The invention discloses a preparation method of nanometer zinc oxide which takes shell powder as a carrier, and in particular relates to a reproducible porous nanometer zinc oxide powder which takes the shell powder as the carrier and the preparation method thereof. In the preparation method, zinc oxide is loaded by impregnation on the shell powder carrier; firstly, zinc salt solution with appropriate concentration is prepared, and then an activated shell powder carrier is impregnated in the zinc salt solution by certain proportion, and then the obtained solution is stirred and stayed for a certain time, and treated by low temperature and abstersion pretreatment and finally roasted at high temperature, so the nanometer zinc oxide forms high-strength bond with the shell powder and promotes the catalytic activity of the nanometer zinc oxide at the same time. Impregnation can be conducted for a plurality of times to increase load. The nanometer ZnO is characterized by small particle size, good compatibility with materials, high catalytic efficiency, good stability, good regenerability, and the like, and can be applied to the fields of plastics, rubbers, fibers, coatings, home appliances, paints, ceramics, water and environment treatment, pharmaceutical and hygienic articles, etc. In terms of sources of raw materials and production technology, the preparation method not only reduces the production cost of nanometer ZnO catalyst but also is helpful for disposal of the increasingly serious environmental problems, thus bearing great environmental protection significance.