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The present invention is directed to a system and method for providing real-time position information of one party to another party by utilizing a conventional telecommunication network system such as the convention telephone network, a mobile telecommunications network, a computer network, or the Internet. More specifically, the preferred embodiments of the present invention allow a caller and a receiver of a telephone call to provide to and receive from each other position information related to the caller and / or receiver's physical location, including address information, GPS coordinates, nearby fixed locations such as a parking structure, etc. Additionally, the preferred embodiments of the present invention allow a caller and receiver to retrieve routing instructions or maps for traveling to or from each other. In another embodiment of the present invention, a party may locate the position of another party via the entry of the other party's unique identifier such as a phone number of the other party's mobile phone. In yet another embodiment of the present invention, the position information of a party may be concurrently delivered to another party's computer terminal whereby the other party can process the information in further detail.

An apparatus for interspinous spinal fixation is disclosed, which includes a main body having an end thereof as a distal end, and another end thereof as a proximal end, a cross section of the main body being of an annular or quasi-annular structure. A first joining point and a second joining point are provided at the distal end that are symmetric to each other relative to an opening of the annular or quasi-annular structure, while a third joining point and a fourth joining point are provided at the proximal end that that are symmetric to each other relative to the opening of the annular or quasi-annular structure. A first lateral piece, a second lateral piece, a third lateral piece, and a fourth lateral piece are joined with the first, the second, the third, and the fourth joining points of the main body, such that the first and the second lateral pieces can rotate axially about the first and the second joining points, thereby rotating from a folded position on the main body to an extended position; and the third and the fourth lateral pieces can rotate axially about the third and the fourth joining points, thereby rotating from a folded position on the main body to an extended position.

A method of path planning, comprising providing a dataset representing a cavity and a boundary; providing a plurality of points in said dataset, including at least a starting point and an ending point; and automatically determining a path between the starting point and the ending point, responsive to a penalty associated with passing through points in the cavity. Preferably, the penalty value associated with a point depends on a distance between the point and the boundary.

A card game wherein a player has the choice of playing the player's initial hand of cards as either a poker hand or a modified blackjack hand. If the player elects to play the hand as a poker hand, the player will win if he or she acquires a poker hand that matches one of a plurality of predetermined poker hands. If the player elects to play the hand as modified blackjack hand, the player wins if the player acquires a hand that qualifies as a winning hand. If the player wins, the player has the option of playing the dealer in a second type of card game wherein the player has the option of wagering all of his or her winnings (“Double Down”) or wagering only half of his or her own winnings (“Half Down”).

Compositions and methods are provided for preparing a metal substrate having a uniform textured surface with a plurality of indentations with a diameter in the nanometer and micrometer range. The textured surface is produced by exposing the substrate to an etching fluid comprising a hydrohalic acid and a mixture of a hydrohalic acid and an oxyacid, a chloride containing compound, and an oxidant. The etching solution can be used at ambient temperature. This textured surface enhances adherence of coatings or cells onto the textured surface, improves the retention of proteins on the surface, and encourages bone in-growth.

A system and method for imaging of a sample, e.g., biological sample, are provided. In particular, at least one source electro-magnetic radiation forwarded to the sample and a reference may be generated. A plurality of detectors may be used, at least one of the detectors capable of detecting a signal associated with a combination of at least one first electro-magnetic radiation received from the sample and at least one second electro-magnetic radiation received from the reference. At least one particular detector may have a particular electrical integration time, and can receive at least a portion of the signal for a time duration which has a first portion with a first power level greater than a predetermined threshold and a second portion immediately preceding or following the first portion. The second portion may have a second power level that is less than the predetermined threshold, and extends for a time period which may be, e.g., approximately more than 10% of the particular electrical integration time.

Selective occlusion of a blood vessel is achieved by selectively damaging endothelial cells at a target location in the blood vessel, resulting in the formation of a fibrin clot proximate to the damaged endothelial cells. Additional fibrinogen can then be introduced into the blood vessel if occlusion is not achieved, as the fibrinogen is converted to fibrin by enzymes released by the exposed thrombogenic tissue and activated platelets. Endothelial cells are selectively damaged using thermal effects induced by ultrasound, by mechanical effects induced by ultrasound, or by mechanical effects produced by a tool introduced into the blood vessel (such as a catheter-based tool). A particularly preferred technique for selectively damaging endothelial cells involves introducing an ultrasound activatable agent into the blood vessel, and causing cavitation in that agent using pulses of high-intensity focused ultrasound having a duration insufficient to induce thermal damage in adjacent perivascular tissue.

To store an input string of M N-tuples of bits, a substitution transformation is selected in accordance with the input string and is applied to the input string to provide a transformed string of M N-tuples of bits. M or more memory cells are programmed to represent the transformed string and preferably also to represent a key of the transformation. Alternatively, the memory selectively programs each of M or more cells to a respective one of 2N states. A mapping that maps the binary numbers in [0,2N−1] into respective states is selected in accordance with the input string and is used to program M cells to represent the input string. Preferably, a key of the mapping is stored in the memory in association with the M cells.

A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate. The method can be used to deliver a therapeutic polypeptide to the cells of the vertebrate, to provide an immune response upon in vivo translation of the polynucleotide, to deliver antisense polynucleotides, to deliver receptors to the cells of the vertebrate, or to provide transitory gene therapy.

Compositions and methods are provided for preparing a metal substrate having a uniform textured surface with a plurality of indentations with a diameter in the nanometer and micrometer range. The textured surface is produced by exposing the substrate to an etching fluid comprising a hydrogen halide acid and / or an oxyacid, a chloride containing compound, and an oxidizing agent. The etching solution can be used at ambient temperature without damaging the metal elements on the substrate surface. This textured surface enhances adherence of coatings or cells onto the textured surface, improves the retention of proteins on the surface, and encourages bone in-growth.