Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

107 results about "Masking agent" patented technology

A masking agent is a reagent used in chemical analysis which reacts with chemical species that may interfere in the analysis. In sports a masking agent is used to hide or prevent detection of a banned substance or illegal drug like anabolic steroids or stimulants. Diuretics are the simplest form of masking agent and work by enhancing water loss via urine excretion and thus diluting the urine, which results in lower concentrations of the banned substance as more of it is being excreted from the body making it more difficult for laboratories to detect.

Method and system for detecting contents of platinum, palladium and rhodium in automobile exhaust purification catalyst and application

The invention provides a method and system for detecting the content of platinum, palladium and rhodium in an automobile exhaust purification catalyst and application, and relates to the technical field of automobile exhaust purification, the method comprises the following steps: crushing, grinding, sieving, performing microwave acidolysis, neutralizing, washing and drying a catalyst sample to obtain dry filter residues; a trapping agent and a fluxing agent are added into the dry filter residues, constant-temperature heating is conducted in inert gas, then cooling forming is conducted, and an alloy button is obtained; blowing ash on the alloy, then adding mixed acid into the alloy, heating the alloy in a water bath at 95 DEG C for 25-35 minutes to obtain a dissolved solution, then adding a masking agent into the dissolved solution, and oscillating to obtain a solution to be detected; and filtering the liquid to be detected, fixing the volume and detecting. According to the method, precise quantification of trace platinum, palladium and rhodium in the complex matrix catalyst can be realized, and the method has a relatively high recovery rate; meanwhile, pollution elements are prevented from being used, and the method is green and efficient and better conforms to the concept of green chemistry.
Owner:JIANGSU ENTRY-EXIT INSPECTION & QUARANTINE BUREAU IND PROD TESTING CENT

Dynamic leaching-spectrophotometric detection method for nutrient release rate in slow-release fertilizer

The invention discloses a dynamic leaching-spectrophotometric detection method for the release rate of nutrients in a slow-release fertilizer, and relates to the field of agrochemical analys.The detection method comprises the following steps that S1, a slow-release fertilizer sample is placed in a leaching column to be leached, and leachate is collected; s2, sequentially adding a masking agent solution and a chromogenic reagent into the leachate, and carrying out chromogenic reaction; s3, pumping the solution into a double-optical-path flow cell, and measuring absorbance values under a target nutrient characteristic absorption wavelength and a background interference characteristic wavelength; s4, calculating the corrected net absorbance; and S5, calculating the nutrient concentration, and drawing a nutrient release kinetic curve. By adopting a dual-wavelength synchronous detection and real-time dynamic subtraction correction algorithm, the method can eliminate system errors of time-varying background chromaticity, so that accurate and reliable absorbance readings can be obtained at the initial stage of nutrient release even if the nutrient concentration in the leachate is very low, thereby ensuring the authenticity of the initial stage of a release curve and improving the accuracy of nutrient release. And initial release kinetic parameters are accurately captured.
Owner:江苏省农产品质量检验测试中心

Method for continuously measuring gold, silver, copper, lead and zinc in gold-based alloy

The invention provides a method for continuously measuring gold, silver, copper, lead and zinc in gold-based alloy, and belongs to the technical field of gold alloy element content detection. According to the method, through combined use of a gravimetric method, an electrolytic method and a titration method, by taking chemical means such as extraction and back extraction, electrochemistry and complex reaction as a theoretical basis, the aim of continuously and accurately measuring gold, silver, copper, lead and zinc in the gold-based alloy can be achieved through one-time sample weighing and sample digestion, the efficiency is improved, the complexity of multiple times of treatment is reduced, and the method is suitable for large-scale popularization and application. The method is accurate and reliable. Different masking agents, buffer reagents, precipitants and the like are selected in a targeted manner to be used in one solution one by one, and the problems that an element method is not applicable, measurement is out of range, and elements interfere with one another are solved.
Owner:CHANGCHUN GOLD RES INST

A method for determining the arsenic content in ores

PendingCN122330065AThioureaMasking agent
This invention discloses a method for determining the arsenic content in ores, belonging to the field of ore element detection technology, comprising the following steps: (1) weighing the ore sample, adding hydrochloric acid-nitric acid mixed acid for acid hydrolysis, then adding hydrofluoric acid and perchloric acid for auxiliary digestion, evaporating to near dryness, and dissolving the residue with hydrochloric acid; (2) adding a thiourea-ascorbic acid-citric acid mixed reducing masking agent to reduce and mask interfering ions; (3) using an atomic fluorescence spectrometer to determine the fluorescence intensity of arsenic in the sample solution, and calculating the arsenic content according to the standard curve. This method achieves accurate and stable determination of arsenic in various ores such as phosphate rock and iron ore by optimizing sample pretreatment conditions, improving the reduction system and matrix interference suppression strategy.
Owner:QINGHAI GEOLOGICAL & MINERAL TESTING CENT

Analysis method for measuring high cobalt content by EDTA (Ethylene Diamine Tetraacetic Acid) complexation back titration method

The invention relates to the technical field of zinc hydrometallurgy, and discloses an analysis method for measuring high cobalt content by an EDTA complexing back titration method, which is based on the following steps: oxidizing Co < 2 + > into Co < 3 + > by using potassium nitrite in an acetic acid medium to form cobalt potassium nitrite precipitate so as to realize separation of cobalt and interfering ions, dissolving the precipitate, complexing with excessive EDTA, and performing back titration by using a zinc standard solution. Xylenol orange is used as an indicator, and determination is completed at room temperature in a hexamethylenetetramine buffer system with the pH value being approximately equal to 5.8. Coexisting ion interference is effectively eliminated through tartaric acid, sodium fluoride, thiourea and other masking agents, the method has the advantages of being easy and convenient to operate, sensitive in end point, high in accuracy and low in cost, and the requirement for conventional analysis of high-cobalt materials can be met.
Owner:GANSU CHANGBA NONFERROUS METALS CO LTD +1

A method for accurately detecting the phosphorus content in high-base copper-phosphorus alloy

This invention provides a precise method for detecting phosphorus content in high-matrix copper-phosphorus alloys, belonging to the field of chemical analysis technology for metallic materials. The detection method of this invention includes the following steps: S1: Sample pretreatment; S2: Sample dissolution and volume adjustment; S3: Solution pretreatment: Nitric acid, hydrochloric acid, and deionized water are added to the solution and boiled to remove volatile impurities; S4: Precipitation formation: Ammonia water is added to the solution to adjust the pH to 8.5-9.5, and ammonium citrate-EDTA masking agent is added; quinomolybdate-limonene precipitant is slowly added under simmering conditions, and boiling is carried out for 10-15 minutes with intermittent stirring to ensure complete phosphorus precipitation; S5: Filtration, washing, drying, and weighing; S6: Calculation of phosphorus content. Compared with existing technologies, this invention, through a unique combination scheme, suppresses the hydrolysis of copper ions and the interference of coexisting elements, enabling precise detection of phosphorus content in high-matrix copper-phosphorus alloys. It has advantages such as strong resistance to matrix interference, high detection accuracy, good reproducibility, wide applicability, low detection cost, and simple operation.
Owner:CHINALCO DAYE COPPER PLATE & STRIP CO LTD

A ferric trivalent magnetic solid-phase masking agent and a method for quantitatively detecting lead in vegetable products

The application belongs to the technical field of food quality monitoring, and particularly relates to a ferric magnetic solid-phase masking agent and a quantitative detection method for lead in vegetable products. The ferric magnetic solid-phase masking agent is prepared by the following method: S1, performing carboxylation on the terminal amino group of DFO to obtain DFO-COOH; S2, coating a SiO2 layer on the surface of Fe3O4 magnetic core to obtain Fe3O4@SiO2; S3, modifying the Fe3O4@SiO2 by amination to obtain Fe3O4@SiO2-NH2; and S4, coupling Ac-DFO with Fe3O4@SiO2-NH2 to obtain Fe3O4@SiO2-DFO. The three hydroxamic acid groups of DFO are combined with Fe 3+ to form a stable chelate, and Fe 3+ can be removed through magnetic separation, the removal rate is increased to more than 99%, and the quantitative detection of lead ions is further faster and more accurate in combination with mature immunochromatography technology.
Owner:HANGZHOU HAIRUN TAIHE TESTING TECH CO LTD +1

Digestion device for detecting COD (Chemical Oxygen Demand) in high-chlorine wastewater

The invention relates to the technical field of digestion devices, and provides a digestion device for detecting COD in high-chlorine wastewater, the digestion device comprises a base, a fixing groove is formed in the base, a heating plate is fixedly arranged at the bottom of the fixing groove, the digestion device further comprises a support frame, a water sample bottle, a sealing cover, a lifting mechanism, a liquid adding mechanism and a stirring mechanism, and the support frame is fixedly arranged on the base; the water sample bottle is arranged in the fixing groove in a sliding mode, the sealing cover is arranged on one side of the supporting frame, the lifting mechanism is arranged between the supporting frame and the sealing cover and used for adjusting the height of the sealing cover, the liquid adding mechanism is arranged on the supporting frame and used for adding a high oxidizing agent, a catalyst and a masking agent into the water sample bottle, and the stirring mechanism is arranged on the sealing cover. The stirring device is used for stirring the water sample, the high oxidant, the catalyst and the masking agent in the water sample bottle. According to the technical scheme, the problem that in the prior art, a water sample, a strong oxidant, a catalyst and a masking agent are mixed unevenly, and consequently the detection precision is affected is solved.
Owner:LEXIN TESTING TECH CO LTD

Pest ant bait compositions and methods

PCT designated stageWO2026035867A1BiocidePest attractantsHuman healthZoology
Compositions and methods for controlling fire ant infestations are described using a pesticide agent combined with a masking agent to overcome resistance of fire ants and increase insecticidal acceptance / efficacy are described. The masking agents used in preparing the compositions and methods of using them described are widely used ingredients not expected to affect human health.
Owner:THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES +1

Method for detecting content of aluminum oxide in high-aluminum material

The invention discloses a method for detecting the content of aluminum oxide in a high-aluminum material, based on the principle of EDTA complexometric titration, EDTA and aluminum ions form a stable complex (1gK = 16.1) in a buffer system with the pH value of 6.0, and the end point is judged according to the color change (brilliant yellow-purplish red) of an indicator, the method has the advantages that insoluble substances such as aluminum nitride can be completely decomposed by adopting alkali fusion pretreatment of YST 575.1, and full release of aluminum elements is ensured; by combining a GB / T 6900 titration system and optimizing a buffer condition and a masking agent, interference of iron (III), calcium, magnesium and the like is effectively overcome, so that the method has high accuracy and strong anti-interference performance (can tolerate Cl <-> of less than or equal to 3.5% and Fe of less than or equal to 1.8%), and is suitable for detection of aluminum ash residue recycling products with complex components.
Owner:DONGGUAN XINDONGXIN ENVIRONMENTAL PROTECTION INVESTMENT CO LTD +1

Soluble leucine-containing mixture with reduced bitterness and application of leucine-containing mixture

The invention discloses a leucine-containing dipeptide mixture easy to dissolve and reduced in bitterness as well as a preparation method and application of the leucine-containing dipeptide mixture. The mixture comprises the following components in percentage by mass: not less than 90% of alanyl-leucine, 0-5% of free leucine, less than 1% of water and not more than 0.10% of other impurities. The solubility of the mixture at room temperature reaches up to 500 g / L, the mixture is kept transparent and free of precipitates, the bitterness is reduced by 65% or above compared with leucine, the taste can be improved without a taste masking agent, and the mixture is suitable for sports nourishment and functional food. According to the preparation method, an enzyme catalysis reaction is adopted, and the steps of solid-liquid separation, pH adjustment, crystallization, nanofiltration concentration, drying and the like are performed, so that the total yield is not lower than 90%, the purity is not lower than 99.5%, and high solubility, low bitter taste, instant solubility and environmental friendliness are achieved; and the method has a wide industrial application scene.
Owner:INNOBIO CORP LTD

Bitterness masking agent for potassium chloride

To provide a new bitterness masking agent of potassium chloride, and to provide a production method or the like including the masking agent.SOLUTION: The bitterness masking agent of potassium chloride contains Balsam Peru essential oil as an active ingredient. Here, it is preferable to further contain at least one or more selected from the group consisting of arginine, glutamic acid, lysine and citrulline. It is also preferable to further contain at least one selected from the group consisting of acetoin, diacetyl, and 2, 3-pentanedione.SELECTED DRAWING: None
Owner:NISSIN FOODS HOLDINGS CO LTD

Masking agent for off-flavors and off-odors derived from soy protein, method for masking off-flavors and off-odors derived from soy protein, and method for producing soy protein processed foods.

To provide a masking agent for off-flavors and off-odors derived from soy protein that can reduce off-flavors and off-odors derived from soy protein, a method for masking off-flavors and off-odors derived from soy protein, and a method for producing soy protein processed foods. [Solution] A masking agent for off-flavors and off-odors derived from soy protein, which contains yeast extract and fermented flavor liquid.
Owner:ORIENTAL YEAST

Gallium and germanium ion flotation separation method

The invention discloses a gallium and germanium ion flotation separation method in the technical field of hydrometallurgy, and aims to solve the problems of poor selectivity and low recovery rate when low-concentration gallium / germanium is recovered from a high impurity ion background solution in the prior art. Efficient separation and enrichment of target ions are achieved through the processes of roughing, concentration and scavenging. Wherein a masking agent is added in the concentration stage to deeply purify foam products, and a collecting agent is added in the scavenging stage to maximize the recovery rate. According to the method disclosed by the invention, the simplification and synergistic interaction of the process are realized through the orderly addition of the functional agent and the coupling of the flotation process, the gallium / germanium ion flotation recovery rate can be stabilized at 95% or above within the wide range of pH 1.0-12.0, the key impurity ion entrainment rate is lower than 2%, and the technical problem of loose metal ion flotation separation under a complex system is fundamentally solved.
Owner:CHINA UNIV OF MINING & TECH

Anionic polyacrylamide solution as well as preparation method and application thereof

The invention belongs to the technical field of wastewater treatment, and particularly relates to an anionic polyacrylamide solution as well as a preparation method and application thereof. The anionic polyacrylamide solution comprises anionic polyacrylamide, a stable masking agent, a viscosity reducer and water, the stable masking agent comprises glycerol and a substance A; the substance A comprises at least one of urea, sodium polyacrylate, zeolite and a complexing agent; the viscosity reducer comprises at least one of citric acid and citrate. According to the stable masking agent, specific substances are compounded, namely, glycerol and at least one of urea, sodium polyacrylate, zeolite and a complexing agent are compounded, and specific viscosity reducers are combined, so that the anionic polyacrylamide solution has good stability, and good sewage and sludge treatment effects are achieved.
Owner:SHENZHEN SHENSHUI WATER RESOURCES CONSULTING CO LTD

Ambroxol orally disintegrating film composition, method of preparation and use thereof

The application provides an ambroxol oral dissolving film composition, a preparation method and application thereof. The ambroxol oral dissolving film composition comprises an active drug, a film forming material and a taste masking agent, and the active drug is 2-amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl) benzylamine and / or a pharmaceutically acceptable salt thereof, for example, ambroxol hydrochloride. The ambroxol oral dissolving film composition provided by the application has the advantages of thin thickness, good taste, stable properties, immediate dissolution in the oral cavity without drinking water, and fast oral absorption speed. Moreover, the ambroxol oral dissolving film composition has the advantages of simple process, high drug loading, good drug content uniformity, and good market prospect.
Owner:SHANGHAI BOCIMED PHARMA CO LTD +1

A method and system for detecting the content of platinum, palladium and rhodium in an automobile exhaust purification catalyst, and application thereof

This invention provides a method, system, and application for detecting platinum, palladium, and rhodium content in automotive exhaust purification catalysts, relating to the field of automotive exhaust purification technology. The method includes the following steps: pulverizing, grinding, and sieving the catalyst sample; microwave acid hydrolysis; neutralization, washing, and drying to obtain a dry filter residue; adding a collector and flux to the dry filter residue; heating at a constant temperature under an inert gas atmosphere; and then cooling and shaping to obtain an alloy clip; blowing the alloy clip with soot; then adding a mixed acid; heating in a 95°C water bath for 25-35 minutes to obtain a solution; subsequently adding a masking agent to the solution and shaking to obtain the test solution; and filtering, adjusting the volume, and detecting the test solution. This method can achieve accurate quantification of trace platinum, palladium, and rhodium in complex matrix catalysts with a high recovery rate; it also avoids the use of polluting elements, making it green and efficient, and more in line with the concept of green chemistry.
Owner:JIANGSU ENTRY-EXIT INSPECTION & QUARANTINE BUREAU IND PROD TESTING CENT

Specific probe for detecting perfluorinated compounds in water body and detection method thereof

The invention provides a specific probe for detecting perfluorinated compounds in a water body and a detection method thereof, and belongs to the technical field of detection. The probe provided by the invention is a compound formed by cucurbituril and fluorescein; the detection method provided by the invention comprises the following steps: adding a cucurbituril and fluorescein conjugate into a to-be-detected water sample containing the perfluorinated compounds, carrying out equilibrium reaction for a period of time, and then detecting the fluorescence response intensity in the water body so as to quantitatively evaluate the concentration of the specific perfluorinated compounds in the water sample. Compared with the prior art, the probe equipment provided by the invention is small in size, convenient to carry, capable of simultaneously detecting multiple samples and short in reaction time; the whole material of the probe is green and harmless, and chemical agents such as sulfate which easily cause secondary pollution are not used; other impurity removal and enrichment small columns and complex masking agents do not need to be used. In addition, the detection method provided by the invention has a lower detection limit, the sensitivity and convenience of novel perfluorinated compound detection are remarkably improved, and the application range is wider.
Owner:SICHUAN UNIV

Odor masking agent for processed meat products

PendingJP2026116247ABiotechnologySodium acetate
The present invention provides a masking agent for masking the meaty odor emanating from processed meat products, a method for masking, and a method for producing processed meat products with the masked odor. [Solution] A meat odor masking agent comprising a sucrose fatty acid ester with an HLB value of 13 or higher and sodium acetate, with the amount added to the food being 0.001 to 0.03% by mass and 0.1 to 3% by mass, respectively; a meat product containing the odor masking agent; a method for masking the odor of meat products comprising adding a sucrose fatty acid ester with an HLB value of 13 or higher and sodium acetate to food in amounts of 0.001 to 0.03% by mass and 0.1 to 3% by mass, respectively; or a method for producing meat products with masked odors comprising adding a sucrose fatty acid ester with an HLB value of 13 or higher and sodium acetate to food in amounts of 0.001 to 0.03% by mass and 0.1 to 3% by mass, respectively.
Owner:SAN EI GEN F F I INC

Techniques for toxic metal detection and speciation in aqueous matrices

An in-situ measurement apparatus automatically draws aqueous samples on an intermittent or ad-hoc basis and measures specific metal specie concentration. The apparatus can perform both raw measurement of specific metal specie, as well as processing to convert other species of the same metal to the specific metal specie or to destroy or remove unwanted masking agents (e.g. organics). In one application, “dirty” water from a scrubber is measured for Se(IV) presence (using a renewable voltametric system), both with and without the masking agents present; in addition, selective processing converts other selenium species to Se(IV), permitting assessment of total selenium and measurement of Se(VI) presence. Automated reactions can then be taken to remove detected toxic substances from waste water without excess reliance on treatment chemicals, and so as to ensure that only water complaint with regulatory standards is released into the environment.
Owner:AMS TRACE METALS INC

Masking agent

An agent containing at least one aroma compound selected from the group consisting of E-beta-damascone, S-(2-methyl-3-furyl)ethanethioate, beta-caryophyllene oxide, beta-ionone, 2,5-dihydroxy-1,4-dithiane, methyl anthranilate, S-furfuryl thioformate, 1-isothiocyanate-3-(methylthio)propane, nootkatone, 1,4-dioxacycloheptadecane-5,17-dione, sclareol, and sclareolide is effective for masking an unpleasant smell and for making oral products in which an unpleasant smell is masked.
Owner:AJINOMOTO CO INC

Highly effective sunscreen mousse aerosol and method of making same

PendingCN122351031ASunscreen agentsPreservative
This invention belongs to the field of daily chemical product technology, specifically relating to a high-efficiency sunscreen mousse aerosol and its preparation method. The high-efficiency sunscreen mousse aerosol provided by this invention comprises the following components and their mass percentages: 10%-18% sunscreen agent combination, 1.5%-3% film-forming agent, 2%-5% moisturizer, 1%-2.5% emulsifier, 0.5%-1.5% dispersing aid, 20%-30% propellant, 0.1%-0.3% preservative, 0.05%-0.1% masking agent, and the balance being water; the film-forming agent includes cyclopentamethoxysiloxane and trimethylsiloxysilicate. This invention offers high sun protection efficiency and uniform dispersion of the sunscreen agent, avoiding the severe "whitening" problem of traditional products. It exhibits excellent adhesion to the skin surface, reducing sunscreen film peeling due to sweating and wiping, achieving long-lasting protection. Furthermore, the formula system is stable, forming a thin and breathable protective film after spraying, providing a refreshing and safe feel on the skin.
Owner:GUANGZHOU BIAOBANG CAR CARE IND +1

Method of forming thin film using chemical masking agent, semiconductor device manufactured thereby, and method of manufacturing semiconductor device including same

According to an embodiment of the present invention, a method for forming a thin film using a chemical masking agent comprises: a chemical masking agent supply step for supplying a chemical masking agent to the inside of a chamber in which a substrate is placed, and thereby adsorbing the chemical masking agent to the substrate; a step for purging the inside of the chamber; a metal precursor supply step for supplying a metal precursor, which is a compound containing a hexavalent metal including Mo, to the inside of the chamber to adsorb the metal precursor to the substrate; a step for purging the inside of the chamber; and a thin film forming step for supplying a reactant to the inside of the chamber so that the reactant reacts with the adsorbed metal precursor to form a thin film.
Owner:EGTM CO LTD +1

An oseltamivir composition and a method of preparing the same

The present application relates to a kind of oseltamivir compositions and its preparation method, belong to the field of pharmaceutical preparation.The composition oseltamivir or its pharmaceutically acceptable salt, taste masking agent and optionally other pharmaceutically acceptable auxiliary materials.The taste masking agent is a kind of water-insoluble material or a kind of enteric material.The composition is convenient to take, good taste masking, good taste, fast release, good stability.The preparation method is good in reproducibility, and preparation is simple.
Owner:SUNSHINE LAKE PHARMA CO LTD

Pharmaceutical composition comprising simethicone and alverine citrate, pharmaceutical composition containing simethicone, pharmaceutical composition comprising alverine citrate, and their manufacturing processes.

The invention relates to a pharmaceutical composition, in the form of an orodispersible powder, comprising simethicone and alverine citrate and its manufacturing process; a pharmaceutical composition, in dry form, containing simethicone and its manufacturing process; and a pharmaceutical composition, in granular form, comprising alverine citrate and its manufacturing process. The pharmaceutical composition comprising a mixture of alverine citrate and simethicone according to the invention includes granules composed of simethicone adsorbed onto a powdered solid support; granules containing grains containing alverine citrate, these granules being coated on their external surface with a film of a masking agent; and pharmaceutically acceptable excipients comprising at least one flavoring, and / or at least one acidifier, and / or at least one sweetener, and / or at least one lubricating / anti-aggregating agent, and / or at least one bulking agent.The invention has applications in the pharmaceutical industry.
Owner:LABES MAYOLY SPINDLER R L

Method and system for determining content of calcium and magnesium in zinc solution by chlor-amine method

The application discloses a method and system for determining the content of calcium and magnesium in a zinc solution electrolyzed by a chlorine-ammonia method, and the method comprises the following steps: in a solution with PH equal to 10, taking sodium potassium tartrate and triethanolamine as masking agents, taking acid chrome blue K-naphthol green B as an indicator, titrating with EDTA until the solution is pure blue, and determining the total content of calcium and magnesium; in a strong alkaline solution with PH equal to or greater than 12, taking triethanolamine as a masking agent, taking a calcium indicator as an indicator, titrating with EDTA until the solution is pure blue, and determining the content of calcium. The method can accurately determine the content of calcium and magnesium in the zinc solution electrolyzed by the chlorine-ammonia method, is used for guiding the formula of a production raw material, and can timely remove calcium and magnesium in the solution, so that the production is not seriously affected.
Owner:YUANLING SHANNENG ENVIRONMENTAL PROTECTION TECH CO LTD

Epinastine hydrochloride oral soluble film composition as well as preparation method and application thereof

The invention discloses an epinastine hydrochloride oral soluble film composition as well as a preparation method and application thereof. The invention provides an epinastine hydrochloride oral soluble film composition. The epinastine hydrochloride oral soluble film composition comprises an active medicine, a film forming material and a taste masking agent, the active drug is one or more of 3-amino-9, 13-dihydro-1H-dibenzo [c, f]-imidazo [1, 5-a] azepine hydrochloride as shown in a formula I and a solvate of the 3-amino-9, 13-dihydro-1H-dibenzo [c, f]-imidazo [1, 5-a] azepine hydrochloride. The epinastine hydrochloride oral soluble film composition has the advantages of being thin in thickness, rapid in disintegration, stable in property, good in mechanical property, good in taste, capable of being instantly dissolved in the oral cavity without drinking water and high in oral absorption speed, and is uniform in appearance, good in flexibility, simple in process, free of sedimentation in the preparation process of film liquid and suitable for large-scale production. The content uniformity meets the requirements, and the drug loading capacity is high.
Owner:SHANGHAI BOCIMED PHARMA CO LTD +1