The invention discloses a mechanical stimulation set and self-adaptation capsule casing device for treating sarcopenia. The mechanical stimulation set achieves the technical purpose that pressure is precisely applied to muscle tissue for vibration to treat sarcopenia. According to the adopted technical scheme, the mechanical stimulation set for treating sarcopenia comprises a vibrating device, a deformable trigger plate, an air source system and an air bag, the vibrating device can drive the deformable trigger plate to reciprocate to generate vibration stimulation to skin; the air source system can inject exhaust gas to the air bag, the air bag directly or indirectly applies pressure to muscle tissue, mechanical stimulation for vibrating and applying pressure to the muscle tissue is performed, micro-circulation of lower limb muscle tissue is improved, and the purpose of treating sarcopenia is achieved. The self-adaptation capsule casing device for treating sarcopenia comprises a leg sleeve, the leg sleeve is of a dual-layer structure, a cavity is formed between the inner layer and the outer layer, the mechanical stimulation set for treating sarcopenia is arranged inside the cavity,and the deformable trigger plate is attached to the inner layer of the leg sleeve.