444 results about "Bromobenzene" patented technology

The invention discloses a method for synthesizing fluorine-containing antiform alkyl cyclohexyl biphenyl single liquid crystal; in the method, bromobenzene and magnesium are selected to carry out Grignard reaction; then the reactants are coupled and hydrolyzed with alkyl cyclohexanone; dehydration, hydrogenation, transformation and iodization are carried out to synthesize alkyl cyclohexyl iodide; the Grignard reaction is carried out on fluorobromobenzene and magnesium, then low temperature coupling is carried out to synthesize p-fluoropheyl boric acid; finally, coupling reaction is carried out to synthesize the target compound; the method of the invention has the characteristics of use of highly active load catalyst, high yield, low production cost, little discharge of three wastes, reduction of generation of isomers and improvement of selectivity and yield of the target compound.

The present invention provides process of preparing pentafluoropheol. Pentafluoro bromobenzene as initial material is first made to produce Grignard reaction to result in Grignard reagent, and the Grignard reagent is then oxidized with peroxide to prepare pentafluoropheol. The process of the present invention has simple technological process, no need of special apparatus, high product yield, high product purity and low production cost.

The invention relates to a specific fluorescent probe for identifying hydrogen sulfide and an application of the probe, belonging to the field of fine chemical engineering. The fluorescent probe is a resorufin derivative. Resorufin sodium salt, potassium carbonate and 2, 4-binitro bromobenzene are mixed in proportion in acetonitrile liquor to be heated, and finally are purified by silica gel chromatography to obtain the fluorescent probe. The fluorescent probe and a corresponding hydrogen sulfide content detection process are not interfered by matrixes and impurities in a biosystem and can be used for quantitative determination of hydrogen sulfide content in various biosystems. The fluorescent probe has high specificity and can be hydrolyzed with hydrogen sulfide after being specifically cyclized to obtain a hydrolysate with broken ether bonds. The probe is low in cost and feasible, can be obtained by chemical synthesis and is simple and feasible in synthetic process. The probe is high in sensitivity, and has good fluorescence emission spectrum characteristics (600-650nm). In the wavelength range, the background fluorescence of a biological sample is weak, so that the probe is suitable for detecting hydrogen sulfide content in cells. Hydrogen sulfide is quantitively detected by drawing a standard curve.

The invention discloses a preparation method of 3, 4, 5-trifluoro bromobenzene. The method comprises the following steps: (1) dispersing 2, 3, 4-trifluoro aniline in a solvent, dropwise adding bromine to carry out a bromination reaction, thus obtaining 2, 3, 4-trifluoro-6-bromaniline through aftertreatment after the reaction is completed; (2) dissolving sodium nitrite in sulfuric acid, dropwise adding the 2, 3, 4-trifluoro-6-bromaniline obtained in the step (1) while stirring to carry out a diazotization reaction, thus obtaining a diazonium salt intermediate; and (3) under the action of hypophosphorous acid and a copper catalyst, carrying out a desamination reaction on the diazonium salt intermediate obtained in the step (2), thus obtaining the 3, 4, 5-trifluoro bromobenzene through aftertreatment after the reaction is completed. The preparation method has the advantages that the 2, 3, 4-trifluoro aniline is adopted as a starting material; the bromination reaction is realized with high selectivity; by-products are reduced; the purity and the yield of the brominated product are increased; the final yield and purity of the 3, 4, 5-trifluoro bromobenzene are high.

The invention relates to a benzothiazoles fluorescent probe for identifying hydrogen sulfide, and the application of the fluorescent probe, belonging to the field of fine chemical industry. The fluorescent probe is 2-(2-hydroxy phenyl) benzothiazole derivatives, and is prepared by the steps of mixing 2-(2-hydroxy phenyl) benzothiazole with potassium carbonate and 2, 4-dinitro bromobenzene in proportion, and finally purifying by a silica gel column chromatography. The fluorescent probe and the corresponding hydrogen sulfide content detection process are not interfered by biological system matrix and impurities and can be used for quantitative measurement of hydrogen sulfide content in various biological systems. The benzothiazoles fluorescent probe is high in specificity, can be hydrolyzed after being specifically cyclized with the hydrogen sulfide, and namely, is hydrolysate of ether cleavage; the benzothiazoles fluorescent probe is cheap and easily available, can be obtained by chemical synthesis, and is simple and practicable in synthetic process; the benzothiazoles fluorescent probe is high in sensitivity, has good fluorescence emission spectrum characteristic (450-500nm), and can be used for quantitative measurement of the hydrogen sulfide by drawing a standard curve.

The invention relates to a polyamide-imide insulating varnish. The polyamide-imide insulating varnish is characterized in that the varnish comprises the following components in parts by weight: 100-120 parts of polyamide-imide solution and 2-5 parts of sepiolite material, wherein the polyamide-imide solution mainly comprises the following components in parts by weight: 20-35 parts of polyamide-imide resin and 20-60 parts of organic solvent; the organic solvent is one or a combination of N-methylpyrrolidone, chlorobenzene, bromobenzene, dichlorobenzene, dibromobenzene, 1-tetralone, fenchone, phorone and isophorone; and the sepiolite material mainly comprises sepiolite. The polyamide-imide insulated enamel wire provided by the invention forms a homogeneous stable system, the surface friction coefficient is below 0.30, and each index meets the International Electrotechnical Commission (IEC) standard requirement; and the polyamide-imide insulating varnish is suitable to be used as the enamel wire insulating varnish for coating the surface of the copper wire.

Disclosed herein are a liquid for a liquid lens and a liquid lens module. The liquid for a liquid lens comprises an electrolyte solution and an insulating solution wherein the electrolyte solution contains H₂O, 1,2-propanediol and LiCl, and the insulating solution is a silicon (Si) oil and optionally contains 1,6-dibromohexane or bromobenzene as an organic additive. The liquid lens module comprises a transparent cover, a case for accommodating an electrolyte solution and an insulating solution, a pair of electrodes for supplying electricity to the electrolyte solution, and an insulating film for covering one of the electrodes in contact with the electrolyte solution wherein the electrolyte solution contains H₂O, 1,2-propanediol and LiCl, and the insulating solution is a silicon (Si) oil. The electrolyte solution and the insulating solution used in the liquid for a liquid lens satisfy the requirements for liquid lenses. In addition, the liquid for a liquid lens ensures superior low- and high-temperature reliability. Therefore, the liquid for a liquid lens is suitable for commercialization.

The invention belongs to the field of medicine synthesis and specifically relates to a preparation method of an anidulafungin side chain intermediate 4'-orthopentyloxy-1,1':4',1'-terphenyl-4-carboxylic acid. The preparation method comprises the following steps: initiating a 1,4-dibromo-benzene material which serves as a starting material to carry out Grignard reagent reaction with magnesium by iodine; then, preparing 1,4-benzene hypoboric acid by virtue of addition and hydrolysis with trimethyl borate; and preparing 4'-orthopentyloxy-1,1':4',1'- terphenyl-ethyl carboxylate by virtue of Suzuki reaction of 1,4-benzene hypoboric acid, 4-pentyloxy bromobenzene and 4-halogenated ethyl benzoate in dioxane-ethanol liquor under catalysis of [1,1'-bis(diphenyl phosphino) ferrocene] palladium dichloride, and then, hydrolyzing to obtain a target product. The preparation method disclosed by the invention can lower process cost, is simple, convenient, safe and reliable to operate, and suitable for industrial production.

The invention discloses a method for extracting lithium isotopes. A chelating agent and a diluent are prepared into an extractive organic phase, and the lithium isotopes are extracted from and separated out of a lithium salt water phase. Hydrophobic ionic liquid with a crown ether structure is adopted as the chelating agent and composed of positive ions and negative ions, wherein positive ions with a structural formula I and/or a structural formula II are adopted as the positive ions. One or more of PF6<->, (SO2CF3)2N<->, (SO2CF2CF3)2N<-> and BF4<-> is/are adopted as the negative ions. One or more of kerosene, octanone, chloroform, dichloromethane, carbon tetrachloride, tetrachloroethylene, nitrobenzene, methylbenzene, dimethylbenzene, diethylbenzene, bromobenzene, anisole, nitromethane, 2-methylcyclohexanone, methylisobutylketone, chlorobenzene, dichlorobenzene, trichlorobenzene and diphenyl ether is/are adopted as the diluent. The method has the advantages of being safe, green, efficient and good in stability and can be used for multi-stage enrichment and separation of the lithium isotopes.

The invention discloses a method for preparing fluoride-bearing phenyloboric acid with a structure shown in (I). The method is characterized in that by taking tetrahydro-2-methylfuran as solvent, fluoride-bearing bromobenzene shown in (II) and magnesium react for 1-8 hours at the temperature of 10-80 DEG C so as to obtain Grignard reagent; and the Grignard reagent and boric acid ester react in thetetrahydro-2-methylfuran for 0.5-8 hours at the temperature of -45-15 DEG C and then carry out hydrolysis in an acid condition, an organic layer is used for solvent recovery so as to obtain a crude product, and the fluoride-bearing phenyloboric acid is obtained after recrystallization of the crude product. The method utilizes the green organic solvent, i.e. tetrahydro-2-methylfuran, to replace tetrahydrofuran, aether and other conventional organic solvents to synthesize the fluoride-bearing phenyloboric acid, the process is simple and safe, and the obtained product realizes high yield and good purity. As the tetrahydro-2-methylfuran has high recovery rate and can be recycled, the production cost of the fluoride-bearing phenyloboric acid is greatly reduced, and great industrialization prospect can be born.

The invention discloses a preparation method of 4-bromocarbazole, which belongs to the field of organic chemical synthesis. The method comprises the following steps: by using o-bromophenylboronic acid as a raw material, a DMSO (dimethylsulfoxide) solvent and o-chloronitrobenzene to generate Suzuki reaction in the presence of combined catalysis of palladium metal and an organic phosphine ligand so as to obtain 2-bromine-2'-nitrobiphenyl; and then synthesizing a product 4-bromocarbazole, from 2-bromine-2'-nitrobiphenyl by using triphenyl phosphite as a reductant. During reaction, side reactions are few, the method is simple to operate and the yield is high. The synthesized 4-bromocarbazole can be used in the fields of organic photoelectric materials, medicines and the like, and is an important intermediate for carbazole photoelectric materials, medicines and presides.

The invention discloses an in situ supported catalyst and a preparation method thereof. The catalyst is used for catalyzing Suzuki reaction. The in site supported catalyst comprises zinc oxide, 2-methylimidazole and palladium ion and is prepared through a mechanochemical method. The catalyst is simple to prepare, can be used for catalyzing bromobenzene (and derivatives thereof) and borophenylic acid (and derivatives thereof) with high activity and high selectivity to perform Suzuki reaction, can be separated from the product simply, and can be reused for times.

The invention discloses functional organosiloxane containing asymmetrical substituted urea and a preparation method thereof. The preparation method comprises the following steps: carrying out reaction between 4, 4'-dibromodiphenylamine and triphosgene to obtain (i) N, N(/i)-di(4-bromo phenyl) carbamyl chloride; and then, carrying out reaction with 3-aminopropyl triethoxysilane to obtain functional organosiloxane, wherein the organosiloxane is the functional organosiloxane containing asymmetrical substituted urea through the verification of infrared spectrum, ultraviolet spectrum, 1H-NMR (1Hydrogen-Nuclear Magnetic Resonance) and 13C-NMR. The structure of the compound contains a plurality of functional groups such as siloxane, amide, urea groups and bromoaryl. The functional organosiloxane has a potential application value on the respects of molecular imprinting recognition materials, structural flame retardant materials, rare earth light emitting materials, white carbon black and the like. The functional organosiloxane disclosed by the invention is reasonable in synthetic line, mild in condition, easy to operate, low in cost of raw materials and high in product yield.

The invention provides a degradation strain for eliminating residual bromoxynil, belonging to the field of biological high technology. The adopted bacterial strain is a gram staining reaction negative strain MXX-04 which is identified to be paracoccussp. The main biological properties are G-, short rod shape, no spores, no motility and positive oxidase and catalase. The strain provided by the invention can grow by taking bromoxynil as a unique nitrogen source and mineralize the bromoxynil. Under the condition of a shake flask in a laboratory, the strain can degrade 95.3% of 100mg/L bromoxynil within 24 hours, thus the problem that bromoxynil is hard to degrade biologically in the environment is solved.

The invention discloses a method for synthesizing phenyl-containing organosilicon monomers. The method comprises the steps of performing one-step Grignard reaction on raw materials including methyltrimethoxy silane, magnesium and benzene halide: performing activation initiation reaction in the presence of a catalytic initiator under the condition that a solvent is added or not added, heating, continuously reacting, filtering and distilling to obtain methyl phenyl dimethoxy silane and methyl diphenyl methoxy silane. According to the method, the novel and cheap raw materials including methyltrimethoxy silane, magnesium and chlorobenzene (or bromobenzene) are used, and the raw materials react at a certain temperature by adopting the one-step Grignard method and using iodine as the catalytic initiator, are heated and then continuously react to obtain methyl phenyl dimethoxy silane and methyl diphenyl methoxy silane, thus solving the problem that the preparation of methyl phenyl dimethoxy silane with the one-step Grignard method is not realized at present and the problems of low yield, high production cost and the like when methyl triethoxysilane is used as a raw material, and meeting the requirements of modernized industrial production for high yield and low energy consumption.

A new eco-friendly process is described in the present invention for the preparation of bromobenzene through substitution of one of the C—H proton of benzene ring with a highly reactive hypobromous acid generated in situ, said process comprises the steps of activating a water soluble, easy to handle, brominating reagent with a mineral acid at elevated temperature and atmospheric pressure to generate active bromine species which in turn reacts with benzene.

The invention relates to a triphenylamine containing isoindigo polymer, a preparation method of the triphenylamine containing isoindigo polymer, and an application of the triphenylamine containing isoindigo polymer to electrochromism, and relates to an isoindigo polymer and a preparation method and an application of the isoindigo polymer. The invention aims at solving the problem of relatively narrow application range of isoindigo caused by the low solubleness of the isoindigo in an organic solvent. The structural formula of the triphenylamine containing isoindigo polymer is shown in the description, wherein n in the formula is a positive integer. The preparation method is as follows: 1, synthesizing N<1>,N<1>-bi(4-bromobenzene group)-N<4>,N<4>-diphenylbenzene-1,4-diamine monomer; 2, preparing an isoindigo derivative; 3, preparing the triphenylamine containing isoindigo polymer. The invention discloses the application of the triphenylamine containing isoindigo polymer to electrochromism as an electrochromic layer in an electrochromic device. The polymer has the electrochromic property and the memory property, can be applied to the electrochromism field, and is excellent in explosive detection and photoelectric detection. The triphenylamine containing isoindigo polymer is suitable for preparing the isoindigo polymer and the application of the isoindigo polymer.

The invention designs a polyamide imide insulating paint, which is characterized by comprising 100-120 parts by weight of polyamide imide solution and 2-5 parts by weight of montmorillonite material, wherein the polyamide imide solution mainly comprises the following components in parts by weight: 20-35 parts of polyamide imide resin and 20-60 parts of organic solvent, and the organic solvent is one or more of N-methyl pyrrolidone, chlorobenzene, bromobenzene, dichlorobenzene, dibromobenzene,1-tetralone, fenchone, phorone and isophorone; and the montmorillonite material mainly comprises montmorillonite. According to the invention, the polyamide imide insulating enamelled wire forms a homogeneous and stable system, has the surface friction coefficient below 0.30 and indexes satisfying standard requirements of international electrotechnical commission (IEC), and is particularly suitable to be used as enamelled wire insulating paint for coating the surface of a copper wire.

The invention relates to coronene compound containing thioether in lateral chain and the preparation method thereof. The structural formula of the compound is shown in the descriptiopn: R refers to alkyl. In the method, ring trimerization- ferric trichloride coronene method, namely 2- (4'- bromophenyl) ethanol is taken as raw material, through hydroxyl bromo, thioether is formed, palladium-catalyzed is selected for direct coupled reaction, so as to obtain diphenylacetypene ramification, under the catalysis of cobalt carbonyl, corresponding hexaphenylbenzene is produced by trimerization cyclization. Anhydrous ferric trichloride is oxidized in methylene dichloride and nitromethane, then reduction is performed by using iodine and sodium borohydride system, and after drying, THF (tetrahydrofuran) is used for recrystal. The synthetic method provided by the invention is simple, is high in yield, and can be extensively used in organic LBD, field-effect tubes and solar batteries.

The invention discloses a production technology for synthesizing bromoxynil, and relates to the technical field of chemical industry. Cyanophenol is subjected to bromination reaction to obtain bromoxynil as a raw material after being synthesized. The production technology has the beneficial effects that the technology is simple and convenient to prepare, environment-friendly, free of pollution, available in raw material, less in equipment investment, high in purity, convenient to operate, good in use effect of prepared bromoxynil, and safe and reliable.

The invention discloses a pure organic D-pi-A type photosensitive dye as well as a preparation method and application thereof. The photosensitive dye is a triphenyl pyrrole D-pi-A type photosensitive dye with 1, 2, 5-triphenyl pyrrole as an electron donor group, styrene as an electron transport chain and cyanoacetic acid as an electron withdrawing group. The preparation method comprises the following steps: under the protection of argon, adding p-formylphenyl styrene, 1-(p-bromophenyl)-2, 5-diphenyl pyrrole, palladium acetate, tetrabutyl ammonium bromide and tri (o-methyl phenyl) phosphorus into a mixed solution of N, N'-dimethylformamide and trimethylamine to prepare 4-(4-(2, 5-diphenyl pyrrole) styryl) benzaldehyde, serving as an intermediate, and then preparing the pure organic D-pi-A type photosensitive dye by virtue of the intermediate. The pure organic D-pi-A type photosensitive dye is simple in synthesis route, low in cost, high in molar extinction coefficient serving as a dye-sensitizer for preparing a solar cell, difficult in desorption and beneficial to prolonging the whole service life of the battery.

The invention relates to a caliper type chromium complex and a preparation method and application thereof, and belongs to the technical field of catalysts. The caliper type chromium complex is a [NCN]-ligand-based caliper type chromium complex. The preparation method comprises the following steps of: adding hexane solution of butyl lithium into tetrahydrofuran solution of a ligand dropwise for reaction; adding a tetrahydrofuran adduct of chromium trichloride or chromium dichloride; and heating the mixture to room temperature naturally and reacting to obtain the caliper type chromium complex. The ligand can be 2,6-bis(N-2,6- phenyl)imido bromobenzene. The caliper type chromium complex, alkyl aluminum and organic boron salt serving as catalysts are used for catalyzing selective polymerization of isoprene or butadiene. The caliper type chromium complex has high stability and is convenient to prepare; the catalytic system can be used for selectively catalyzing polymerization of the isoprene or the butadiene, and has low using amount of a cocatalyst, high polymerization speed, high conversion rate and high anti-1,4 selectivity; and the caliper type chromium complex can be applied actually by replacing natural trans-1,4 rubber.