169 results about "Potentiostat" patented technology

Electroporation-based therapies (EBTs) employ high voltage pulsed electric fields (PEFs) to permeabilize tumor tissue, resulting in changes in passive electrical properties detectable using electrical impedance spectroscopy (EIS). Currently, commercial potentiostats for EIS are limited by impedance spectrum acquisition time (˜10 s); this timeframe is much larger than pulse periods used with EBTs (˜1 s). Fourier Analysis SpecTroscopy (FAST) is introduced as a methodology for monitoring tissue inter-burst impedance (diagnostic FAST) and intra-burst impedance (therapeutic FAST) during EBTs. FAST is a rapid-capture (<<1 s) technique which enables monitoring of inter-burst and intra-burst impedance during EBTs in real-time. FAST identified a frequency which delineates thermal effects from electroporation effects in measured impedance. Significance: FAST demonstrates the potential to perform EIS, in addition to intra-burst impedance spectroscopy, using existing pulse generator topologies.

Electroporation-based therapies (EBTs) employ high voltage pulsed electric fields (PEFs) to permeabilize tumor tissue, resulting in changes in passive electrical properties detectable using electrical impedance spectroscopy (EIS). Currently, commercial potentiostats for EIS are limited by impedance spectrum acquisition time (˜10 s); this timeframe is much larger than pulse periods used with EBTs (˜1 s). Fourier Analysis SpecTroscopy (FAST) is introduced as a methodology for monitoring tissue inter-burst impedance (diagnostic FAST) and intra-burst impedance (therapeutic FAST) during EBTs. FAST is a rapid-capture (<<1 s) technique which enables monitoring of inter-burst and intra-burst impedance during EBTs in real-time. FAST identified a frequency which delineates thermal effects from electroporation effects in measured impedance. Significance: FAST demonstrates the potential to perform EIS, in addition to intra-burst impedance spectroscopy, using existing pulse generator topologies.

The invention belongs to the technical field of buried pipeline corrosion monitoring, and provides a buried pipeline cathode protection corrosion rate on-line monitoring method and system, and the method comprises the steps: laying a multi-dimensional cooperative monitoring sensor array, collecting sensor data, evaluating the health state of a buried pipeline, and if the buried pipeline is in a healthy state, determining whether the buried pipeline is in a normal state or not; the method comprises the steps that a monitoring area is divided into a plurality of corrosion analysis units in a meshing mode, the corrosion analysis units conduct corrosion rate modeling, historical corrosion rate sequences of the corrosion analysis units are sorted, a multi-layer LSTM network model is trained to predict the corrosion rate, and a predicted corrosion rate sequence is obtained; and estimating the end point predicted wall thickness of the buried pipeline in each corrosion analysis unit in the prediction time period and analyzing the dispersion, if the dispersion is high, screening the risk corrosion unit, analyzing the end point predicted wall thickness of the risk corrosion unit or the corrosion analysis unit, judging whether to trigger the regulation and control of the constant potential rectifier, and if the regulation and control of the constant potential rectifier are triggered, judging whether to trigger the control of the constant potential rectifier. And if so, regulating and controlling the output current of the constant potential rectifier.

Provided is a potentiostat-based electrochemical sensor detection device. The device comprises: a digital-to-analog converter (DAC) configured to receive a digital signal from a waveform generator and digital logic and output an analog signal corresponding to a reference voltage; a control amplifier (CA) configured to receive the analog signal corresponding to the reference voltage and apply the reference voltage to a reference electrode (RE); a gain-boosting current mirror configured to copy a sensor current of an electrochemical sensor and output a copied sensor current; a transimpedance amplifier configured to convert the copied sensor current into a voltage signal; a low-pass filter configured to block a high-frequency band signal component of the voltage signal; and an analog-to-digital converter (ADC) configured to perform digital signal processing on a signal having passed through the low-pass filter, wherein at least one of the gain-boosting current mirror and the transimpedance amplifier employs a dynamic element matching (DEM) technique using a plurality of choppers and a plurality of DEM clock signals.

Techniques for determining microbiological corrosion include flowing a mixed-phase wellbore fluid from at least one tank into a volume of a reactor tank of a microbiological corrosion reactor; controlling a multi-channel potentiostat coupled to a three-electrode cell assembly positioned in the volume, the three-electrode cell assembly including a working electrode, a counter electrode, and a reference electrode, where each of the working electrode, the counter electrode, and the reference electrode is positioned in the volume to contact the mixed-phase wellbore fluid; based on controlling the multi-channel potentiostat, activating the working electrode in the mixed-phase wellbore fluid in the volume; and determining, based on activating the working electrode, a corrosion rate of at least one of the working electrode or a target coupon positioned within the mixed-phase wellbore fluid in the volume.

The invention discloses a sewage treatment equipment state supervision system, belongs to the technical field of sewage treatment, and solves the problems that the sewage contains reducing sulfides and competes with denitrifying bacteria for electron donors, so that the COD in an anoxic zone is sufficient, the nitrate reduction rate is low, a false carbon source sufficient trap with inhibited denitrification occurs, but the sulfide is easy to oxidize, and the potential safety hazard is caused. And a sampling detection result is distorted and is difficult to identify. According to the invention, sewage is measured in an anoxic zone through a probe interface module, under the scheduling of a time division control module, a constant potential rectifier module excites sulfide characteristic oxidation current in a DPV time period, a logarithmic current detection module captures a peak value and integrates a charge quantity, an impedance detection module measures phase offset in an EIS time period, a signal processing module fuses characteristic values, and a temperature compensation module eliminates errors. The reference electrode protection module ensures signal fidelity, outputs sulfide concentration and electron competition index, starts a dosing system when the concentration exceeds the limit, and prevents sampling oxidation distortion in the whole process.

The invention discloses a method for cathode protection of a natural gas pipeline, and the method achieves the high-precision reasoning of the state of a target monitoring point through the spatial sequence coding and multi-scale hierarchical interaction of the data of a plurality of monitoring points along the line. Further calculating a proportionality coefficient between a reasoning value and a measured value to dynamically quantify the confidence coefficient of the input data; then, the input data confidence coefficient serves as a weight to directly participate in PID parameter modulation, so that a PID controller can conduct self-adaptive adjustment according to the current input data quality; and finally, the fine-tuned PID is used for generating an output instruction of the potentiostat, so that the optimal cathode protection effect and the optimal energy consumption efficiency are both considered. Through the mode, the capability of responding to noise interference and sudden abnormal events under on-site complex working conditions is remarkably enhanced, so that a more scientific, reasonable, energy-saving and efficient current control instruction is provided for the output of the potentiostat, and the optimal protection effect and the optimal energy consumption balance are realized.

The invention provides an extracellular vesicle marker separation-free detection method based on nanoparticle enhancement, and belongs to the technical field of detection methods, the method comprises the following steps: preparing gold nanoparticles with the surface modified with a first antibody, the first antibody being used for specific recognition of an extracellular vesicle surface marker; determining the particle size distribution of the gold nanoparticles by adopting a dynamic light scattering method, and determining the surface potentials and surface isoelectric points of the gold nanoparticles by adopting a potentiostat; adopting a transmission electron microscope to characterize the morphology of the screened gold nanoparticles; co-modifying polyethylene glycol molecules on the surfaces of the gold nanoparticles to form an anti-interference layer; mixing the gold nanoparticles with uniform morphology with a sample to be detected; adding a second antibody into the mixed system; distinguishing signals of the binding-state second antibody and the free-state second antibody through fluorescence lifetime analysis; preparing an extracellular vesicle standard substance, and obtaining a standard curve and a system response curve; the optimal detection condition is determined by solving the detection system optimization equation set, and separation-free detection is carried out.

The invention belongs to the technical field of steel plate pickling, and relates to a method for carrying out pretreatment and pickling end point judgment on hot-rolled strip steel in hydrochloric acid. The method specifically comprises the following steps: taking a to-be-used hydrochloric acid liquid for testing, heating the hydrochloric acid liquid, adding a wetting reagent A and a potential stabilizing reagent B, and putting a to-be-measured hot-rolled strip steel into the hydrochloric acid liquid; and measuring the pickling process of the hot-rolled strip steel by adopting a dual-electrode detection system and a constant potential rectifier, synchronously recording electrode potential values in different time periods in the process, and taking a time point when a potential first-order derivative value is basically unchanged as the pickling end point time of the hot-rolled strip steel. According to the method, the implementation process is simple, only certain manpower needs to be input for manual operation, and analysis instruments related to related work are mature; the method can effectively measure the pickling end point of the hot-rolled strip steel, especially the ultra-high-strength hot-rolled steel plate in the acid liquor, eliminates the effects of various influence factors in pickling, and has extremely high practical application value.

The invention relates to an electrochemical analysis method and platform compatible with screen-printed electrodes (SPE) (27) and any potentiostat (2) designed for cell-based tests, enabling cells to maintain healthy proliferation while being shielded from external influences.

The invention provides an electrochemical selective extraction process and device, and relates to the technical field of material extraction in the nuclear fuel circulation process, and the electrochemical selective extraction process comprises the following steps: respectively carrying out corrosion potential tests on an uncontaminated stainless steel sample and a stainless steel sample contaminated with nuclide; obtaining the corrosion potential a of the uncontaminated sample relative to the cathode and the corrosion potential b of the contaminated nuclide sample relative to the cathode; putting a to-be-treated metal workpiece of which the surface is adhered with a pollutant material into an anode basket of an electrochemical extraction device, and connecting the anode basket to an anode of a direct-current power supply or a potentiostat; mixing nitric acid, sodium nitrate, a corrosion inhibitor and a slow release agent to prepare an electrolyte; a cathode basket of the extraction device is connected with a negative electrode of a direct-current power supply or a potentiostat, an anode basket is nested in the cathode basket, and the anode basket and the cathode basket are jointly immersed in electrolyte for extraction. According to the method, pollutants adhering to the irregular metal surface are effectively removed and recycled, the extraction rate of contaminated metal nuclides reaches 99% or above, and the introduction amount of matrix elements is lower than 3500 ppm / g matrix.

The present disclosure presents glucose monitoring systems and methods. One such system comprises a glucose monitoring sensor having at least a counter electrode, a reference electrode, and a working electrode; and a silicon-carbide-silicon-carbide-nanoparticles-electrospun-nanofibrous-membrane contacting the working electrode. The system further includes a glucose oxidase enzyme solution contacting the silicon-carbide-silicon-carbide-nanoparticles-electrospun-nanofibrous-membrane, wherein a conductive polymer membrane assists in binding the glucose oxidase enzyme composition with the silicon-carbide-silicon-carbide-nanoparticles-electrospun-nanofibrous-membrane. Other systems and methods are also provided.

A clinical bedside system facilitates care for complex care patients. The system can include a medical device having a biosensor with an inert substrate and a working electrode, a counter electrode, and a reference electrode deposited thereon. The working electrode can have an antifouling membrane thereover to which a capture antibody is immobilized. The capture antibody can be configured to capture a biomarker between it and a detection antibody, thereby sandwiching the infection biomarker between the antibodies for a detectable redox reaction between an enzyme conjugated to the detection antibody and the working electrode. The counter electrode can complete completes an electrical circuit including the working electrode. The reference electrode can be operably connected to the electrical circuit. The reference electrode can be configured to provide a reference point against which changes in potential at the working electrode can be measured, for example, with a potentiostat.

The present disclosure presents glucose sensing methods and systems. One such system comprises an electrospun-nanofibrous-membrane (ENFM)-based amperometric glucose sensor integrated on a silicon chip, in which the glucose sensor has a working electrode, a reference electrode, and a counter electrode, wherein the working electrode comprises an ENFM-based sensing electrode. The system further comprises a potentiostat circuit integrated on the silicon chip such that the potentiostat circuit comprises a voltage control unit to control a voltage difference between the working electrode and the reference electrode and a transimpedance amplifier to measure a current flow between the working electrode and the counter electrode, in which a strength of the current flow corresponds to an amount of glucose present in a sample of blood on the glucose sensor.

The modular potentiostat comprises an electric control main body and a heat dissipation module which are detachably installed, a normally-closed assembly is arranged at the bottom of the inner side of the electric control main body, and when the heat dissipation module is installed at the bottom of the electric control main body, the top of the heat dissipation module is suitable for opening the normally-closed assembly in a jacking mode; the electric control main body is communicated with the space in the heat dissipation module; and after the heat dissipation module is detached, the normally-closed assembly restores the closed state. The constant potential rectifier is disassembled into two main parts, so that convenience is provided for carrying, mounting and other scenes of the constant potential rectifier; meanwhile, due to the modular design, dust easily permeates into openings of the electric control main body and the heat dissipation module, through the design of the normally-closed assembly, only after the heat dissipation module is installed, the normally-closed assembly in the electric control main body can open space communication from the bottom of the electric control main body to an inner cavity of the heat dissipation module, and therefore dust is prevented from entering the electric control main body when the electric control main body is not used.

The invention relates to the field of photochemistry and electrochemistry. An electrochemical experimental device for spectral measurement comprises a high-voltage direct current power supply, a charging resistor, a charging line, a spark switch, a capacitor, a power distributor, an attenuator, a transmission line I, an oscilloscope, a transmission line II, a bracket, a sample cavity, an optical tester, a thermometer, a semiconductor refrigerator, a heat conduction platform and a constant potentiostat. The sample cavity has a compact structure and balances the requirements of electrochemical experiments and spectral experiments. An electrode with a light reflection function makes the light diffusion path shorter, the light scattering is lower, and the signal-to-noise ratio of the spectrum is improved. The device has a specially designed voltage pulse generating circuit and a compact sample cavity. After the sample is subjected to high voltage treatment, the electrochemical characteristics and spectral characteristics of the sample can be studied at the same time. The high-voltage pulse applied to the sample is regular and stable, and the signal-to-noise ratio of the obtained spectrum is improved. The high-voltage pulse generating circuit is relatively simple, and a high voltage can be applied to the sample to perform spectral and electrochemical measurements.

An electrochemical method for detecting, identifying, and quantifying ions and nutrients dissolved in water through voltammetry, and equipment to carry out the method, including: a preparation / placement stage of a sensor, with a reference electrode, working electrode, and counter electrode, in a potentiostat; a stage for contacting a sample or analysis solution containing the analyte with the sensor; a stage for applying, controlled via software from a computer system, electrical stimulation to the sample through Cyclic Voltammetry, Normal Pulse Voltammetry, Differential Pulse Voltammetry, or Square Wave Voltammetry, with a step potential and pulse amplitude range between −3,000 mV and 3,000 mV; and a stage for characterizing one or more analytes based on at least one measurement of the signals resulting from the oxidation-reduction of the analyte(s).

There is provided a glucose sensor system comprising: a transmitter (2) for containing a battery (212), the transmitter being for placement on top of patient skin; a transcutaneous connector (3) comprising at least one conductive path; and an implantable monolithic integrated circuit (I) for placement beneath the patient skin, wherein the implantable monolithic integrated circuit comprises a potentiostat and an electrochemical sensing element; wherein the potentiostat is electrically coupled to the transmitter (2) via the transcutaneous connector (3), and the electrochemical sensing element is configured to sense glucose concentration and generate an electrical signal representative of the glucose concentration, and wherein the potentiostat is electrically connected to the electrochemical sensing element.

The invention belongs to the technical field of water environment detection, and particularly relates to a portable detection device and method for the total discharge amount of water pollutants. The portable detection device at least comprises a three-electrode sensor module, a potentiostat module, an analog-to-digital conversion module, a microcontroller, a peripheral circuit of the microcontroller, a Bluetooth module and a power module, and the three-electrode sensor module comprises a working electrode coated with a tungsten oxide film, a reference electrode and a counter electrode; the constant potential rectifier comprises at least two electrode channels, is connected with the microcontroller and the analog-to-digital conversion module and is used for controlling voltage to detect hydrology and water quality parameters; and the Bluetooth module is used for being paired with intelligent equipment to transmit data. The portable water environment detection device and the hydrology and water quality synchronous detection method can be provided, the problem that scattered and small drain outlets cannot be detected is effectively solved, and the detection device is provided for real-time online evaluation of the total discharge amount of water pollutants.

The disclosure discloses a method for enhancing denitrification of sewage with a low carbon-to-nitrogen ratio by using an electrode biocarrier, and relates to the field of sewage treatment. The disclosure uses a conductive material as a microbial carrier and a potentiostat to induce a micro-electric field for directional acclimation and enrichment of electroactive denitrification microorganisms, and realizes a high-efficiency denitrification of the sewage with a low carbon-to-nitrogen ratio. The disclosure aims to provide a technical method for solving the problem of deep denitrification of municipal sewage with a low carbon-to-nitrogen ratio.

This invention relates to a temperature-controlled stress electrochemical metal hydrogen permeation testing device and method. The testing device includes a hydrogen permeation electrolytic cell, a hydrogen efflux electrolytic cell, a first temperature control mechanism, a second temperature control mechanism, a tensile testing machine, a potentiostat, an auxiliary electrode, a reference electrode, and a working electrode. The hydrogen permeation electrolytic cell is equipped with a first temperature control mechanism for controlling the temperature of the hydrogen permeation electrolytic cell, and the hydrogen efflux electrolytic cell is equipped with a second temperature control mechanism for controlling the temperature of the hydrogen efflux electrolytic cell. The sidewalls of the hydrogen permeation electrolytic cell and the hydrogen efflux electrolytic cell are respectively provided with a first connecting pipe and a second connecting pipe. Both the hydrogen permeation electrolytic cell and the hydrogen efflux electrolytic cell are equipped with an auxiliary electrode and a reference electrode. The two ends of the working electrode are respectively connected to the tensile testing machine. The working electrode, the reference electrode, and the auxiliary electrode are respectively connected to the potentiostat. A sample is welded onto the working electrode. The hydrogen-filled surface and the hydrogen-effluxed surface of the sample are sealed to the first connecting pipe and the second connecting pipe through sealing gaskets.

A method for detecting hazardous materials using an electro chemical sensor system by electrospinning a polymer solution to produce a dissolvable nanofiber mesh and collecting contaminant particles on the nanofiber mesh by exposing the nanofiber mesh to an aerosol containing contaminant particles. The electro chemical sensor system comprises an electrochemical cell connected to a potentiostat. The electrochemical cell comprises a working electrode comprised of a nanofiber membrane and a reference electrode.

The present invention discloses a buried pipeline stray current anode transient interference corrosion monitoring device and a testing method, relating to the technical field of stray current interference corrosion monitoring. The device comprises an experimental box, an experimental medium, a transient interference system and an interference testing system. The transient interference system comprises a constant potential instrument, a switching controller, a metal electrode bundle, an auxiliary electrode group and a reference electrode. The output value and output cycle of the constant potential instrument are adjusted to simulate the interference intensity and interference frequency of cathodic protection and stray current. The buried pipeline stray current anode transient interference corrosion monitoring device and the testing method of the present invention utilize a metal electrode bundle to realize the monitoring and evaluation function of the transient corrosion effect of the anode transient interference on the pipeline. The current distribution on the surface of each metal electrode is scanned by program control to characterize the local corrosion characteristics of the pipeline. The method is more comprehensive and systematic than traditional testing methods, and the data obtained is more valuable for reference.

The utility model relates to the technical field of storage tank and cathode protection combined current shunting adjustment balance, and discloses a device for realizing storage tank and cathode protection combined current shunting adjustment balance, which comprises a box body, a sliding door arranged on the front side of the box body, and a built-in working plate arranged in an inner cavity of the box body, the built-in working plate comprises a slide-wire rheostat, a wire leading to a shell display meter, a safety assembly, a power line, a cable leading to the potentiostat device and a cathode cable led into the protected storage tank, a grounding assembly is arranged at the bottom of the box body, and a cabinet lock is arranged on the sliding door. According to the utility model, by adjusting the resistance of each loop, each protected storage tank obtains enough balanced current which does not exceed the standard, so that each storage tank in a combined cathode protection system can be fully and effectively protected; and meanwhile, necessary accessories are additionally arranged, and the overall dimension and the like are designed, so that the whole device becomes equipment capable of realizing standardized production, and is relatively practical and suitable for being widely popularized and used.

The invention belongs to the field of bridge cable maintenance, and discloses an anti-corrosion maintenance method and an anti-corrosion maintenance structure for cable sheath damage and cable high-strength steel wires, which are used for solving the problems of complete sealing and corrosion prevention in the cable sheath repair process and the durability of the repaired cable. A damaged part of a cable sheath is firstly coated with a waterproof insulating coating material, then the damaged part of the sheath is filled with a solid electrolyte sealing material, and the measuring ends of an auxiliary anode and a reference electrode are arranged in the solid electrolyte sealing material; the auxiliary anode is connected with an electronic variable resistor, an automatic control rectifier or a constant potential rectifier, and a conductive loop is formed between the auxiliary anode and a cathode access point on a cable high-strength steel wire; and wrapping the damaged part of the cable by using a physical anti-corrosion layer to form a closed anti-corrosion system at the damaged part of the sheath. According to the corrosion-resistant maintenance method for cable sheath damage and cable high-strength steel wires, the local damage position of the sheath can be maintained, inhibition of corrosion of the cable steel wires at the damage position of the sheath is enhanced, the influence of electrochemical corrosion on the service life of the cable is relieved, and therefore the service life of the cable is greatly prolonged.

The invention discloses a current control method for a potentiostat of an integrated impressed current cathodic protection system, and the method comprises the steps: controlling each auxiliary anode to output different current values in sequence in a time-sharing manner, and measuring the potential value of each reference electrode; calculating a mathematical coupling function of the auxiliary anode current and the reference potential variation through polynomial fitting; establishing a mathematical model between the potential of each reference electrode and the current of the auxiliary anode, and calculating a predicted potential value of the reference electrode; solving the current of each auxiliary anode by using a particle swarm optimization algorithm according to the predicted potential value of the reference electrode and the target optimization function; solving the proportion of the current of each auxiliary anode relative to the total protection current; the constant potential rectifier automatically distributes current to each auxiliary anode according to the proportion relation; the invention further discloses a corresponding control system. The integrated impressed current cathodic protection system can adjust the optimal protection strategy in real time in different marine environments; the effects of uniform potential distribution of the ship body and small protection current are achieved.

The invention provides a detachable screw protection device for a screw hoist. The detachable screw protection device comprises a small potentiostat and a protection assembly, the protection assembly is arranged at the top of the screw hoist and comprises a protection cover, a fixed anode and a cathode electric brush, the fixed anode and the cathode electric brush are both arranged outside a screw and matched with each other to form cathode protection on the screw, the fixed anode is connected with an anode of the small potentiostat through a cable, and the cathode electric brush is connected with the cathode of the small potentiostat through a cable. And the cathode brush is connected with the cathode of the small-sized potentiostat. By arranging the insulating sleeve, the protective cover, the cathode electric brush, the fixed anode, the small-sized potentiostat and other components, the protective cover can simply protect the screw rod, and meanwhile, the cathode electric brush, the fixed anode and the small-sized potentiostat are matched with one another to form cathode protection current to protect the screw rod.

Provided are systems, cartridges, devices and methods for detecting a target analyte in a test sample. The system employs a multitude of magnetic sources for moving magnetic beads in a sequential movement through various portions of e.g. a cartridge or strip, such as from one or more hybridization portions, through one or more washing portions, and to a redox portion. The system employs an electrode set and a potentiostat for performing amperometry to obtain an electrochemical measurement based on conversion of a redox active molecule. Also provided are methods for detecting a target analyte using the systems, and cartridges and strips for use in the system or a device of the system.

The invention relates to a connection element (1) for a potentiostat (2) for establishing an electrically conductive connection between an electrode (3) with a threaded hollow screw (5) and the potentiostat (2), wherein the connection element (1) comprises a housing (6) and a circuit board (7) arranged within the housing (6), the circuit board (7) being connectable to the potentiostat (2) via electrical conductors (8), a connector (9) for establishing a first electrical contact between the electrode (3) and the circuit board (7) by inserting the connector (9) into the hollow screw (5) is arranged in the center (Z) of the circuit board (7), at least one spring contact pin (10) for establishing at least one further electrical contact between the electrode (3) and the circuit board (7) by inserting the connector (9) into the hollow screw (5) is arranged on the circuit board (7), and the housing (6) is a spring element (11) features, which is designed toWhen the connector (9) is inserted into the hollow screw (5), it engages in the thread (4) and creates a positive connection. In this way, a connection element is provided for connecting a conventional electrode to a potentiostat, enabling quick and secure electrode mounting.

The application discloses a digital constant potentiostat based on linearity calibration technology, comprising a quantizer, a control logic module, a current domain digital-to-analog converter, an oscillator and a frequency mixer, which constitutes a digital closed loop circuit with an electrochemical sensor, and realizes constant potential difference between a working electrode and a reference electrode of the electrochemical sensor and sensing current size detection between the working electrode and a counter electrode through negative feedback regulation of the digital closed loop circuit, so that a greater sensing current detection dynamic range is realized under extremely low power consumption, the differential current domain digital-to-analog converter is used to quantitatively transmit the linearity characteristics of the sensing current in the form of frequency while converting the sensing current into a digital code word, so as to realize linearity calibration of the mapping relationship between the detected sensing current size and the output digital control code word, thereby realizing high linearity sensing current detection under extremely low power consumption.