222 results about "Hydrogel composite" patented technology

The invention relates to a functional liquid metal-based temperature-responsive hydrogel material and a preparation method thereof, and belongs to the technical field of functional polymer hydrogel materials.The preparation method comprises the following steps that a temperature-responsive hydrogel composite material comprises a hydrophobic association polymer gel and a hydrogel monomer, the hydrophobic association polymer gel comprises a hydrophobic association polymer monomer, a functional filler and an initiator. The functional filler is liquid metal gallium with the edge modified by graphene oxide, and has triple functions: firstly, the functional filler is used as an electrostatic crosslinking node to form a crosslinking network with anionic ionic liquid; secondly, dynamic repair is promoted, and Ga < 3 + > is released to promote dynamic bond recombination. In addition, as a functional filler, the hydrogel is endowed with excellent photo-thermal and electro-thermal conversion performance, and the multi-stimulus response capability is enhanced. The composite material realizes structural assembly by means of hydrophobic association, shows reversible phase change and repeated self-assembly characteristics under various stimuli such as photo-thermal, electric heating, direct heating and the like, and has wide application potential.

The invention discloses a super-smooth, anti-corrosion and anti-coagulation hydrogel composite coating on the surface of a medical instrument as well as a preparation method and application of the super-smooth, anti-corrosion and anti-coagulation hydrogel composite coating, and the super-smooth, anti-corrosion and anti-coagulation hydrogel composite coating is a surface hydrogel composite coating formed by taking N-(3, 4-dihydroxyphenethyl)-2-benzoylbenzamide (BPDA) as a primer and grafting a hydrophilic polymer on the primer. BPDA is deposited on the surface of the substrate, then hydrophilic monomer surface graft polymerization is initiated by light, and a hydrogel coating is constructed on the surface of the BPDA substrate. The BPDA primer provides excellent corrosion resistance, the corrosion rate of a metal substrate is effectively reduced, and benzophenone derivatives with photoreaction activity on BPDA molecules can mediate firm combination of the hydrogel layer; after meeting water, a stable and compact hydrated layer is formed, the super-lubricating property is achieved, adhesion of protein and cells can be remarkably inhibited, and thrombus formation is effectively prevented. The anti-corrosion and anti-blood coagulation coating has excellent anti-corrosion and anti-blood coagulation properties, and is widely applicable to anti-blood coagulation and anti-corrosion surface modification in the fields of medical instruments and the like.

The application discloses a kind of imitated plant leaf hydrogel composite material and preparation method thereof, belong to bionic composite material field.The application first by colorant compounding preparation printing paste, and fabric is printed, obtain the green fabric that can realize to plant leaf " green peak " and " red edge " spectral characteristic simulation, and with green fabric simulation leaf structure in fence organization and skeleton;Then with biomaterial polyvinyl alcohol (PVA) as base material, join with strong hygroscopic monomer and crosslinking agent, initiator blend preparation hydrogel prepolymer solution;Finally, hydrogel prepolymer solution is poured into the mold containing green fabric and copolymerization, it directly forms hydrogel in fabric surface and pore interior, obtains imitated plant leaf hydrogel composite material.The material gets rid of the dependence on hygroscopic salt, has water absorption and simulation effect stable, durability is good and the like advantages.

The invention provides a medical implant, a preparation method thereof and an artificial knee joint. The medical implant comprises a macromolecular porous stent and a hydrogel composite material at least filled in pores of the macromolecular porous stent, and the material of the macromolecular porous stent comprises a degradable macromolecular material and carbon nanotubes distributed in the degradable macromolecular material. The hydrogel composite material comprises a hydrogel material matrix and seed cells distributed in the hydrogel material matrix. According to the invention, the degradable high polymer material and the hydrogel material are combined, the carbon nanotubes are introduced into the degradable high polymer material, and meanwhile, seed cells are arranged in a hydrogel material matrix, so that the implantable stent material which has proper degradation performance and good mechanical properties and is renewable is provided.

The invention provides a preparation method and application of a polyacrylamide / carboxylated chitosan / ionic liquid (PAM / CCS / ionic liquid) hydrogel composite material, and belongs to the technical field of hydrogel materials. Dispersion liquid of ionic liquid, carboxylated chitosan, acrylamide and zinc salt is subjected to polymerization reaction under the condition that an initiator and a cross-linking agent are added, and then the PAM / CCS / ionic liquid hydrogel composite material is prepared in situ. The preparation method provided by the invention is simple and efficient, and the obtained PAM / CCS / ionic liquid hydrogel composite material has high ionic conductivity, excellent mechanical properties and wider applicable temperature range. When the PAM / CCS / ionic liquid hydrogel composite material prepared by the method provided by the invention is used as a gel electrolyte of a zinc storage device, excellent electrochemical performance is shown.

The invention belongs to the technical field of biological medicines, and particularly relates to nasal temperature-sensitive hydrogel with immunoregulation and anti-inflammatory functions as well as a preparation method and application of the nasal temperature-sensitive hydrogel. The preparation method of the nasal temperature-sensitive hydrogel with the immunoregulation and anti-inflammatory functions comprises the following steps: preparation of hydroxybutyl chitosan (HBC), preparation of levodopa-hydroxybutyl chitosan (LHBC), and preparation of CELHBC composite hydrogel. The novel temperature-sensitive hydrogel composite material of the composite hydrogel loaded with the chlorella / exosome can be used for the focus position of allergic rhinitis, and enrichment and retention of active ingredients are achieved; the chlorella is combined with the exosome, so that the inflammatory response of nasal mucosa can be relieved, the damaged nasal mucosa can be repaired, and the immune imbalance of Th1 / Th2 cells can be reversed, thereby improving the treatment effect of allergic rhinitis.

The application provides a thermoelectric hydrogel composite dressing for promoting repair of diabetic ulcers and loading of targeted modified exosomes and a preparation method, which comprises the following steps: preparing methacrylated hyaluronic acid; preparing polyether F127 diacrylate; co-incubating exosomes with palmitic acid grafted targeting peptides to prepare targeted modified exosomes; mixing the methacrylated hyaluronic acid, the polyether F127 diacrylate, a photosensitizer, the targeted modified exosomes and an electrolyte, and crosslinking under ultraviolet light to form a composite gel. The composite dressing is a novel composite dressing for thermoelectric stimulation and exosome treatment. On one hand, the dressing generates a wireless and passive electric field to simulate the endogenous electric field in the wound, promote directional migration of skin cells, accelerate reepithelialization and dermal formation; on the other hand, the dressing releases exosomes to precisely target blood vessels of a wound lesion, reverse endothelial dysfunction in a high-sugar environment and promote angiogenesis, and effectively solves the problems in repair and regeneration of diabetic ulcer wounds.

The invention discloses a photo-thermal hydrogel sponge with excellent salt resistance and a preparation method and application thereof, and belongs to the technical field of solar evaporators. The preparation method comprises the following steps: firstly, preparing melamine sponge (MS) with an asymmetric structure, filling a prepared polyacrylamide / graphene oxide (PAM / GO) hydrogel precursor solution and a prepared polyacrylamide / polyquaternium-7 (PAM / PQ7) hydrogel precursor solution into the melamine sponge by adopting a method of combining entering and injection, and preparing the polyacrylamide / polyquaternium-7 / PAM / PQ7 hydrogel composite material. The Janus structure photo-thermal hydrogel sponge with excellent salt resistance is obtained. The evaporator adopting the photo-thermal hydrogel sponge has an automatic salt resistance characteristic and an efficient salt resistance performance.

The invention discloses piezoelectric electrospinning rod compounded collagen-based hydrogel as well as a preparation method and application thereof, and belongs to the field of piezoelectric biological materials. Carrying out electrospinning on polyhydroxybutyrate through an electrospinning technology to prepare piezoelectric oriented fibers loaded with piezoelectric ceramics; preparing the piezoelectric oriented fiber into a piezoelectric electrospinning rod by using a freezing slicing technology; collagen and chitosan are cross-linked by using a biological cross-linking agent to form collagen-based hydrogel; and compounding the piezoelectric electrospinning rod in the collagen-based hydrogel to prepare the collagen-based hydrogel compounded by the piezoelectric electrospinning rod. The hydrogel prepared by the invention has good piezoelectric property, better mechanical property and excellent biocompatibility, and can well meet the requirement of an endogenous electric field at a cartilage defect.

The invention relates to the technical field of composite material preparation, in particular to a preparation method of a polymer film / hydrogel composite material with a wrinkled surface. The preparation method of the polymer film / hydrogel composite material with the wrinkled surface comprises the steps that hydrogel comprises a first surface and a second surface which are oppositely arranged, the first surface adheres to a substrate, the second surface is coated with a polymer solution, and the polymer film / hydrogel composite material is obtained through light curing treatment and drying treatment in sequence; and soaking the polymer film / hydrogel composite material in water to obtain the polymer film / hydrogel composite material. By controlling the raw materials, the hydrogel thickness, the soaking treatment time and the like, the fold wavelength and amplitude of the polymer film / hydrogel composite material can be accurately regulated and controlled, and the requirements of different application scenes can be met.

The invention belongs to the field of medical dressing materials, and particularly relates to a metal organic framework / hydrogel composite material and a method and application thereof. The hydrogel composite material contains hydrogel and a metal organic framework, and the hydrogel composite material has a hybrid structure formed by mutual intersection of the hydrogel and the metal organic framework. The preparation method of the hydrogel composite material comprises the following step: carrying out coordination reaction on a solution containing metal ions, small molecular ligands and hydrogel to obtain the hydrogel composite material. The hydrogel composite material has the flexibility of the hydrogel and the mechanical strength and long-acting antibacterial property of the metal organic framework, the hydrogel and the MOFs are compounded to organically combine a flexible material and a rigid material, the performance of the hydrogel and the performance of the MOFs are improved, and the application value of the hydrogel composite material in the medical field is expanded. In practical application, the hydrogel has the advantages of promoting wound healing, resisting bacteria and having biocompatibility.

The invention belongs to the technical field of conductive hydrogel composite materials, and relates to nanofiber reinforced composite organic hydrogel as well as a preparation method and application thereof.The method comprises the following preparation steps: synthesizing a thermoplastic polyurethane (TPU) nanofiber membrane in advance, uniformly filling a TPU stretchable matrix with carbon nanotubes (CNTs) in a solvent by adopting ultrasonic assistance, and preparing the nanofiber reinforced composite organic hydrogel. A conductive network is adjusted by adjusting the loading capacity of carbon nanotubes on a fiber membrane through different ultrasonic time, and the upper layer and the lower layer of the modified fiber membrane are coated with a polyvinyl alcohol / glycerol / aqueous solution to prepare a conductive CNTs (at) TPU-X nanofiber membrane (x is ultrasonic time), so that the elastomer film sensor with a sandwich-like structure is obtained. According to the invention, the problems of dispersibility of the nanofiller in a hydrogel matrix and interfacial compatibility of fibers and gel are solved.

The invention provides a natural Chinese herbal medicine hydrogel composite microneedle and a preparation method and application thereof.The preparation method comprises the steps that S1, natural food-borne nutrients and glycyrrhizic acid are mixed in a solvent, and a glycyrrhizic acid / natural food-borne nutrient solution is obtained; the natural food-borne nutrient is one or more of astaxanthin, baicalein, berberine and curcumin; s2, dropwise adding a metal salt solution into the glycyrrhizic acid / natural food-borne nutrient solution, and performing ultrasonic treatment and stirring to obtain glycyrrhizic acid / food-borne active substance gel; s3, mixing the polyanionic polymer solution with the glycyrrhizic acid / food-borne active substance gel to obtain a mixed solution; and S4, adding the mixed solution into a microneedle mold, carrying out vacuum centrifugation, and drying to obtain the microneedle patch. Good biocompatibility of the natural Chinese herbal medicine extract glycyrrhizic acid is used as a carrier to increase the in-vivo utilization rate of natural food-borne nutrients, so that a better treatment effect is achieved.

The present invention relates to the field of medical repair materials and particularly to a double-crosslinked hydrogel composite material, a preparation method therefor, and use thereof. The double-crosslinked hydrogel composite material comprises a physical-chemical double-crosslinked copolymer formed by reacting at least one type of acrylic monomer and at least one type of zwitterionic monomer in the presence of nanoparticles and a crosslinking agent. The double-crosslinked hydrogel composite material of the present invention has the characteristics of high mechanical strength, high adhesion strength, and swelling resistance, is low in cost, and features a preparation process that is simple and rapid and easy to regulate. Therefore, the material has very high application value.

The invention discloses a hydrogel composite material for repairing acute kidney injury as well as preparation and application thereof. The hydrogel composite material for repairing the acute kidney injury comprises peroxisome serving as an oxidative stress regulation center and self-assembly repairing polypeptide gel for encapsulating the peroxisome. According to the composite material, oxidative stress regulation is carried out through a peroxisome cascade catalytic system, a polypeptide precursor solution is initiated to be self-assembled and polymerized into gel through pH responsiveness, local drug delivery is carried out, and cell repair regulation and control of kidney injury are achieved. The problem that oxidative stress and tissue damage are difficult to solve at the same time in existing single drug treatment is solved, wound healing is accelerated by rapidly neutralizing free radicals, reducing tissue damage, activating cell proliferation and regenerating related signal channels, the composition can act on damaged tissue more accurately, the influence on healthy cells is reduced, and due to the synergistic effect mechanism, the composition has a good application prospect. More efficient and targeted kidney repair can be realized, so that remarkable advantages are shown in the repair treatment of the acute kidney injury.

The invention provides a flexible stab-resistant composite material based on a three-dimensional angle interlocking fabric and a preparation method thereof, and relates to the technical field of composite materials, and the preparation method comprises the following steps: weaving the three-dimensional angle interlocking fabric with an interlayer oblique crossing angle interlocking structure; polyvinyl alcohol-sodium alginate hydrogel is prepared; the three-dimensional angle interlocking fabric is coated with the polyvinyl alcohol-sodium alginate hydrogel; and freezing and unfreezing the three-dimensional angle interlocking fabric coated with the polyvinyl alcohol-sodium alginate hydrogel to obtain the three-dimensional angle interlocking fabric-hydrogel composite material. The high-performance fiber three-dimensional angle interlocking fabric is used as a reinforcing body, the tough hydrogel is used as a flexible matrix, the protective performance of the stab-resistant material in a low-temperature environment is guaranteed, meanwhile, the stab-resistant material is endowed with multiple functions such as strain sensing and air and moisture permeability, and the balance of the protective effect, wearing comfort and multiple functions is achieved.

The invention provides hydrogel, a porous titanium / hydrogel composite implant material and a preparation method of the porous titanium / hydrogel composite implant material. The hydrogel is obtained by photo-crosslinking and curing a hydrogel precursor solution containing acrylated beta-cyclodextrin, acrylated alendronate sodium, gelatin and a chemotactic factor. The hydrogel has a porous network structure, high elastic modulus, high fatigue resistance and excellent biocompatibility, and also has the capability of recruiting bone marrow mesenchymal stem cells (BMSCs) and the capability of promoting osteogenic differentiation of the BMSCs; the porous titanium / hydrogel composite implant material prepared from the hydrogel can effectively promote the growth of new bone tissues, has excellent osseointegration capability, obviously improves the osteogenesis repair effect and the osseointegration effect, provides a new treatment approach for the repair treatment of segmental bone defects, and has important medical significance.

This invention discloses a method for preparing a biomimetic actuating material based on inkjet printing patterned construction of a reed inner membrane hydrogel composite. The method includes inkjet printing a reed inner membrane; adding N-isopropylacrylamide, N,N-methylenebisacrylamide, and 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylphenylacetone to an aqueous solution of nano-clay to obtain a hydrogel prepolymer; placing the inkjet-printed reed inner membrane on a glass slide, adding the hydrogel prepolymer, covering and sealing it, and then placing it in ice water for photopolymerization to obtain the reed inner membrane hydrogel composite biomimetic actuating material. This invention uses an inkjet printer to print pigment ink onto the surface of a natural reed inner membrane for patterning, and then rapidly forms a strong mechanical interlocking structure with poly(N-isopropylacrylamide) hydrogel, resulting in strong bonding. The method is simple, and the actuating material exhibits excellent photothermal conversion efficiency, mechanical properties, and patterning capabilities, thereby enabling rapid actuation, ultra-high power actuation, and various complex biomimetic actuator designs.

The invention relates to a textile-reinforced PVA-based hydrogel composite material with high elastic properties and strength that can be used in food, health, environment, textile sectors and wearable bioelectronic applications and its production method.

Some embodiments relate to a sustained release silica hydrogel composite comprising an anti-complement agent and methods of using same to treat ophthalmological conditions. The anti-complement agent may be an anti-C5 agent comprising a C5-specific aptamer.

The application discloses a preparation method and application of a novel LBL marine biomass hydrogel composite membrane. The preparation steps of the hydrogel composite membrane are as follows: adding chitosan quaternary ammonium salt into 0.1 M tris-hydrochloric acid solution to obtain chitosan quaternary ammonium salt solution through heating and stirring; adding sodium alginate into tris-hydrochloric acid solution to obtain sodium alginate solution through heating and stirring; taking an ultrafiltration membrane as a base film, spreading the chitosan quaternary ammonium salt solution on the surface of the base film first, pouring away the excessive solution after standing, and then spreading the sodium alginate solution on the chitosan quaternary ammonium salt solution after heat treatment in an oven, pouring away the excessive solution after standing, and heat treating in the oven to obtain a self-assembled hydrogel composite membrane. The layer-by-layer self-assembled hydrogel composite membrane is obtained through repeating the above process for multiple times. The preparation method is simple, the material is green and environment-friendly, the obtained membrane surface has superhydrophilicity, obvious separation efficiency is shown in dye wastewater treatment, and strong anti-pollution performance is shown.

The present invention relates to a method for manufacturing silica aerogel, which comprises: (1) manufacturing a hydrogel composite; (2) washing the manufactured hydrogel composite with a washing solvent; and (3) drying the washed hydrogel composite, wherein impurities are removed from the hydrogel composite in step (2), and the washing solvent is heated to a temperature above the boiling point (b.p.) of the washing solvent.

The invention belongs to the technical field of photonic crystal sensors, and relates to a photonic crystal sensor for tea polyphenol detection and a preparation method and application thereof. The preparation method comprises the following steps: synthesizing monodisperse CdS nano microspheres; the preparation method comprises the following steps: preparing CdS coated SiO2 core-shell nano microspheres; preparing a closely packed photonic crystal film; preparing a CdS coated SiO2 / hydrogel composite film structure; siO2 is etched, and a CdS / air / hydrogel thin film structure is prepared; and preparing the non-close packing photonic crystal sensor which takes the PNIPAm-co-AAPBA copolymer hydrogel as a matrix. The problems that an existing photonic crystal material is low in sensitivity and prone to being interfered by environmental factors, and consequently stability and accuracy are insufficient in a complex environment are solved.

The invention discloses a portable renewable cooling hydrogel composite material as well as a preparation method and application thereof. The portable renewable cooling hydrogel composite material comprises a three-dimensional network structure, porous solid particles and water, wherein the three-dimensional network structure is formed by cross-linking and curing macromolecules and an ionic cross-linking agent, and the porous solid particles are uniformly distributed in the three-dimensional network structure. The hydrogel composite material disclosed by the invention is beneficial to enhancing the diffuse reflection capability of sunlight, improving the optical reflectivity of the material and further improving the cooling performance, can be coated on a roof or other solid surfaces in situ without complex equipment during preparation, has good light reflectivity and evaporative cooling capability, can effectively reduce the surface temperature under sunlight, and is suitable for being used in the field of solar energy. The indoor cool feeling is kept; and after being dried, the composite material can be regenerated by spraying water, so that the composite material can be repeatedly used. The material is simple and convenient to prepare, low in cost and convenient to carry, and can be widely popularized in the fields of passive refrigeration, evaporative cooling, skin rehabilitation or building heat management and the like.

This invention relates to a dual-mode polycaprolactone (PCL) building energy-saving film and its preparation method. The dual-mode PCL building energy-saving film of this invention uses a temperature-sensitive PCL and hydrogel composite layer as the outer layer, and adds VO2-based materials. It can automatically reflect near-infrared light during high summer temperatures and automatically project sunlight during low winter temperatures; it requires no external power supply and is purely passively regulated. Furthermore, a PCL-based triboelectric nanogenerator array serves as the middle layer, which can collect mechanical energy from the building surface environment to power low-power sensors within the building, and can also connect surplus energy to the grid or store it. The transparent PCL and nanocellulose composite layer provides better mechanical support and is easy to install.

The present invention belongs to the technical field of medical materials, and particularly relates to an antibacterial and wound-healing promoting hydrogel composite dressing and a preparation method thereof. The composite dressing is obtained by mixing bacterial cellulose and a modified POSS material; the modified POSS material is obtained by grafting a polyol acrylate monomer with a reactive group in a POSS molecule through ultraviolet light initiation and then loading antibacterial nanoparticles on the surface. The composite dressing of the present invention is safe and non-toxic, further improves the antibacterial performance, mechanical strength and wound-healing promoting ability compared with traditional hydrogel dressings, can better relieve the pain of patients and accelerate the recovery process; and the preparation method is simple and controllable, and can be produced and applied on a large scale.

The invention relates to a macadamia nut flower and fruit retention synergistic method which comprises the following steps: in the early stage of flower bud differentiation, annularly applying slow-release granules to the root of a macadamia nut tree, and spraying fructan emulsion to the crown at the same time; in the early flowering period, a water dispersible sustained release preparation containing microencapsulated compound sodium nitrophenolate is sprayed to tree crowns of macadamia nuts, sodium alginate embedded borax sustained release microsphere suspension liquid is sprayed to leaf surfaces, and a hydrogel complexing agent containing sustained release monopotassium phosphate and amino acid is sprayed to the leaf surfaces; in the full-bloom stage, a composite slow-release emulsion containing liposome-embedded compound sodium nitrophenolate and brassinolide is sprayed to tree crowns of the macadamia nuts, slow-release gel microsphere suspension liquid of borax and amino acid is sprayed to leaf surfaces, and slow-release nano-emulsion containing beta-cyclodextrin-embedded bee wax volatile substances is sprayed to the tree crowns; in the initial fruit setting stage, sulfur-coated slow-release compound fertilizer is applied to the roots of macadamia nut trees, and ionic cross-linked calcium alginate microsphere embedded amino acid slow-release foliar fertilizer is sprayed to the leaf surfaces of the macadamia nut trees.

The invention relates to a silica hydrogel composite, which is shear thinning. The silica hydrogel composite comprises a) up to 85 weight-% of silica particles having a maximum diameter of ≤1000 µm, and b) a silica sol having a silica content of ≤5 weight-%. According to the invention the silica particles comprise an encapsulated agent selected from a GLP-1 receptor agonist, a dual GIP / GLP-1 receptor agonist, or a triple GIP / GLP-1 / GCG receptor agonist.

The invention discloses a sprayable hydrogel composite coating and a preparation method thereof in the field of functional polymer coating materials. The preparation method of the coating comprises the following steps: synthesizing two key compounds: one is a double-dynamic silane cross-linking agent containing catechol and boric acid ester; the adhesive is prepared by esterifying and deprotecting a phenylboronic acid ester derivative and then reacting with a silane coupling agent, and simultaneously provides strong adhesion and dynamic cross-linking capability; and the sulfobetaine-Schiff base bifunctional antibacterial monomer is prepared from a betaine monomer and natural aldehyde through dehydration condensation, and has anti-fouling and antibacterial functions. When the coating is prepared, the acrylamide, the acrylic acid, the antibacterial monomer, the hydrophobic nanoparticles and the photoinitiator are dispersed in a solvent, then the cross-linking agent is added and mixed, a precursor solution is obtained, and the coating is obtained after spraying and ultraviolet curing. The coating prepared by the method shows excellent adhesion, good toughness and long-acting antibacterial and antifouling properties, and is suitable for multiple fields of biomedicine, marine antifouling and the like.

The invention belongs to the technical field of flexible piezoelectric sensors, and relates to a carbon felt-hydrogel composite piezoelectric sensor and a preparation method thereof. The sensor comprises a piezoelectric sensing layer, a cross-scale dual-network hydrogel layer, an electrode layer, a leading-out wire and a packaging layer, the two cross-scale dual-network hydrogel layers are arranged on the upper side and the lower side of the piezoelectric sensing layer in a stacked mode to form a sandwich structure. The cross-scale dual-network hydrogel layer is an elastic hydrogel material formed by compounding a carbon fiber felt skeleton and a molecular-level network polymer, and the molecular-level network polymer penetrates through the interior and the surface of the carbon fiber felt skeleton and is formed by cross-linking and curing; the number of the electrode layers is two, and the two electrode layers are arranged on the outer sides of the two cross-scale dual-network hydrogel layers in a stacked mode respectively. The lead-out wire is electrically connected with the electrode layer; the packaging layer wraps the outer side of the electrode layer. According to the sensor, the mechanical property, the conductivity and the stability of the flexible piezoelectric sensor can be improved.