287 results about "Separation column" patented technology

The invention relates to the technical field of chromatographic detection and material characteristic analysis, and discloses a multiphase chromatographic analysis system and method.The multiphase chromatographic analysis system comprises a multiphase sample injection module, a multi-field cooperative regulation and control separation column module and a plurality of separation chromatographic columns which are sequentially connected, and the separation chromatographic columns comprise partitions and are installed in a column box in an end-to-end connection mode; a temperature gradient field, an electric field gradient field, a controllable electromagnetic field and a fluid power field; and a multi-modal detection module, a data acquisition and control module and an auxiliary module. Through the brand-new multi-phase sample injection module, the multi-field coordinated regulation and control separation column module and the multi-mode detection module, direct input of detected objects in different phase states can be met, and phase state conversion is carried out according to needs, so that the phase state compatibility of the analysis system to the detected objects is obviously enhanced; and different components can be obviously separated according to different boiling points, migration speeds and magnetic susceptibilities by combining multi-field synergistic separation, so that the chromatogram is more accurate.

The present invention belongs to the field of radioactive isotope preparation. Disclosed is a method for preparing carrier-free lutetium-177 by means of multistage continuous separation and purification. The method comprises: heating and dissolving a 177Lu-containing target material 176Yb2O3 which is subjected to neutron irradiation, so as to prepare a first nitric acid solution containing the target material; after filtering said first nitric acid solution and loading same onto a separation column, using a second nitric acid solution and a third nitric acid solution to wash the separation column, and allowing an effluent to pass a purification column and then loading same onto a conversion column; and using the first nitric acid solution and a hydrochloric acid solution to wash the conversion column. The method for preparing carrier-free lutetium-177 by means of multistage continuous separation and purification provided in the present invention has simple processes, is easily operable, implements multistage continuous separation for preparation of carrier-free lutetium-177, remarkably improves the recovery rate of lutetium-177, and offers a feasible and efficient method for high-efficient preparation of carrier-free lutetium-177.

A liquid chromatograph includes a controller, a liquid feeding unit, a first separation column, a second separation column, a first switch valve, and a second switch valve. Each of the first switch valve and the second switch valve has two states. The controller combines the two states of each of the first switch valve and the second switch valve to form first to third forms in a flow path including the first switch valve and the second switch valve, thereby providing SARA analysis using the first separation column and the second separation column in the fractionating liquid chromatograph.

The invention relates to the technical field of automatic control, and discloses a PLC-based seawater multi-nuclide separation automatic control method and system, and the method comprises the steps: obtaining analysis task parameters, such as a sample volume, a target nuclide type sequence, and the like; converting the data into an internal execution formula containing a precise time sequence and an actuator action sequence through PLC internal compiling logic; the method comprises the following steps: performing online pretreatment on original seawater based on sensor feedback of pH value, flow velocity and the like to obtain a sample flow with optimized conditions; according to system state data, multi-nuclide sequential adsorption is realized, and a separation column loaded with target nuclide is obtained; and sequentially eluting by using different eluents, and collecting to obtain the purified single nuclide component. The whole process runs in a full-automatic mode, the risk that experimenters are exposed to the radioactive environment is greatly reduced, errors caused by manual operation are effectively eliminated, and high consistency and traceability of analysis data of different batches and different monitoring mechanisms are guaranteed.

The present invention relates to the field of separation, analysis and detection technology, and specifically to a method for quickly detecting lactic acid in liquor Daqu and fermented grains using an ion mobility spectrometer. The ion mobility spectrometer comprises an ion mobility tube, which comprises an ionization zone and a drift zone. The ionization zone comprises a photoionization source, a vacuum pump interface, a chemical dopant interface, and an injection interface. A drift gas inlet is provided at the tail of the ion mobility tube. The vacuum pump interface, the chemical dopant interface, and the injection interface are sequentially arranged in a vertical direction of the central axis of the ion mobility tube, and the injection interface is connected to an injection device. The ion mobility spectrometer is used for detection in negative ion mode, and the sample is extracted with isopropanol as an extractant to achieve high-sensitivity detection of lactic acid. The method of the present invention has simple sample pretreatment, saves time, does not require filtering operation, and will not contaminate the detector or block the separation column. The sample is extracted with isopropanol, which can not only regulate the air reagent ion peak, but also solve the corrosion effect of lactic acid on the entire system material.

The invention discloses a teaching experiment device for dendrobium officinale flavone extraction and concentration, and the device comprises a separation column which is vertically fixed on the side surface of a supporting frame, and the separation column is internally provided with a reaction liquid; a plurality of groups of sampling wheels are vertically arranged on the side, away from the supporting frame, of the separation column, the axes of the sampling wheels are vertically arranged, a driving assembly is arranged on the axis sides of the sampling wheels, and sampling grooves are formed in the upper portions of the sampling wheels; according to the invention, the sampling wheels are vertically arranged on one side of the chromatographic column, and each sampling groove can accurately enter different depth areas of the chromatographic column, so that sampling is carried out in different time periods of the concentration process. According to the device, a closed concentration environment and an automatic sampling mechanism are adopted, the problem of potential safety hazards caused by frequent opening and closing of the device is avoided, meanwhile, the experiment operation difficulty is reduced, the device is particularly suitable for being used in teaching experiments, and the safety of students can be effectively protected.

The invention relates to a separation column module (1) for a chromatograph, in particular a gas chromatograph, comprising: a chromatographic separation column (2); a temperature control device (3) on the separation column (2) for generating a temporal and / or spatial temperature profile (6) along the separation column (2); and a control unit (4) which is connected to the temperature control device (3) and is designed to electronically control the temperature control device (3), wherein the separation column (2) forms at least one winding (9) and a receiving region (10) inside the at least one winding (9), in which receiving region (10) the control unit (4) is at least partially arranged, wherein the separation column (2) is divided into a plurality of segments (22) and each segment (22) is assigned to its own temperature control element (23) of the temperature control device (3), wherein the temperature control elements (23) are designed to heat and / or cool the segment (22) assigned to them. The invention also relates to a chromatograph (29) having such a separation column module (1).

The invention relates to the technical field of extraction separation, and provides an extraction separation device which comprises a body, the body is provided with a sample disc, a reagent bottle and an extraction column disc, the extraction column disc is provided with a plurality of separation columns, and the separation columns are used for selective adsorption and separation of uranium matrixes and impurity elements; the first mechanical arm is arranged on the body; the liquid adding assembly is arranged on the first mechanical arm, and the liquid adding assembly is used for taking liquid from the reagent bottle and executing liquid adding operation; the pipetting assembly is arranged on the first mechanical arm, and the pipetting assembly is used for sampling from the sample disc and executing sample loading operation; the second mechanical arm is arranged on the body; the pressurizing device is arranged on the second mechanical arm and is used for executing sealing pressurizing operation on the separation column; the receiving assembly is arranged on the body, can move relative to the body and is used for collecting the sample solution and the waste liquid. A plurality of problems during manual separation operation are solved, and the whole process of sample loading, leaching, elution, receiving, constant volume, waste liquid collection and the like is automatically completed.

A gas chromatograph (100) for analyzing content of a gas sample includes a sample gas inlet configured to receive the gas sample and a carrier gas source (114) which provides a carrier gas. A separation column (120) is configured such that individual component gases in the sample gas separate as they move through the separation column (120). A first sample valve (112) is coupled to the sample gas inlet, the carrier gas source (114) and to a sample loop which is configured to contain a sample volume of the gas sample. The first sample valve (112) injects the sample volume into the separation column (120) and individual component gases in the sample gas separate as they move through the separation column (120). A detector (122) detects a concentration of an individual component gas as a function of a sensitivity of the detector (122). A controller (108) changes a response factor of the gas chromatograph by changing at least one of the sensitivity of the detector (122) and the sample volume.

An object of the present invention is to provide a liquid chromatograph and an analysis method in which a first mounting portion capable of mounting a packed column and a second mounting portion capable of mounting a chip column having a flow path functioning as a separation column on a substrate are housed in a column oven. Designation of the temperature of the column oven is received by a designated temperature receiving unit. When no chip column is mounted on the second mounting portion, the upper limit temperature of the column oven is set by a setting unit to a first temperature. Further, when a chip column is mounted on the second mounting portion, the upper limit temperature of the column oven is set by the setting unit to a second temperature lower than the first temperature. When the temperature received by the designated temperature receiving unit is equal to or lower than the upper limit temperature set by the setting unit, the temperature of the column oven is adjusted by a temperature adjusting unit to the received temperature.

The venturi-type scrubber may be used in conjunction with the removal of solids and quench gas-phase reaction products from the gas-phase reaction products. A method can include: providing a reaction product comprising a hydrocarbon gas and a solid; introducing the reaction product into a venturi type scrubber; introducing a scrubbing fluid into the venturi-type scrubber, wherein the scrubbing fluid is at a lower temperature than the reaction product; generating, by the venturi scrubber, a heterogeneous product comprising a scrubbed reaction product and a waste scrubbing fluid, the scrubbed reaction product comprising the hydrocarbon gas, and the waste scrubbing fluid comprising the scrubbing fluid and the solids; and separating the hydrocarbon gas from the multiphase fluid. A system may include a reactor; a venturi-type scrubber having a first inlet fluidly connected to the reactor and a second inlet configured to receive a scrubbing fluid; and a separation column configured to receive a multiphase stream from the venturi scrubber after solids are removed.

A liquid chromatograph of the present application can continuously perform separation and fractionation of a plurality of samples and includes a separation flow path provided with a liquid feed pump, a separation column, and a detector; a plurality of liquid handlers each including an injection section that performs an injection operation when introduced into the separation flow path and a fractionation section that performs a fractionation operation when introduced into the separation flow path; a selector that selectively switches the liquid handlers introduced into the separation flow path; and a controller that controls the operations of the liquid handlers and the selector and introduces the plurality of liquid handlers into the separation flow path in a prescribed order and causes each liquid handler to perform the injection operation and the fractionation operation, sequentially performing separation and fractionation of a plurality of samples assigned to each of the liquid handlers, the controller causing each of the liquid handlers to perform a preparation operation for performing the injection operation during introduction of the other liquid handler into the separation flow path and to perform the injection operation immediately after being introduced into the separation flow path.

The embodiment of the invention discloses a method and a device for preparing 212Pb based on 226Ra, and the method comprises the following steps: carrying out reactor irradiation treatment on a target material containing 226Ra to obtain an irradiated target material; and dissolving the irradiation target material to obtain a target material dissolving solution. The target material dissolving solution is placed in a first separation column to be subjected to first acid leaching treatment, a Th-containing adsorption column is obtained, and the first separation column is used for adsorbing Th. And carrying out second acid leaching treatment on the Th-containing adsorption column to obtain a Th-containing eluent. And carrying out standing treatment on the Th-containing eluent to obtain a standing solution containing 228Th. And the standing liquid containing 228Th is placed in a second separation column to be subjected to third acid leaching treatment, eluant containing 212Pb is obtained, and the second separation column is used for separating lead.

The invention relates to the field of chemical equipment, and discloses a production device and method of 1, 1-difluoroethane. The production apparatus comprises: a reactor; a reflux tower and a first condenser, a feed inlet and a liquid phase outlet of the reflux tower are connected with the reactor, a gas phase outlet of the reflux tower is connected with the first condenser, and a gas phase outlet of the first condenser is connected with the reactor; the separation tower is connected with a liquid phase outlet of the first condenser, a liquid phase outlet of the separation tower is connected with the reactor, a gas phase outlet of the separation tower is connected with the second condenser, a gas phase outlet of the second condenser is connected with the reactor, and a liquid phase outlet of the second condenser is connected with the separation tower; and the post-treatment system is connected with the liquid phase extraction port of the separation tower. The production device can be used for separating and recycling hydrogen fluoride, reducing the content of hydrogen fluoride in the product, eliminating the consumption of fresh water and alkali liquor caused by a water alkali washing process, avoiding the generation of aqueous hydrofluoric acid with low additional value, and eliminating a heavy component removal tower.

The present application relates to a multi-column combined low-pressure column chromatography device and a process for purifying (S)-1-(carbamoyl)methyl-4-hydroxy-2-pyrrolidinone reaction liquid. It comprises a sample column (1), a rough separation column (2), a fine separation column (3), a target product collection tank (4), a waste mobile phase collection tank (5), a waste mobile phase regeneration system (6), a mobile phase storage tank (7), a cleaning liquid storage tank (8), a waste liquid tank (9), a pump (10), and a valve (11). The device cooperates with a specific process to significantly improve the column chromatography separation efficiency and impurity removal capacity, completely separates the impurities with similar polarity, realizes high productivity and high impurity removal capacity under the condition of severe load overload of the chromatographic column, and correspondingly reduces the use amount of the mobile phase by more than 60%. The purity of the crude product after the column can reach more than 99%, and the yield is stable at more than 85%.

A method of controlling a liquid chromatograph that estimates the maximum value of the pressure reached during measurement before actually measuring a sample. The method includes a pump having a gradient function that feeds liquid while changing the composition of a plurality of eluents, according to gradient liquid feeding conditions, a sample filling unit for filling a sample, a separation column, an analysis flow channel connecting the pump to the separation column, and a pressure sensor which detects a pressure within the analysis flow channel during liquid feeding by the pump. A maximum pressure presumed during measurement is calculated based on an initial pressure as a pressure within the analysis flow channel when the pump starts feeding liquid and the gradient liquid feeding conditions and that when the maximum pressure presumed is determined to be a predetermined upper pressure limit, the sample filling is not performed.

This process for cryogenic air separation and the respective air separation plant use a high-pressure column (101), high-pressure column (101) and low-pressure column (102), a usual main condenser (103) and a crude argon column (107a / b / c) connected to the low-pressure column (102) at a first intermediate position, the argon transition. A second nitrogen top gas (40) is withdrawn from the top of the low-pressure column (102) and used as recycle nitrogen (41, 42, 44,47,48), recycled nitrogen (48) being introduced in gaseous form (48) into the high-pressure column (101) and / or into the main condenser (103) and / or into a bottom reboiler of a separation column (81,77). The air separation plant further comprises a medium-pressure column (104) being operated at intermediate pressure and fed by a first oxygen-enriched fraction (33, 34) from the high-pressure column (101) is introduced as feed into the medium-pressure column (104). A portion (38) of the argon transition fraction is introduced as heating medium into a bottom evaporator (106) of the medium-pressure column (104). A first portion (362) of the third nitrogen top gas (361) from the medium-pressure column (104) in gaseous form, warmed in the main heat exchanger (9) und finally withdrawn as gaseous nitrogen product (UHPGAN). A second portion (53) of the third nitrogen top gas (361) is liquefied in the top condenser (105) of the medium-pressure column (104) and used as reflux in the medium-pressure column (104). A second oxygen-enriched fraction is withdrawn from the medium-pressure column (104) and introduced into the top condenser (105) of the medium-pressure column (104) as cooling medium (38). At least a portion of the oxygen-enriched gas (36) produced in the top condenser (10) is introduced into the low-pressure column (102) at a second intermediate position at least 25 theoretical trays above the first intermediate position.

The invention discloses a method for preparing the 68 Ge method. The method comprises the following steps: S1, preparing a metal gallium nickel alloy target, and then dissolving it after irradiation; the structure of the metal gallium nickel alloy target is as follows 1) or 2): 1) at least two layers, including a metal base layer and a metal gallium nickel alloy layer; 2) at least three layers, including a metal base layer, a metal protective layer and a metal gallium nickel alloy layer; S2, passing the dissolved solution into a double series chromatographic column for separation and purification, and collecting the 68 Ge solution; S3, the obtained 68 The Ge solution was passed into 68 Ge / 68 In the Ga generator, when 68 After Ge is fully adsorbed, the eluent is used to wash the Ge at preset intervals. 68 Ge / 68 The separation column in the Ga generator is eluted, and the eluted eluent is collected to obtain 68 Ga products. The present invention 68 The separation and purification process of Ge has clear ideas, simple operation, and is easy to realize automated separation and purification, and can obtain high purity and radioactive concentration. 68 Ge.

A unit for producing argon by cryogenic distillation, suitable for connection to a double air separation column consisting of first and second columns interconnected thermally, comprises an argon separation column surmounted with a top condenser and a denitrogenation column, means for withdrawing an argon-rich and nitrogen-depleted product (LAR) at the bottom of the denitrogenation column, means for connecting the top of the argon separation column to the denitrogenation column, means for sending a top gas from the argon separation column to the atmosphere, means for withdrawing a nitrogen-rich fluid from the top of the denitrogenation column, an analyser for measuring the nitrogen content at the top of the argon separation column, and means for opening and closing the means for connecting the top of the argon separation column to the denitrogenation column depending on the nitrogen content detected by the analyser.

The present invention realizes a liquid chromatograph device that can remove bubbles during the preparation action when the device is started without complicated operations. The liquid chromatograph device includes a liquid delivery pump (1) for delivering a solvent, a syringe (53) for injecting a sample into the solvent delivered by the liquid delivery pump (1), a separation column (54) for supplying a solvent and a sample through the syringe (53) and separating the sample according to components, a detector (55) for detecting the components supplied from the separation column (54), a pressure sensor (51) for measuring the pressure in the solvent flow path of the liquid delivery pump (1), and a controller (50) for controlling the action of the liquid delivery pump (1). The controller (50) controls the bubble removal action in the solvent flow path performed by the liquid delivery pump (1), i.e., the purge action, and determines whether the pressure change in the solvent flow path measured by the pressure sensor (51) during the purge action is greater than a specified change, and when the pressure change is greater than the specified change, the bubble removal action is completed.

The utility model discloses an exchange resin separation device for measuring gallium in rare earth ore, which comprises separation support frames, a partition plate A and a partition plate B are mounted between the separation support frames, a resin separation device is connected between the partition plate A and the partition plate B in a penetrating manner, a separation column is mounted at the top of the partition plate A, and a separation column is mounted at the bottom of the separation column. The bottom of the separation column is connected with a liquid storage cup, the bottom of the liquid storage cup is provided with a column body, the column body is internally provided with a resin layer, the bottom of the resin layer is provided with a filter padding, and one side of the column body is connected with an overflow pipe. The exchange resin separation device for measuring the gallium in the rare earth ore comprises a separation column and a separation column bracket, the separation column is composed of a liquid storage cup, a column body, a resin layer, a filter padding and an overflow pipe, and the liquid storage cup is firstly connected with the column body and used for temporarily bearing a solution to be separated.

The utility model discloses an isotope separation and purification column frame which comprises a limiting disc, an inserting disc and a stand column, the limiting disc can rotate on the outer side of the stand column; a plurality of strip-shaped grooves are formed in the limiting disc in the circumferential direction, and a plurality of inserting holes corresponding to the strip-shaped grooves are formed in the inserting disc; connecting holes corresponding to the inserting holes are formed in the waste liquid collecting box, and guide pipes are connected between the connecting holes and the corresponding inserting holes; and a high-pressure spray head is arranged at the upper end of the hollow guide pipe, extends to the upper end of the limiting disc and corresponds to one strip-shaped groove. According to the utility model, the residual liquid in the separation column directly drops into the waste liquid collection box, so that the chemical residual liquid is prevented from being exposed; the separation column can be cleaned without being picked up and transferred.

A method of introducing a sample into a separation column includes introducing the sample into a trap column, isolating the trap column from ambient atmosphere and pressurizing the trap column to a first pressure while the trap column is isolated from ambient atmosphere, providing a fluid connection between the trap column and the separation column after pressurizing the trap column to the first pressure, supplying the sample from the trap column to the separation column.

The present invention relates to a column oven and a gas chromatograph. The column oven (2) comprises: an inner shell (10) having an inner space (11) formed therein, the inner space being used to accommodate a separation column (4) for the gas chromatograph and to regulate the temperature of the separation column (4); a temperature regulating device (12) disposed in the inner space (11) for regulating the temperature of the inner space (11); and a heat insulating material layer (14) surrounding the outer peripheral surface of the inner shell (10) and being composed of a fibrous raw material, the heat insulating material layer (14) comprising: a first layer (18) having a first volume density (ρ1); and a second layer (20) surrounding the outer side of the first layer (18) and having a second volume density (ρ2) lower than the first volume density (ρ1).

The present application relates to a kind of device and method for extracting high-purity chemicals from coal tar wash oil fraction, comprising: naphthalene separation column, methylnaphthalene separation unit, acenaphthene-fluorene-dibenzofuran separation unit;Methylnaphthalene separation unit includes methylnaphthalene separation tower, β-methylnaphthalene subunit and α-methylnaphthalene subunit connected in sequence;Acenaphthene-fluorene-dibenzofuran separation unit includes light removal tower, acenaphthene subunit, dibenzofuran subunit and fluorene subunit connected in sequence;The material outlet of the bottom of naphthalene separation column is connected with methylnaphthalene separation tower;The material outlet of the bottom of methylnaphthalene separation tower is connected with the material inlet of light removal tower.The device provided by the present application can effectively extract target chemicals in coal tar wash oil fraction by reasonable configuration of the device and coupling cooperation between devices, and obtain high-purity products.Compared with existing wash oil extraction chemical technology, it has higher efficiency, wider applicability and better product quality.

The present invention relates to a method in a liquid chromatography system comprising a first separation column, a second separation column, a separation pump upstream of the separation columns, and a detector downstream of the separation columns, wherein the method comprises: detecting a failover activation event with respect to one of the separation columns, wherein the separation column is a non-operational column while the other is an operational column; and operating the liquid chromatography system in a failover mode after detecting the failover activation event. Operating the liquid chromatography system in failover mode comprises: enabling fluid communication between the separation pump, the operational column, and the detector, and preventing fluid communication between the non-operational column and the detector. The present invention also relates to a liquid chromatography system.

The present invention belongs to the technical field of gas stable isotope determination, and provides 15 A pretreatment system and method for gas products of N tracer nitrification-denitrification. The pretreatment system of the present invention uses a chemical trap to remove CO2 and H2O from the gas products of nitrification-denitrification; the first cold trap can remove CO2, H2O, NH3, NO2 and N2O from the gas products of nitrification-denitrification; the oxygen is removed by using a high-temperature reduction furnace; then the trace carbon monoxide, small molecule organic matter and nitrogen are separated by using a separation column; and the residual CO2, H2O, NH3, NO2 and N2O are removed by using a second cold trap. The pretreatment system of the present invention can remove O2, NOx, CO2, H2O and small molecule organic matter from the gas products of nitrification-denitrification, which is beneficial to the accurate detection of N2 in the gas products of nitrification-denitrification.

A gas chromatograph includes a sample gas generator, a separation column configured to separate components of an introduced sample gas, a gas supply source configured to supply a carrier gas to the sample gas generator to carry the sample gas from the sample gas generator to the separation column when the components of the sample gas are analyzed, a controller configured or programmed to acquire an in-analysis usage amount of the carrier gas based on an analysis time for analyzing the components of the sample gas, and a flow rate of the carrier gas supplied from the gas supply source to the sample gas generator, and a display configured to display the in-analysis usage amount acquired by the controller.

Systems for performing two-dimensional chromatography are disclosed. The system includes a first switching valve fluidly coupled to a first separation column. The system includes a second switching valve coupled to a second separation column. The second switching valve is fluidly coupled to the first switching valve. The system includes an input / output valve in fluid communication with the first switching valve and the second switching valve that is configured to direct one or more mobile phases to the first switching valve. The system includes a sampling valve fluidly coupled to the first switching valve that includes at least one fraction capturing device. Methods of separating compounds using the systems are disclosed. Methods of retrofitting existing two-dimensional chromatography systems are also disclosed.

A preparative chromatograph system includes: a chromatograph part including a separation column and a detector; a fraction collector for executing a fractionation collecting operation of dropping and collecting the eluate flowed out from the separation column through a nozzle into a plurality of collection containers; a controller configured to control an operation of the fraction collector based on a preset fractionation collecting condition; an information processing device configured to perform information processing relating to the fractionation collecting operation; and a display. The information processing device is configured to output a chromatogram created based on a signal of the detector to the display in a state where fractionated sections on the chromatogram collected in the plurality of collection containers by the fraction collector and collection information including a collection purpose for which each fractionation section has been collected are added to the chromatogram.