The invention discloses real-time imaging skin diagnosis equipment by optical coherence tomography, and belongs to the field of optical imaging equipment. The equipment comprises a power supply, a light source control circuit, a light source, an indicating light source, a first optical fiber coupler, a second optical fiber coupler, an OCT probe, an optical delay line, a photo detector, a signal processing and control circuit, and a computation processing and display device. The imaging equipment takes the optical coherence tomography (OCT probe) as a core, processes signals rapidly by the signal processing and control circuit, and improves the imaging speed and image resolution by cooperating with the computation processing and display device; designs of a wideband light source and a duckbill-shaped probe applicable to skin scanning cause the equipment to be applicable to scanning human skin, and real-time and rapid imaging can be realized by cooperation of the signal processing and control circuit with the computation processing and display device.