, and belongs to the technical field of coatings. The preparation method comprises the following steps: mixing the zinc acrylate resin, the rosin, the antifouling agent, the iron oxide red, the talcum powder, the auxiliary agent and the xylene according to the formula ratio, stirring for 2-4 hours at the speed of 1000-1200 r / min, and grinding until the fineness is 1t; the thickness is 100 microns, so that the tin-free self-polishing antifouling paint is prepared. The tin-free self-polishing antifouling paint prepared by the invention has good mechanical properties, flexibility, oxidation resistance, aging resistance, antifouling effect, stable bactericide release and excellent self-polishing effect, has excellent antifouling effect in the advancing process of a ship and in still water, has small harm to the environment, has stable antifouling agent release rate, and can be widely applied to the fields of ships, ships and the like. And the antifouling period is prolonged.
Owner:GUANGDONG WEIQI NEW MATERIAL TECH CO LTD

Rotary structure for packing a box

ActiveCN224739694Urelease stabilityreliable release
This utility model relates to a rotating structure for box packaging, comprising a circular track ring mounted on a side plate, a circular rotating ring rotatably mounted on the circular track ring, a tape holder assembly mounted on the circular rotating ring for mounting a tape roll, and a first drive unit mounted on the side plate for driving the circular rotating ring to rotate. By employing the first drive unit to make the circular rotating ring rotate on the circular track ring, the stability and reliability of the tape holder assembly on the circular rotating ring during tape release can be ensured.
Owner:CHANGSHU YOUMU INTELLIGENT TECH CO LTD

A sensitizing film for radioactive stent and preparation method thereof

The present invention discloses a sensitizing film for radioactive stents and a preparation method thereof, aiming to overcome the existing radiotherapy stents' great damage to normal tissues and the shortcomings of traditional sensitizing drug coating materials. The sensitizing film for radioactive stents includes a first film layer and a second film layer, wherein the first film layer is a polyurethane support layer, and the second film layer contains a radiosensitizing drug component; the platinum radiosensitizing drug is oxidized to a tetravalent platinum drug, a polyarginine targeting group is introduced for modification, and then PLGA50:50 with a molecular weight of 5k is used for modification; the first film layer composed of polyurethane and the second film layer composed of PLGA75:25 with a molecular weight of 100k and containing a radiosensitizing drug component are prepared by electrospinning technology. The sensitizing film for radioactive stents of the present invention has the advantages of high targeting, low toxicity and side effects, high efficiency sensitization, good support, sustained release, and simple and efficient preparation process, providing a new, safe and effective treatment method for the field of intracavitary tumor radiotherapy.
Owner:UNION BIOTECH TIANJIN

A stress-tolerant quality-improving plant growth regulator composition for rice and a preparation method thereof

PendingCN122785644AImprove seed setting rateIncrease thousand grain weight
This invention discloses a plant growth regulator composition for improving rice quality and resistance to stress, and its preparation method. It relates to the fields of plant growth regulators and agricultural stress-resistant cultivation technology. The plant growth regulator composition is a water-dispersible granule or wettable powder, comprising, by weight percentage: 0.05%-0.30% 5-aminolevulinic acid, 1.0%-5.0% γ-aminobutyric acid, 8.0%-20.0% betaine, 3.0%-10.0% trehalose, 2.0%-8.0% chitosan oligosaccharide, 1.0%-5.0% fucoidan oligosaccharide, and salicylic acid or its agricultural grade. Acceptable components include 0.05%–0.50% salt, 20.0%–45.0% potassium dihydrogen phosphate, 3.0%–15.0% water-dispersible silica, 0.5%–3.0% amino acid chelated zinc, 3.0%–10.0% magnesium sulfate, 0.5%–3.0% wetting and dispersing agent, 1.0%–6.0% binder, with the balance being water-soluble filler. Porous water-dispersible silica is used as a carrier to allow sensitive active substances such as 5-aminolevulinate and salicylic acid to enter the carrier pores and be immobilized in the protective matrix formed by chitosan oligosaccharide and trehalose.
Owner:HAINAN TSUEN YIN FIVE STAR SEED IND CO LTD

Traditional Chinese medicine composition and traditional Chinese medicine glasses frame

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition and a traditional Chinese medicine glasses frame. 10 to 20 parts of rhizoma acori graminei; 10 to 20 parts of polygala tenuifolia; 20 to 30 parts of menthol; 5-10 parts of clove; 10 to 15 parts of borneol; 10 to 20 parts of Chinese angelica; 10 to 20 parts of radix astragali seu hedysari; 5-10 parts of cassia oil; 10 to 20 parts of poria cocos; the traditional Chinese medicine composition fully embodies the compatibility principle of monarch, minister, assistant and guide. Ligusticum wallichii is used as monarch for promoting blood circulation to remove blood stasis; the rhizoma acori graminei and the polygala tenuifolia are used as minister Menthol, clove and borneol are used as assistants to enhance the drug effect; angelica sinensis and astragalus membranaceus are used as guide drugs to tonify qi and nourish blood. The combination not only can improve local symptoms, but also can regulate body functions on the whole, and embodies the thought of overall view and treatment based on syndrome differentiation of traditional Chinese medicine.
Owner:江鸿特材科技(深圳)有限公司

Slow-release material with antibacterial property and preparation method thereof

The invention discloses a sustained-release material with an antibacterial property and a preparation method of the sustained-release material. The sustained-release material is composed of a core component group: ZIF-8, modification component groups: Co < 2 + > and Ni < 2 + >, a composite component group: sodium alginate and a loading component group: tetracycline. The preparation method comprises the following steps: synthesizing a ZIF-8 skeleton through a hydrothermal method, and performing Co < 2 + > and Ni < 2 + > surface modification; then, sodium alginate is used for composite treatment, and tetracycline is loaded into the material. The structure of the material is easy to collapse in an acid environment, and drug release is accelerated; the structure is relatively stable in a weakly alkaline environment, and a slow-release effect is realized. Compared with a traditional antibacterial material, the antibacterial material has the advantages of being high in antibacterial property, good in slow release property, high in biocompatibility and the like, the preparation process is simple, and the antibacterial material is suitable for large-scale production.
Owner:翟紫薇

Intelligent remote control cement head

The invention discloses an intelligent remote control cement head, and belongs to the technical field of well cementation. A rubber plug baffle assembly and a rotary stop pin assembly are arranged in the middle of the cement pipe body, when the rubber plug baffle assembly is in a closed state, an inner cavity of the cement pipe body is divided into an upper cavity and a lower cavity which are not communicated through the rubber plug baffle assembly, the upper cavity is used for containing a rubber plug, and the rubber plug is located above the rubber plug baffle assembly in the closed state. The rotary stop pin assembly is used for keeping the rubber plug baffle assembly in a closed state; an F-shaped high-pressure manifold is arranged on the right side of the cement pipe main body; an L-shaped high-pressure manifold is arranged on the left side of the cement pipe body. The valve is reasonable and compact in structure and convenient to use, the stop block is driven by the movable valve element to turn over, the stop block relieves limiting of the end of the transverse partition plate, the transverse partition plate can turn over clockwise to enter the containing cavity, and therefore the rubber plug can be stably released; and the overturning state of the hexagon nut can be monitored through the sensor, so that an operator can accurately judge the release condition of the rubber plug.
Owner:JIANGSU HUARISHENG OIL & GAS WELL TOOLS CO LTD

Traditional Chinese medicine composition and application thereof

The invention discloses a traditional Chinese medicine composition and application thereof. Relates to the technical field. The invention provides application of the traditional Chinese medicine composition, an astragalus membranaceus and cassia twig five-material decoction extracted concentrated solution, an astragalus membranaceus and cassia twig five-material decoction nanoemulsion, an astragalus membranaceus and cassia twig five-material decoction gel plaster and the like. Aiming at the active ingredients of the optimized traditional Chinese medicine composition, the invention develops a nano-emulsion gel plaster preparation for relieving diseases such as muscle pain and rheumatic arthritis. The O / W nano-emulsion technology is used for achieving efficient loading of hydrophilic and hydrophobic functional substances in the radix astragali and cassia twig five-material decoction and the skin penetrating capacity of the hydrophilic and hydrophobic functional substances in the radix astragali and cassia twig five-material decoction. The nanoemulsion is uniformly dispersed in a three-dimensional network structure formed by absorption and swelling of polyacrylic acid, so that the medicine can be slowly and stably released, and the phenomenon of unstable crystallization caused by thermodynamic movement of supersaturated medicine molecules can be hindered. In addition, the gel plaster has a good moisturizing effect and is good in skin attaching feeling and excellent in swelling performance and thixotropic performance.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI +1

Anti-seismic connecting structure of assembly type anti-radiation shielding building body

The invention relates to the field of fabricated buildings. The invention aims to provide an anti-seismic connecting structure of an assembly type anti-radiation shielding building body. The anti-seismic connecting structure comprises a rectangular base laid in a foundation pit and an assembly building body arranged on the base. The assembly building main body comprises a main body frame and an assembly shielding plate; the main body frame comprises stand columns, a bottom beam and a top beam, and the stand columns are arranged at the four corners of the base and connected with the base through anti-seismic buffer seats; the anti-seismic buffer seat comprises a connecting square table fixedly arranged on the top face of the corner of the base, a square column cavity is formed in the lower end of the stand column, and the stand column is arranged outside the connecting square table in a sleeving mode through the column cavity. The anti-seismic shielding room can effectively buffer the shearing effect of seismic shock waves on a building, and the anti-seismic performance of the shielding room is guaranteed.
Owner:SICHUAN SHANLI CONSTR TECH CO LTD

Capsule type metal catalyst as well as preparation method and application thereof

The invention provides a capsule type metal catalyst and a preparation method and application thereof, and the preparation method comprises the following steps: (1) preparing a sodium carboxymethyl cellulose aqueous solution with a certain concentration, adding an additive and a metal salt solution, and uniformly dispersing to obtain a mixed solution A; (2) preparing a gelatin aqueous solution with a certain concentration, then uniformly mixing the gelatin aqueous solution with the mixed solution A, adjusting the pH value of the solution to be acidic, and continuing the reaction to obtain a mixed solution B; (3) placing the obtained mixed solution B in an ice-water bath, and adding a curing agent to carry out a cross-linking curing reaction to obtain a material C; and (4) washing and drying the material C to obtain the capsule type metal catalyst. The capsule type metal catalyst prepared by the invention is applied to hydrosilylation reaction, and can realize high reactant conversion rate and high target product selectivity under mild reaction conditions.
Owner:YUNNAN PRECIOUS METALS LAB CO LTD +1

Attached auricular point treatment patch and preparation method thereof

The invention discloses an attached auricular point treatment patch and a preparation method thereof, and particularly relates to the technical field of medical devices, the attached auricular point treatment patch comprises a core medicine layer, a protective isolation layer and a fixing layer, the core medicine layer is covered with the protective isolation layer, and the fixing layer is attached to the other side of the protective isolation layer; the core medicine layer is prepared from the following raw materials in parts by weight: 5 to 20 parts of radix angelicae sinensis, 5 to 15 parts of radix achyranthis bidentatae, 3 to 10 parts of rhizoma gastrodiae, 3 to 8 parts of rhizoma atractylodis macrocephalae, 1 to 5 parts of radix ginseng, 2 to 6 parts of rhizoma chuanxiong, 0.5 to 3 parts of nano folium ginkgo extract, 0.5 to 2 parts of radix astragali seu hedysari extract, a viscous matrix accounting for 5 to 20 percent of the total weight and a penetration enhancer accounting for 1 to 5 percent of the total weight; and the protective isolation layer is made of a medical grade polyethylene or polypropylene film with the thickness of 0.01-0.06 mm. The auricular point treatment patch can stably and continuously release medicine and effectively permeate into auricular points to achieve a good treatment effect, meanwhile, the solubility and bioavailability of the medicine are remarkably improved, the treatment effect is enhanced, and the comfort level and the fitting degree are good.
Owner:GUANGDONG SECOND TRADITIONAL CHINESE MEDICINE HOSPITAL (GUANGDONG PROVINCE ENG TECH RES INST OF TCM)