66 results about "Recording electrode" patented technology

The invention discloses a closed-loop deep brain regulation and control system for epilepsy treatment, and the system comprises an electroencephalogram signal collection module which collects neural electrophysiological signals in real time by implanting a recording electrode in a cerebral cortex or hippocampal brain area; the electroencephalogram signal real-time analysis module is used for outputting the epileptic seizure period prediction probability xi through a seven-layer full-connection neural network based on the 33-dimensional feature vector so as to realize epileptic seizure early warning; when the zeta is greater than or equal to a threshold value, the electrical stimulation regulation and control module is used for triggering electrical stimulation, filtering out a frequency band required to be regulated and controlled according to filtering, calculating and predicting electrical stimulation intensity and then correcting and outputting pulse stimulation, so that personalized electrical stimulation regulation and control are carried out on a specific frequency band, and detection is continuously carried out until the frequency band becomes normal; and the medicine intervention module is used for triggering a micro-injection pump to carry out medicine infusion through a pulse signal. According to the system, epilepsy treatment is improved from empirical parameter adjustment to accurate regulation and control based on real-time nerve physiological signals, and a safer and more effective treatment choice is provided for a drug-refractory epilepsy patient.

Police officers use conducted electrical weapons (“CEWs”) and cameras. A camera and a CEW may cooperate to improve the performance and use of the CEW and evidence collection by the camera. A camera and a CEW may also cooperate to improve the safety of the user and the target. Improvements may include improving targeting of the CEW, identifying and classifying body parts of the target as suitable or unsuitable for electrode deployment, adjusting electrode trajectory prior to launch, and automating electrode launch. Evidence collection may be improved by recording placement of electrodes on the target. Safety of the target may be improved by monitoring the movements of the target and altering characteristics of the delivered stimulus signal if potential harm to the target may occur.

The invention provides an underground engineering leakage three-dimensional detection method, which comprises the following steps of: arranging a three-dimensional electrode system on an outer side and an inner side drill hole of a to-be-detected underground enclosure structure, and detecting and recording potential data and space coordinates of an electrode array; repeatedly collecting and preprocessing the collected potential data to eliminate the influence of current intensity difference and stratum conductivity difference; based on the physical coupling relationship between the electric field intensity and the formation resistivity, filling the data blind area of the inter-hole area; the three-dimensional space model of the electric field intensity is optimized and fitted through an intelligent algorithm, a three-dimensional equal-straight-plane image of the electric field is generated after data reliability is verified, and space coordinates of an electric field abnormal area are marked as suspected leakage points. The problems that in an existing detection method, positioning is not accurate, and the applicability is limited are solved.

The invention provides a device and system implanted outside epidural under ultrasonic guidance for temporary electrode stimulation of spinal cord, and the device comprises a risk assessment module which carries out the comprehensive assessment of a patient through a multi-modal risk assessment model, and outputs a risk level or probability; the configuration selection module is used for analyzing the parameter information of the patient according to the parameter information of the patient when the evaluation result is passed, and setting guide configuration requirements; the probe guiding module guides the temporary electrode through an ultrasonic thermodynamic diagram; the effect test module is used for testing electrode functions by using a stimulator and adjusting electrode positions; the fixing and closing module fixes the electrode to avoid displacement; and the recording and monitoring module is used for recording electrode implantation depth, stimulation parameters and patient response. The system can reduce invasiveness and ultrasonic guidance accurate positioning, reduces errors and complications, is easy to popularize and apply, is relatively simple to operate, and is suitable for being popularized and applied in more medical places.

The invention discloses a closed-loop electrical stimulation regulation and control system based on a tissue state, and relates to the field of medical apparatuses and instruments. The system comprises a recording electrode, an amplifier, a neural signal acquisition system, a pulse stimulator and a stimulating electrode. The nerve electrophysiological signals are recorded and analyzed in real time through the nerve electrode, the power of the regeneration sensitive or pain sensitive frequency band representing the tissue regeneration or pain state is extracted from the nerve electrophysiological signals, and electrical stimulation is carried out according to the power of the regeneration sensitive or pain sensitive frequency band for regulation and control, so that organ regeneration is promoted, organ functions are recovered, or pain response is inhibited, and the tissue regeneration or pain treatment effect is improved. Damage to tissues caused by electrical stimulation is reduced, and the safety of electrical stimulation is improved.

The present disclosure is directed to neural interface devices and methods that accesses the subarachnoid space to enable minimally invasive modulation and recording of neural structures. Exemplary embodiments may comprise an implantable pulse generator and a microelectrode catheter. In particular embodiments, the microelectrode catheter comprises one or more stimulating and recording electrodes. Exemplary embodiments may also include methods comprising performing a lumbar puncture to access the spinal subarachnoid space and advancing microcatheter through the spinal subarachnoid space.

A neural stimulus comprises at least three stimulus components, each comprising at least one of a temporal stimulus phase and a spatial stimulus pole. A first stimulus component delivers a first charge which is unequal to a third charge delivered by a third stimulus component, and the first charge and third charge are selected so as to give rise to reduced artefact at recording electrodes. In turn this may be exploited to independently control a correlation delay of a vector detector and an artefact vector to be non-parallel or orthogonal.

The subject matter of the present invention is "System and method for visualizing electrophysiological data." The present invention discloses a method and system for visualizing electrophysiological information sensed by electrodes on a catheter, the method and system comprising recording the time of electrode signal acquisitions, calibrating a reference electrode signal acquisition, specifying a relative time of each recorded time of an electrode signal acquisition relative to the reference electrode signal acquisition, identifying the electrodes having signal acquisitions, associating the specified relative times with the identified electrodes to generate an electrode signal acquisition sequence, and generating a visual representation of the electrode signal acquisition sequence using a graphical image of the electrodes, wherein individual electrodes are visually labeled to represent the electrode signal acquisition sequence.

The present invention discloses an esophageal PH-electromyographic combined electrode catheter, comprising a tube body, a PH wire and a diaphragm wire, wherein the surface of the tube body is provided with two PH electrodes, a plurality of diaphragm electrical signal recording electrodes and a diaphragm electrical signal reference electrode; the two PH electrodes are respectively at the end and the middle of the tube body, the plurality of diaphragm electrical signal recording electrodes are all located between the two PH electrodes, and the diaphragm electrical signal reference electrode is located at the proximal end of the PH electrode in the middle; all the PH electrodes are connected to the PH wire in the tube body, and the signal output end of the PH wire is provided with a PH processor connector; the diaphragm electrical signal reference electrode and all the diaphragm electrical signal recording electrodes are connected to the diaphragm wire in the tube body, and the signal output end of the diaphragm wire is provided with an amplifier connector. The present invention can not only improve the accuracy of catheter positioning and simplify operation, but also reduce the patient's discomfort, and can also detect diaphragm function and help discover the cause of gastroesophageal reflux.

The nerve monitoring device comprises an interface box, a monitor and a tested body, the interface box is connected with the monitor, the interface box is connected with a recording electrode, a grounding subcutaneous needle, a stimulation loop subcutaneous needle and a stimulation probe, a trachea cannula is arranged on the recording electrode, and the stimulation probe is arranged on the grounding subcutaneous needle. The recording electrode, the grounding subcutaneous needle, the stimulation loop subcutaneous needle and the stimulation probe are all arranged on a tested body. According to the nerve monitoring device with the telescopic electrode, nerve walking can be effectively positioned and recognized, nerve point physiological function feedback can be provided in real time in an operation, potential risk or high-risk operation of nerve injury can be warned in advance, the safety and thoroughness of the operation are improved, the nerve monitoring electrode can be stretched out and drawn back, the nerve monitoring device is suitable for patients of different body types, and the operation efficiency is improved. In addition, the electrode probe can be retracted for protection, infection is not prone to being caused, and nerve monitoring data can be conveniently collected, transmitted, processed, analyzed and stored.

A neural stimulation and recording electrode assembly includes a selectively deformable guide tube. The guide tube includes a plurality of sequentially coupled connecting structures, wherein each connecting structure of the plurality of connecting structures has a respective central axis, and wherein at least one of the plurality of connecting structures is selectively deformable relative to the central axis of a sequential connecting structure of the plurality of connecting structures such that the central axis of the selectively deformable connecting structure is angularly oriented relative to the central axis of the sequential connecting structure. The electrode assembly further includes an electrode subassembly having a central axis and a plurality of electrode contacts that are configured for selective radial movement about and between a retracted position and a deployed position, wherein in the deployed position, and relative to the central axis, each electrode contact is spaced radially outwardly from the retracted position.

A neurostimulation system includes a plurality of stimulation electrodes, a plurality of recording electrodes, a waveform generator in electrical communication with the plurality of stimulation electrodes, and one or more computing devices in electrical communication with the plurality of recording electrodes and the waveform generator. The one or more computing devices cause the waveform generator to electrically excite the plurality of stimulation electrodes of the plurality of stimulation electrodes. After electrically exciting the stimulation electrodes, a neural signal is received from the plurality of recording electrodes. The neural signal is determined to be an electrically evoked compound action potential (“ECAP”) by determining one or more features of the neural signal. One or more stimulation parameters are determined based on one or more characteristics of the ECAP. The waveform generator is then caused to electrically excite the plurality of stimulation electrodes according to the one or more stimulation parameters.

An electrocorticographic interface device includes a flexible thin-film electrode array formed on a biocompatible substrate such as polyimide, the electrode array having a plurality of recording electrodes and interconnect lines patterned on the biocompatible substrate, and the flexible thin-film electrode array further includes an array of perfusion holes distributed across the biocompatible substrate.

The invention relates to the technical field of process regulation and control, and particularly discloses a method and equipment for detecting and controlling the residual length of an electrode in a nano powder preparation process. The method comprises the following steps: recording the average voltage U of an electric arc within a period of time t when an electrode is at different heights H, and obtaining the average electric field intensity EH of the electric arc corresponding to the different heights H; a relational expression between the distance h between the electrode sheath gas outlet and the molten pool and the electrode sheath gas pressure P is simulated; the arc voltage U'and the electrode sheath gas pressure P of the electrode at a certain height H are recorded, so that the arc length Larc is calculated, and h can be calculated by substituting the electrode sheath gas pressure P into a formula; and deducting the arc length Larc from the distance h between the electrode sheath gas outlet and the molten pool to obtain the electrode length Lel. According to the invention, the system is provided with instruments, so that the material depth and the electrode length can be continuously monitored on line in a non-stop state.

This disclosure relates to medical implant systems and apparatuses capable of treating a seizure condition through the use of recording and stimulating electrodes. The apparatus includes an internal pulse generator in communication with a wireless communication module; one or more recording electrodes in communication with the internal pulse generator, wherein the one or more recording electrodes are configured to monitor to detect one or more field potentials produced by neural tissue in proximity to the one or more recording electrodes; one or more stimulating electrodes in communication with the internal pulse generator, wherein the one or more stimulating electrodes are configured to stimulate the vagus nerve.

The application relates to the technical field of clinical medicine, and particularly discloses a lower limb nerve detection method and device in artificial total hip arthroplasty. The method comprises the following steps: acquiring performance state data of a lower limb nerve detection device, monitoring intraoperative environment data of artificial total hip arthroplasty, comprehensively analyzing to obtain a nerve detection accuracy evaluation value; recording electrode pair waveform data, comprehensively analyzing to obtain an electrode pair waveform abnormality evaluation value; correcting a parameter according to the waveform abnormality evaluation to obtain a waveform abnormality evaluation threshold value, and performing abnormality feedback. The application provides a lower limb nerve detection method and device in artificial total hip arthroplasty, which can help doctors to identify the existence and degree of nerve injury, help to distinguish different types of nerve injury, and thus formulate a targeted treatment scheme, can accurately locate the nerve injury, and can also monitor the recovery progress of the nerve function, help to timely adjust the treatment scheme, and improve the treatment effect.

The application relates to the technical field of physiological and pharmacological experimental devices, and discloses a muscle spindle discharge activity experimental recording device based on a nerve-muscle specimen, which comprises an experimental box, a tension sensor is fixedly connected to the left side of the experimental box, an electric sliding rail is fixedly connected to the right side of the experimental box, a wire clamp is arranged in the electric sliding rail, a movable adjusting mechanism is arranged at the back of the experimental box, an auxiliary placing mechanism is arranged in the experimental box, an adjusting and mounting mechanism is arranged at the bottom of the experimental box, in the using process, the sliding plate is moved, the spring is matched, the position of the connecting frame is adjusted, the left and right positions of the recording electrode clamp are adjusted, the first threaded rod is rotated, the first limiting rod is matched, the height and the front and back positions of the recording electrode clamp are adjusted, the motor works, the height of the silica gel support table is adjusted, the worm is rotated, the position of the mounting frame is adjusted, and the mounting between different mounting tables and mounting equipment is satisfied.

Stimulation and recording electrode assemblies that are particularly useful for Automatic Period Stimulation (APS). Such embodiments are compatible with nerve monitoring systems to provide continuous stimulation of a nerve during surgery. Certain embodiments include an electrode assembly having cuff including a body and two ears extending from the body. Within the body, at least one electrode is supported and connected to a lead wire assembly. The ears can be brought together to enlarge a gap in the body so that the electrode assembly can be fixated around a nerve. Other embodiments include an electrode assembly including first and second needle electrodes that each have a tip. A body is provided to interconnect the needle electrodes and can be manipulated to move the tips either toward or away from one another. Disclosed embodiments provide nerve monitoring and stimulation in cases where the nerve is only partially dissected.

The present invention discloses a real-time ultrasonic stimulation electric signal recording chip and a preparation method thereof, where the preparation method includes the following steps: S1 manufacturing an interdigital electrode on a piezoelectric substrate to obtain a surface acoustic wave chip, and manufacturing a recording electrode and an electrode lead; S2, manufacturing an insulation protection layer on the chip obtained in the S1, and processing the insulation protection layer to form the recording electrode, so as to obtain a chip combining the interdigital electrode and the recording electrode; S3, preparing a PDMS cavity; and S4, bonding the PDMS cavity prepared in the S3 and the chip obtained in the S2. In the present invention, combining the interdigital electrode generating a surface acoustic wave ultrasound with a multi-channel recording electrode, such that real-time recording of a multi-channel electric signal under ultrasonic stimulation is achieved.

A method may include obtaining first and second time series (TS1), (TS2) of stimulation data, and a first and second time series of control data. TS1, TS2 may provide a plurality of pairs of data points such that each of the plurality of pairs include corresponding data points from both TS1 and TS2. The obtained time series may be analyzed by applying an algorithm (Alg) to TS1 and TS2 of stimulation data to create an algorithm value corresponding to each of the plurality of pairs of data points. Alg=(|TS1|+|TS2|) / 2−|TS1−TS2|. Positive algorithm values for a predetermined period of time (AlgVarTime) may be summed to create a signal. Peak(s) in the signal may be determined, and a conduction velocity may be determined using a latency and a distance between a stimulus electrode and a recording electrode.

Determining the force exerted by a catheter when it is inserted into tissue. [Solution] A method for performing a medical procedure is provided, which involves providing a probe having a known spring constant for insertion into a patient, wherein the probe has electrodes and position sensors at each location along the probe, and recording the relative position coordinates of the electrodes and position sensors when the probe is in an unrestrained state. While the probe is in the patient and deformed by contact with the patient's tissue, changes in the relative position coordinates of the electrodes and position sensors in contact with the tissue are recorded, and the shape of the deformed probe is calculated in response to the recorded changes. In response to the known spring constant and the calculated probe shape, the respective forces exerted by the tissue on each electrode are calculated, and the electrical signals from the tissue through the electrodes are controlled in response to the calculated forces on the electrodes.

The invention relates to the technical field of culture, and discloses an in-vitro cell culture electrical stimulation and recording device which comprises four quarter frames, the four quarter frames are mutually combined to form an integral frame, and a connection adjusting assembly capable of adjusting the distance between every two quarter frames is arranged between every two quarter frames. The recording electrode array comprises a 1 / 4 frame, the side surfaces of the two sides of the 1 / 4 frame are each provided with a first inlaying groove, a stimulating electrode is detachably inlaid in each first inlaying groove, and a first fixing assembly used for fixing the stimulating electrode is arranged in each first inlaying groove. A standard plug-in type experiment unit is formed, a user only needs to put the whole device into a standard culture dish, complex electrode arrangement can be completed, and the experiment preparation process is greatly simplified.

Systems and methods for calculating patient information are provided herein. The method includes determining a transfer matrix, recording potentials via a first set of recording electrodes located at a first set of recording locations to create a first set of recording signals, and calculating patient information for a set of target locations by applying the transfer matrix to the first set of recording signals. The transfer matrix is a feature of an electrical characteristic of tissue between the first set of recording locations and a set of target locations.

Abnormal activity in the brain can be detected by identifying changes in tissue excitability measured in response to stimulation of fiber tracts such as the corpus callosum. A stimulating electrode contact can apply a stimulation to the fiber tract, which can have one or more terminals to a cortex of a patient's brain, and a recording electrode contact positioned in the fiber tract and / or the cortex to record a tissue excitability response to the stimulation. A controller can receive the tissue excitability response from the at least one recording electrode, identify a parameter of the tissue excitability response, and predict the abnormal activity in the patient's brain based on the parameter being different from a baseline for the parameter. When an abnormal activity is predicted the patient can be alerted to start a therapy and / or a therapy can be applied in closed loop manner by a connected therapy device.

The application relates to the technical field of process regulation, and particularly discloses a method and equipment for detecting and controlling the residual length of an electrode in a nanometer powder preparation process. In the method, the average arc voltage U of an electrode in a period t is recorded when the electrode is at different heights H, the average arc electric field intensity E corresponding to the different heights H is obtained H ; a relationship between the distance h of an electrode sheath gas outlet from a molten pool and the electrode sheath gas pressure P is simulated; the arc voltage U' and the electrode sheath gas pressure P of the electrode at a certain height H are recorded, so that the arc length L arc is calculated; the electrode sheath gas pressure P is substituted into the formula to calculate h; and the distance h of the electrode sheath gas outlet from the molten pool is deducted by the arc length L arc , so that the electrode length L ele is obtained. The application realizes uninterrupted online monitoring of material depth and electrode length under a non-stop state through a system instrument.

In one embodiment, the invention relates to systems, methods, and apparatus relating to the detection of a neuropathy such as a periopertive neuropathy. In one embodiment, a wristband comprising a plurality of anodes and cathodes is used. The wristband can be a component in a electrode array that includes a plurality of reference or recording electrodes. The electrode array can be configured to stimulate and collect responsive signals from an ulnar, a median, radial and posterior tibial nerve. The simulation and signal collection can be performed on a continuous basis for time periods of interest such as a given perioperative time period using a monitoring device.

The invention discloses a flexible electrode array for recording electroencephalogram signals. The flexible electrode array comprises a basic appearance structure and a metal wire layer. The basic outline structure comprises an upper packaging layer and a lower substrate layer. The metal wire layer is arranged between the upper packaging layer and the lower substrate layer, the metal wire layer comprises an array area, a strain release interconnection area and a connection area, one end of the strain release interconnection area is connected with the array area, the other end of the strain release interconnection area is connected with the connection area, the array area comprises a plurality of independent recording electrodes, each recording electrode is in a disc shape, and the recording electrodes are arranged in the array area. The wire of the strain release interconnection area is of a convolute geometric structure, and the connection area comprises at least one bonding pad. Wherein the recording electrode and the metal surface of the bonding pad are exposed out of the upper packaging layer through the windowing part. The high-quality electroencephalogram signals are obtained through arrangement of the disc-shaped recording electrodes and the multi-channel array electrodes, and the stability of the signals in long-term use is guaranteed by means of the strain release interconnection area in the convolute geometry shape.

Methods and systems for providing deep brain stimulation (DBS) for a patient are described. Evoked potentials (EPs) evoked by the stimulation are recorded and compared to modeled EPs. The modeled EPs are determined based on an overlap of stimulation field models (SFMs) for a given set of stimulation parameters with a target volume of the patient's brain, the target region being the source of the EPs. The target volume may include the patient's subthalamic nucleus (STN), for example. The modeled EPs are used to predict electrical signals that will be sensed at recording electrodes of an electrode lead. The recorded EPs can be compared to the modeled electrical signals to guide aspects of the stimulation therapy.

Obesity and other medical conditions can be managed using a closed-loop system, which uses one or more implantable recording electrodes, a processing device, and one or more implantable stimulating electrodes. The one or more implantable recording electrodes can record signals from a portion of one or more subdiaphragmatic branches of a patient's vagus nerve. The processing device can be configured to: receive the signals from the portion of the one or more subdiaphragmatic branches of the patient's vagus nerve, perform signal processing to decode the signals from the portion of the one or more subdiaphragmatic branches of the patient's vagus nerve, and configure a stimulation to decrease the patient's hunger and / or increase the patient's satiety based on the decoded signals. The one or more implantable stimulating electrodes can deliver the configured stimulation to another portion of one or more subdiaphragmatic branches of the patient's vagus nerve.

The invention provides two quantitative experiment research methods for influence of semiconductor laser on functional activity of a neural stem. The invention discloses a quantitative experiment research method for influence of semiconductor laser on functional activity of a nerve stem. The quantitative experiment research method sequentially comprises the following steps: (1) connection of a nerve stem specimen and an instrument: putting an in-vitro nerve stem into a multi-electrode nerve specimen box, wherein the adopted multi-electrode nerve specimen box comprises a pair of stimulating electrodes, a grounding electrode and two pairs of recording electrodes; (2) electrically stimulating the nerve trunk; (3) irradiating the nerve stem with laser: irradiating the local section of the nerve stem on the bearing platform by using a semiconductor laser source, and recording the irradiation time length, wavelength and irradiation intensity of the semiconductor laser; (4) electrically stimulating the nerve trunk again; and (5) data processing. According to the invention, the influence result of laser irradiation on the action potential waveform amplitude and conduction velocity of the neural stem can be quantitatively revealed.