32 results about "Aromatic ketone" patented technology

The invention relates to environment-friendly hydrophobic ink and a preparation method thereof, and belongs to the technical field of water-based ink. A copolymerization modifier capable of being combined in a water-based polyacrylate emulsion in an initiation polymerization mode in the stage of preparing the modified water-based polyacrylate emulsion is prepared, and an o-hydroxy aromatic ketone structure in the copolymerization modifier can endow water-based ink with lasting ultraviolet absorption performance; the trifluoromethyl structure can reduce the surface energy of the water-based ink, and the benzimidazole ring structure can form stable coordinate bonds with metal ions, so that the bonding performance of the water-based ink and a metal substrate is enhanced; when the copolymerization modifier is used for modifying the water-based polyacrylate emulsion, the long-term performance, the hydrophobic and oil-resistant performance and the adhesion performance on the surface of a metal base material of the finished water-based ink can be effectively improved.

The invention discloses an aromatic ketone two-photon initiator, a preparation method, a composition and application, and relates to the technical field of photoinitiators, the two-photon initiator releases alkaline species through photoinduced decarboxylation under near-infrared femtosecond laser irradiation and catalyzes anion two-photon polymerization reaction, efficient two-photon 3D printing is achieved, and the aromatic ketone two-photon initiator has the advantages of high-efficiency two-photon 3D printing, high-efficiency two-photon 3D printing and high-efficiency two-photon 3D printing. The problems of large polymerization volume shrinkage, harsh working conditions and corrosion of acidic species generated in the curing process to a metal substrate in the current free radical two-photon polymerization and cationic two-photon polymerization are solved; the method shows huge application potential in the fields of high-density optical information storage, micro-nano optical device processing, biological scaffold construction and the like.

The invention discloses a selective modification method of carbon-terminal protected glycine and nitrogen-terminal glycine polypeptide and application of the selective modification method. The preparation method comprises the following steps: reacting carbon-terminal-protected glycine or nitrogen-terminal glycine polypeptide with a specific aromatic ketone compound, taking the nitrogen terminal of glycine as a modification site, and carrying out heating reaction to prepare a nitrogen-containing aromatic heterocyclic ring, so as to finish selective modification of glycine. According to the method provided by the invention, the modification yield of the carbon-terminal-protected glycine is remarkably improved, the method is simple, the reaction time is short, the substrate dosage is low, the selectivity on the glycine is high, interference of amino acids such as lysine and histidine can be avoided, the problems that ortho-amino acids have relatively strong interference on modification, the chemical selectivity is poor and the conversion rate is low are solved, and the method is suitable for industrial production. And more methods are provided for improving the bioavailability of polypeptide drugs, developing new targeted drugs and marking polypeptide.

The present invention provides a composition for forming a bottom spin-coated carbon coating and a bottom spin-coated carbon coating. The composition for forming a bottom spin-coated carbon coating comprises a polymer, and the polymer is a polymer formed by the polymerization reaction of a compound represented by formula A with an aromatic aldehyde or an aromatic ketone: #imgabs0# In formula A, R1 are the same or different and are independently selected from a hydroxyl group, an alkoxy group, an alkyl group, an alkenyl group, -CH(O-alkyl)-O-alkyl, -C(=O)-alkyl or a glycidyl group; R2 are the same or different and are independently selected from a hydrogen atom, an alkyl group, an alkenyl group or an aryl group; k are the same or different and are independently 0 or 1, and at least one hydroxyl group is contained on the four phenyl groups attached with -(R1) k and -OR2 located at the periphery of the compound represented by formula A. The bottom spin-coated carbon coating has high thermal stability, good etching resistance to a fluorocarbon etching gas and excellent filling performance.

The present invention discloses a meso-diaminopimelate dehydrogenase mutant of Proteus vulgaris and its application, belonging to the technical field of bioengineering. The present invention constructs a PvDAPDH mutant, which, compared with the wild enzyme, can catalyze the synthesis of D-amino acids from a variety of aromatic α-ketoacids, and the stereoselectivity can reach 95%. The triple mutant W121I / H227I / R181S of pvDAPDH constructed in the present invention shows good compatibility with different large-volume aromatic α-ketoacid substrates, can simultaneously catalyze the conversion of most aromatic α-ketoacid substrates into D-amino acids, shows high catalytic activity towards 2-oxo-4-phenylbutyric acid, and the yield of the product D-homophenylalanine reaches 2.1 g / L. The present invention effectively expands the toolbox for the biosynthesis of aromatic D-amino acids.

The present invention provides an oral composition that suppresses off-flavors derived from ornithine.　Provided is an oral composition containing the following components (A) and (B): (A) 15 mass% to less than 30 mass% of ornithine; and (B) an aromatic ketone. The mass ratio [(B) / (A)] of component (A) and component (B) is 1.7×10-8 to 1.0×10-4.

The invention discloses a mutant of aromatic dioxygenase CpuADO and application of the mutant. The amino acid sequence of the mutant of the aromatic dioxygenase CpuADO is as shown in SEQ ID NO: 2 or SEQ ID NO: 3. The aromatic dioxygenase CpuADO is found to have broad-spectrum substrate conversion capacity and can catalyze various lignin monomer derived aromatic olefin substrates to generate corresponding aromatic aldehyde or aromatic ketone products, and the catalytic efficiency of two mutants obtained after site-directed mutagenesis of the aromatic dioxygenase CpuADO is further improved; the problems that existing aromatic dioxygenase is poor in adaptability to lignin monomer derived aromatic olefin substrates, narrow in substrate spectrum and low in catalytic efficiency are solved, high-valued utilization of multiple types of lignin monomer derived aromatic olefins is facilitated, and an efficient novel enzyme tool is provided for green biological oxidation conversion of lignin monomer derived aromatic compounds.

COMPOSITION FOR CARE OF KERATINOUS MATERIALS AND MASK COMPRISING SAME The present invention relates to a composition, preferably for care of keratinous materials, comprising: (i) at least one non-ionic polysaccharide chosen from homopolymers of mannose, copolymers of mannose and glucose, copolymers of mannose and galactose, and a combination thereof; (ii) at least one ionic polysaccharide chosen from xanthan gum, carrageenan, gellan gum and a combination thereof;and (iii) at least one preservative selected from chlorophenyl glyceryl ethers, aromatic ketone compounds represented by the following chemical formula (I), and a combination thereof, (I) wherein R5, R6 and R7, each independently, represent a hydrogen atom, a hydroxyl group, a C1-C6 alkyl group or a C1-C6 alkoxy group, provided that at least one of R5, R6 and R7 represents a hydroxyl group, and R represents a C1-C6 alkyl group or an aryl group, wherein the weight ratio of the at least one non-ionic polysaccharide to the at least one ionic polysaccharide is at least 1:5. The present invention also relates to a mask comprising said composition and to a non-therapeutic process for caring for keratinous materials. Figure for abstract: none;

This invention discloses a direct repair and regeneration method for waste lithium iron phosphate cathodes based on a two-electron lithiation reagent, comprising the following steps: (1) disassembling the recycled waste lithium iron phosphate battery after complete discharge, separating and collecting the cathode active material; (2) adding an aromatic ketone dilithium reagent to the cathode active material, stirring and reacting for 1-4 hours, then centrifuging, washing, and drying to obtain a lithified regenerated lithium iron phosphate cathode; wherein: the molar ratio of lithium in the aromatic ketone dilithium reagent to the molar ratio of lithium missing in the cathode active material is ≥1; the aromatic ketone dilithium reagent is composed of aromatic ketone dilithium and an organic solvent; the molar ratio of aromatic ketone molecules to lithium in the aromatic ketone dilithium is 1:2. This invention can achieve twice the lithiation efficiency with the same amount of aromatic chemical reagent consumption, which is beneficial to reducing the material input in the repair and regeneration process. Moreover, the electrochemical performance of the regenerated layered lithium iron phosphate cathode material obtained by this invention is comparable to that of commercial lithium iron phosphate cathodes.

The application discloses a kind of offsite aromatic ketone substituted heptamethine cyanine dyes and its synthesis method and application.The offsite aromatic ketone substituted heptamethine cyanine dye is substituted by heptamethine cyanine dye methine chain, changes the electronic cloud arrangement of cyanine dye, so that the absorption and emission wavelength of dye all have blue shift, has good intersystem crossing ability, can quickly pass through cell membrane, can be concentrated in cell mitochondria, can detect physiological process using the change of cell mitochondria, and can produce a large amount of active oxygen after illumination, cause cell death, realize the purpose of photodynamic therapy.The application can be applied to the field of photocatalysis, as near-infrared region luminescent material, biological marker probe, photodynamic therapy, water photolysis hydrogen production and the field of biological sensing.

The present invention discloses a method for selective modification of carbon-terminal protected glycine and nitrogen-terminal glycine polypeptides and their applications. The present invention reacts carbon-terminal protected glycine or nitrogen-terminal glycine polypeptides with specific aromatic ketone compounds, uses the nitrogen end of glycine as the modification site, and prepares nitrogen-containing aromatic heterocycles by heating reaction to complete the selective modification of glycine. The method provided by the present invention significantly improves the modification yield of carbon-terminal protected glycine. The method is simple, has a short reaction time, a low substrate dosage, high selectivity for glycine, can avoid interference from amino acids such as lysine and histidine, and solves the problems of strong interference of adjacent amino acids on modification, poor chemical selectivity, and low conversion rate. It provides more methods for improving the bioavailability of polypeptide drugs, developing new targeted drugs, and polypeptide labeling.

This invention discloses a self-lubricating polyaryletherketone containing a long-chain fluorinated end-capping agent, its preparation method, and its application. The long-chain fluorinated end-capping agent has the structure shown in general formula I, where R is C4~C6. 10 The end-capping agent is a straight-chain or branched perfluoroalkyl group; the end-capping agent is prepared by a substitution reaction of a fluoroalkyl compound and a hydroxyl-containing aromatic ketone compound dissolved in a polar solvent under alkaline conditions. This invention utilizes the end-capping agent to prepare polyaryletherketones with superhydrophobic surfaces and excellent self-lubricating properties through a one-step polycondensation process. This material has a simple preparation process, readily available raw materials, and low cost, combining high performance and economy. The polyaryletherketone has broad application prospects in aerospace, automotive manufacturing, and electronics and electrical fields.

The application discloses a kind of palladium catalytic preparation 2-fluoro-1,2-diphenyl ethanone compound and its product, belong to organic synthesis technical field, the compound structure is as shown in formula I, its preparation method includes the following steps: (1) palladium catalyst, ligand, base and solvent are mixed uniformly, then join fluorine-containing block and bromoaromatic hydrocarbon are stirred, after reaction, quenching by water, again after extraction, washing, liquid separation, drying, remove solvent, obtain crude product;(2) the crude product is separated and purified by column chromatography, to obtain the 2-fluoro-1,2-diphenyl ethanone compound.The application also discloses the 2-fluoro-1,2-diphenyl ethanone compound prepared by the above preparation method.The application is constructed fluorine-containing aromatic ketone by fluorine-containing block, without directly using fluorination reagent, easy to operate, high yield;And, the application is suitable for a variety of bromoaromatic hydrocarbon substrates, and the universality is wide.

The invention discloses a preparation method of an amido ketone photoinitiator, in the preparation method of an alpha-amido ketone compound, naphthalene is used as a raw material, the cost of the raw material is reduced, the yield of the preparation method is high and can reach 80% or above, and the purity of the alpha-amido ketone compound can reach 95% or above. According to the preparation method of the amido ketone photoinitiator, cheap and easily available industrial-grade raw materials are used as a starting point breakthrough, naphthalene is used as a key group, and alpha-amido aromatic ketone is prepared through easy-to-operate technological processes such as Friedel-Crafts reaction, halogenation, substitution and rearrangement, so that the photoinitiation efficiency is improved; the prepared compound is an environment-friendly, non-toxic and efficient photoinitiator, the problems that volatile toxic small-molecule organic compounds escape in the photocuring process, or irritant and unpleasant smells are generated, or physiological toxicity is caused by compound migration, and the like are solved; the method has a good promotion effect on popularization and application in the field of ultraviolet radiation photocuring.

The invention discloses a preparation method of a divinyl aromatic compound, which belongs to the technical field of thermoplastic resin monomers, and comprises an aromatic ketone compound preparation stage, an aromatic diol preparation stage and a divinyl aromatic compound preparation stage. The method comprises the following steps: generating an aromatic acyl compound from acyl chloride under the action of a catalyst, reacting under the action of a hydrogenation catalyst to generate aromatic diol, and finally dehydrating and eliminating under the action of a dehydration catalyst to generate the divinyl aromatic compound. According to the invention, the aromatic alkane compound is used as a raw material and is prepared through Friedel-Crafts, hydrogenation and dehydration, the preparation process does not need high-temperature and high-pressure operation, the process is simple, the equipment requirement is low, the investment is small, and the production cost is greatly reduced.

KERATINOUS MATERIAL CARE COMPOSITION AND MASK COMPRISING THEREOF The present invention relates to a composition, preferably for the care of keratinous materials, comprising: (i) at least one non-ionic polysaccharide selected from mannose homopolymers, mannose and glucose copolymers, mannose and galactose copolymers, and a combination thereof; (ii) at least one ionic polysaccharide selected from xanthan gum, carrageenan, gellan gum, and a combination thereof;and (iii) at least one preservative selected from chlorophenyl glyceryl ethers, aromatic ketone compounds represented by the following chemical formula (I), and a combination thereof, (I) wherein R5, R6, and R7, each independently, represent a hydrogen atom, a hydroxyl group, a C1-C6 alkyl group, or a C1-C6 alkoxy group, provided that at least one of R5, R6, and R7 represents a hydroxyl group, and R represents a C1-C6 alkyl group or an aryl group, wherein the weight ratio of the at least one nonionic polysaccharide to the at least one ionic polysaccharide is at least 1:5. The present invention also relates to a mask comprising said composition and a non-therapeutic process for the treatment of keratinous materials. Figure for abstract: none;

In one embodiment, the present invention provides a cleaning method that reduces the impact on substrates and exhibits excellent resin mask removability. In one embodiment, the present invention relates to a cleaning method comprising the step of removing the resin mask from an object to be cleaned, to which the resin mask is attached, using a cleaning composition. The cleaning composition comprises an alkaline agent (component A), an organic solvent (component B), a chelating agent (component C), and water (component D), wherein component B is at least one solvent selected from glycol ethers and aromatic ketones, and component C is a compound having two or more acid groups selected from at least one of carboxyl groups and phosphonic acid groups. The content of component B in the cleaning composition during use is from 1% to 12% by mass, and the content of component D in the cleaning composition during use is from 65% to 95% by mass. The object to be cleaned has undergone a step of performing at least one of soldering and plating using the resin mask.

The present invention relates to a two-phase composition comprising an oil phase comprising (a) at least one oil, and an aqueous phase comprising: (b) at least one aromatic ketone compound represented by formula (I); (c) at least one polyglyceryl fatty acid ester; and (d) water. The composition according to the present invention has two visually distinct phases when not being mixed. However, the composition according to the present invention can be transformed into a single phase composition when being mixed. The single phase composition, such as an emulsion, can provide good cosmetic effects such as good make-up removability, without discomfort. The single phase composition can return to a two-phase composition with a clean interface between the two re-formed phases.

The utility model relates to the technical field of aromatic ketone compound separation discloses a kind of aromatic ketone compound separation is with coupling rectifying column device, including tank body, the inside of tank body is fixed with one tray, and the top and bottom of the tray are slidably provided with another tray, by setting multiple trays and its adjustable spacing structure, so that device meets industrial separation demand, with spacing adjustment function under experimental condition simultaneously;Combining the rotary scraper system driven by top first servo motor, three scrapers can remove residue on the top of tray in real time, to avoid the separation efficiency reduction caused by aromatic ketone coking blockage;In addition, bidirectional threaded rod cooperates with sliding block structure, can be adjusted up and down under the premise of keeping the stability of tray, cooperate the scraper of spring support, realize the surface of the tray after automatic fitting adjustment, to improve the adaptability, stability and equipment service life of rectification process.

This invention belongs to the field of metal-organic complex synthetic chemistry, specifically relating to an oxazoline-type chiral N,P ligand represented by formula (I), its preparation method, and application. The oxazoline-type chiral N,P ligand represented by formula (I) can be used to prepare an oxazoline-type chiral N,P ligand manganese complex. The resulting manganese complex has a simple structure and is easy to synthesize. It can also be used to catalyze the asymmetric hydrogenation of aromatic ketone compounds under mild reaction conditions, broadening the application range of the manganese complex. #imgabs0#

The invention discloses a nickel oxide doped manganese dioxide catalyst and a preparation method and application thereof.The catalyst is formed by in-situ growth of nickel oxide doped manganese dioxide on a carbon felt substrate through a solvothermal method. An aromatic compound as a reaction substrate is dissolved in an acidic solution as an anode reaction solution. A counter electrode is used in the cathode chamber, an acidic solution is used as a cathode reaction solution, and after the reaction is finished, aromatic aldehyde or aromatic ketone can be prepared through a post-treatment process. The catalyst has a high surface area and a porous structure, the specific surface area of an electrode is increased, a large number of reaction sites and active sites are provided for oxidation of a substrate, in addition, manganese dioxide provides more active sites due to doping of nickel oxide, formation of an intermediate is promoted, meanwhile, desorption of a product aromatic aldehyde is also promoted, and the catalytic activity of the catalyst is improved. Aromatic acid formed by excessive oxidation is prevented, and the nanorod-shaped three-dimensional structure of the catalyst is beneficial to mass transfer.

The invention provides a protective agent for preventing pesticide poisoning of bees and application of the protective agent in scientific use of pesticides, and belongs to the field of scientific use of pesticides. The protective agent comprises a core component, an organic solvent, an emulsifier, a dispersant and an antioxidant, wherein the core component comprises one or more of an aromatic ketone compound, an alicyclic ketone compound and a fatty straight-chain ketone compound. The protective agent can regulate and control behaviors of bees, interfere smell of collection bees in a pesticide exposure scene, repel flower visiting behaviors of the bees, reduce the pesticide exposure level of the collection bees, and further reduce contact between bee colonies and pesticides. The protective agent can be used as a pesticide partner and can be directly mixed with an existing pesticide product, a core component of the protective agent can be added as an active component during production of a pesticide preparation, and by preventing bees from leaving a pesticide application site and avoiding poisoning, scientific use of the pesticide is facilitated, toxicity to non-target biological bees is prevented, healthy breeding of the bees is facilitated, and the protective agent has a wide application prospect. And poisoning caused by unscientific use of pesticides is prevented.

This invention belongs to the field of organic electrochemical synthesis and relates to a method for preparing aromatic ketone compounds by continuous flow electrochemical microchannel oxidation of alkyl aromatic hydrocarbons. Alkyl aromatic compound I is mixed with an electrolyte, water, and a solvent to obtain a mixture. The mixture is then pumped into a continuous flow electrochemical microchannel reactor of an electrochemical microchannel reaction apparatus to carry out an electrochemical reaction, yielding aromatic ketone compound II. This invention utilizes green electrochemical electrons as the oxidant, eliminating the need for additional metal or non-metal catalysts and widely used oxidants (such as O3, KMnO4, etc.). The reaction system is neutral, the process is simple, and the amount of post-treatment wastewater is minimal.

The present invention provides a novel method for preparing aromatic ketone compounds and intermediates. The method avoids the use of toxic and harmful reagents in the prior art, has mild reaction conditions, is less corrosive to equipment, has wide applicability, does not require special equipment, and is suitable for industrial production.

The invention discloses a special high-molecular material emulsion and a preparation method and application thereof.The special high-molecular material is prepared from fluorine-containing arone monomers, bisphenol compounds and carboxylic acid functional monomers through nucleophilic polycondensation and post-functionalization, the surface of the high-molecular material contains a large number of carboxyl groups and hydroxyl groups, and the special high-molecular material emulsion has the advantages of being high in strength, good in mechanical property and the like. The coating has the characteristics of high temperature resistance, strong carbon fiber material adsorption and infiltration capability, long storage time, high coating hardness and pencil hardness, excellent salt spray resistance and the like, and can be widely applied to the fields of high-temperature-resistant and corrosion-resistant coatings, carbon fiber composite materials and the like; compared with a traditional sulfonation process, the method has more excellent environmental protection performance, belongs to the field of environment-friendly special polymer materials, and has a wide application prospect.

The present invention provides: a compound represented by general formula (1); a photoacid generator and an acid-reactive composition which contain the compound; and an acid generation method using the compound.　In formula (1), Ar11 to Ar13 each represent an aromatic hydrocarbon ring group having a specific substituent; R13 represents a condensed polycyclic aromatic hydrocarbon ring group or a condensed polycyclic aromatic heterocyclic group which may have a specific substituent, a group having an aromatic ketone skeleton, or a group having a conjugated bonding group with an aromatic hydrocarbon ring group or the like; R11 and R12 each represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; Z11 represents an oxygen atom or the like; m1 and p1 are each 0 or 1 (however, m1 is 0 in cases where n1 is 0); n1 is an integer of 0-4; X11 represents a boron atom or the like; and Y11 represents an organic onium cation. However, in cases where R13 is a specific group such as a condensed polycyclic aromatic heterocyclic group and the hetero atom is a bond to Z11, forms wherein m1 = n1 = 0 and forms wherein m1 = 1 are excluded.

A composition, preferably used for caring keratin materials, comprises (i) at least one nonionic polysaccharide selected from homopolymers of mannose, copolymers of mannose and glucose, copolymers of mannose and galactose, and combinations thereof; (ii) at least one ionic polysaccharide selected from xanthan gum, carrageenan, gellan gum, and combinations thereof; and (iii) at least one preservative selected from chlorophenylglycerol ether, aromatic ketone compounds, and combinations thereof, wherein the weight ratio of at least one nonionic polysaccharide to at least one ionic polysaccharide is at least 1:5. The above composition can be used in non-therapeutic methods for caring keratin materials.

The present invention provides an oral composition that suppresses acrid flavors derived from ornithine.　Provided is an oral composition containing the following components (A) and (B): (A) 30-80 mass% of ornithine; and (B) an aromatic ketone. The mass ratio [(B) / (A)] of component (A) and component (B) is 1.7×10-8 to 1.0×10-4.

The application discloses a mutant of aromatic dioxygenase CpuADO and application thereof, and the amino acid sequence of the mutant of the aromatic dioxygenase CpuADO is shown in SEQ ID NO:2 or SEQ ID NO:3. It is found by the application that the aromatic dioxygenase CpuADO has wide-spectrum substrate conversion capacity, can catalyze various lignin monomer derived aromatic olefin substrates to generate corresponding aromatic aldehyde or aromatic ketone products, and the catalytic efficiency of two mutants obtained after site-directed mutagenesis of the aromatic dioxygenase CpuADO is further improved. The problems of poor adaptability, narrow substrate spectrum and low catalytic efficiency of existing aromatic dioxygenases to lignin monomer derived aromatic olefin substrates are solved, the high-value utilization of various types of lignin monomer derived aromatic olefins is facilitated, and an efficient new enzyme tool is provided for green biological oxidation and conversion of lignin monomer derived aromatic compounds.

The invention belongs to the technical field of anion exchange membranes, and discloses an ordered block type polyacylated aryl piperidine membrane as well as a preparation method and application thereof. The preparation method comprises the following steps: acylating part of p-terphenyl by adopting paraphthaloyl chloride to obtain an aromatic ketone block prepolymer which is arranged in order, then adding N-methyl-4-piperidone for copolymerization, then performing quaternization by using methyl iodide, and casting a membrane to obtain the block type polyacylated aryl piperidine membrane which is stacked in order locally. Rigid arone block limited crystals in the ordered block type polyacylated aryl piperidine membrane disclosed by the invention can strengthen hydrophilic and hydrophobic microphase separation, and can broaden and provide partially ordered limited nano channels, so that the chloride ion conductivity of the membrane is improved; and the highly-oriented rigid nano-channel skeleton cooperates with the size effect, so that permeation of active substances is blocked, the selectivity of the membrane is greatly improved, and the performance is excellent when the membrane is applied to the neutral organic flow battery.