2623results about How to "Improve long-term stability" patented technology

Positional information of a movable body in a Y-axis direction is measured using an interferometer and an encoder whose short-term stability of measurement values excels when compared with the interferometer, and based on the measurement results, a predetermined calibration operation for obtaining correction information for correcting measurement values of the encoder is performed. Accordingly, by using measurement values of the interferometer, correction information for correcting the measurement values of the encoder whose short-term stability of the measurement values excels the interferometer is obtained. Then, based on the measurement values of the encoder and the correction information, the movable body is driven in the Y-axis direction with good precision.

The present invention provides a polymer membrane enhanced with cured epoxy resin for use as the outer membrane of biosensors. The membrane includes approximately 30-80% epoxy resin adhesives, 10-60% polymer such as poly(vinyl chloride), polycarbonate and polyurethane and 0-30% plasticizers and 5-15% surface modifier reagent such as polyethylene oxide-containing block copolymers. Utilizing the polymer membrane of the present invention, a three-layered sensing element has been developed. This sensing element will be particularly useful for miniaturized biosensors used for in vitro blood measurements or for continuous in vivo monitoring such as implantable biosensors. This element includes an enzyme layer, an interference-eliminating layer and the novel polymer member of the present invention as the outer polymer layer. This novel sensing element shows excellent response characteristics in solutions and has an extremely long lifetime. This technology is particularly useful for improving the lifetime of implantable biosensors.

Methods and compositions are disclosed for the preparation of free radical scavenging polymers and polymer films functionalized with antioxidants. Enzymatic and chemical tailoring of monomers with antioxidants followed by enzymatic polymerization is described. These antioxidant functionalized polymers can increase shelf life and quality of food products, as well as, increase effectiveness of pharmaceutical agents when used as packaging or as coatings on packaging for oxygen sensitive materials. The novel enzymatic covalent coupling of antioxidants to a polymer enhances the free radical scavenging ability of packaging while also inhibiting the escape of the antioxidants, and thus limiting exposure and/or absorption by an individual. In addition to its use in food or pharmaceutical packaging, methods are disclosed for using the antioxidant coupled polymers in a variety of applications including as coatings on the inside of medical devices, such as stents and catheters, which would substantially reduce free radical damage and/or oxygen depletion during medical procedures. Furthermore, through the coupling of antioxidants to biodegradable polymers, controlled delivery and sustained release of an antioxidant to a subject is possible.

A method of spectrally broadening light pulses includes the steps of providing the light pulses with a laser source, said light pulses having a pulse duration below 1 ps, in-coupling the light pulses into a hollow optical waveguide device, and spectrally broadening the light pulses propagating along the pulse guiding medium by subjecting them to a Raman nonlinearity via excitation of a Raman polarization having a first Raman period, wherein the optical waveguide device subjects the light pulses to anomalous group velocity dispersion which combines with the spectral broadening of the light pulses to result in a Raman-enhanced self-compression of the light pulses, and the light pulses further propagate along the optical waveguide device such that the Raman-enhanced self compression results in a further excitation of a Raman polarization having a second Raman period which is faster than the first Raman period.

3D accelerometer for measuring three components of inertial force (or acceleration) vector with respect to an orthogonal coordinate system, which has high sensitivity due to a big proof mass located within a cavity beneath the surface of the sensor die. The size of the cavity and the size of the proof mass exceed the corresponding overall dimensions of the elastic element. The sensor structure occupies a very small area at the surface of the die increasing the area for ICs need to be integrated on the same chip.

A Connector Position Assurance (CPA) device for ensuring mating of a male header connector with a female housing includes a body portion, a first arm, and a second arm. The first arm is attached to the body portion, extended from the body portion, and includes a locking groove proximate a distal end thereof. The second arm, which includes a locking latch, is spaced apart from the first arm, attached to the body portion, and extended from the body portion. When the CPA device is guided along the female housing, the locking groove and the locking latch lock onto complementary protrusions on the female housing in a pre-lock position, only to be dislodged upon contact of a sloped surface at the distal end of the first arm with the male header connector during insertion of the male header connector into the female housing to proceed to a final-lock position.

A system and method for inputting motion measurement data into a computationally based device are provided. In a first version three-axis accelerometer determines components of an inertial force vector with respect to an orthogonal coordinate system. The accelerometer includes a sensor die made of a semiconductor substrate having a frame element, a proof mass element, and an elastic element mechanically coupling the frame and the proof mass. The accelerometer also has three or more stress-sensitive IC components integrated into the elastic element adjacent to the frame element for electrical connectivity without metal conductor traversal of the elastic element.

A detector for determining a position of at least one object, where the detector includes: at least one optical sensor, where the optical sensor has at least one sensor region, where the optical sensor is designed to generate at least one sensor signal in a manner dependent on an illumination of the sensor region by illumination light traveling from the object to the detector; at least one beam-splitting device, where the beam-splitting device is adapted to split the illumination light in at least two separate light beams, where each light beam travels on a light path to the optical sensor; at least one modulation device for modulating the illumination light, where the at least one modulation device is arranged on one of the at least two light paths; and at least one evaluation device, where the evaluation device is designed to generate at least one item of information from the at least one sensor signal.

The present invention comprises the discovery and development of an effective cryoprotectant composition, without containing skim milk or any other animal-derived compounds, to achieve long-term stability of freeze-dried lactic acid bacteria (LAB), at different temperatures, whereby the retention of viability of the freeze-dried LAB after 6 months of storage, preferably after 9 months of storage, more preferably after 12 months of storage is more than 50%. The invention is in the field of producing freeze dried bacteria, in particular Lactic acid bacteria. More in particular, the invention relates to the use of a novel combination of cryoprotectants for increasing the viability of bacteria after freeze drying, improving the texture of the lyofilized cake for easy grinding and improving the long term stability of the freeze dried bacteria at different temperature conditions. The invention further relates to such freeze dried bacteria for use in food industry or in human or animal health applications. More in particular, the invention relates to the increased viability and long-term storage of recombinant bacteria capable of expressing heterologous proteins or peptides and administered to humans or animals for therapeutic or vaccination purposes.

The present invention relates to an improved catalyst for direct conversion of methane to ethane and ethylene, a method for producing the catalyst and a process making use of the catalyst.

The present disclosure is directed to stable pharmaceutical formulations and uses thereof.

First positional information of a stage is measured using an interferometer system, for example, an X interferometer and a Y interferometer. At the same time, second positional information of the stage is measured using an encoder system, for example, one X head and one Y head. A coordinate offset is set by performing a moving average of the difference between the first positional information and the second positional information for over a predetermined measurement time, and the reliability of output signals of the encoder system is verified using the coordinate offset. In the case the output signals are determined to be normal, the stage is servocontrolled using the sum of the first positional information and the coordinate offset. Such servocontrol by a hybrid method makes it possible to perform drive control of the stage having stability of the interferometer and accuracy of the encoder together.

The invention belongs to the technical field of preparation of super-hydrophobic surfaces, and relates to a preparation method for a super-hydrophobic surface with a bionic micro-nano composite structure. From the angle of the super-hydrophobic surface, the super-hydrophobic surface is prepared by virtue of a mesoscale two-step etching method; etching treatment is carried out on a substrate surface twice; a micro-nano composite structure similar to a lotus leaf surface is constructed by utilizing a chemical or an electrochemical reaction etching substrate, and surface modification is carried out by virtue of a surface modifier to reduce surface free energy. The size of the micro-nano structure can be controlled by virtue of reaction time, a reaction temperature and concentration. A contact angle, on the surface of the micro-nano composite structure, of water drops is as high as 170 degrees while a rolling angle of the water drops is smaller than 5 degrees. According to electrochemical test results, corrosion resistance of a super-hydrophobic stainless steel sheet is 22 times that of common stainless steel. The method provided by the invention does not need special equipment, is low in cost, good in stability, excellent in super-hydrophobic property, good in corrosion resistance and can be applied to metal corrosion-resistant protection.

A GMR sensor element is proposed, having a rotationally symmetrical positioning of especially eight GMR resistor elements which are connected to each other to form two Wheatstone's full bridges. This GMR sensor element is especially suitable for use in an angle sensor for the detection of the absolute position of the camshaft or the crankshaft in a motor vehicle, particularly in the case of a camshaft-free engine having electrical or electrohydraulic valve timing, of a motor position of an electrically commutated motor, or of detection of a windshield wiper position, or in the steering angle sensor system in motor vehicles.

A device for delivering a drug includes a housing; at least one nozzle at a portion of the housing; a source of drug in the housing; and an energy source for providing a pressure of up to about 2,000 psi for driving the drug through the at least one nozzle and out of the housing. The drug is delivered to tissue under microjet propulsion. The device is particularly useful for drug delivery applications such as transdermal and ocular by way of example.

A photovoltaic cell includes a first substrate having on its surface a first electrode layer having on its surface a semiconductor film on which a photosensitizer is adsorbed, and a second substrate having on its surface a second electrode layer. The first and second substrates are arranged so that the first electrode layer overlaid with the semiconductor film and the second electrode layer are opposite each other with an electrolyte disposed therebetween. Spacer particles are interposed between the semiconductor film and the second electrode layer, and at least one of the electrode-layer-having substrates is transparent. A coating liquid for forming the semiconductor film includes both a component for forming the semiconductor film as well as the spacer particles, dispersed in a dispersion medium.

An electrooptically tunable waveguide-coupled microresonator. In one example embodiment, the switch includes a photoalignment layer that enhances control of liquid crystal alignment in the cladding near the coupling region of the microresonator and waveguide.

A method comprising determining coordinates of a first point rigidly attached to a rigid body floating on the sea surface in a desired coordinate reference frame; measuring orientation parameters of the rigid floating body to determine 3D offset in the coordinate reference frame of the first point to any point on or rigidly attached to the body; applying a 3D coordinate shift from the first point to a second point rigidly attached to the body, thus determining coordinates of the second point in the desired reference frame; determining a distance from the second point to one or more devices that are components of a seismic acquisition spread, by comparing transmission times of a signal to recording times of transmitted signals and multiplying by a signal propagation rate; and determining relative positions of components of the spread to each other and to devices rigidly attached to the rigid body.

The invention discloses PTC graphene heating printing ink and a preparation method thereof. The PTC graphene heating printing ink is prepared from the following components in percentages by mass: 50% to 70% of a binder, 9% to 21% of a solvent, 1% to 3% of an additive, 10% to 20% of a conductive filler and 5% to 20% of a PTC functional material. The preparation method comprises the following steps: (1) firstly stirring and dispersing the binder, the solvent and the additive for 20 to 30 min, then adding the PTC functional material into stirring equipment for stirring for 8 to 12 min, and finally adding the conductive filler for uniform stirring to obtain a coarse paste; and (2) carrying out four to six times of three-roller grinding on the coarse paste so as to obtain the PTC graphene heating printing ink. The invention also discloses a heating film. The heating film comprises an organic polymer base material film, the PTC graphene heating printing ink, a conductive silver paste, conductive copper foil and an organic polymer adhesive film. The PTC function of the graphene heating film is increased, the potential safety hazard problem of an existing graphene heating film is eliminated, and the practicability is improved.