34 results about "Light-addressable potentiometric sensor" patented technology

A light-assisted biochemical sensor based on a light addressable potentiometric sensor is disclosed. The light-assisted biochemical sensor comprises a semiconductor substrate and a sensing layer, which are used to detect the specific ion concentration or the biological substance concentration of a detected solution. Lighting elements fabricated directly on the back surface of the semiconductor substrate directly illuminate the light to the semiconductor substrate, so as to enhance the photoconduction property of the semiconductor substrate. And then, the hysteresis and the sensing sensitivity of the light-assisted biochemical sensor are respectively reduced and improved. In addition, due to its characteristics of integration, the light-assisted biochemical sensor not only reduces the fabrication cost but also has portable properties and real-time detectable properties. As a result, its detection range and the application range are wider.

The invention relates to a carbohydrate lactic acid bacteria metabolism analysis and detection device which comprises a controller, a signal circuit, a light source modulation circuit, an excitation light source, a light addressing potential sensor, a reference electrode and a test cavity, the light addressing potential sensor is fixed at the bottom of the test cavity and is connected with the signal circuit; one end of the reference electrode is inserted into the test cavity, and the other end is connected with the signal circuit to provide bias for the light addressable potential sensor; theexcitation light source is arranged on the back surface of the light addressing potential sensor, is connected with the light source modulation circuit and provides light excitation for the light addressing potential sensor; the light source modulation circuit is connected with the signal circuit and is controlled by the signal circuit to modulate optical excitation; and the controller is in communication connection with the signal circuit and is used for detecting, controlling, recording and processing acquired data. According to the invention, quantitative analysis and detection of carbohydrate lactic acid bacteria metabolism can be realized.

The invention discloses an array optical address potential sensor chip and preparation method thereof. The array optical address potential sensor chip comprises silicone base chip and a plurality of sensitive zones are provided on the front face of the silicone base chip and a front face heavily doped layer is provided on the silicone base chip around the sensitive zones. An oxide layer is mounted above the sensitive zones and the front face heavily doped layer. A chip electrode is set on the thick oxide layer above the front face heavily doped layer. A back face heavily doped layer is set onthe back face of the silicone base chip and an aluminium electrode is set on the back face of the heavily doped layer. The silicone base chip between the sensitive zones is heavily doped and the thick oxide layer grows on the heavily doped layer and the chip electrode is set on the thick oxide layer. The chip can increase the degree of freedom of the coating sensitive membrane and the chip electrode can directly be connected with the external circuit to measure without other electrode. The back face heavily doped layer can form good ohmic contact with the aluminium electrode and silicone basechip. The preparation method uses standard semiconductor technology to ensure the consistency of the chip performance.

The invention discloses a measuring pool for an optical addressing potential sensor, which is composed of a square array (6), a round hole (7) and a square array (8), and the square arrays (6) are arranged at equal intervals on the top of the measuring pool (1) On the cover, the square arrays (8) are arranged at the bottom of the measuring pool at equal intervals, and are aligned up and down with the square arrays on the top cover, in one-to-one correspondence; the solution can be multi-parameterized and multi-parameterized by coating different sensitive films on the silicon wafer. Point measurement can also be applied to the measurement of the concentration distribution of the same solution component in different measurement domains. The overall structure is a standard cuboid, which is simpler in structure than the method of controlling the number of steps of the stepping motor, accurate in addressing, easy to integrate, and easy to operate. The invention solves the disadvantages of complicated peripheral control and manufacturing process, cumbersome operation and inaccurate addressing in the existing optical addressing sensor measuring pool.

The invention discloses a composite feedback light intensity modulation system of an optical address potentiometric transducer. A super-radiation light-emitting dioxide module of the modulation system comprises a super-radiation light-emitting dioxide, a refrigerator and a thermal resistor; a composite feedback light intensity modulation circuit comprises an amplifying and feedback circuit, a last level current amplifier and a tube core temperature detection and control circuit; an output end of the amplifying and feedback circuit is connected with an input end of the last level current amplifier; an output end of the last level current amplifier is connected with the supper-radiation light-emitting dioxide; the super-radiation light-emitting dioxide is connected with a first negative feedback interface of the amplifying and feedback circuit; the thermal resistor is connected with an input end of the tube core temperature detection and control circuit; an output end of the tube core temperature detection and control circuit is connected with the refrigerator; and the super-radiation light-emitting dioxide, the refrigerator and the thermal resistor are in thermal coupling with one another. The light intensity of the composite feedback light intensity modulation system changes along with voltage signals input from the outside proportionally, and has the advantages of low distortion characteristic, long-term stability and temperature stability.

The invention discloses a device and method for detecting the performance of a DNA by using a ZnO nanorod to enhance an optical addressing potential sensor. The device includes a Faraday shielding box, a loading table, a semiconductor laser, an LAPS sensor, a constant voltage device, a phase-locked amplifier, an acquisition card, and a computer. The method includes the steps of making a LAPS chip,modifying the surface of the LAPS chip with the ZnO nanorod, modifying the surface of the LAPS chip with a probe chain DNA, scanning an I-V curve; placing a target DNA in a detection cavity, scanningthe I-V curve, and comparing the performances of the modified and unmodified ZnO nanorods. Label-free detection of the DNA is realized, and the advantages that the time is short, the cost is low, operation is convenient, three-dimensional sites are provided for DNA hybridization, and sensitivity is high are achieved.