50 results about "Fluxapyroxad" patented technology

The invention relates to a bactericidal composition containing fluxapyroxad and thiediazole copper. The bacterial composition is compounded from fluxapyroxad and thiediazole copper in a binary mode, wherein a mass ratio of fluxapyroxad to thiediazole copper is (1-50) to (50-1); a mass fraction of fluxapyroxad and thiediazole in the preparation is 1%-80%, and the rest of the preparation is auxiliary components which are allowed to use and are acceptable in a pesticide. A dosage form of the bactericidal composition is missible oil, a suspending agent, wettable powder, a water dispersible granule, emulsion in water, microemulsion, a granule and a micro-capsule. The bactericidal composition is mainly used for controlling plant gray mold, peronospora and phytophthora germs.

The present invention relates to a fluxapyroxad intermediate trifluoronitrobiphenyl synthesis method, and belongs to the technical field of organic synthesis, the method comprises the following steps: Step 1: under nitrogen protection, adding 3, 4, 5-bromotrifluorobenzene, o-nitrophenylboronic acid, a catalyst, a promoter, an alkali and a solvent into a reaction flask, and after addition, carrying out a heat preservation reaction; and Step 2: after the reaction is finished, carrying out phase splitting and organic phase concentration to obtain the 3 ', 4', 5 '-trifluoro-2-nitrobiphenyl. Compared with a traditional synthetic method of the trifluoro-nitrobiphenyl, the synthetic method of the trifluoro-nitrobiphenyl has the advantages that the 3, 4, 5-trifluoro-bromobenzene and the o-nitrophenylboronic acid are directly used as raw materials, the production step of preparing the 3, 4, 5-trifluoro-phenylboronic acid from the 3, 4, 5-trifluoro-bromobenzene through a multi-step reaction is avoided, the yield can be effectively improved, the utilization rate of the raw materials is high, and the method is suitable for industrial production. And the o-nitrophenylboronic acid preparation method is simple, the reaction cost can be effectively reduced, the reaction route is shorter, simpler and more efficient, the reaction conditions are mild, and the method has higher industrial application value.

The invention discloses a fluopyram preparation method, which comprises: S1, carrying out a heating reaction on 2-vinyl-3-chloro-5-trifluoromethylpyridine, ammonia water, a catalyst and a solvent, carrying out reduced pressure distillation after the heating reaction to recover the solvent so as to obtain a residue, and adding dichloromethane and triethylamine to the residue so as to obtain a reaction liquid; and S2, dropwise adding o-trifluoromethyl benzoyl chloride into the reaction liquid in an ice bath, then removing the ice bath, stirring at the room temperature, adding water into the reaction liquid obtained in the step S1, extracting an organic layer, drying with anhydrous magnesium sulfate, recovering the solvent under reduced pressure, and performing vacuum drying to obtain the fluopyram. The method has the advantages of high reaction yield, high product purity, recyclable and reusable solvent, simple and mild production process, and suitableness for mass production.

The invention relates to the technical field of pesticides, and discloses a fluopyram compound and a preparation method thereof. The preparation method of the fluopyram compound comprises the following steps: 1) in the presence of a first organic solvent and first alkali, carrying out nucleophilic substitution reaction on a compound with a structure as shown in a formula (1) and a compound with a structure as shown in a formula (2); 2) carrying out a decarboxylation reaction on the nucleophilic substitution reaction product obtained in the step 1) in the presence of a first solvent and a first acid; 3) in the presence of a second solvent and a second acid, the decarboxylation reaction product obtained in the step 2) is subjected to a decyanation reaction to obtain the fluopyram compound, in the formula (1), X represents halogen, and R1 represents-COOC1-6 alkyl; in formula (2), R2 represents an alkyl group having 1-6 carbon atoms. According to the preparation method of the fluopyram compound, the yield is higher, and the operation is more convenient. # imgabs 0 # formula (1) # imgabs 1 # formula (2).

The invention relates to a general synthesis method of an amide compound, and belongs to the technical field of organic synthesis, the synthesis method comprises the following steps: Step 1, adding a carboxylic acid raw material, an amine compound, a catalyst and a solvent into a reaction flask, the amine compound is trifluoro amido biphenyl, dichloro p-fluoro amido biphenyl or p-chloro amido biphenyl, the catalyst is DMAPO, the solvent is methylbenzene, then heating reflux is carried out, heat preservation reaction is carried out with water, and the reaction time is 5-6 h; and Step 2, after the reaction is finished, cooling to 0-5 DEG C, crystallizing, filtering, and drying a filter cake to obtain the amide compound which is fluxapyroxad, bixafen or boscalid. According to the invention, carboxylic acid and amine are directly used as raw materials, under the action of the catalyst DMAPO, toluene reflux condensation with water is carried out to obtain a corresponding amide compound, carboxylic acid does not need to be firstly prepared into carboxylic ester or acyl chloride intermediate, the reaction route is greatly shortened, and the raw material cost is effectively reduced.

The invention relates to a one-pot synthesis method of a fluxapyroxad intermediate 3 ', 4', 5 '-trifluoro-2-nitrobiphenyl, and belongs to the technical field of organic synthesis.The method comprises the following steps that 1, under nitrogen protection, magnesium chips, a catalyst and a solvent are added into a reaction flask, then a mixed solution of 3, 4, 5-trifluorobromobenzene, o-chloronitrobenzene and boric acid ester is dropwise added, a reaction is conducted for 1-2 h, and a reaction solution is obtained; after dropwise adding, carrying out heat-preservation reaction; 2, after the reaction is finished, 10% diluted hydrochloric acid is added for acidification and water washing, after phase splitting, an obtained organic phase is subjected to vacuum concentration, and 3 ', 4', 5 '-trifluoro-2-nitrobiphenyl is obtained. Compared with a traditional synthesis method of the fluxapyroxad intermediate, the synthesis method of the fluxapyroxad intermediate has the advantages that 3, 4, 5-trifluorophenylboronic acid does not need to be prepared firstly, 3, 4, 5-trifluorobromobenzene and o-chloronitrobenzene are directly used as raw materials, the one-pot synthesis method is short in reaction route and high in raw material utilization rate, and the raw material cost can be greatly reduced.

The present invention is directed to stable flumetylsulforim compositions, combinations of fluxapyroxad and rapeseed oil, and to a method for the control and / or prevention of (i) fungal pathogen attack on a plant or (ii) plant and / or soil fungal disease, wherein the method comprises applying the composition or the combination described herein.

The present invention belongs to the field of pesticide sterilization technology and discloses a sterilization composition. The active ingredients of the sterilization composition include active ingredient A, active ingredient B, and active ingredient C. Active ingredient A is fluopyraclostrobin, active ingredient B is prothioconazole, and active ingredient C is difenoconazole. The sterilization composition of the present invention has good sterilization efficacy and significant synergistic effects against various pathogens.

The present invention relates to a method for synthesizing the fluxapyroxad intermediate trifluoronitro - biphenyl, belonging to the technical field of organic synthesis. The method process includes the following: Step1: Under nitrogen protection, add 3,4,5 - trifluorobromobenzene, o - nitrophenylboronic acid, a catalyst, a cocatalyst, a base and a solvent into a reaction flask. After addition, carry out a heat - preservation reaction; Step2: After the reaction is completed, through phase separation, the organic phase is concentrated to obtain 3’,4’,5’ - trifluoro - 2 - nitrobiphenyl. In the present invention, compared with the traditional method for synthesizing trifluoronitro - biphenyl, the method for synthesizing trifluoronitro - biphenyl directly uses 3,4,5 - trifluorobromobenzene and o - nitrophenylboronic acid as raw materials, avoiding the production steps of preparing 3,4,5 - trifluorobenzeneboronic acid from 3,4,5 - trifluorobromobenzene through multiple steps. Moreover, it can effectively improve the yield, has a high raw material utilization rate, and the preparation method of o - nitrophenylboronic acid is simple, which can effectively reduce the reaction cost. The reaction route is shorter, simpler and more efficient, the reaction conditions are mild, and it has high industrial application value.

The invention discloses a mixed suspended seed coating agent for preventing diseases and insect pests in a peanut seedling stage, relates to the technical field of peanut suspended seed coating agents, and aims to solve the technical problems that pungent peculiar smell exists, the insecticidal effect is not comprehensive, the effect of improving soil is not achieved, and rooting and germination of peanuts are not facilitated in the prior art. The mixed suspended seed coating comprises the following components in parts by weight: 10-20 parts of fluopyram, 5-8 parts of a fludioxonil suspending agent, 10-20 parts of difenoconazole, 10-20 parts of trifloxystrobin, 3-5 parts of a plant growth regulator, 3-5 parts of trace elements, 5-10 parts of jatropha curcas biodiesel, 30-45 parts of water, 1-5 parts of an auxiliary agent, 1-3 parts of amino-oligosaccharin, 1-3 parts of lentinan and 1-3 parts of harpin protein. According to the mixed suspended seed coating, 1-3 parts of thiophanate methyl, 1-3 parts of sophocarpidine, 1-3 parts of phoxim, 3-5 parts of herba portulacae, 3-5 parts of tobacco shreds, 3-5 parts of sasangua cake and 3-5 parts of dye are included, the pungent peculiar smell can be reduced, various pests can be effectively killed, and meanwhile the sasangua cake can improve the soil structure.

The application discloses a kind of two-component fungicide containing fluoximide, effective component includes fluoximide and propiconazole, and the weight ratio of fluoximide and propiconazole is 1 :(0.2-3).The application has good control effect on banana leaf spot disease, and is safe to banana, can delay the process of drug resistance of drug resistance;And the combination of aryl phenol polyoxyethylene ether and fatty alcohol polyoxyethylene ether is used as emulsifying agent, and the prepared pesticide microemulsion has good stability and short foaming time.Fluoximide and propiconazole mixed preparation have good synergistic effect, can reduce the amount of drug, delay and control the drug resistance of pathogenic bacteria, and also make the mixed preparation have protection, treatment and internal absorption, realize the purpose of taking long and short, complementary advantages, expand the control spectrum and use range.

The present invention relates to a one-pot synthesis method of the fluxapyroxad intermediate 3',4',5'-trifluoro-2-nitrobiphenyl, belonging to the technical field of organic synthesis. The method process includes the following steps: Step 1: Under nitrogen protection, add magnesium chips, a catalyst and a solvent to a reaction flask, and then dropwise add a mixed solution of 3,4,5-trifluorobromobenzene, o-chloronitrobenzene and borate ester. After the dropping is completed, keep the reaction under heat preservation; Step 2: After the reaction is completed, acidify and wash with 10% dilute hydrochloric acid, and after phase separation, the obtained organic phase is concentrated under reduced pressure to obtain 3',4',5'-trifluoro-2-nitrobiphenyl. In the present invention, compared with the traditional synthesis method of the fluxapyroxad intermediate, the synthesis method of the present fluxapyroxad intermediate does not need to prepare 3,4,5-trifluorophenylboronic acid first, but directly uses 3,4,5-trifluorobromobenzene and o-chloronitrobenzene as raw materials. The "one-pot" synthesis method has a short reaction route, high raw material utilization rate, and can greatly reduce the raw material cost.

The invention relates to a sterilization composition containing fluopyram, in particular to application of the sterilization composition containing fluopyram and iprodione to prevention and treatment of cucumber downy mildew, and the composition is mainly characterized in that the weight ratio of fluopyram to iprodione is 1: 1-1: 12, the composition is prepared into a suspending agent, and the suspending agent is a suspending agent. The dosage of the effective active ingredients is 30-120 g / hectare.

An agrochemical composition comprising component (1) and a mixture of at least two components selected from component (2), component (3) or a combination of component (2) and component (3) wherein component (1) is at least one compound of formula (I) # imgabs0 wherein R1, R2, R3, R4, R5, R6, R7 and n are defined in the specification; component (2) is at least one fungicide selected from the group consisting of: azoxystrobin, metominostrobin, picoxystrobin, trifluroxystrobin, metetropro, benzsovin diflupyr, bixafen, fluindazole, fluxafloxam, infringastatin, difenoconazol, and cyroconazol, and the component (2) is at least one fungicide selected from the group consisting of: azoxystrobin, metominostrobin, picoxystrobin, trifluroxystrobin, metetropro, benzsovin, bixafen, fluindazole, fluxafloxam, fluxafloxam, fluxafloxam, fluxafloxam, and cyroconazol And component (3) comprises at least one fungicide, different from component (1) and component (2), selected from the group consisting of (A) an inhibitor of the biosynthesis of sterols, (B) an inhibitor of the respiratory chain complex I (complex I) or complex II (complex II), (C) an inhibitor of the respiratory chain complex III (complex III), (D) a compound which may have a multi-site action, or (E) an inhibitor of histone deacetylase. The invention also relates to formulations comprising the compositions of the invention and to methods of controlling phytopathogenic fungi of plants using the agrochemical compositions of the invention.

The invention discloses a novel chiral succinate dehydrogenase inhibitor and application thereof, and belongs to the field of pesticide chemistry. The compound shown in the formula (I) is obtained by modifying a fluxapyroxad structure, and an aniline group of fluxapyroxad is mainly replaced by a cyclohexylamine group with a chiral structure. The antibacterial activity of the compound is improved, and the compound can play a better role in preventing and controlling fungal diseases of plants, so that the yield and quality of crops are improved, the application amount of pesticides is reduced, environmental pollution and ecological damage are reduced, and the problems of pesticide resistance and the like are solved. # imgabs0 # is represented by formula (I).

The invention provides application of a bactericidal composition to prevention and treatment of citrus resinosis, and particularly relates to the bactericidal composition with effective active ingredients of fluopyram and oxine-copper, the bactericidal composition is characterized in that the weight ratio of fluopyram to oxine-copper is (1: 1)-(1: 9), and the dosage form of the bactericidal composition is a suspending agent. According to the composition disclosed by the invention, fluopyram and oxine-copper are mixed according to a certain proportion to prepare a suspending agent, the suspending agent has a very good effect on preventing and treating citrus resinosis, and particularly, when the suspending agent is applied in the morbidity period, diseases can be effectively treated, the immunity of citrus can be enhanced, and the outbreak of citrus red mites can be reduced.

The invention relates to a method of cultivating soybean exposed to at least one fungal disease comprising a step of applying to said cultivated soybean an effective treatment with a fungicide composition comprising at least fluxapyroxad in combination with at least two applications of a phytosterol composition comprising at least one phytosterol and at least one sucrose fatty acid ester to increase the yield of said cultivated soybean and / or to reduce the effects of said at least one fungal disease in comparison to soybeans under similar conditions treated only with the organo-chemical fungicide treatment.

The present invention belongs to the technical field of pesticides, and discloses a bactericidal composition containing bronopol and its use. The bactericidal composition comprises active ingredient A and active ingredient B. The active ingredient A is bronopol, and the active ingredient B is selected from any one of fluxapyroxad, isopyrazam or penflufen. The mass ratio of the active ingredient A to the active ingredient B is 1:35 to 35:1. The bactericidal composition of the present invention has high activity against diseases on various crops, has a significant synergistic effect, is superior to single agents in terms of quick-acting property and long-lasting property, reduces the usage amount of pesticides in agricultural production, reduces the pesticide residues in agricultural products, delays the generation of drug resistance of pathogenic bacteria, and is beneficial to the comprehensive management of agricultural diseases.

The application discloses a method for converting diacylated by-product into monoacylated product in the synthesis of fluoxastrobin, and belongs to the field of pesticides and intermediates. The method can effectively recover fluoxastrobin in a crystallization mother liquor and convert diacylated by-product, which is difficult to avoid in the synthesis process, into monoacylated product. The diacylated by-product and fluoxastrobin are close in polarity, and are difficult to remove by a conventional recrystallization method. In the application, the crystallization mother liquor containing the diacylated by-product and fluoxastrobin is dissolved in an organic solvent, a base is quantitatively introduced, the diacylated by-product is converted into monoacylated fluoxastrobin, the reaction solution is concentrated and recrystallized to purify, and the monoacylated product is obtained. In the application, the diacylated by-product is converted into the target product, and another by-product with stronger polarity is generated at the same time, which can be easily separated by recrystallization to obtain the target product with high purity. The process operation is simple, the conditions are mild, the separation yield is high, and the application has important significance for reducing three wastes, reducing cost and improving product quality.

The invention discloses a bactericide containing fluxapyroxad and epoxiconazole, which is prepared from the following raw materials in percentage by weight: 5 to 20 percent of epoxiconazole, 5 to 20 percent of fluxapyroxad, 0.01 to 0.5 percent of defoaming agent and the balance of solvent. The weight ratio of the fluxapyroxad to the epoxiconazole is 1: (1-5), the fluxapyroxad and the epoxiconazole are prepared into the suspension liquid, the prepared pesticide suspension liquid can improve the sterilization and antibacterial capacity of a system and cannot generate cross resistance, and formed pesticide spray is small in particle size and can be used for spraying pesticide. The wetting dispersant adopts the combination of sodium polycarboxylate and alkyl naphthaldehyde condensate, so that the wetting permeability of the liquid medicine can be improved, fog drops are prevented from falling off in the spraying process, the adhesion of the liquid medicine is enhanced, and the deposition amount of the liquid medicine on the surface of a target is increased.

The present invention belongs to the technical field of organic fertilizers, and particularly relates to a black soldier fly manure organic fertilizer. A black soldier fly manure organic fertilizer is composed of the following components in percentage by mass: 35-50% of black soldier fly manure fermentate, 2-10% of insecticidal component, 8-10% of potassium dihydrogen phosphate, 4-6% of magnesium sulfate, 1-7% of sodium lignosulfonate, and bentonite is supplemented to 100%; wherein, the insecticidal component is composed of fluxapyroxad and cyflumetofen or flubendiamide. In the present invention, the black soldier fly manure is mixed with an insecticidal component having a synergistic effect to form a medicament fertilizer, which can not only provide nutrients for plant growth, but also control pests (especially root-knot nematodes) that affect plant growth. Thus, a single fertilization can achieve the dual effects of promoting growth and killing insects, and can further improve the utilization value of black soldier fly manure. In addition, the insecticidal component of the present invention is composed of two components, which can improve the control effect on pests and reduce the risk of drug resistance at the same time.

The application belongs to the technical field of pesticide fungicidal technology, and discloses a fungicidal composition and application thereof, wherein the active ingredient of the fungicidal composition comprises active ingredient A and active ingredient B; the active ingredient A is carmeconazole; the active ingredient B is any one of fluazinam, bifenathi, penthiopyrad and isopyrazam; and the mass ratio of the active ingredient A to the active ingredient B is 1:35-30:1. The fungicidal composition can effectively prevent and control pathogenic bacteria, has a significant synergistic effect, reduces the use amount of pesticides, and reduces environmental pressure.

The application belongs to the technical field of pesticide fungicidal technology, and discloses a fungicidal composition and application thereof. The fungicidal composition comprises active ingredient A and active ingredient B. The active ingredient A is a compound of formula I. The active ingredient B is any one of fluazinam or fluazinamide. The fungicidal composition has good control effect on various plant diseases, slows down the development of pathogenic bacteria resistance, reduces the use dose of pesticides, reduces environmental pollution, and reduces pesticide residues.

The invention relates to the technical field of food safety detection, and discloses a method for detecting five novel pesticide residues in a fruit and vegetable matrix by combining a QuEChERS technology with gas chromatography-triple quadrupole mass spectrometry. According to the method, a QuEChERS technology is combined with a gas chromatography-triple quadrupole mass spectrometry method to detect the content of the diflufenican, the ipfencarbazone, the oxathiazil, the cyclopyridazinate and the pethoxamid in the fruit and vegetable matrix. The method is simple, convenient, rapid and high in accuracy and precision, and provides technical support for daily detection of fruit and vegetable products; comprising 1, sample pretreatment: weighing a proper amount of a fruit and vegetable sample, and treating the fruit and vegetable sample with an extraction solvent, a water removal agent, an extraction salt and a cleaning agent to obtain a to-be-detected sample filter residue, 2, solution preparation: respectively preparing a required standard stock solution, a mixed standard working solution and a blank matrix standard solution, and 3, detecting the to-be-detected sample filter residue or / and the blank matrix standard solution.

The invention provides a composition containing fluopyram, prothioconazole and amino-oligosaccharin. The composition is prepared from the following components in percentage by weight: 1 to 30 percent of fluopyram, 1 to 20 percent of prothioconazole and 0.1 to 5 percent of amino-oligosaccharin. The composition can be prepared into a suspended seed coating agent and a seed treatment suspending agent, and can be used for treating the two diseases, namely the rice bakanae disease and the rice aphelenchoides besseyi.

The invention belongs to the technical field of pesticides, and discloses a bronopol-containing bactericidal composition and application thereof.The bactericidal composition comprises an active ingredient A and an active ingredient B. The active ingredient A is bronopol, and the active ingredient B is selected from any one of pydiflumetofen, isopyrazam or penflufen. The mass ratio of the active component A to the active component B is (1: 35)-(35: 1). The bactericidal composition disclosed by the invention has relatively high activity on diseases of various crops, is remarkable in synergistic effect, is superior to a single agent in fast-acting property and persistent effect, reduces the dosage of agents in agricultural production, reduces pesticide residues of agricultural products, delays the generation of drug resistance of pathogenic bacteria, and is beneficial to comprehensive treatment of agricultural diseases.

This invention relates to a method of controlling, limiting or preventing an infestation of a plant by Oomycetes, which comprises applying to propagation material of said plant, a pesticidal combination comprising a phosphorus-based compound as active ingredient A, and an active ingredient B selected from acibenzolar-S-methyl, fludioxonil, fluxapyroxad, inpyrfluxam, mefentrifluconazole, prothioconazole, sedaxane, triticonazole, oxathiapiprolin, fluoxapiprolin, azoxystrobin, difenoconazole, fluopyram, ipconazole, metyltetraprole, silthiofam, dimethomorph, thiophanate-methyl, natamycin, benzovindiflupyr, pydiflumetofen, picarbutrazox, isocycloseram, cyclobutrifluram, broflanilide, thiamethoxam, imidacloprid, clothianidin, cyantraniliprole, chlorantraniliprole, tetraniliprole, fipronil, and any mixture thereof.

The present disclosure relates to a process for the preparation of fluxapyroxad. The process of the present disclosure provides fluxapyroxad with high purity and in greater yields. The process of the present disclosure is simple, cost effective, environment friendly and employs less toxic and easily available reagents.

The invention relates to application of a prothioconazole-containing composition to prevention and treatment of wheat powdery mildew, in particular to application of a prothioconazole-fluxapyroxad bactericidal composition to prevention and treatment of wheat powdery mildew, which is mainly characterized in that the weight ratio of prothioconazole to fluxapyroxad in the bactericidal composition is (5: 1)-(1: 1); the composition is prepared into a suspending agent.