The present invention discloses a
Proteus mirabilis strain and a method for producing S-
equol through
daidzein conversion by using the
Proteus mirabilis strain, wherein the strain is preserved in the China Center for Type Culture Collection on November 13, 2011, and a preservation number is CCTCC M 2011390. In the prior art, the existing technology is difficult to prepare the S-
equol through conversion. With the present invention, the problem in the prior art is solved, and a single function
microorganism strain for directly converting a prochiral compound
daidzein into a chiral
compound S-
equol and a preparation method thereof are provided; and compared with the strictly anaerobic equol conversion strains and the mixing
bacteria conversion in the previous reports, the
Proteus mirabilis LH-52 strain of the present invention is a
facultative anaerobe, and is more suitable for industrial production.