This invention discloses a rapid
mass spectrometry method and kit for the simultaneous detection of multiple components in body fluids, belonging to the field of biological detection and
identification technology. It can rapidly detect trace compounds such as drugs and biomarkers in complex biological samples. This kit mainly utilizes loaded functional materials to achieve extraction and enrichment of target analytes and is equipped with a quick connector for
coupling with a
detector to achieve
rapid detection. Compared with traditional methods, the significant advantages of the method established by this kit are that it does not require complex sample pretreatment, allows for micro-quantitative sampling, requires
small sample volumes, facilitates convenient storage of biological samples, is easy to operate, does not require specialized technical personnel, and enables rapid on-site detection when coupled with portable
mass spectrometry. This kit has been successfully used for the detection of
quinine, procainamide
hydrochloride,
atenolol, and nortriptyline in complex samples such as blood and serum, and has significant clinical and economic value.