88 results about "Catalytic function" patented technology

The invention discloses a fresh plant directed biotransformation method based on endogenous enzyme activation and a product and application thereof. The core of the preparation method is as follows: fresh plants (tuberous roots, stems or fruits) which are harvested in a ripe state and have metabolism in a dormant state (the respiration rate is lower than 5 mg CO / kg.h) are taken as raw materials, the raw materials are treated in an environment with the specific pressure being 0.02-0.20 MPa, the temperature being 70-121 DEG C and the humidity being 50-95%, a specific impregnating compound can be selectively combined, and the raw materials can be prepared into the plant culture medium. Under the conditions that exogenous microorganisms are not introduced and plant tissue structures are not damaged, the catalytic function of an endogenous metabolic enzyme system is safely and efficiently restarted and maximally promoted, and components of a plant body are driven to realize directional biotransformation. According to the process, conversion of primary metabolites and / or secondary metabolites is remarkably promoted, the content conversion of one or more beneficial components in the primary metabolites and / or the secondary metabolites is improved, and meanwhile, the biological and pharmaceutical structures and inherent metabonomics characteristics of the plants are completely reserved. The biotransformation product can be used as a high-quality raw material to be applied to medicines, common foods, health foods, special diet foods, daily chemical products and disinfection products, and can be further prepared into traditional Chinese medicine decoction pieces, solid preparations, semi-solid preparations and liquid preparations by adding or not adding pharmaceutically acceptable auxiliary materials.

The present disclosure relates to a carbon dioxide reduction reaction (CO2RR) catalytic system having a dual catalysis function for the electroreduction of CO2 into multi-carbon products, the catalytic system comprising: a first catalyst layer comprising a support and a first metal-based catalyst that is configured to sustain reduction of CO2 into CO, wherein the first metal-based catalyst is atomically dispersed on the support; and a second catalyst layer comprising a second metal-based catalyst that is configured to sustain C—C coupling mechanisms to yield multi-carbon products from CO; wherein the first catalyst layer is positioned above the second catalyst layer to generate CO between the first catalyst layer and the second catalyst layer.

The invention belongs to the technical field of ion exchange membranes, and relates to a composite membrane with a high ion selective catalytic function and a preparation method thereof. The composite membrane has a three-layer structure, namely a high-ion-selectivity base membrane doped with a microporous material and catalytic functional composite layers doped with a positive electrode catalyst and a negative electrode catalyst on two sides of the base membrane. The preparation method comprises the following steps: firstly, dissolving perfluorinated sulfonic acid resin in an organic solvent, then dividing the obtained solution into three parts, and respectively adding a microporous material, a positive electrode catalyst and a negative electrode catalyst into the three parts for dispersion; after concentration treatment, a step-by-step tape casting mode is adopted to sequentially prepare a high-ion-selectivity base membrane, a positive electrode catalytic function composite layer and a negative electrode catalytic function composite layer, and finally, the three layers are compounded to form the high-ion-selectivity catalytic function composite membrane. The prepared composite membrane endows the flow battery diaphragm with a catalytic function; through fusion of the catalyst and the diaphragm resin, the problem of catalyst shedding is solved, and the conductivity and the ion barrier ability of the diaphragm are improved at the same time.

The invention discloses Cu / CuO / Ag nano-particles and a preparation method and application thereof, and the method successfully prepares the Cu / CuO / Ag nano-particles with regular morphology and uniform dispersion by optimizing a dual-stabilizer system and a step-by-step reduction-replacement process. The material has dual functions of SERS enhancement and catalysis: as an SERS substrate, the enhancement factor of rhodamine 6G reaches 5.3 * 10 < 8 >, the detection limit is as low as 5.0 * 10 <-13 > mol / L, and the reproducibility is good (RSD = 6.2%); meanwhile, as a catalyst for hydrazinolysis and reduction reaction, by optimizing a reaction solvent and the pH value of a system, the reaction efficiency is remarkably improved, and an additional incubation step is not needed. The detection limit on the plasticizer DOTP can reach 2.0 * 10 <-9 > mol / L, and the method has the advantages of simplicity and convenience in operation, good reproducibility, high analysis speed and the like, and is suitable for rapid screening and quantitative analysis of plasticizers in food packaging, environmental water bodies and medical instruments.

The invention discloses a difunctional alcohol dehydrogenase derived from Geobacillus thermodenitrifis, the difunctional alcohol dehydrogenase takes NAD < + > as a cofactor, can specifically catalyze a continuous oxidation reaction of omega-hydroxy fatty acid, and catalyzes the omega-hydroxy fatty acid to synthesize alpha, omega-binary fatty acid through single enzyme catalysis without an aldehyde intermediate. The alcohol dehydrogenase has dual catalytic functions of alcohol oxidation and aldehyde oxidation, the oxidation process from hydroxymethylene to carboxyl can be completed in one step, the reaction steps are simplified, accumulation and separation of intermediate aldehyde are avoided, the conversion efficiency is improved, and the alcohol dehydrogenase is alpha, omega-dibasic fatty acid and is a novel alcohol dehydrogenase. The invention provides a simple and efficient biocatalysis way for biosynthesis of dodecanedioic acid, especially dodecanedioic acid, and has important industrial application value.

The application provides a preparation method of a Pickering type SCR catalytic functional emulsion containing composite metal oxide particles. The composite metal oxide particles prepared by a wet chemical method are used as emulsifiers, water is used as a continuous phase, and a water-insoluble organic solvent is used as a dispersed phase. The stable O / W type catalytic functional emulsion is obtained by high-speed shearing homogenization and emulsification in a sealed container. The composite metal oxide nanoparticles with no irritation, high low-temperature catalytic activity and easily available raw materials are used as the SCR catalyst and emulsifier to replace the traditional surfactant. The Pickering type SCR catalytic functional emulsion prepared by the application has better dispersion performance and stability than the catalytic functional emulsion stabilized by the traditional surfactant. The preparation method is simple, the prepared emulsion can be uniformly loaded on the surface of various filter carriers, the reaction activity of the catalyst is well reserved, and the binding firmness between the catalyst and the filter carrier is high.

The present application relates to the technical field of conductive foil, specifically to a multilayer composite conductive foil and its preparation method and application, specifically comprising the following steps: S1. aluminum foil is immersed in NaOH solution and then cleaned with deionized water, dried to obtain pretreated aluminum foil; S2. using a magnetron sputtering instrument, using a Ti-Zn-C-Ni composite target material to sputter the pretreated aluminum foil, and obtaining a transition layer conductive foil after deposition; S3. the modified functional slurry is coated on the surface of the transition layer conductive foil by a doctor blade coater, then added to an oven for segmented curing, and then annealed, and after cooling to room temperature, a multilayer composite conductive foil is obtained. The present application forms a strong adhesion bottom layer with the substrate through the composite process design of sputtering and coating, blocks the corrosion of electrolyte to the substrate, and also bears the conductive and catalytic functions. The two functional layers obtained by the two processes are further fused through annealing treatment, forming a gradient interface, eliminating interlayer stress, and improving the overall structural stability.

The invention belongs to the technical field of electrodes, and discloses a preparation method of a titanium-based anti-scaling cathode with an electrolyzed water catalysis function, which comprises the following steps: constructing a microstructure on the surface of a titanium mesh substrate; a transition metal catalyst is loaded on the microstructure; the surface of the microstructure material with the catalytic function is coated with an inert coating. The inert coating on the surface of the cathode can prevent electrons from being in contact with water molecules, so that only the tip of the microstructure which is not covered by the inert coating serves as an initial nucleation site of the crystal. When the crystal grows to a micron order, the adhesive force between the crystal and the tip of the microstructure is weakened. Meanwhile, bubbles generated by electrolyzing water can grow along the inert coating and crack near the tip of the microstructure to push the crystals to fall off spontaneously, so that the crystals are prevented from being deposited and accumulated on the surface of an electrode. And meanwhile, metal cations such as Ni < 2 + > and Co < 2 + > loaded on the microstructure can reduce the overpotential of electrolyzed seawater. Due to the two properties, the cathode can be applied to extraction of magnesium resources in seawater.

The invention belongs to the technical field of tea tree gene application, and particularly relates to application of a tea tree CsPHT gene in improving tea geometrid and colletotrichum gloeosporioides resistance of a tea tree. The invention discloses a tea tree CsPHT gene, the nucleotide sequence of the tea tree CsPHT gene is as shown in SEQ ID NO.1, the tea tree CsPHT gene codes 434 amino acid residues, and the amino acid sequence of the tea tree CsPHT gene is as shown in SEQ ID NO.2. The CsPHT gene is proved to be capable of catalyzing biosynthesis of tea tree defense related compounds such as feruloyl putrescine, coumaroyl putrescine and cinnamoyl putrescine for the first time, and the conservation of the catalytic function of the CsPHT gene is proved through heterologous expression. An in-vivo instantaneous function verification result of a tea tree shows that the over-expression of the CsPHT gene can significantly improve the resistance of the tea tree to tea geometrid and tea anthracnose bacteria. The CsPHT gene is proved to be a key positive regulation factor for regulating the resistance of the tea tree to the tea geometrid and the tea anthracnose fungus. The invention provides important gene resources and molecular targets for cultivating new varieties of high-resistance and multi-resistance tea trees.

To provide a honeycomb structure that can realize an economical filter with catalytic function. [Solution] The honeycomb structure has multiple channels through which a fluid passes, and comprises a base material and a catalyst. The base material is provided with a first channel whose fluid outlet end face is sealed and a second channel whose fluid inlet end face is sealed. The catalyst is packed into at least one of the first and second channels.

The application provides a key enzyme involved in glycosylation modification of triterpene saponins, and an application thereof, and belongs to the technical field of genetic engineering. The glycosyltransferase gene is screened based on the omics research of the base plant of traditional Chinese medicine Duanxueliu, i.e. clinopodium gracile, and a pET28a-MBP-CcGT-g51295 prokaryotic expression vector is constructed to successfully obtain the glycosyltransferase. It is found that the glycosyltransferase can catalyze Saikogenin A and Saikogenin F to generate Prosaikogenin A and Prosaikogenin F respectively by using a glycosyl donor UDP-fucose; can catalyze Saikogenin A to generate clinopodiside I and clinopodiside X by using UDP-glucose; can catalyze Prosaikogenin A to generate Saikosaponin B1, Saikosaponin c1 and Saikosaponin X by using UDP-glucose; and can catalyze Prosaikogenin F to generate Saikosaponin A and Buddlejasaponin IV by using UDP-glucose, which reveals the catalytic function of the glycosyltransferase and provides a gene component for the biological research of triterpene saponins, and solves the problem of biological resources of rare saponins.

The invention discloses a ship tail gas denitration and decarburization integrated turbulent flow assembly. The assembly comprises a denitration tower and a decarburization tower which are connected in series. A multi-stage active turbulent flow structure is arranged to strengthen the mass transfer process, a first turbulent flow module made of a catalytic material is additionally arranged in the denitration tower and above a first spraying mechanism and a denitration catalyst, a venturi type cavity is formed in the module, a strong vortex is generated through airflow acceleration and diffusion, and the deep mixing and supplementary catalysis functions are achieved. And a second turbulent flow assembly formed by pore plates is arranged in the decarburization tower and is used for optimizing airflow distribution and creating efficient mass transfer conditions for decarburization liquid which is sprayed downwards. According to the assembly, the gas-liquid mixing efficiency and the reaction rate are systematically improved through a precisely designed turbulent flow structure, so that efficient synergistic removal of NOx and CO2 in ship tail gas is realized in a compact space.

The invention discloses a TEMPO-CNT composite membrane based on layer-by-layer assembly, a preparation method and application, and belongs to the technical field of preparation of electrochemical wastewater treatment materials. According to the composite membrane, a layer-by-layer assembly process is adopted, a carbon-based conductive adsorption layer and a TEMPO catalytic function layer are sequentially constructed on a substrate layer, and an ordered layered structure is formed. According to the structure, the high specific surface area and conductivity of the carbon material are fully reserved, TEMPO active sites are uniformly exposed, and efficient cooperation of pollutant adsorption and electrocatalytic degradation is achieved. The composite membrane prepared by the invention can be adapted to various electrochemical systems such as direct current and alternating current (pulse), trace organic pollutants in wastewater can be efficiently removed with low energy consumption by applying corresponding voltage, and the composite membrane has the advantages of flexible operation, wide application scene, good environmental compatibility and the like.

This invention provides an Ag-doped photocatalytic composite membrane, its preparation method, and its application, relating to the field of water treatment membrane technology. The Ag-doped photocatalytic composite membrane of this invention has a composite functional structure consisting of a polyester nonwoven fabric support layer, a PVDF base membrane core layer, an Ag-BaTiO3 / ZnIn2S4 piezoelectric-photocatalytic functional layer, and a polydopamine hydrophilic protective layer, arranged sequentially. By constructing an Ag-doped dual piezoelectric coupled heterojunction system, introducing the surface plasmon resonance effect of Ag ions, and combining plasma-assisted deposition technology with the composite functional structure, this invention achieves a wide spectral response (UV to near-infrared), highly efficient piezoelectric-photocatalytic synergistic degradation, robust catalyst adhesion to prevent detachment, and multiple effects of "separation-degradation-self-cleaning." This solves the problems of traditional piezoelectric-photocatalytic membranes in terms of catalytic efficiency, long-term stability, and industrial adaptability, and has good application prospects.

Provided is a method for forming a graphene structure without forming a catalytic metal layer and activating the same, the graphene structure forming method including: a step of preparing a substrate to be processed; and a step of forming a graphene structure on a surface of the substrate to be processed by using a carbon-containing gas as a film forming raw material gas in a state in which the surface of the substrate to be processed has no catalytic function, and performing remote microwave plasma CVD.

The invention provides a method for strengthening migration and arrangement of metal type nano particles in an aquifer medium. Comprising the following steps: constructing a mesoporous silica coating layer on the surface of a metal type nano particle, then dispersing the metal type nano particle in water, and performing dispersion treatment to obtain a particle suspension; and injecting the particle turbid liquid into the aquifer medium to be treated, so that the nano particles are migrated and dispersed into pore channels of the aquifer medium. The metal nanoparticles are coated with the mesoporous silica, and the coating layer is used as a physical barrier, so that particle aggregation is effectively inhibited, and long-time stable dispersion of the metal nanoparticles in a system is ensured; meanwhile, contact with porous media is reduced, and the migration performance is remarkably improved. In addition, the mesoporous structure on the coating layer can expose active sites of the inner core metal type nanoparticles, so that the material is endowed with reaction capacity. According to the method, the catalytic function is reserved while long-distance migration of the metal type nanoparticles is achieved, and the mesoporous silica is environmentally friendly and free of secondary pollution risks.

The application discloses a compound for targeting IRAK4 protein degradation and application thereof. The compound is a compound shown in formula I, and formula I is T-L-E. In formula I, T is selected from groups shown in formulae T-1 and T-2; E is selected from groups shown in formulae E-1, E-2 and E-3; and L is a linking group with a length of 0-15 atoms. The compound adopts a double-target molecule structure, wherein one end of the molecule is targeted to combine with E3 ligase, and the other end of the molecule is targeted to combine with a target protein (IRAK4 protein) to be degraded. The two ends of the structure are connected through a chain (linker) to form a complete compound molecule. The molecule can reduce the IRAK4 protein level, so that the kinase catalytic function and the scaffold function of the IRAK4 protein are lost at the same time, and a new direction is provided for the treatment of IRAK4 related diseases.

This invention relates to the field of catalyst preparation technology, specifically disclosing a microwave-absorbing carbon-coated Fe2N catalyst, its preparation method, and its application in Fischer-Tropsch synthesis. The catalyst provided by this invention uses Fe2N particles with microwave-absorbing properties as the core, coated with an outer carbon shell, forming an Fe2N@C core-shell composite structure. The carbon coating layer can, to a certain extent, inhibit the agglomeration and sintering of Fe2N particles, improve the structural stability of the catalyst, and regulate its surface properties and active phase evolution behavior. Furthermore, the Fe2N@C composite material can absorb electromagnetic waves and convert them into heat energy, providing a material basis for heating and energy utilization in microwave-assisted Fischer-Tropsch synthesis. The preparation method of this invention is simple, and the resulting catalyst possesses both electromagnetic wave absorption and Fischer-Tropsch synthesis catalytic functions, providing a new material system for the functional design of iron-based catalysts and their application in microwave-enhanced Fischer-Tropsch synthesis.

The present application relates to the technical field of biosynthesis, and specifically discloses a method for selectively hydroxylating 16-position of dehydroabietyl acid based on CYP153 family cytochrome P450 enzyme, which comprises the following steps: plasmid construction, heterologous expression of CYP153A99-RhFRED in Escherichia coli, heterologous expression of opt13 in Escherichia coli, and crude enzyme catalytic conversion reaction. By optimizing the codon bias of the protein sequence of cytochrome monooxygenase in the CYP153 family, the p450 enzyme CYP153A99 with the biological catalytic function of catalyzing the hydroxylation of C16 position of dehydroabietyl acid is obtained, high-site selective oxidation of dehydroabietyl acid is realized, the substrate spectrum and application field of the CYP153 family P450 enzyme are expanded, and a new technical path is provided for the green synthesis of dehydroabietyl acid derivatives.

The invention belongs to the technical field of separation membrane materials, and relates to a preparation method and application of a one-step bionic beetle catalytic membrane, and the preparation method comprises the following steps: directly dispersing a hydrophilic nano-catalyst in a trifluoroacetic acid membrane casting solution of PET, and carrying out one-step molding through a non-solvent induced phase separation technology. In the phase inversion process, the catalyst spontaneously segregates and is anchored on the surface of the membrane and in pore channels to form a'hydrophilic bulge-hydrophobic substrate 'heterogeneous wetting structure simulating the backs of desert beetles, so that one-step in-situ integration of a membrane matrix, bionic morphology and a catalytic function is realized. The prepared membrane has excellent oil-water separation performance and catalytic degradation capability, the water-in-oil emulsion separation efficiency is greater than 99.5%, and organic pollutants can be rapidly degraded in the presence of hydrogen peroxide. The invention has the advantages of simple and efficient process, low cost and stable structure, and is suitable for advanced treatment and synchronous purification of complex oily wastewater.

The invention discloses a self-luminous-catalytic functionalized MnO2 nano particle as well as a preparation method and application thereof. The self-luminous-catalytic functionalized MnO2 nano particle is obtained by the following steps: firstly, obtaining an H-MnO2 nano particle; then, sequentially modifying the surfaces of the H-MnO2 nano particles with PAH (Polyacrylamide) and PAA (Polyacrylamide) to obtain H-MnO2-PP (Polypropylene); then, Ce6, CPPO and GOx are loaded into the cavity of the H-MnO2-PP; and finally, covalently coupling Ang-2 to the surfaces of the nanoparticles. The invention provides an application of a self-luminous-catalytic functionalized MnO2 nano particle in preparation of a drug for treating brain glioma. The self-luminous-catalytic functionalized MnO2 nano particle integrates multiple functions of hunger treatment, oxygen self-supply and CLE-PDT, not only solves the problem that the curative effect of traditional PDT is limited due to insufficient penetration depth of a light source, but also enhances the treatment effect on brain glioma through multi-mode synergy.

The application provides a catalyst for electro-thermal catalytic methane dry reforming reaction and a preparation method thereof, a nanometer Ni catalyst loaded on an Al2O3-TiO2 composite oxide coating prepared on the surface of carbon fiber is constructed to build an integrated material system with transient thermal response capability and catalytic function synergy, so that mechanism driven optimization of DRM reaction, efficient conversion of electric energy into chemical energy and long-term stable operation in a high-temperature CO2 environment are realized. The catalyst is constructed on the surface of carbon fiber through electro-thermal induction, has the characteristics of high interface stability, fast electro-thermal response and strong catalytic activity and the like, is suitable for methane reforming reaction in a high-temperature dry gas environment, is especially suitable for an electro-thermal catalytic system driven by a pulse current and has the application potential of efficient conversion of green electric energy into chemical energy.

The invention discloses a low-temperature moisture-proof catalyst with ozone decomposition and VOCs concerted catalysis functions and a preparation method and application, and belongs to the technical field of waste gas treatment, the preparation method comprises the following steps: S1, adding starch into a sodium sulfite solution, and mixing to obtain a precipitation solution; dissolving a copper source and a manganese source or a copper source, a manganese source and a cerium source in water to obtain a metal salt solution; s2, under the stirring condition, dropwise adding the precipitation solution into the metal salt solution until the solution is alkaline; continuously stirring and reacting to obtain a precursor; s3, calcining the precursor to obtain the low-temperature moisture-proof catalyst. The catalyst has the advantages of beneficial activity, good stability, simple preparation method and the like.

The invention belongs to the field of biotechnology and enzymology, and particularly relates to a thermostable variant of MDH and application thereof. The amino acid sequence of the mutant is shown as any one of SEQ ID NO: 1 to SEQ ID NO: 23. The catalyst has a normal MDH catalysis function and shows high temperature stability. The thermal stability variant of MDH provided by the invention can be used for replacing traditional MDH to be applied to clinical diagnostic reagents, cold-chain transportation and low-temperature storage are avoided, the cost is reduced, and the shelf life is prolonged.

The invention relates to the technical field of photo-thermal interface evaporation and photo-thermal catalysis, in particular to a preparation method and application of a MnO2-based photo-thermal evaporator with a photo-thermal catalysis function. The preparation method comprises the following steps: S1, preparing a pretreatment carrier: S101, cleaning the carrier to remove impurities; s102, carrying out pretreatment; s2, preparing a composite MnO2 precursor solution; and S3, loading MnO2 by an impregnation method. According to the preparation method and application of the MnO2-based photo-thermal evaporator with the photo-thermal catalysis function, the problems that manganese dioxide is not firmly combined in the photo-thermal evaporator, the adsorption and capture capacity on phenol is weak, catalytic active sites are insufficient, and the degradation efficiency is low are solved.

This invention discloses an alumina-based catalytic ceramic membrane loaded with a high content of iron oxide, its preparation method, and its application, belonging to the technical field of inorganic functional ceramic microfiltration membranes and their preparation. This invention solves the problems of low catalyst loading limiting the catalytic activity of existing catalytic ceramic membranes, as well as the complex and costly preparation processes. In preparing the alumina-based ceramic membrane, this invention adds silica to generate a liquid phase during sintering to promote sintering, and adds the catalyst α-Fe₂O₃ to the ceramic powder before sintering. A one-step co-sintering method is used to prepare a ceramic membrane with catalytic function, simplifying the preparation process while increasing the α-Fe₂O₃ content on the surface and inside of the ceramic membrane, utilizing Fe… 3+ It activates the crystal lattice and promotes sintering. Furthermore, with the increase of α-Fe2O3 addition, small pores are expelled during sintering, pore walls shrink, large pores are generated, the pore size of the ceramic membrane gradually increases, and the permeation flux of the ceramic membrane is improved.

The application provides a multi-layer core-shell structure composite slow-release oxygen particle and a preparation method thereof, which comprises a three-layer structure of a weight-increasing core, an oxygen-releasing intermediate layer and a functional surface layer. The weight-increasing core is a high-density inorganic microsphere selected from one or more of alumina microspheres and silica microspheres, and the composition of the weight-increasing core is a binder and calcium peroxide, and the weight-increasing core has a long-acting slow-release oxygen function, wherein the binder is selected from one of sodium alginate, xanthan gum and guar gum; the composition of the outer shell layer is a binder, a porous adsorption material and a catalytic functional material, wherein the binder is physically crosslinked PVA, the adsorption functional material is selected from one or more of biochar powder, zeolite powder, diatomite and attapulgite, and the catalytic functional material is selected from one or more of iron-carbon powder, nano-iron powder and pyrite powder.

The present invention provides an electrochemical cell electrode that appropriately possesses electronic conductivity, catalytic function, and ionic conductivity. [Solution] The electrochemical cell electrode 10 disclosed herein includes an electron conduction portion 12 mainly composed of an electron conduction catalyst and an ion conduction portion 14. A first layer 10a is formed in the region including the upper surface 10U of the electrochemical cell electrode 10. This first layer 10a includes the electron conduction portion 12 and substantially does not include the ion conduction portion 14. On the other hand, a second layer 10b is formed in the region including the lower surface 10D of the electrochemical cell electrode 10. In the width direction X of this second layer 10b, the electron conduction portion 12 and the ion conduction portion 14 are formed alternately. With this configuration, materials can be arranged according to the differences in required performance in the thickness direction, so that electron conductivity, catalytic function, and ion conductivity can be appropriately exhibited.

This invention discloses a metal-nucleic acid coordination nanosystem, its preparation method, and its application. The preparation process of the nanosystem is as follows: CuCl2 solution, MnCl2 solution, siRNA solution, and EGCG solution are mixed and reacted at 37°C with stirring to obtain preliminary nanoparticles, denoted as Cu-Mn-siRNA; the obtained Cu-Mn-siRNA nanoparticles are mixed with PEI solution and co-incubated for surface coating. After purification, the final target nanomaterial is obtained, denoted as Cu-Mn-siRNA@PEI. After entering tumor cells, the surface-modified PEI enhances the interaction between the nanoparticles and the negatively charged cell membrane through its positive charge, thereby promoting the internalization and uptake of the nanosystem by the cells. Under the high GSH environment within the cells, the coordination structure dissociates, releasing Cu... 2+ Mn 2+ And siGPX4. This nanosystem integrates the catalytic function of bimetallic ions, the gene silencing function of siRNA, the coordination-assisted function of EGCG, and the delivery and stabilization function of PEI, achieving synergistic therapy of "reactive oxygen species generation + target gene silencing".

The invention discloses a hollow fiber ceramic catalytic membrane, a membrane module reaction device and method and application, and belongs to the technical field of water treatment and membrane separation. A membrane separation layer with a catalytic function can be constructed by loading or fixing the nano-catalyst on the pore channels and the surface of the ceramic membrane in situ, and the membrane has the characteristics of excellent chemical stability, high temperature resistance, high pollution resistance, high mechanical strength, long service life and the like, and can tolerate a harsh chemical reaction environment in an advanced oxidation process. According to the hollow fiber catalytic membrane, spinel CoFe2O4 is used as a main active component, so that active oxygen species such as hydroxyl free radicals with strong oxidizing capacity are continuously generated, effective degradation of antibiotics is realized, and the technical problem that pollutants are difficult to effectively remove in an existing method is solved.