24 results about "Recording electrode" patented technology

The invention provides an underground engineering leakage three-dimensional detection method, which comprises the following steps of: arranging a three-dimensional electrode system on an outer side and an inner side drill hole of a to-be-detected underground enclosure structure, and detecting and recording potential data and space coordinates of an electrode array; repeatedly collecting and preprocessing the collected potential data to eliminate the influence of current intensity difference and stratum conductivity difference; based on the physical coupling relationship between the electric field intensity and the formation resistivity, filling the data blind area of the inter-hole area; the three-dimensional space model of the electric field intensity is optimized and fitted through an intelligent algorithm, a three-dimensional equal-straight-plane image of the electric field is generated after data reliability is verified, and space coordinates of an electric field abnormal area are marked as suspected leakage points. The problems that in an existing detection method, positioning is not accurate, and the applicability is limited are solved.

The present disclosure is directed to neural interface devices and methods that accesses the subarachnoid space to enable minimally invasive modulation and recording of neural structures. Exemplary embodiments may comprise an implantable pulse generator and a microelectrode catheter. In particular embodiments, the microelectrode catheter comprises one or more stimulating and recording electrodes. Exemplary embodiments may also include methods comprising performing a lumbar puncture to access the spinal subarachnoid space and advancing microcatheter through the spinal subarachnoid space.

The application relates to the technical field of physiological and pharmacological experimental devices, and discloses a muscle spindle discharge activity experimental recording device based on a nerve-muscle specimen, which comprises an experimental box, a tension sensor is fixedly connected to the left side of the experimental box, an electric sliding rail is fixedly connected to the right side of the experimental box, a wire clamp is arranged in the electric sliding rail, a movable adjusting mechanism is arranged at the back of the experimental box, an auxiliary placing mechanism is arranged in the experimental box, an adjusting and mounting mechanism is arranged at the bottom of the experimental box, in the using process, the sliding plate is moved, the spring is matched, the position of the connecting frame is adjusted, the left and right positions of the recording electrode clamp are adjusted, the first threaded rod is rotated, the first limiting rod is matched, the height and the front and back positions of the recording electrode clamp are adjusted, the motor works, the height of the silica gel support table is adjusted, the worm is rotated, the position of the mounting frame is adjusted, and the mounting between different mounting tables and mounting equipment is satisfied.

Determining the force exerted by a catheter when it is inserted into tissue. [Solution] A method for performing a medical procedure is provided, which involves providing a probe having a known spring constant for insertion into a patient, wherein the probe has electrodes and position sensors at each location along the probe, and recording the relative position coordinates of the electrodes and position sensors when the probe is in an unrestrained state. While the probe is in the patient and deformed by contact with the patient's tissue, changes in the relative position coordinates of the electrodes and position sensors in contact with the tissue are recorded, and the shape of the deformed probe is calculated in response to the recorded changes. In response to the known spring constant and the calculated probe shape, the respective forces exerted by the tissue on each electrode are calculated, and the electrical signals from the tissue through the electrodes are controlled in response to the calculated forces on the electrodes.

The invention relates to the technical field of culture, and discloses an in-vitro cell culture electrical stimulation and recording device which comprises four quarter frames, the four quarter frames are mutually combined to form an integral frame, and a connection adjusting assembly capable of adjusting the distance between every two quarter frames is arranged between every two quarter frames. The recording electrode array comprises a 1 / 4 frame, the side surfaces of the two sides of the 1 / 4 frame are each provided with a first inlaying groove, a stimulating electrode is detachably inlaid in each first inlaying groove, and a first fixing assembly used for fixing the stimulating electrode is arranged in each first inlaying groove. A standard plug-in type experiment unit is formed, a user only needs to put the whole device into a standard culture dish, complex electrode arrangement can be completed, and the experiment preparation process is greatly simplified.

Abnormal activity in the brain can be detected by identifying changes in tissue excitability measured in response to stimulation of fiber tracts such as the corpus callosum. A stimulating electrode contact can apply a stimulation to the fiber tract, which can have one or more terminals to a cortex of a patient's brain, and a recording electrode contact positioned in the fiber tract and / or the cortex to record a tissue excitability response to the stimulation. A controller can receive the tissue excitability response from the at least one recording electrode, identify a parameter of the tissue excitability response, and predict the abnormal activity in the patient's brain based on the parameter being different from a baseline for the parameter. When an abnormal activity is predicted the patient can be alerted to start a therapy and / or a therapy can be applied in closed loop manner by a connected therapy device.

The invention discloses a flexible electrode array for recording electroencephalogram signals. The flexible electrode array comprises a basic appearance structure and a metal wire layer. The basic outline structure comprises an upper packaging layer and a lower substrate layer. The metal wire layer is arranged between the upper packaging layer and the lower substrate layer, the metal wire layer comprises an array area, a strain release interconnection area and a connection area, one end of the strain release interconnection area is connected with the array area, the other end of the strain release interconnection area is connected with the connection area, the array area comprises a plurality of independent recording electrodes, each recording electrode is in a disc shape, and the recording electrodes are arranged in the array area. The wire of the strain release interconnection area is of a convolute geometric structure, and the connection area comprises at least one bonding pad. Wherein the recording electrode and the metal surface of the bonding pad are exposed out of the upper packaging layer through the windowing part. The high-quality electroencephalogram signals are obtained through arrangement of the disc-shaped recording electrodes and the multi-channel array electrodes, and the stability of the signals in long-term use is guaranteed by means of the strain release interconnection area in the convolute geometry shape.

Obesity and other medical conditions can be managed using a closed-loop system, which uses one or more implantable recording electrodes, a processing device, and one or more implantable stimulating electrodes. The one or more implantable recording electrodes can record signals from a portion of one or more subdiaphragmatic branches of a patient's vagus nerve. The processing device can be configured to: receive the signals from the portion of the one or more subdiaphragmatic branches of the patient's vagus nerve, perform signal processing to decode the signals from the portion of the one or more subdiaphragmatic branches of the patient's vagus nerve, and configure a stimulation to decrease the patient's hunger and / or increase the patient's satiety based on the decoded signals. The one or more implantable stimulating electrodes can deliver the configured stimulation to another portion of one or more subdiaphragmatic branches of the patient's vagus nerve.

This invention discloses a flexible electrode array, system, and manufacturing method for closed-loop neural modulation, relating to the fields of neural engineering, medical devices, and biosensor technologies. The flexible electrode array includes a flexible biocompatible substrate, a recording electrode array, and a stimulating electrode array. The recording sites are arranged in a matrix, and the stimulating sites are coplanar with the recording sites, located between or within rows of the recording electrode array, achieving a spatially co-located layout of recording and stimulation. The system also includes an external control unit for receiving neural signals acquired by the recording electrode array and dynamically adjusting the stimulation parameters applied to the stimulating electrode array based on the neural signals. This application improves biocompatibility, achieves high-resolution signal mapping, and enables efficient closed-loop neural modulation by shortening the spatiotemporal distance between stimulation and monitoring.

An intracardiac pulse field ablation (PFA) system comprising a catheter, a constant current AC signal generator, and at least one computing device, wherein the PFA catheter comprises at least a first constant AC current injection electrode, second and third sensing or recording electrodes, and a fourth ablation electrode, the PFA catheter and the electrodes thereof being configured to be operably connected to the constant current AC signal generator, and at least one computing device, the first electrode being a signal injection electrode configured to inject constant current AC signals into or near the patient's cardiac tissue, the second and third electrodes being recording or sensing electrodes configured and located sufficiently close to the first electrode to permit differential sensing and measurement of complex electrical impedance signals, including the phase and amplitude thereof, resulting from injection of the constant current AC signals into the cardiac tissue from the first electrode.

The application discloses a wireless flexible cortex brain-computer interface device based on ultrasonic energy supply and a signal acquisition method thereof. The device comprises an extracorporeal ultrasonic transceiving unit and a passive flexible intracorporeal implant unit. The intracorporeal implant unit comprises a flexible substrate, a recording electrode unit arranged on the side of the flexible substrate facing the cerebral cortex, and a piezoelectric transducing unit and a load modulation unit arranged on the back side or lateral area of the flexible substrate. The piezoelectric transducing unit receives extracorporeal ultrasonic waves and converts them into electric energy. The load modulation unit adjusts the port load impedance of the piezoelectric transducing unit in a continuous analog mode according to the cortical electrophysiological signals collected by the recording electrode unit, thereby modulating ultrasonic backscattering echoes. The extracorporeal ultrasonic transceiving unit receives and demodulates the backscattering echoes to reconstruct the cortical electroencephalogram signals. The application can realize wireless acquisition of the cortical electroencephalogram signals without the need of intracorporeal batteries and transcutaneous leads, and improve long-term implant stability in a flexible cortex attachment state.

An intracardiac pulse field ablation (PFA) system comprising a catheter, a constant current AC signal generator, and at least one computing device, wherein the PFA catheter comprises at least a first constant AC current injection electrode, second and third sensing or recording electrodes, and a fourth ablation electrode, the PFA catheter and the electrodes thereof being configured to be operably connected to the constant current AC signal generator, and at least one computing device, the first electrode being a signal injection electrode configured to inject constant current AC signals into or near the patient's cardiac tissue, the second and third electrodes being recording or sensing electrodes configured and located sufficiently close to the first electrode to permit differential sensing and measurement of complex electrical impedance signals, including the phase and amplitude thereof, resulting from injection of the constant current AC signals into the cardiac tissue from the first electrode.

A spinal cord stimulator (SCS) system and method for placing SCS electrodes in a patient for spinal cord stimulation therapy. The SCS system comprises a stimulator and an amplifier unit. The amplifier unit comprises an algorithm module to store and process algorithms for processing data received from recording electrodes placed in a patient's body. The recording electrodes send real-time electromyography (EMG) data related to the patient to the algorithm module. The algorithm module processes the real-time EMG data, including filtering the EMG data to remove artifacts generated by the SCS electrodes. The SCS system compares the filtered EMG data in real-time with the pre-clinical EMG data and displays the comparison data on the display device. The displayed data is used, by the surgeon, for lateralization of the SCS electrode.

A spinal cord stimulator (SCS) system and method for placing SCS electrodes in a patient for spinal cord stimulation therapy. The SCS system includes a stimulator and a base unit. In conjunction with a machine learning (ML) block, the base unit includes an algorithm module to store and process algorithms for processing data received from recording electrodes placed in a patient's body. The recording electrodes send electromyography (EMG) data to the algorithm module. The algorithm module processes and sends the EMG data to a display device. The displayed data is used, by a surgeon, for lateralization of the SCS electrode. The SCS system further includes algorithms to adjust stimulation parameters related to SCS electrodes based upon the surgeon's workflow. Further, the SCS system allows manual modification of stimulation parameters based upon muscle responses and the EMG data from the recording electrodes.

The recording electrode (1) for measuring the electrophysiological signal from biological tissue is particularly suitable for use in magnetic stimulation. This recording electrode is provided with a contact area (2) designed to come into contact with biological tissue by direct contact or through electro-conductive gel to facilitate sensing of the electrophysiological signal from the biological tissue to the contact area (2), where the contact area (2) is electrically connected to the output of the recording electrode (1) for conducting the electrophysiological signal for further processing. The contact area (2) of the recording electrode (1) is divided into at least two separate contact areas (3) electrically separated from each other, each separate contact area (3) being connected to the output of the recording electrode (1) via its own resistor (4), whose electrical resistance is at least 100 Ω, while the resulting resistance of all resistors connecting the individual separate contact areas (3) with the output of the recording electrode (1), as measured between the biological tissue and the output of the recording electrode (1), is at least 50 Ω, which corresponds to at least half the size of the impedance of the biological tissue in magnetic stimulation.

The invention discloses an electrode cap and a system. The electrode cap comprises a supporting body; the electrode base comprises a hollow structure defined by side walls, and the electrode base is fixed to the supporting body; the electroencephalogram recording electrode is arranged on the side wall of the electrode base, and the sensing end of the electroencephalogram recording electrode is arranged in the hollow structure; the stimulating electrode base is detachably connected with the electrode base and arranged in the hollow structure, and a stimulating electrode is integrated at the bottom of the stimulating electrode base; a containing space is arranged in the stimulating electrode base, and a conducting medium injection hole communicated with the containing space is further formed in the top of the stimulating electrode base. According to the invention, electroencephalogram acquisition and electrical stimulation can be carried out at the same point and at the same time, and closed-loop stimulation is realized.

A neural stimulus comprises at least three stimulus components, each comprising at least one of a temporal stimulus phase and a spatial stimulus pole. A first stimulus component delivers a first charge which is unequal to a third charge delivered by a third stimulus component, and the first charge and third charge are selected so as to give rise to reduced artefact at recording electrodes. In turn this may be exploited to independently control a correlation delay of a vector detector and an artefact vector to be non-parallel or orthogonal.

The application discloses a glasses leg structure type electroencephalogram collection electrode and intelligent electroencephalogram collection glasses, and belongs to the technical field of brain-computer interfaces. The electrode comprises a recording electrode integrated in the inner side of a glasses leg, a reference electrode integrated in a nose pad and a signal transmission circuit. The recording electrode is attached to the head to collect electroencephalogram signals, the reference electrode provides a reference potential, and the signal transmission circuit is connected to a signal processing module. The intelligent electroencephalogram collection glasses further comprise a glasses frame, a power module and an optional eye movement tracking module. The glasses can fuse electroencephalogram signals and eye movement signals, and output control instructions after feature extraction, customized combination and intention recognition. The electrode and the glasses are designed in an integrated manner, and the wearing comfort and signal collection stability are considered, so that the non-invasive and convenient collection of electroencephalogram signals is realized, and the glasses are suitable for daily use.

The present disclosure discloses a wristband nerve stimulator applicable to both the left and right hands and a use method thereof. The wristband nerve stimulator includes a fixed main unit and an electrode piece band; a groove and an adapter port are respectively arranged on two sides of a bottom of the fixed main unit; a controller is arranged in the fixed main unit; the controller includes a main control unit (MCU), an intelligent identification unit, a storage unit and a stimulation unit; the electrode piece band comprises a base and an electrode assembly; adapter seats are arranged on two sides of a top surface of the base; a memory IC is arranged in the base; the memory IC is provided with an independent identification ID and can record the number of use or the service life of the electrode piece band.

A burr hole device is configured to receive a catheter and a cable of a sheath. The sheath is configured to receive a portion of the catheter and has an electrode. When the catheter and sheath are implanted with the burr hole device, the catheter and electrode of the sheath are implanted in a brain. Systems and apparatuses may include the burr hole device and / or a cranial port device, the catheter, and the sheath.

The application belongs to the technical field of brain-computer interface, and provides a self-generated neural electrode, which comprises a flexible insulating base, a surface insulating layer arranged on the flexible insulating base, and a conductive metal layer arranged between the flexible insulating base and the surface insulating layer, wherein the conductive metal layer is patterned to form a neural recording electrode array and a micro biological fuel cell unit; a window is arranged on the surface insulating layer to expose electrode sites of the neural recording electrode array and at least part of an electrode surface of the micro biological fuel cell unit; a precursor storage structure is arranged at the exposed electrode sites of the neural recording electrode array, and the precursor storage structure contains a medium containing a first precursor; the micro biological fuel cell unit is configured to generate a micro current after being implanted into a living body, and drive the first precursor to generate an in-situ electrochemical reaction at an interface of the neural recording electrode array, so as to generate conductive nanoclusters, and effectively solve the pain point of signal attenuation caused by long-term implantation.

The invention discloses a multifunctional optical flexible nerve probe and a nerve regulation and control system, and belongs to the technical field of nerve engineering. The probe comprises a laminated flexible main body made of PDMS, and a recording electrode, a micro light-emitting diode, at least two drug delivery channels and a rigidity regulation and control channel are integrated in the laminated flexible main body; the edge of the probe is provided with a wave-shaped outline, and the medicine outflow holes are formed in the wave crests to form an anti-blocking liquid storage cavity. The rigidity regulation and control channel can be filled with a phase change material (such as gallium) or magnetorheological fluid, and rigidity dynamic switching of hardening when the probe is implanted and softening after implantation is realized through external temperature or magnetic field control. The technical problems that a flexible probe is difficult to implant, and a rigid probe is large in long-term damage and single in function are solved, and multi-mode nerve interaction which is controllable in implantation rigidity and good in long-term biocompatibility and integrates current recording, light stimulation and reliable drug delivery is achieved.

The application discloses a kind of multi-functional optical flexible nerve probe and nerve control system, belong to neural engineering technical field.The probe includes by PDMS made of laminated flexible main part, it is integrated with recording electrode, micro light emitting diode, at least two drug delivery channels and a rigidity control channel;Probe edge has wavy profile, and drug outflow hole is arranged at wave crest to form anti-blocking liquid storage cavity.Rigidity control channel can be filled with phase change material (such as gallium) or magnetic rheological fluid, and the rigidity dynamic switching of hardening when probe implantation and softening after implantation is realized by external temperature or magnetic field control.The application solves the technical problems of flexible probe implantation difficulty, rigid probe long-term damage and single function, realizes implant rigidity controllable, long-term biocompatibility is good, and multi-modal nerve interaction of integrated electric recording, light stimulation and reliable drug delivery.

The invention relates to a method for performing a medical procedure, the method consisting of: providing a probe having a known spring constant for insertion into the body of a patient, the probe having electrodes and positioning sensors at respective locations along the probe; and when the probe is in an unlimited state, recording relative position coordinates of the electrode and the positioning sensor. When the probe is in the patient and is deformed by contact with the tissue of the patient, changes in the relative position coordinates of the positioning sensor and the electrode in contact with the tissue are recorded, and in response to the recorded changes, the shape of the probe in the deformed state is calculated. A respective force exerted by the tissue on each of the electrodes is calculated in response to a known spring constant and the calculated probe shape, and an electrical signal from the tissue through the electrodes is controlled in response to the calculated respective forces on the electrodes.