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Temperature self compensation method for LAPS (Light Addressable Potentiometric Sensor)

A potential sensor, self-compensation technology, applied in the sensor field, can solve the problems of no LAPS temperature self-compensation, affecting the output stability and measurement accuracy of the LAPS sensor, limiting practical applications, etc., to improve the detection accuracy and reduce the external environment temperature cross-sensitivity the effect of

Active Publication Date: 2016-02-03
GUILIN UNIV OF ELECTRONIC TECH
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Problems solved by technology

At present, researchers have realized the detection of cells, spores, proteins, ions, etc. by LAPS under laboratory conditions; however, the sensor with this EIS structure is easily affected by the ambient temperature, which affects the output stability and measurement accuracy of the LAPS sensor. limit its practical application
Temperature compensation is one of the key technologies to be solved when the sensor is put into practical use, but there is no research on LAPS temperature self-compensation

Method used

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  • Temperature self compensation method for LAPS (Light Addressable Potentiometric Sensor)
  • Temperature self compensation method for LAPS (Light Addressable Potentiometric Sensor)
  • Temperature self compensation method for LAPS (Light Addressable Potentiometric Sensor)

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Embodiment Construction

[0017] The present invention will be further described in detail below with reference to the accompanying drawings and embodiments, but is not limited to this embodiment.

[0018] figure 1 It is a schematic diagram of the principle of LAPS temperature self-compensation. The LAPS system was used to detect the concentration of PBS buffer solution at different temperatures, the LAPS temperature self-compensation model was established by the support vector machine (SVM) algorithm, and the temperature compensation effect was finally evaluated. The specific steps are as follows:

[0019] 1. Acquisition of training samples: figure 2 Schematic diagram of the LAPS test system. pass figure 2 The LAPS test system shown, for PBS buffers at different temperatures (10°C, 15°C, 20°C, 25°C, 30°C, 35°C) and different pH values ​​(pH=6.00, 6.50, 7.00, 7.50, 8.00) Each test was performed 5 times, and a total of 150 groups of data samples were measured.

[0020] 2. Feature extraction: Use ...

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Abstract

The invention discloses a temperature self compensation method for a LAPS (Light Addressable Potentiometric Sensor). A corresponding relationship between the magnitude of saturated photocurrent outputted by the LAPS and environmental temperature is used, and through extracting the saturated photocurrent outputted by the LAPS, temperature self compensation is carried out on the LAPS. In a condition with variable temperature, the corresponding relationship between the magnitude of the saturated photocurrent outputted by the LAPS and the environmental temperature is determined, and a LAPS temperature-saturated photocurrent feature curve is made; and the magnitude of the saturated photocurrent is extracted from an experimental data sample to serve as an input characteristic quantity for the environmental temperature, and a LAPS temperature self compensation model is built through software algorithm. According to LAPS output, through the temperature self compensation fusion processing, temperature compensation is carried out according to the temperature characteristic quantity, and the measured parameter is accurately detected. An experimental result shows that the LAPS temperature self compensation can eliminate temperature influences, the LAPS system testing precision is improved, and the method can be used for pH value detection for a buffer solution.

Description

technical field [0001] The invention relates to the technical field of sensors, in particular to a temperature self-compensation method of a sensor. Background technique [0002] Light-addressable potential sensor (LAPS) is an electrolyte-insulator-semiconductor (EIS) structure device, which can detect the amplitude and phase changes of surface potential caused by redox reactions, immune reactions, and enzymatic reactions. various parameters. At present, researchers have realized the detection of cells, spores, proteins, ions, etc. by LAPS under laboratory conditions; however, the sensor with this EIS structure is easily affected by the ambient temperature, which affects the output stability and measurement accuracy of the LAPS sensor. limited its practical application. Temperature compensation is one of the key technologies to be solved when the sensor is put into practical use, but there is no research on LAPS temperature self-compensation. SUMMARY OF THE INVENTION ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01D3/036
Inventor 梁晋涛邱恒明周治德李桂银黄勇
Owner GUILIN UNIV OF ELECTRONIC TECH
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