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2 results about "Timolol" patented technology

This medication is used to treat high pressure inside the eye due to glaucoma (open angle-type) or other eye diseases (e.g., ocular hypertension).

Pharmaceutical compositions comprising timolol

ActiveUS12599607B2Organic active ingredientsSenses disorderIntra ocular pressureAlkane
The present invention relates to pharmaceutical composition comprising the beta 1 (β1)-receptor blocker timolol and a liquid vehicle comprising a semifluorinated alkane. The pharmaceutical composition of the present invention may be useful for topical administration, for example ophthalmic topical administration and for use in the treatment of glaucoma, increased intraocular pressure, ocular hypertension and / or a symptom associated therewith.
Owner:NOVALIQ GMBH

Formulations for delivery of a colloidal prodrug to lower intraocular pressure (IOP) for a prolonged time

The present disclosure relates to colloidal drug aggregates (CDAs) that are further embedded in hydrogels for sustained local delivery. Preferred drugs include beta-blocker prodrugs and ROCK inhibitors for use in treating glaucoma. In particularly preferred embodiments, the CDAs comprise prodrugs of timolol or netarsudil in combination with phospholipid stabilizers. Preferred hydrogels include hyaluronan crosslinked using an oxime bond.
Owner:DANG MICKAEL +1