636 results about "Microcrystalline cellulose" patented technology

A coating composition for a substrate, which includes: a microcrystalline cellulose composition, at least one silane, at least one acid catalyst, a liquid dispersion phase, and optionally at least one inorganic filler. Also, the use of this composition for the release coating of a substrate such as a paper surface or a metal surface. Finally, an article having at least one surface is coated with the coating composition.

The invention relates to the technical field of pharmaceutical preparations, in particular to a preparation process of carbon dots for killing helicobacter pylori and application of the carbon dots in oral pharmaceutical preparations. The preparation method comprises the following steps: mixing microcrystalline cellulose and glycerol, freezing and crushing at an ultralow temperature, and selectively hydrolyzing by combining citric acid-malic acid mixed acid liquor to efficiently prepare a high-crystallinity cellulose nanocrystal template; the controllable synthesis of the carbon dots is realized by utilizing the hydrogen-bond interaction of hydroxyl / carboxyl on the surface of the cellulose nanocrystal and the nitrogen doping effect in the polymerization and carbonization process of citric acid and urea. Besides, when a sodium alginate-chitosan double-layer structure is constructed, carbon dots are introduced into the inner layer to endow the inner layer with special performance, a protein-polysaccharide network is formed on the outer layer through transglutaminase enzymatic crosslinking, and the oxidation resistance and mechanical strength are enhanced through secondary curing of tea polyphenol. According to the invention, food-grade raw materials are used for realizing high-efficiency antibiosis, the oral preparation safety specification is met, and the clinical transformation potential is realized.

The invention relates to the field of aquatic feed, and provides a low-temperature adhesive type aquatic feed particle composition and a preparation method thereof. The composition is composed of puffed soybean meal, flour, fish meal, low-temperature directed enzyme, microcrystalline cellulose, modified zein nanoparticles, a protein adhesive and a modified zein ethanol water solution. The preparation method comprises the following specific steps: reacting soybean protein isolate with cross-linking enzyme to generate a protein adhesive, reacting proanthocyanidins with gallic acid to generate gallic acylated proanthocyanidins, and carrying out multi-step treatment on zein. Experimental results show that the composition has excellent water resistance and oxidation resistance, and the growth efficiency and the survival rate of aquatic animals are remarkably improved. The preparation method is simple, the cost is low, heat-sensitive substances in the feed are not damaged, and an economical, efficient and nutrient-rich feed solution is provided for aquaculture.

The invention discloses a degradable nanocellulose sustained-release drug-loaded film and a preparation method thereof, and belongs to the technical field of drug functional materials. The preparation method comprises the following steps: mixing and stirring microcrystalline cellulose and 64wt% sulfuric acid solution, centrifuging, dialyzing to be neutral, and freeze-drying to obtain CNCs; cNCs, NaIO4 and water are mixed and then subjected to a light-shielding reaction, ethanol precipitation is added, dialysis purification is conducted, freeze drying is conducted, and formylation modified CNCs are obtained; mixing and stirring the aldehyde modified CNCs, sericin, polyvinyl alcohol, water and a target drug to obtain a core layer solution; dissolving a polylactic acid-glycolic acid copolymer into a mixed solution of chloroform and DMF (Dimethyl Formamide) to obtain a shell solution; the core layer solution and the shell layer solution are subjected to coaxial electrostatic spinning forming to obtain the drug-loaded fiber, then the drug-loaded fiber is subjected to biomimetic mineralization surface modification to obtain the degradable nanocellulose sustained-release drug-loaded film, the drug loading rate is increased, the mechanical property of the drug-loaded film is improved, and the sustained-release and release-controllable effects are achieved.

The invention discloses a composition containing a honeysuckle extract, a tablet and a production method thereof, and belongs to the technical field of medicines.The preparation method comprises the steps that pseudo-ginseng, honeysuckle and radix isatidis are dried and ground into powder, a hydrogel film coating with an environmental response function is prepared, and the hydrogel film coating has porosity and environmental tolerance, can improve the slow release performance of a medicine, and has a good application prospect. The active ingredient preservation time of the medicine is protected, and the medicine effect is prolonged; according to the hydrogel film coating, natural plant-derived polysaccharide and microcrystalline cellulose with excellent biocompatibility are used as raw materials, the raw materials are subjected to swelling treatment and then grafted with a polyethylene glycol-maleic anhydride copolymer, then an iron metal framework sensitive to the pH value is subjected to hydrothermal synthesis on the surface, the iron metal framework serves as a crosslinking center, a hydrogel film structure is generated through crosslinking to serve as the coating, and the hydrogel film coating is prepared. Therefore, the permeation resistance and mechanical strength of the coating are balanced, the swelling rate difference is avoided, the structural stability of the coating is guaranteed, and the tablet prepared from the coating can be used for treating cold and has a good drug effect.

The invention discloses a plasmin lumbrukinase peptide dietary therapy formula suitable for rehabilitation of cardiovascular and cerebrovascular diseases, blood circulation promoting, blood stasis removing, thrombolysis, collateral dredging and microcirculation improving, and relates to the technical field of medicine and food homology dietary therapy. Soybean protein isolate and earthworm protein are used as core thrombolytic active raw materials, isomaltooligosacharide, xylitol, German Jilida collagen peptide, soybean peptide powder, Belgian imported inulin, red yeast rice and natto powder are compounded, microcrystalline cellulose and magnesium stearate are used as auxiliary materials, and probiotics / metabiotics strains such as rhamnolactobacilli JYLR-005 and the like can be selectively added. The raw materials have a synergistic effect through precise matching, plasmin and lumbrukinase peptide in earthworm protein can directly dissolve thrombus fibrin, natto powder and red yeast rice assist in lowering lipid and dissolving thrombus, multiple active peptides and prebiotics regulate intestinal microecology to improve microcirculation of the whole body, probiotics / metabiotics further strengthen the metabolic capacity of the body, no chemical medicine is added in the whole process, and the traditional Chinese medicine composition is free of toxic and side effects and free of toxic and side effects. The safety is high; the dietary therapy composition can achieve postoperative rehabilitation conditioning of cardiovascular and cerebrovascular diseases through daily consumption, effectively promote blood circulation to remove blood stasis, dissolve thrombus and dredge collaterals, improve microcirculation and relieve various discomfort caused by blood vessel clogging, raw materials are easy to obtain, compatibility is scientific, and the dietary therapy composition is suitable for large-scale production and popularization.

The invention discloses a composite plant polypeptide composition with the effects of repairing pancreas and reducing blood sugar. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 50 parts of ginsenoside, 5 to 30 parts of radix astragali seu hedysari extract, 3 to 20 parts of radix rehmanniae polysaccharide, 2 to 15 parts of radix trichosanthis alkaloid, 5 to 25 parts of rhizoma dioscoreae polysaccharide, 5 to 30 parts of bitter gourd polypeptide, 3 to 20 parts of folium mori alkaloid, 8 to 40 parts of rhizoma polygonati polysaccharide, 5 to 25 parts of fructus hippophae flavone, 10 to 35 parts of wheat germ peptide, 2 to 15 parts of coptis berberine, 10 to 45 parts of corn stigma polysaccharide and 3 to 20 parts of saussurea involucrata polyphenol. 1-10 parts of sophora flavescens total alkaloids, 5-25 parts of a dendrobium extract, 5-30 parts of a radix puerariae extract, 8-35 parts of L-arabinose and 10-40 parts of small molecule peptides; 20 to 100 parts of collagen peptide and 15 to 80 parts of albumin peptide; 5-50 parts of microcrystalline cellulose, 3-30 parts of fructo-oligosaccharide and 0.5-5 parts of magnesium stearate; the limitation of single sugar control or simple component mixing in the prior art is broken through, a synergistic system of plant active components and functional polypeptides is constructed, and the purity and retention rate of the plant active components are improved by optimizing the extraction process.

The invention belongs to the technical field of energy storage materials, and particularly discloses preparation and application of a high-performance asphalt-based porous carbon material. The method comprises the following steps: pre-treating asphalt; carrying out hydrothermal synthesis on microcrystalline cellulose and phytic acid to obtain cellulose ester; the preparation method comprises the following steps: compounding humic acid, hectorite powder and cellulose ester, and freeze-drying to obtain a compound additive; carrying out microwave-hydrothermal reaction on the pretreated asphalt and a compound additive to form a precursor; and activating the precursor, carbonate and phosphate in a multi-section gradient atmosphere, and finally washing and drying to obtain the porous carbon material. According to the method, strong base etching is replaced by synergistic pore-forming and atmosphere activation of the composite additive, so that green controllable pore expansion and uniform doping of heteroatoms are realized; and a graded pore channel structure is accurately constructed through multi-section carbonization. The obtained material has a three-dimensional interpenetrating network, a high specific surface area and excellent conductivity, can effectively buffer ion embedding stress, remarkably improve electrochemical stability and inhibit volume expansion, and is suitable for lithium and sodium ion battery negative electrodes and supercapacitor electrodes.

The invention discloses traditional Chinese medicine suspension eye drops and a preparation method thereof, and the traditional Chinese medicine suspension eye drops are prepared from the following raw materials in parts by weight: 1-3 parts of a traditional Chinese medicine composition, 4-7 parts of hydroxypropyl-beta-cyclodextrin, 0.5-2 parts of microcrystalline cellulose-sodium carboxymethyl cellulose and auxiliary materials. The traditional Chinese medicine suspension eye drops provided by the invention abandon a traditional eye ointment form, are directly dropped for use, are convenient to use, have good stability and dispersity, and are excellent in use curative effect and medication experience; on the basis of keeping the clinical efficacy of the Marcher eight-treasure ancient prescription, secondary development and research are scientifically carried out, so that the Marcher eight-treasure ancient prescription plays a greater clinical treatment role, and has a wider market development prospect.

The invention relates to the field of veterinary drugs, in particular to a veterinary GS-441524 tablet and a preparation method thereof. In the application, the GS-441524 raw material medicine, the filling agent, the disintegrating agent, the lubricating agent and the stabilizing agent are used as raw materials, the combination of mannitol and microcrystalline cellulose is selected as the filling agent, and coating is performed, so that the novel veterinary GS-441524 tablet is prepared, the medicine loss caused by thermal decomposition of API in the tabletting process is reduced, and the uniformity and the stability of the medicine in the tablet are improved.

The invention relates to the technical field of functional nutritious food, in particular to multi-layer skin nutrition powder with a whole-spectrum skin growth and repair promoting effect and a preparation method and application thereof, the core of the multi-layer skin nutrition powder is composed of a collagen peptide system (60-62%), a proteoglycan system (20-22%) and the like, collagen peptide is compounded with three sources of cattle, fish and chicken, and the multi-layer skin nutrition powder has the advantages that the multi-layer skin nutrition powder is prepared; according to the present invention, with the combination of the following components, the skin structure and activity are jointly promoted by using the synergistic effect of the functional polypeptide compound (2.5-3.5%) and the plant active component (3.5-4.5%) rich in asiaticoside and procyanidine, and the nutrition enhancers (4-5%) such as L-ascorbic acid and amino acid chelated zinc and the food-grade auxiliary materials (8-10%) such as microcrystalline cellulose are integrated in the formula, such that the various systems achieve the synergistic effect so as to achieve the effect of nourishing the skin; through the synergistic compatibility of the three-source collagen peptide, the comprehensive supplement of various types of collagen in skin tissues is realized.

The invention relates to the technical field of polypropylene materials, in particular to wear-resistant modified polypropylene plastic for a turnover box and a preparation method of the wear-resistant modified polypropylene plastic. The wear-resistant modified polypropylene plastic for the turnover box comprises the following raw materials in parts by weight: 70-80 parts of polypropylene, 3-8 parts of polypropylene-g-maleic anhydride, 1-3 parts of a lubricant, 10-15 parts of modified talcum powder, 4-8 parts of titanium dioxide, 5-10 parts of microcrystalline cellulose and 0.5-2.0 parts of an epoxidized ultraviolet light absorber. The polypropylene, the polypropylene-g-maleic anhydride, the lubricant, the modified talcum powder, the titanium dioxide, the microcrystalline cellulose and the epoxidized ultraviolet light absorber are compounded to prepare the wear-resistant modified polypropylene plastic, and the wear-resistant modified polypropylene plastic not only has excellent mechanical properties, but also has excellent aging resistance and antibacterial property, so that the service life of the wear-resistant modified polypropylene plastic is prolonged.

The invention belongs to the field of medicines, and relates to a perindopril amlodipine solid preparation as well as a preparation method and application thereof. In the prior art, when an in-vitro dissolution behavior of an imitated medicine of perindopril and amlodipine tablets is investigated, it is found that the release behaviors of the perindopril and amlodipine tablets are difficult to keep consistent with those of an original developed preparation at the same time, so that the safety and effectiveness of the imitated medicine are not guaranteed. A large number of experiments find that the particle size distribution and the water content of the microcrystalline cellulose are controlled, so that the in-vitro dissolution curve of the perindopril amlodipine solid preparation is similar to that of an imported original development agent produced by an original research company, the possibility of bioequivalence with the original development agent is improved, and the drug consistency evaluation requirement is met.

The invention relates to an anti-aging capsule compounded by PQQ and mitochondrial nutrients, and discloses an anti-aging capsule which is prepared by synergistically compounding a plurality of mitochondrial nutrients according to a scientific proportion and supplementing high-purity raw materials and slow-release dosage forms to realize energy metabolism activation and anti-oxidation synergistic intervention. Therefore, the anti-aging capsule systematically delays aging through multi-target regulation and control of mitochondrial functions. The capsule is characterized by comprising the following components in parts by weight: 1-20 mg of pyrroloquinoline quinone disodium salt (PQQ), 20-100 mg of coenzyme Q10, 50-200 mg of L-carnitine tartrate, 10-100 mg of alpha-lipoic acid, 50-300 mg of nicotinamide mononucleotide (NMN) or nicotinamide nucleoside (NR), and 10-50 [mu] g of selenoprotein or organic selenium yeast, and a capsule carrier comprises 100 mg of gelatin or a plant-derived capsule shell, 180 mg of microcrystalline cellulose, 5 mg of magnesium stearate and 5 mg of silicon dioxide.

The invention relates to the technical field of self-leveling, and particularly discloses high-density gypsum-based self-leveling mortar and a preparation method thereof, the high-density gypsum-based self-leveling mortar comprises building gypsum, modified heavy calcium powder, quartz sand, modified silica powder, Portland cement and a plurality of additives, the modified heavy calcium powder is activated by a silane coupling agent and is subjected to composite coating modification by sodium alginate-microcrystalline cellulose, the modified silica powder is activated by a silane coupling agent and is subjected to coating modification by chitosan, and the preparation method comprises the following steps: S1, preparing the chitosan-coated modified silica powder; s2, preparing sodium alginate-microcrystalline cellulose composite coated modified heavy calcium powder; s3, uniformly mixing all the dry materials, adding the mixed admixture and water, and stirring to prepare mortar; according to the self-leveling mortar disclosed by the invention, pores are filled in a self-adaptive manner through the characteristic that the surface coating layers of the modified heavy calcium powder and the modified silica powder absorb water and swell, a stable high-molecular reinforced framework is formed after drying, and the high-molecular reinforced framework and mortar components generate a synergistic effect, so that the compactness of the self-leveling mortar is effectively improved.

The preparation method of the environment-friendly anti-aging packaging base paper comprises the following steps: taking softwood pulp and dissolving pulp, pulping for the first time, adding microcrystalline cellulose, and stirring to form first pulp; adjusting the pH value of the first slurry to be neutral, adding a water-soluble chitosan-polyphenol compound, and pulping for the second time to form second slurry; adding oxidized sodium alginate into the second pulp, and pulping for the third time to form third pulp; forming raw paper according to a papermaking process; the invention further provides packaging base paper which has the characteristic of good anti-aging performance. Softwood pulp and dissolving pulp are used as papermaking raw materials, microcrystalline cellulose, a water-soluble chitosan-polyphenol compound and oxidized sodium alginate are used, a pulping process which is sequentially added according to a sequence is formed, a stable fiber network is constructed layer by layer, and a mechanism of skeleton supporting, covalent crosslinking and antioxidant end capping is formed. The anti-aging performance of the raw paper is improved.

The invention discloses a mollusk attractant as well as a preparation method and application thereof in snail prevention and control, and belongs to the technical field of biopesticides, temperature-responsive microcrystalline cellulose particles are used as a main component of a coating premix, and an attractant base material containing active components, essence, amino acid, molasses and flour is coated, so that the mollusk attractant is obtained. The attractant has temperature responsiveness and can meet the field temperature of snails in spring and autumn high-incidence periods in agricultural production, the essence and the molasses are main components with an inducing function, snails can be better trapped, and the snails are not prone to loss due to the influence of the complex environment in a farmland; the temperature-responsive microcrystalline cellulose particles disclosed by the invention have amphipathy, the hydrophilicity can realize rapid spreading of the attractant in a farmland, and the hydrophobicity can realize that the attractant is not easily washed by water flow and rainwater in the farmland, so that the service life of the attractant is prolonged.

The invention discloses a full-biodegradable bamboo fiber film material and a preparation method thereof. The full-biodegradable bamboo fiber film material is composed of a bamboo fiber composite matrix, a biodegradable reinforcing system and a multifunctional cross-linking agent. The bamboo fiber composite matrix is a mixture of bamboo pulp fiber pretreated by supercritical CO2 and microcrystalline cellulose; the biodegradation enhancing system is composed of nano calcium carbonate-montmorillonite composite particles and a polylactic acid-glycolic acid copolymer, and the composite particles are modified by a silane coupling agent; the multifunctional cross-linking agent is an esterification product of citric acid and glycerol. The preparation method comprises the steps of bamboo fiber supercritical pretreatment, composite reinforced particle preparation, melt extrusion, two-way stretching, gradient heat setting and the like, and finally the antibacterial surface layer is formed through chitosan surface treatment. The material realizes the balance of biodegradability and mechanical properties through raw material synergy and process optimization, and is suitable for the fields of packaging, agricultural coverage and the like.

The invention provides a sustained-release pellet containing gamma-aminobutyric acid, the sustained-release pellet comprises a pellet core and a coating layer wrapping the pellet core, the pellet core contains a physiologically active substance, and the physiologically active substance is gamma-aminobutyric acid; the pellet core comprises the following components in parts by weight: 15-40 parts of gamma-aminobutyric acid, 30-55 parts of a filling agent, 1-30 parts of a lubricating agent and 0.5-5 parts of an anti-caking agent; the filling agent comprises at least one of microcrystalline cellulose, powdery cellulose, starch and derivatives thereof, hydroxypropyl cellulose, hydroxypropyl methylcellulose, low-substituted hydroxypropyl cellulose, sugar or sugar alcohol and fruit and vegetable powder; the lubricant comprises at least one of talcum powder, magnesium stearate, stearic acid, glycerol and leucine; the anti-caking agent comprises at least one of magnesium carbonate, tricalcium phosphate, calcium hydrophosphate and silicon dioxide.

The invention discloses a domestication method for efficiently degrading tobacco waste to produce hydrogen by using mixed flora, which comprises the following steps: carrying out anaerobic enrichment domestication culture by taking manure compost as a bacterial source and cellulose prepared from tobacco waste as a core component of a domestication culture medium; the domestication culture medium contains cellulose, ammonium bicarbonate and monopotassium phosphate, and the cellulose concentration gradient is gradually increased without adjusting the pH value; stopping culturing when the hydrogen content in the biogas is reduced by 10%, transferring the biogas to a fresh domestication culture medium for passage according to an inoculum size of 10-20%, and continuously domesticating for 20-40 rounds; inoculating the domesticated mixed flora culture solution into a cellulose liquid fermentation culture medium containing microcrystalline cellulose, ammonium bicarbonate, monopotassium phosphate and a nutrient solution according to the inoculum size of 10-20%; the initial pH of the fermentation liquor is adjusted to 6.5-7.5, high-purity nitrogen is introduced to create an anaerobic environment, and hydrogen is produced through fermentation under the conditions of 35 + / -1 DEG C and 120 r / min. According to the method, flora is easy to culture, hydrogen production is efficient and stable, tobacco waste resources can be utilized, flora stability is high, adaptability is high, and strict sterile conditions are not needed.

The invention discloses a preparation method of high-color-fastness woven body paper and the high-color-fastness woven body paper, and relates to the technical field of papermaking, and the preparation method of the high-color-fastness woven body paper comprises the steps of preparing a composite dyeing assistant and preparing the woven body paper. The preparation method comprises the following steps: stirring and mixing cationic microcrystalline cellulose, sodium carboxymethyl cellulose, triethanolamine myriceate, glucan hydroxypropyl trimethyl ammonium chloride, a water-based polycarbodiimide cross-linking agent and deionized water to obtain a composite dyeing assistant, then adding the composite dyeing assistant into slurry, adding a water-based dye, and carrying out a papermaking process to obtain the composite dyeing assistant. According to the method, the color fastness of the woven body paper can be improved. The sun-proof grade of the high-color-fastness woven body paper is greater than or equal to 4 grades.

This invention provides a breathable plaster matrix for application and its preparation method, belonging to the field of polymeric dressings and plasters. The plaster matrix raw materials include terpene-modified rosin beeswax, hydrogenated rosin glyceryl ester, camellia oil, castor oil, stearic acid hydrophobically modified microcrystalline cellulose, zinc oxide, glycerin, coated citric acid, sodium bicarbonate, polyethylene glycol, camphor, and menthol. The terpene-modified rosin beeswax is prepared by reacting rosin and α-pinene in the presence of di-tert-butylperoxyisopropylbenzene, followed by the addition of white beeswax and maleic anhydride, and then the addition of trimethylolpropane. The stearic acid hydrophobically modified microcrystalline cellulose is microcrystalline cellulose coated with stearic acid. The coated citric acid is citric acid coated with hydrogenated castor oil. This invention's plaster matrix significantly improves skin breathability, application comfort, and biocompatibility while ensuring sufficient adhesion, formability, and drug loading capacity.

The invention discloses a pharmaceutical composition for improving liver dysfunction, the pharmaceutical composition comprises a tablet core and a coating film, the tablet core comprises 30-40 parts of mono-ammonium glycyrrhizinate (20-30 parts by weight of glycyrrhizin), 20-30 parts of glycine, 20-30 parts of methionine, 55-65 parts of a filler, 2-10 parts of a disintegrating agent, 1-10 parts of an adhesive and 1-10 parts of a lubricant, and the coating film is a gastric soluble film coating; wherein the filling agent is formed by compounding lactose, microcrystalline cellulose, calcium carbonate, calcium hydrophosphate and mannitol, the mass ratio of the lactose to the microcrystalline cellulose to the calcium carbonate to the calcium hydrophosphate to the mannitol is (1-24): (1-35): (1-25): (1-9): (1-9), and the pharmaceutical composition for improving liver dysfunction has good dissolution and stability.

The application provides a bupropion hydrochloride sustained-release tablet and a preparation method, and belongs to the technical field of pharmacy. The pharmaceutical composition contains 150 parts of bupropion hydrochloride, 122.5-157.5 parts of glycerin monostearate, 17.5-22.5 parts of triethyl citrate, 68-104 parts of microcrystalline cellulose and 2-6 parts of magnesium stearate, wherein the bupropion hydrochloride raw material and the glycerin monostearate and the triethyl citrate are prepared into a solid dispersion through a hot melt extrusion process. The application provides a bupropion hydrochloride sustained-release tablet which is stable in drug release, slow in growth of related substances, does not need to be coated and can be taken and eaten, and a preparation method.

The invention relates to high-stability amoxicillin powder for livestock. 100 kg of the amoxicillin powder mainly comprises the following raw materials by weight: 10 to 30 kg of amoxicillin, 2.5 to 7.5 kg of potassium clavulanate, 0.6 to 0.7 kg of a hydroxypropyl-beta-cyclodextrin-baicalin and chlorogenic acid compound inclusion body, 1.8 to 2.4 kg of citric acid and calcium carbonate controlled release microspheres, 23.7 to 45 kg of oat beta-glucan, 18 to 25 kg of pre-gelatinized cassava starch, 3 to 4 kg of mannitol, 8 to 12.7 kg of silanized microcrystalline cellulose, and the balance of water. The coating comprises the following components by weight: 0.8 to 1.2 kg of nano silicon dioxide, 2.0 to 2.5 kg of hydroxypropyl methylcellulose and 0.6 to 1.0 kg of zinc diricinoleate. The powder is dried at low temperature, so that the degradation rate of beta-lactam rings is reduced, the stability of amoxicillin is improved, and the bioavailability of the medicine is improved.

The invention relates to a preparation method of bio-based dual-network intelligent medical hydrogel, and relates to a preparation method of high polymer material medical hydrogel, the hydrogel takes bio-based material microcrystalline cellulose as a raw material, the bio-based material microcrystalline cellulose and a green cross-linking agent citric acid are esterified and cross-linked to form single-network (SN) hydrogel, and the single-network hydrogel and the green cross-linking agent citric acid are further subjected to solution treatment to form dual-network (DN) hydrogel. Anthocyanin is introduced in the process of forming the double-network hydrogel. In the SN forming process, risks possibly caused by toxic residues of a chemical cross-linking agent are effectively avoided; the anthocyanin is used as a natural antioxidant, so that the hydrogel has the functions of eliminating free radicals, resisting cancer, resisting inflammation, inhibiting bacteria and the like; meanwhile, due to the introduction of anthocyanin, the prepared DN hydrogel has excellent mechanical properties and obvious pH response, and can be applied to the field of wound dressings. The wound healing condition can be judged according to the color change caused by pH fluctuation, the unnecessary dressing replacement frequency is reduced, and the treatment efficiency is improved.

This invention discloses a highly active compound health supplement made from Cordyceps sinensis, Artemisia argyi, and rhubarb, and its preparation method, belonging to the field of health food and pharmaceutical preparation processing technology. The method includes: adding artificial Cordyceps sinensis ultrafine powder, prepared Rhubarb tanguticum fine powder, Artemisia argyi leaf extract, microcrystalline cellulose PH102, and maltodextrin into a mixer and premixing at 25-35 rpm to allow the powder to adhere to the surface of the excipients; after tableting, the tablets are subjected to ultra-high pressure treatment at 350-380 MPa. This invention achieves uniform distribution and performance optimization of the formulation components without damaging the activity of heat-sensitive components through precise coupling of premixing strength and ultra-high pressure modification parameters. Experiments show that the obtained formulation has an adenosine retention rate ≥96%, a dissolution rate ≥85% after 5 minutes, and excellent moisture resistance and mechanical strength, solving the technical problems of large activity loss, easy moisture absorption, and slow dissolution in traditional formulations.

This invention relates to the field of coating technology and discloses a wear-resistant thin-film waterborne coating and its preparation method. The waterborne coating of this invention comprises 100 parts by weight of waterborne polyurethane, 5-25 parts by weight of sodium sulfonate modified cellulose, 0.6-1 parts by weight of defoamer, 3-5 parts by weight of film-forming aid, 5-8 parts by weight of pigments and fillers, and 1.4-2.3 parts by weight of dispersant. The modified cellulose contains hydrophilic groups of sodium sulfonate, which improves the water solubility of cellulose, resulting in better dispersibility in the waterborne coating, no precipitation, and excellent storage stability of the coating. Furthermore, the microcrystalline cellulose is uniformly dispersed in the waterborne coating, providing excellent reinforcement to the polyurethane film. Simultaneously, the cellulose contains rigid phenylmaleimide rings, exhibiting high structural stability and strength, which is beneficial for improving the impact resistance, hardness, and wear resistance of the coating film.

An aqueous topical skincare composition that comprises one or more skin active agents, such as bakuchiol; microcrystalline cellulose; and a film forming polymer blend, wherein the polymer blend is a combination of acrylates copolymer and acrylates / vinyl acetate copolymer.

The application provides cross-linked esterification modified microcrystalline cellulose and a preparation method thereof, wherein the agglomeration of the microcrystalline cellulose is improved by a double modification method of cross-linking and then esterification, the prepared cross-linked esterification modified microcrystalline cellulose has nanoscale size and high crystallinity, and has good mechanical properties and biocompatibility, and is particularly suitable for the fields of biological stents, tissue repair, drug delivery and biosensors. The application also uses the cross-linked esterification modified microcrystalline cellulose to prepare a collagen composite matrix, and the collagen composite matrix has better mechanical properties, water absorption properties and spatial structure stability, and brings new choices for biomedical material research and application.