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1510 results about "Composite hydrogels" patented technology

Compositions And Methods For Inhibiting Adhesions

The present invention provides compositions and methods for inhibiting adhesions. The methods involve administering solutions containing hydrogel precursors such as polysaccharide derivatives, e.g., derivatives of hyaluronic acid, cellulose, or dextran, to a subject at a site where adhesions may form, e.g., as a consequence of surgery, injury, or infection. The hydrogel precursors, e.g., polysaccharide derivatives, become crosslinked following their administration to form a hydrogel that maintains tissue separation. In certain embodiments of the invention one or both solutions contains particles, e.g., polymeric nanoparticles or microparticles, so that a composite hydrogel containing the particles is formed. The solution(s), particle(s), or both, may contain a biologically active agent such as an agent that contributes to inhibiting adhesions. The biologically active agent may be covalently attached to a hydrogel precursor.
Owner:EI DU PONT DE NEMOURS & CO +2

Multiple network compound aquogel material with high mechanical intensity and electrochemical activity and preparation method thereof

The invention relates to a multiple network compound aquogel material with high mechanical intensity and electrochemical activity and a preparation method thereof; artificially-synthesized aquogel material and natural aquogel material are used as a first network or a second network, electric-conducting macromolecule aquogel material is used as a second and a third network, so as to prepare the compound aquogel material with a multiple network structure. The networks at different levels are provided with different mechanical performances which are mutually acted on, so as to lead the compound aquogel material to have high mechanical intensity; the electric-conducting macromolecule aquogel material is used as a constituent of the compound aquogel, so as to lead the compound aquogel material to have electrochemical activity. The multiple network compound aquogel material with high mechanical intensity and electrochemical activity can be applied to the field of electrochemical sensors, supercapacitors, electrochemical exciters, artificial muscles and the like. The invention also discloses a preparation method thereof.
Owner:NANJING UNIV

Nanometer cellulose/polyvinyl alcohol gel composite material

The invention relates to a nanometer cellulose / polyvinyl alcohol gel composite material, which is characterized by comprising hydrogel and aerogel. A preparation method of the nanometer cellulose / polyvinyl alcohol gel composite material comprises the following process steps of 1, nanometer cellulose preparation by a chemical combination mechanical treatment method; 2, composite hydrogel preparation; and 3, composite aerogel preparation. The nanometer cellulose / polyvinyl alcohol gel composite material has the advantages that the composite aerogel belongs to a porous amorphous solid material consisting of nanometer level colloid particles or high-polymer molecules, and a unique open nanometer level porous structure and a continuous three-dimensional reticular structure are adopted, so the density is extremely low, the specific surface area is high, and the porosity is high, wherein the solid phase of the aerogel accounts for 0.2 percent to 20 percent of the total volume percentage, the characteristics of high adsorption catalytic capability, low thermal conductivity, low sound resistance, low refractive index and the like are shown, and wide application prospects are realized in the fields of aviation, spaceflight, chemical industry, metallurgy, energy-saving building and the like.
Owner:SHANDONG LVSEN WOOD PLASTIC COMPOSITE

Sodium alginate-acrylamide composite aquagel, and preparation method and application thereof

ActiveCN105504166AReduce or even avoid stress defectsAvoid stress defectsWater/sewage treatment by sorptionBiocompatibility TestingSewage treatment
The invention discloses a sodium alginate-acrylamide composite aquagel. The preparation method comprises the following steps: 1) proportionally dissolving sodium alginate and acrylamide in water, and uniformly mixing; 2) sequentially adding a crosslinking agent and an initiator, carrying out vacuum degassing treatment, and adding a catalyst; and 3) transferring the obtained mixed solution into a glass mold, and heating to react, thereby obtaining the sodium alginate-acrylamide composite aquagel. The sodium alginate-acrylamide composite aquagel has favorable multivalent ion adsorption capacity and biocompatibility. By combining the polyacrylamide network with the graft copolymerization action of the sodium alginate and acrylamide, the mechanical properties of the aquagel are effectively enhanced. The aquagel is sensitive under the condition of different pH values, can generate intermolecular interactions with multiple cationic dyes and heavy metal ions, and is applicable to the fields of chemical substance adsorptive separation, sewage treatment and the like.
Owner:WUHAN UNIV OF TECH

Process for preparing biocompatible directional carbon nanotube array reinforced composite hydrogel

The invention provides a process for preparing biocompatible directional carbon nanotube array reinforced composite hydrogel, which utilizes the chemical vapor deposition (CVD) technique, the radial cross linking technique and a freezing and thawing method. By permeating polymer sol into a carbon nanotube prefabricated body, aggregating and tangling problems during a compounding process of the carbon nanotube and polymer are resolved, boundary strength of a reinforcing phase and a basis phase is increased, and excellent performances of the nanotube on mechanics and electricity are played sufficiently. The composite hydrogel prepared by utilizing a physical cross linking process does not contain chemical additives and meets requirements on biocompatibility. The composite hydrogel prepared by the process has controllable length and direction of the reinforcing phase of a nanotube array, has integrated mechanics and electricity performances superior to those of the conventional hydrogel,and is adoptive to be applied to the biomedical field such as artificial articular cartilages, tissues engineering supports, nerve cell carries, biomimetic implanted electrode and the like.
Owner:UNIV OF SCI & TECH BEIJING

High-performance graphene/cellulose composite hydrogel and aerogel and preparation methods thereof

The invention belongs to the field of the material science and in particular relates to a high-performance graphene / cellulose composite hydrogel and aerogel and preparation methods thereof. The preparation method of the high-performance graphene / cellulose composite hydrogel comprises the following steps: (1) adding graphite oxide to ionic liquid and ultrasonically dispersing to obtain an ionic liquid solution of the graphite oxide; preparing an ionic liquid solution of cellulose having the mass fraction of 4-6wt%; (2) adding a reducing agent to the ionic liquid solution of graphite oxide, and reducing at 80-100 DEG C for 2-24 hours, thereby obtaining an ionic liquid mixed solution of reduced graphite oxide; (3) mixing the ionic liquid mixed solution of reduced graphite oxide with the ionic liquid solution of cellulose; (4) defoaming the obtained final mixed solution, regenerating by use of a coagulating bath, and washing, thus obtaining the graphene / cellulose composite hydrogel. The composite gel prepared by the preparation method has excellent properties, particularly has excellent the mechanical properties, and can be widely applied.
Owner:SOUTH CHINA UNIV OF TECH

Preparation method of graphene based nano composite hydrogel

The invention relates to a preparation method of a graphene based nano composite hydrogel, and belongs to the field of nano composite hydrogel preparation. An insitu polymerization method is adopted in the invention, which comprises the steps of: (1) preparing graphite into high water-soluble graphite oxide through an improved Hummers method and obtaining graphene emulsions of different varietiesand with different concentrations after peeling and processing; (2) uniformly mixing 1-10g of the graphene emulsions from step (1), 5-10g of water, 0.1-10g of water-soluble monomer, 0.005-0.5g of water-soluble initiator and 1-50[mu]l of catalyst, feeding in nitrogen for 1h to obtain a graphene pre-polymerized solution, and polymerizing under a certain temperature to obtain the graphene based nanocomposite hydrogel. The method of the present invention has a simple technology and is easy for operation; and the obtained nano composite hydrogel has excellent mechanical properties, restorability and environmental responsiveness. Therefore, the graphene based nano composite hydrogel has wide application prospects in biomedicine and machinery industry, etc.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

Preparation method of graphene oxide/poly(N-isopropylacrylamide) composite hydrogel

The invention discloses a preparation method of graphene oxide / poly(N-isopropylacrylamide) composite hydrogel. The preparation method comprises the steps of: firstly, placing the graphene oxide in water and ultrasonically dispersing the graphene oxide for 30-60 min to obtain a graphene oxide colloidal solution; then adding N-isopropylacrylamide, a cross-linking agent and an initiator 1 in the graphene oxide colloidal solution; stirring for dissolving so as to obtain a mixed solution; then inflating nitrogen in the mixed solution to deoxidize fully, then adding an initiator 2 in the deoxidized mixed solution, mixing uniformly and placing the mixture in a thermostatic water bath at 25+ / -1 DEG C so as to obtain the graphene oxide / poly(N-isopropylacrylamide) composite hydrogel. The graphene oxide / poly(N-isopropylacrylamide) composite hydrogel prepared by the method disclosed by the invention has the advantages of good temperature responsiveness and mechanical property and wide application prospect in the biomedical field (such as tissue engineering and drug controlled release).
Owner:QINGDAO UNIV

Method for compounding aquo-gel to porous tissue engineering rack

The present invention discloses the method of compounding aquogel into porous tissue engineering rack. Under sol state, aquogel is first led into porous rack, and the outer condition is altered to convert the sol into gel to obtain porous rack with compounded aquosol. According to requirement, the water sol may have cell growth factor for cell growth and differentiation may be added. The rack the present invention produces possesses the excellent mechanical performance of porous rack and the excellent biocompatibility of aquosol rack simultaneously. The present invention has wide application range, and is suitable for various porous rack with different structures and aquosols and various kinds of cell. The rack may be used widely in tissue engineering field.
Owner:ZHEJIANG UNIV

Carbon aerogel/metal oxide composite material and preparation method and application thereof

The invention discloses carbon aerogel / metal oxide composite material and a preparation method and an application thereof. A cross-linking agent and soluble metal salt are added in a high-molecular aqueous solution so that the inorganic nanoparticles are enabled to be precipitated and dispersed in the organic hydrogel in an in-situ way and the organic and inorganic composite hydrogel can be obtained, a unidirectional porous structure is formed by the hydrogel through multistage freezing and drying and then carbonized and thus the nitrogen-containing multistage porous carbon aerogel / metal oxide composite material is obtained; or the hydrogel is put in the atmosphere of ammonia to be mineralized and then dried under the normal temperature and finally carbonized under the nitrogen protection so that the nitrogen-containing multistage porous carbon aerogel / metal oxide composite material is obtained. The two originally relatively independent stages of carbon aerogel material predation and subsequent metal oxide generation are effectively combined so that the uniform composite characteristic of the inorganic and organic nanoscale in the in-situ precipitation method can be taken, the multistage freezing and drying pore forming function is also developed and the preparation steps can be greatly simplified.
Owner:WUHAN UNIV

Cellulose/two-dimensional layered material composite hydrogel and preparation method thereof

The invention provides a cellulose / two-dimensional layered material composite hydrogel. The composite hydrogel comprises a cellulose three-dimensional network structure and a two-dimensional materialsupported in the cellulose three-dimensional network structure, wherein the two-dimensional layered material is a two-dimensional transition metal carbide, nitride, or carbonitride. According to the composite hydrogel provided by the invention, the two-dimensional layered material can be stably supported in the composite hydrogel system and is not easy to agglomerate; and the composite hydrogel has good compatibility with a biological fluid, and the advantages of full biodegradability and high biological safety, and can be used in the field of biomedicines. The invention also provides a preparation method of the composite hydrogel.
Owner:SHENZHEN UNIV

Poly(3,4-ethylenedioxythiophene)/sulfonated graphene composite hydrogel and preparation method thereof

InactiveCN102558772APorous Structure RegulationEasy to controlElectrolytic capacitorsCapacitanceIron salts
The invention relates to a method for preparing poly(3,4-ethylenedioxythiophene) / sulfonated graphene composite hydrogel with a porous structure through supramolecular self-assembly. The method comprises the following steps of: dissolving sodium polystyrene sulfonate and sulfonated graphene in water, stirring, performing ultrasonic dispersion to ensure that the sodium polystyrene sulfonate and thesulfonated graphene are dissolved, adding a 3,4-ethylenedioxythiophene monomer, uniformly stirring, adding polyvalent iron salt, standing at room temperature and reacting to obtain blocky poly(3,4-ethylenedioxythiophene) / sulfonated graphene composite hydrogel. The poly(3,4-ethylenedioxythiophene) / sulfonated graphene composite hydrogel with a controllable and porous structure is prepared by using the interaction and electrostatic action of a hydrogen bond and a pi-pi bond among the sulfonated graphene, the sodium polystyrene sulfonate and 3,4-ethylenedioxythiophene through supramolecular self-assembly. The prepared composite hydrogel has high electrical conductivity and mechanical strength, and high specific capacitance and cycle stability in electroactive electrolyte.
Owner:HOHAI UNIV

Bioactive nano composite PVA-hydroxyapatite aquagel and its prepn.

The invention refers to a kind of nano complex water gel of bioactive polyvinyl alcohol / the oxhydryl apatite and preparation method which is as follows: prepare the PVA solution by using the purified polyvinyl alcohol; add the grinded and sifted Ca(OH)2 to the pure anhydrous alcohol, then heat the mixture and ultrasonically disperse it to get the alcohol-calcium suspended liquid (or add the metal calcium to the anhydrous alcohol, stir them and make them react to get the calcium alcohol solution); mix said two solutions; then add anhydrous alcohol containing H3PO4 to the mixed solution, and by freezing-melt molding, get the naneo complex water gel of bioactive polyvinyl alcohol. The invention utilizes the hydrophilicity of water-soluble polymer and the static acting force of oxhydryl to make the surface of the generative HA wetting and evenly dispersing.
Owner:SOUTH CHINA UNIV OF TECH

Nanometer bacterial cellulose\polyvinyl alcohol\polyethylene glycol porous composite hydrogel

The invention discloses a nanometer bacterial cellulose\polyvinyl alcohol\polyethylene glycol porous composite hydrogel. The porous composite hydrogel comprises nanometer bacterial cellulose, polyvinyl alcohol and polyethylene glycol. The invention also discloses a preparation method of the porous composite hydrogel. The method comprises the following steps: hydrolyzing clean bacterial cellulose by sulfuric acid to obtain a nanometer cellulose solution, carrying out neutral treatment, mixing the treated solution in a polyvinyl alcohol solution, carrying out ultrasonic dispersion until uniformity, adding a small amount of a polyethylene glycol solution, carrying out ultrasonic stirring mixing, adding the above obtained mixed solution into a glass bead template in a dropwise manner, repeatedly freeze-thawing to cross-link the obtained mixture, and drying to obtain the porous composite hydrogel. The porous composite hydrogel prepared in the invention has the advantages of low cost, mild reaction, fast speed, good biocompatibility, high mechanical strength, uniform porous structure, and wide application prospect in the fields of biomedical science and tissue engineering.
Owner:NANJING UNIV OF SCI & TECH

Artificial articular cartilage material and preparation method thereof

The invention discloses an artificial articular cartilage material, which relates to the field of chemical modification of hydrogel soft materials. Polyacrylamide-sodium alginate hydrogel is modified with graphene oxide and hydroxyapatite, and PAM-ALG-GO-HA composite hydrogel is prepared by a free radical polymerization reaction. The preparation method comprises the following steps: gradually adding needle-like nano HA particles into a GO solution which is uniformly dispersed in advance to form a mixed aqueous solution, adding an acrylamide monomer, an ALG monomer and related reactants for synthesizing PAM-ALG hydrogel, and performing the free radical polymerization reaction to prepare the PAM-ALG-GO-HA composite hydrogel. According to the artificial articular cartilage material disclosed by the invention, chemical modification is performed on the PAM-ALG hydrogel by fully using the two-dimensional structure of a GO nano chip and the functional groups on the surface and the excellent biological activity of HA, the mechanical property and biological activity of the PAM-ALG hydrogel are effectively improved, the application range of the PAM-ALG hydrogel is expanded, and the artificial articular cartilage material has clear scientific significance and a huge application value.
Owner:TIANJIN UNIV

Oxidized sodium alginate/gelatin degradable hydrogel and preparation method thereof

The invention relates to oxidized sodium alginate / gelatin degradable hydrogel and a preparation method thereof. The hydrogel is a composite hydrogel material prepared by blending human body-absorbable fibers, oxidized sodium alginate and gelatin, wherein, the oxidized sodium alginate and gelatin are used as a matrix, and the human body-absorbable fibers are dispersed in the matrix. The preparation method comprises the following steps: (1) carrying out oxidation treatment on the sodium alginate with an oxidizing agent so as to obtain oxidized sodium alginate and preparing an oxidized sodium alginate solution; (2) blending and defoaming the human body-absorbable fibers, a gelatin solution and the oxidized sodium alginate solution, standing an obtained mixture, cross-linking the mixture witha CaCl2 solution so as to obtain the hydrogel, and carrying out cutting processing, disinfection and packaging. The degradable hydrogel provided in the invention has good compatibility with human bodies, a high degradation rate and the effects of stopping bleeding and accelerating healing of wounds; the preparation method for the hydrogel provided in the invention has the advantages of short flow, simple operation, low cost, environmental friendliness and a high economic benefit.
Owner:DONGHUA UNIV

Antibacterial hydrogel composite material and preparation method thereof

The invention provides an antibacterial hydrogel composite material and a preparation method thereof. The antibacterial trauma repair material is hydrogel formed by chitosan and gamma-polyglutamic acid according to a mass ratio of 1 / 0.5-2 through electrostatic interaction, and nano silver is synthesized and loaded in situ on the hydrogel by taking PVP as a dispersant. the preparation method is simple, convenient and quick, and the trauma repair material is high in practicability. The composite hydrogel trauma repair material integrates bactericidal and immune activity, high biocompatibility and hemostatic activity that chitosan has, high water absorbency that gamma-polyglutamic and broad-spectrum antibacterial property and freeness of drug resistance that nano silver has, and composite hydrogel nano silver is small in grain diameter, uniform in distribution and less prone to aggregation, thereby having high antibacterial performance; when the material is used for wound dressing, wound infection can be avoided effectively, and wound healing can be accelerated.
Owner:NANKAI UNIV

High-strength and temperature-sensitive polymer-graphene oxide composite hydrogel and conductive graphene composite hydrogel as well as preparation methods thereof

The invention discloses a high-strength and temperature-sensitive polymer-graphene oxide composite hydrogel and a conductive polymer-graphene composite hydrogel as well as preparation methods thereof. The preparation methods comprise the following steps: dispersing laponite in an aqueous graphene oxide dispersion, stirring, and performing ultrasonic treatment to obtain an uniform dispersion; adding N-isopropyl acrylamide monomer, stirring uniformly and deoxidizing, adding an initiator and a catalyst, transferring the reaction liquid into a glass test tube or a reaction mold for sealing, and performing in-situ free radical polymerization at 15-25 DEG C so as to obtain the polymer-graphene oxide composite hydrogel; and then, reducing the prepared polymer-graphene oxide composite hydrogel with L-ascorbic acid so as to obtain the conductive graphene composite hydrogel. According to the invention, the prepared polymer-graphene oxide composite hydrogel has good mechanical property and thermo-sensitivity; and the prepared conductive graphene composite hydrogel also has good mechanical property, thermo-sensitivity and high conductivity simultaneously.
Owner:SOUTH CHINA UNIV OF TECH

Flexible super capacitor and preparation method thereof

Provided is a flexible super capacitor. Two current collectors are covered on the upper and lower surfaces of a composite hydrogel film; and packaging layers wraps the current collectors and the composite hydrogel film. The composite hydrogel film is integrated by two electrodes and middle electrolyte; and the upper and lower surfaces of the composite hydrogel film are conductive polymer layers serving as the electrodes respectively, and the middle layer thereof is a hydrogel layer serving as the electrolyte. The two current collector layers are covered on the two sides of the electrode-electrolyte composite film respectively, and the formed whole body is packaged in the packaging layers. The preparation method of the flexible super capacitor is characterized by, to begin with, preparing the polyvinyl alcohol hydrogel film; then, preparing the conductive polymer-polyvinyl alcohol composite hydrogel film having a sandwich structure; preparing the current collectors on the upper and lower surfaces of the conductive polymer-polyvinyl alcohol composite hydrogel film; and finally, carrying out packaging.
Owner:INST OF ELECTRICAL ENG CHINESE ACAD OF SCI

Method for preparing three-dimensional graphene-copper nanowire composite aerogel

The invention discloses a method for preparing three-dimensional graphene-copper nanowire composite aerogel. The method comprises the following steps: first, preparing copper nanowires; mixing the copper nanowires and an oxidized graphene solution into an ethylene glycol solution; adding ascorbic acid which serves as a reducing agent; carrying out hydrothermal reaction to obtain three-dimensional graphene-copper nanowire composite hydrogel; finally, washing the three-dimensional graphene-copper nanowire composite hydrogel with a hydrazine hydrate solution which is 0.5 wt%; carrying out freeze-dry treatment to obtain the three-dimensional graphene-copper nanowire composite aerogel. The three-dimensional graphene-copper nanowire composite aerogel adopts a three-dimensional porous structure, and has the advantages of being high in compression performance, low in density, high in electric conductivity and the like.
Owner:ZHEJIANG SCI-TECH UNIV

Biocompatible and temperature-sensitive nano composite hydrogel and preparation method thereof

The invention relates to a biocompatible and temperature-sensitive nano composite hydrogel and a preparation method thereof. The hydrogel contains alkyl acrylamide M1 with temperature-sensitive property, inorganic nano-powder M2 and polyhydroxyalkanoate M3 with good biocompatibility, and the mass percentage of the three is 94-60: 1-20: 5-39. The preparation method comprises the steps that: the M1, the M2 and the M3 are subjected to in-situ free radical polymerization reaction in aqueous solution, and the nano composite hydrogel with biocompatibility and temperature-sensitive property is obtained after soaking and impurity removal. The method has simple and easily controlled preparation process, and can implement automatic desorption of cells by reducing the temperature; the biocompatibility and the temperature-sensitive property of the hydrogel can be adjusted by changing the density of a crosslinker, the dosage of the M3 and the component; and the method can be widely applied in the fields of tissue engineering and the like.
Owner:TIANJIN POLYTECHNIC UNIV

High-performance graphene/cellulose self-assembling composite hydrogel and aerogel and preparation method thereof

The invention belongs to the field of material science, and discloses a high-performance graphene / cellulose self-assembling composite hydrogel and aerogel and a preparation method thereof. The preparation method comprises the following steps: (1) firstly soaking cellulose raw materials, then carrying out defibering to prepare paper pulp dispersion liquid; (2) adding graphite oxide to the prepared paper pulp dispersion liquid, and carrying out ultrasonic dispersion to obtain a graphite oxide / cellulose mixed solution; and (3) adding a reducing agent into the graphite oxide / cellulose mixed solution, reducing for 3-24 h at the temperature of 40-100 DEG C, or adopting a hydrothermal reduction method, and washing the obtained product to obtain a graphene / cellulose self-assembling composite hydrogel; and then drying the composite hydrogel to obtain a composite aerogel. Through the simple method, the prepared composite gel is excellent in performance such as electrical conductivity and thermal stability particularly, and is wide in application.
Owner:SOUTH CHINA UNIV OF TECH

Hydroxybutyl chitosan/oxidized sodium alginate/nano-silver composite hydrogel dressing plaster

The invention belongs to the technical field of medical material production and particularly discloses a hydroxybutyl chitosan / oxidized sodium alginate / nano-silver composite hydrogel dressing plaster. The steps of manufacturing the hydroxybutyl chitosan / oxidized sodium alginate / nano-silver composite hydrogel dressing plaster are that a medical non-woven fabric is soaked in oxidized sodium alginate (OSA) aqueous solution (a crosslinking agent) and then taken out; nano-silver (n-Ag) colloidal solution is added dropwise to hydroxybutyl chitosan (HBCS) aqueous solution and mixed, the well treated non-woven fabric is evenly coated with the mixed solution, hydrogel is formed by crosslinking at normal temperature and then transferred to a PU film medical adhesive tape with pressure-sensitive adhesive, the hydrogel is covered with release paper, the HBCS / OSA / n-Ag composite hydrogel dressing plaster is obtained, and gamma ray sterilization is performed after sealing. According to the technical scheme, the hydroxybutyl chitosan / oxidized sodium alginate / nano-silver composite hydrogel dressing plaster has the advantages of being low in cost and simple in process; in view of the facts that HBCS has good biocompatibility, OSA is non-toxic to the human body and n-Ag has good antimicrobial performance, the prepared hydrogel can be applied to wound dressings and hemostatic materials and the like. The hydroxybutyl chitosan / oxidized sodium alginate / nano-silver composite hydrogel dressing plaster has the advantages of having hygroscopicity and being remarkable in antibacterial performance and low in cytotoxicity.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Hyaluronic acid-sodium alginate composite hydrogel and preparation method thereof

InactiveCN102070786AHigh hardnessHigh viscoelasticityCross-linkAnti-hyaluronidase
The invention discloses hyaluronic acid-sodium alginate composite hydrogel and a preparation method thereof. The composite hydrogel is prepared from the following steps of: (1) dissolving hyaluronic acid and sodium alginate into water to obtain a solution 1; (2) adding a cross-linking agent to the solution 1, and regulating the pH value to be 4.0-5.5 with a buffer solution to obtain a solution 2; (3) adding a carboxyl activating agent to the solution 2 and stirring; and regulating and controlling the pH value of the solution 2 to be 2.0-5.5 in the stirring process until gel is formed to obtain the hyaluronic acid-sodium alginate composite hydrogenl. The invention provides a new approach for the modification of the hyaluronic acid, and the composite modified compound prepared by using the method has the advantages of higher mechanical property, capacity of resisting enzymatic degradation of the hyaluronic acid, biocompatibility, and the like and has potential application in the aspects of surgical operations and tissue engineering.
Owner:INST OF AGRO FOOD SCI & TECH CHINESE ACADEMY OF AGRI SCI

Natural polysaccharide/nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing and radiation synthesis method thereof

The invention provides a natural polysaccharide / nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing which is composed of a backing layer, a hydrogel dressing layer and a strippable layer. A synthesis method of the natural polysaccharide / nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing comprises performing radiation crosslinking on raw materials, namely 10-40% of natural polysaccharide, 0.1-10% of nano-TiO2, 0.1%-5% of radiation sensitizer, 0.1%-3% of pH regulator, 0.1%-3% of surfactant and 60%-95% of water, by use of an electron beam or gamma ray by a radiation dose of 10-150kGy and at a dose rate of 10-80kGy / pass. The natural polysaccharide / nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing is sheared, bagged and sterilized by radiation, and then stored for a long time. The natural polysaccharide / nano-TiO2 composite light-sensitive antimicrobial hydrogel dressing has the advantages that the maximization and optimization of the properties of the composite hydrogel, light-sensitive and antimicrobial properties are united organically, and the multiple-element composite synergic antimicrobial effect of the nano-TiO2-natural polysaccharide hydrogel is also realized; meanwhile, the composite hydrogel dressing has the characteristics of air permeability, no bonding with tissues, good flexibility and the like, and thus is suitable for protecting and treating various wounds.
Owner:HUBEI UNIV OF SCI & TECH

Composite hydrogel and preparation method thereof

The invention relates to composite hydrogel and a preparation method thereof. The composite hydrogel is hydrogel which takes a three-dimensional fiber network material as a skeleton, that is, the hydrogel comprises a three-dimensional fiber network material, wherein the three-dimensional fiber network material is a network structured material made of tingled fiber. As the three-dimensional fiber network material of the composite hydrogel is directly combined with the hydrogel, the purpose of strengthening the hydrogel can be achieved without changing the structure of the hydrogel self. Compared with a loosened and porous structure inside the hydrogel, the three-dimensional fiber network structure is dense, and medicines and active factors in the hydrogel can be densely coated, so that a slow-release effect can be achieved, the release velocities of the medicines can be reduced, and the utilization rates of the medicines can be increased.
Owner:DONGHUA UNIV

Inorganic thermal-insulation mortar and production method thereof

The invention belongs to the technical field of building materials and particularly relates to inorganic thermal-insulation mortar and a production method thereof. The production method includes: using rice husks as the raw material, performing pickling preprocessing, calcining, using alkali dissolution to extract sodium silicate, removing impurities to obtain silicic acid, adding aluminum silicate fibers and tetraethyl silicate to serve as the framework of gel, performing condensation polymerization to deposit silicon dioxide composite hydrogel on the framework, cleaning with anhydrous ethanol and normal hexane, using trimethylchlorosilane to perform hydrophobic modification to obtain silicon dioxide aerogel, using the capillary force of the silicon dioxide aerogel adsorb paraffin, serving as the phase change thermal storage material, into pores to compact the aerogel, mixing the prepared silicon dioxide composite aerogel phase change material with expanded and vitrified small balls, silica fume and the like, and discharging to obtain the inorganic thermal-insulation mortar. The prepared inorganic mortar is small in heat conductivity coefficient, low in contractibility rate, high in strength, capable of effectively increasing the crack resistance and seepage resistance of the mortar and capable of prolonging building service life.
Owner:常州市天宁区鑫发织造有限公司

Anisotropic nanocomposite hydrogel

Anisotropic nanocomposite hydrogel materials are created using a process in which a hydrogel-forming material is crosslinked in the presence of nanoscale cellulose and subsequently thermally cycled under an applied tensile strain. Such materials are capable of exhibiting high mechanical and viscoelastic anisotropy, increased stiffness when subjected to large strain, and are suitable for a broad range of soft tissue replacement applications. In addition controlled release of bioactive agents properties can be designed into medical devices fabricated from such nanocomposite materials.
Owner:AXCELON BIOPOLYMERS COPRORATION
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