38 results about "Bacterial composition" patented technology

The invention discloses an intestinal bacterial composition for improving a cognitive function and relieving neuroinflammation and an application of the intestinal bacterial composition, and belongs to the technical field of biomedicine and microbiology, the intestinal bacterial composition is composed of a Lachnospiraceae bacterium, a Bacteroides multiforme and a Roseburiatestinae bacterium, and the intestinal bacterial composition is prepared from the following raw materials of the following raw materials of the intestinal bacterial composition: the Lachnospiraceae bacterium, the Bacteroides multiforme and the Roseburiatestinae bacterium, the Roseburiatestinae bacterium, the Roseburiatestinae bacterium, the Roseburiatestinae bacterium, the Roseburiatestinae bacterium, the Roseburiatestinae bacterium and the like. Experimental research results show that a modular synergistic effect exists among the helicobacter hirsuticus, the bacteroides multiforme and the Roche enterobacter, and the pharmaceutical composition has a remarkable neuroprotective effect on a cognitive impairment mouse model and an Alzheimer disease mouse model, can improve the cognitive function and relieve neuroinflammation, and can be used for preparing a neuroprotective agent for treating the cognitive impairment mouse model and the Alzheimer disease mouse model. A new thought and method can be provided for treatment of cognitive impairment related diseases and neuroinflammation related diseases.

The invention relates to a bactericidal composition containing fluxapyroxad and thiediazole copper. The bacterial composition is compounded from fluxapyroxad and thiediazole copper in a binary mode, wherein a mass ratio of fluxapyroxad to thiediazole copper is (1-50) to (50-1); a mass fraction of fluxapyroxad and thiediazole in the preparation is 1%-80%, and the rest of the preparation is auxiliary components which are allowed to use and are acceptable in a pesticide. A dosage form of the bactericidal composition is missible oil, a suspending agent, wettable powder, a water dispersible granule, emulsion in water, microemulsion, a granule and a micro-capsule. The bactericidal composition is mainly used for controlling plant gray mold, peronospora and phytophthora germs.

The present application relates to probiotic compositions, e.g., comprising at least one bacterial strain selected from: Bifidobacterium longum, Bifidobacterium breve, and Bifidobacterium infantis, or from Streptococcus thermophiles, Lactobacillus acidophilus, Lactobacillus plantarum, and Lactobacillus paracasei, and methods for use thereof.

Aspects of the disclosure relate to compositions and methods for modulating the immune response of a subject. The disclosure is based, in part, on compositions comprising a bacterial consortium that promotes interferon (IFN) response in the gut microbiome of a subject and enhances the anti-tumor effects of certain immune checkpoint inhibitor (ICI) therapies. In some embodiments, the compositions are useful for treating a subject having cancer.

The present invention relates to the use of a bacterial composition having an arginine deaminase activity (inhibition of nitric oxide synthase by converting L-arginine to L-citrulline) of 11,000 μmol L-citrulline / h / g of composition and a sphingomyelinase (ceramide production) activity of 0.01-1,000 nanomoles ceramide / h / g of composition in the treatment and / or prevention of respiratory tract diseases caused by viruses such as influenza viruses, coronaviruses such as SARS-CoV, MERS-CoV and SARS-CoV-2, avian viruses, respiratory syncytial virus (RSV), rhinoviruses, pneumoviruses, or respiratory failure induced or exacerbated by viral infection, angina pectoris, cor pulmonale, dyspnea, pulmonary edema, neonatal asphyxia, myocardial infarction, heart failure, respiratory failure, Pickwickian syndrome, pulmonary hypertension, pneumonia, or even cystic fibrosis (CF) exacerbated by viral infection.

Use of a composition comprising bacteria for odor reduction in the treatment of symptoms of tissue necrosis, wound secretions or putrid wounds or a disease selected from the group consisting of ozena, hyperhidrosis, osmidrosis, chronic urinary tract infections, chlamydial infections and halitosis; wherein the composition comprises the bacteria Lactobacillus acidophilus TYCA15, Lactobacillus salivarius, Bifidobacterium animalis, Bifidobacterium bifidum and Bifidobacterium longum in the ratio 1:1:1:1:1; and the composition totals 10 9 bacteria per gram of the composition.

The invention relates to a polynucleotide comprising a lacZ gene (lacZFS) encoding a β-galactosidase characterized by a particular profile with respect to its lactose hydrolysis efficiency. The invention also relates to a strain of Streptococcus thermophilus comprising a lacZFS allele and a bacterial composition thereof, and its use for obtaining fermented milk that does not undergo subsequent acidification.

Disclosed herein are bacterial compositions and methods for treating neurological disorders, improving brain function, and reducing stress.

The application discloses a di(2-ethylhexyl) phthalate degrading bacterium, a bacterial composition and application thereof. The degrading bacterium is named Sphingomonas parapaucimobilis GHQ28 and Stenotrophomonas maltophilia GHQ31. Research finds that GHQ28 and GHQ31 have chemotaxis to DEHP and downstream metabolites thereof, and there is a synergistic interaction between the two bacteria; the growth and DEHP degradation speed of the two strains under co-culture conditions are faster than that under single culture conditions. The bacterial composition composed of the two strains has a highest degradation rate of 99.2±0.59% to 400mg / L DEHP within 72h, compared with single culture, the total biomass is increased by 1.4-50.3 times, and the DEHP degradation rate is increased by 1.07-58.82 times. The application provides a new technical means for remediation of DEHP contaminated soil or water.

The present invention consists in combining low dose intestinal radiation (ILDR) with immunotherapy or other antineoplastic treatments, in the ideal context of intestinal presence or prevalence of Christensenellaceae family members, especially for solid cancers at an advanced stage (refractory to first line chemo or immunotherapy). The invention also pertains to a bacterial composition,e.g. comprising Chistensenella bacteria, for use in the treatment of cancer in a patient, in combination with intestinal low dose radiotherapy (ILDR) and an antineoplastic treatment.

The invention provides a pseudomonas bacterium composition, a complex microbial inoculant and application of the pseudomonas bacterium composition and the complex microbial inoculant, and belongs to the technical field of microorganisms. The invention provides a Pseudomonas bacteria combination, which comprises Pseudomonas bacteria JF1 and Pseudomonas hutmensis JF2, the Pseudomonas bacteria JF1 and the Pseudomonas hutmensis JF2 are growth-promoting bacteria screened from rhizosphere soil of rhizoma corydalis, and the Pseudomonas bacteria JF1 and the Pseudomonas bacteria JF2 have the capabilities of dissolving phosphorus and producing siderophores, can be used as growth promoting agents in a synergistic manner to promote the growth of rhizoma corydalis seedlings, and can be used for promoting the growth of rhizoma corydalis seedlings. The method has a remarkable effect of promoting accumulation of the total alkaloid content in rhizoma corydalis tubers, can be used for artificial cultivation of rhizoma corydalis, provides a theoretical basis for improving the yield and quality of rhizoma corydalis, and has important guiding significance for reasonably and effectively utilizing microorganisms to improve the quality and yield of Qinshi medicine-rhizoma corydalis.

The invention relates to a polynucleotide comprising a lacZ gene (lacZFS) encoding a β-galactosidase characterized by a particular profile regarding its efficiency of hydrolysis of lactose. The invention is also directed to a Streptococcus thermophilus strain comprising a lacZFS allele and bacterial composition thereof, and their use to obtain fermented milk not undergoing post-acidification.

Provided herein are bacterial compositions that are useful for treating and preventing complications and side effects associated with a disease or disorder, such as those associated with dysbiosis of a gastrointestinal tract. The bacterial compositions disclosed herein are designed to exhibit one or more functional features that are useful for the treatment of such diseases and disorders.

The invention provides a method for obtaining one or more supporting bacteria for a bacterial composition. The invention further provides devices and kits, which may be used in such methods, and uses of such devices and kits. Such supporting bacteria may be suitable for formation of synthetic bacterial consortia.

The present invention relates to bacterial strains and compositions, and their use for controlling diseases in plants and for promoting plant growth. In one aspect, the isolated bacterial strain RR15 of the genus Pantoea, deposited under Accession Number V22 / 011015 on 9 June 2022 with the National Measurement Institute, Australia, is provided. Methods for promoting plant growth, promoting plant tuber growth, inhibiting plant root infection by a pathogen, and inhibiting plant root disease by a pathogen, using the bacterial strains and compositions are also provided

An Acinetobacter pittii strain is provided, which is Acinetobacter pittii FL3-2 with a deposit number of CCTCC NO: M20232618. A bacterial composition is provided, which includes the Acinetobacter pittii FL3-2 as an active component. A method for phosphorus removal from a sewage sample is also provided, in which the Acinetobacter pittii FL3-2 is inoculated into the to-be-treated sewage sample.

A bacterial composition for substrate inoculation to improve fertility of the substrate includes a predetermined concentration of at least one strain of autotrophic bacteria, wherein the autotrophic bacteria is characterised in having the ability to produce organic compounds in a predetermined substrate; and a predetermined concentration of at least one strain of mineral nutrient producing bacteria selected from a group including diazotrophic bacteria, potassium solubilizing bacteria and phosphate solubilizing bacteria, wherein the bacteria is characterised in having the ability to produce mineral nutrients in such predetermined substrate. The substrate inoculation of the autotrophic bacterial portion of the composition increases production of metabolizable forms of organic compounds, and inoculation of the mineral nutrient producing bacterial portion of the composition metabolizes the increased organic compounds for an increased production of metabolizable forms of mineral nutrients in the predetermined substrate.

The present disclosure relates to a bacterial composition, a method of producing a bacterial composition and various uses of the bacterial composition.

Escherichia coli is a widely studied model organism and an integral component of the human gut microbiome, offering significant potential for bacteria-based therapeutic applications. However, engineering native E. coli strains poses persistent challenges. In this study, the chassis- independent recombinase-assisted genome engineering technique was leveraged to engineer the native gut strain E. coli EcAZ-1 and the probiotic strain E. coli Nissle 1917 (EcN). The bioluminescent lux operon, green fluorescent protein (GFP), and the oxygen-independent fluorescent protein IFP 2.0 were successfully introduced into both strains. To further enhance IFP 2.0 fluorescence, a heme oxygenase was co-expressed, and the chromophore biliverdin was supplemented, achieving robust IFP 2.0 expression under both anaerobic and aerobic conditions. Also, both strains were engineered to biosynthesize bioactive compounds, including the plant- derived flavonoid naringenin and mycosporine-like amino acids. The results underscore the potential of native E. coli strains as flexible and robust platforms for synthetic biology, enabling novel applications in biomedical research and therapeutics. Based on these results, this application provides recombinant bacteria generating IFP2.0 fluorescence under anaerobic condition, bacterial composition for gastrointestinal cancer detection and use method thereof, and naringenin or MAA overproducing recombinant bacteria.

The invention discloses a separation device for producing an anti-bacterial composition and a preparation process, and particularly relates to the technical field of sugar derivates, the separation device comprises a supporting frame, a separation tank is fixedly installed in the middle of the supporting frame, and a storage barrel is installed on one side of the outer surface of the separation tank; a separation mechanism for separating antibacterial compositions is installed on the upper portion of an inner cavity of the separation tank, a flow guide ring groove is formed in the upper side of the middle of an inner cavity of the storage barrel, a discharging mechanism is arranged in the inner cavity of the separation tank, and a driving assembly is arranged at the bottom of the inner cavity of the separation tank. According to the separation device for production of the anti-bacterial and bacteriostatic composition, attached residues can be rolled and extruded in the separation process of the anti-bacterial and bacteriostatic composition through the arranged separation mechanism, secondary deep separation can be conducted on solid impurities in sticky materials, adsorption combination of the solid impurities and liquid is effectively broken, and the separation efficiency is improved. The separation efficiency of solid impurities and liquid is remarkably improved, the component residual rate is reduced, and the recovery rate of target components is effectively improved.

Compositions for the prevention and control of bacterial speck of tomato are described. The compositions comprises comprises an aqueous mixture of living Bacillus subtilis and living Bacillus pumilus. The compositions have been shown to be highly effective in the field. Also described are methods of use and kits comprising the compositions.

The disclosure provided herein describes a composition comprising a consortium of bacteria that is capable of consuming methane (CH4) and / or fixing nitrogen (N2) at a high rate.

Disclosed herein are methods for promoting healthy neural development in an unborn baby, which include administering to a maternal subject gestating the unborn baby a composition or a bacterial composition. Compositions can include trimethylamine N-oxide (TMAO), 5-aminovalerate (5-AV), imidazole propionate (IP), hippurate (HIP), or a combination thereof, and the bacterial compositions can include bacteria of the order Clostridiales. Also disclosed are methods for conditioning a female subject for bringing about offspring with healthy neural development. Additionally disclosed are methods for reducing adverse effects of antibiotic treatment on an unborn baby in a pregnant subject. Also disclosed are methods for selecting a female subject for conditioning to foster healthy neural development in offspring.

The present invention relates to the use of bacterial compositions having an arginine deiminase activity (inhibition of nitric oxide synthase by conversion of L-arginine to L-citrulline) of 1-1,000 μmol L-citrulline / h / g composition and a sphingomyelinase (ceramide generation) activity of 0.01-1.000 nmoles ceramides / h / g composition in the treatment and / or prophylaxis of airway diseases caused by viruses such as influenza viruses, coronaviruses, as SARS-CoV, MERS-CoV and SARS-CoV-2, avian viruses, respiratory syncytial virus (VRS), rhinoviruses, pneumoviruses, or respiratory failure induced or aggravated by viral infections, angina pectoris, pulmonary heart, respiratory distress, pulmonary edema, neonatal asphyxia, myocardial infarction, heart failure, respiratory failure Pickwick syndrome, pulmonary hypertension, pneumonia or even cystic fibrosis (CF) aggravated by viral infections.

The application discloses a bacterial composition for promoting the growth and saponin accumulation of Panax notoginseng, which is composed of three strains, including Paenarthrobacter nicotinovorans SQ 15, Bacillus velezenis SQ 24 and Pseudomonas nitroreducens SQ 63, which are preserved in the China General Microbiological Culture Collection Center with the preservation numbers of CGMCC No.31366, CGMCC No.31369 and CGMCC No.31367 respectively. The three strains of beneficial bacteria have the functions of resisting diseases and promoting growth, can promote the growth of the tuberous roots of Panax notoginseng, increase the saponin accumulation in the roots of Panax notoginseng, prevent the root rot of Panax notoginseng and improve the quality of Panax notoginseng.

There is provided a synthetic composition including: (a) bacterial consortium including: (i) at least three bacterial species belonging to the genus Bacillus; and (ii) at least three bacterial species belonging to the genus Lacticaseibacillus; and (b) an acceptable carrier, as well as a method of using same, such as for preventing or treating a fungal infection in a plant or a plant part.

This document describes a bacterial composition and its use for controlling, suppressing, and / or preventing infection of tomatoes with the tomato canker fungus (Cmm). The bacterial composition comprises an aqueous mixture of live Bacillus subtilis and live Bacillus pumilus. The bacterial composition can be combined with existing herbicides, insecticides, mycicides, bactericidal agents, and nutrients, including but not limited to copper-containing compounds. Combination with copper mycicides such as Kocide® imparts synergistic efficacy.

Provided herein are biomarkers that are useful in various aspects of treating and preventing complications and side effects associated with a disease or disorder, such as those associated with immune suppression, disruption of the gastrointestinal microbiome, infections (e.g., bloodstream infections), and / or GvHD, for example, in HSCT subjects. In some aspects, the biomarkers provided herein can be used in identifying a subject who is responding to a bacterial composition and / or subjects that are suitable for a treatment with a bacterial composition.

The invention relates to a polynucleotide comprising a lacZ gene (lacZFS) encoding a β-galactosidase characterized by a particular profile regarding its efficiency of hydrolysis of lactose. The invention is also directed to a Streptococcus thermophilus strain comprising a lacZFS allele and bacterial composition thereof, and their use to obtain fermented milk not undergoing post-acidification.