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1399results about How to "Avoid inactivation" patented technology

Preparation method of core-shell structured synthetic polymer-natural polymer composite fiber

The invention discloses a preparation method of a core-shell structured synthetic polymer-natural polymer composite fiber, and the method comprises the steps of: (1) selecting one or several of synthetic polymers to dissolve in a solvent, and conducting stirring until complete dissolution; (2) selecting a natural polymer to dissolve in a solvent, or adding a spinning assistant, and carrying out stirring until complete dissolution; and (3) taking the solution prepared in step (1) as an outer tube spinning solution, adopting the solution prepared in step (2) as an inner tube spinning solution, injecting them into the inner tube and the outer tube of a coaxial spinneret, and performing coaxial electrospinning at room temperature. The core-shell structured nano-fiber prepared by the invention selects the synthetic polymer as the shell layer, and can inhibit water molecules from penetrating the natural polymer as the core layer. The natural polymer as the core layer can more effectively encapsulate active substances to avoid inactivation of the active substances in the presence of an organic solvent, so that the core-shell structured composite fiber can play a good drug sustained release role in the drug carrier field, and an integral activity can be maintained.
Owner:SHANGHAI JIAO TONG UNIV +1

Efficient environment-friendly black carp extrusion compound feed and production method thereof

The invention discloses an efficient environmental-friendly black carp extrusion compound feed and a production method thereof. The method is characterized by comprising the following steps: mixing large amounts of other raw materials such as fish meal, extruded-soybean, soybean meal, rapeseed meal, cottonseed meal, wheat and rice bran and then coarsely crushing a mixture; adding spray-dried animal blood cells, larvae powder, monocalcium phosphate, choline chloride and salt for evenly mixing, carrying out superfine crushing; adding vitamin premis, mineral premix, rheum emodin, L-carnitine and allicin for evenly mixing; and carrying out steam tempering, extrusion, granulation, drying, spraying, cooling and the like on the mixed materials to obtain the product. The black carp extrusion compound feed is simple to prepare and has comprehensive and balanced nutrition, the digestibility of the black carp on feed nutrient substances can be improved, the feed coefficient is reduced, and the nitrogen and phosphorus emission is lowered. The feed has good palatability, excellent stability in water, and less feed wastes and water pollution. The feed can increase the immunity, antioxidation and anti-stress capabilities of the black carp, and promotes the growth of the black carp.
Owner:HUZHOU TEACHERS COLLEGE

Kernel-shell structural nanofiber membrane, preparation method thereof and application

The invention discloses a kernel-shell structural nanofiber membrane, a preparation method thereof and an application; the preparation method includes steps of (1), preparation of spinning; dissolving sodium alginate, polyoxyethylene and poloxamer F127 in distilled water, stirring evenly and acquiring shell layer spinning solution; mixing the chitosan nanoparticle solution loaded with active matters with polyving akohol solution evenly, and acquiring the kernel layer spinning solution; (2), coaxial electrostatic spinning: respectively injecting the shell layer spinning fluid and kernel layer spinning fluid in a static spinning device containing a coaxial needle, performing the coaxial electrostatic spinning under room temperature, performing solvent evaporation in the spinning process, and acquiring the kernel-shell structural nanofiber membrane loaded with the nanoparticle. The preparation method is simple in operation and gentle in reaction condition and can well control the slow release of the active matter; moreover, the prepared colon targeting controlled release system has obvious colon targeting property, thereby improving the utilization degree of the active matter. The colon targeting controlled release system can be applied to functional food domain.
Owner:SOUTH CHINA UNIV OF TECH

Anion modified mercury-free catalyst for ethyne hydrochlorination reaction, and preparation method thereof

The invention discloses an anion modified mercury-free catalyst for an ethyne hydrochlorination reaction, and a preparation method thereof. The catalyst comprises a catalyst carrier and an active component, wherein the catalyst carrier is active carbon, the active component is a sulfate, a chloride, a phosphate or a pyrophosphate of copper or tin, and the carrier is acid-washed active carbon or phosphorus doped active carbon. The preparation method comprises preparing an active component impregnating solution, adding a catalyst carrier to carry out equivalent volume impregnation, drying, baking and other process steps. According to the present invention, acetylene and hydrogen chloride are mixed and then are subjected to a reaction in the catalyst system, wherein the catalysis system of the present invention has characteristics of environmental protection and safety compared with the current mercury catalyst in the industry; and the catalyst prepared by the preparation method has characteristics of high activity, high selectivity, good stability, and longer service life, and is more suitable for ethyne hydrochlorination reactions for producing vinyl chloride through a calcium carbide method compared with the general mercury-free catalyst.
Owner:TIANJIN UNIV

Preparation method and application of immunosensor based on dopamine biomemetic modification

ActiveCN103575874ASolving Synthetic DifficultiesSolving the lack of simplicityMaterial analysis by electric/magnetic meansDisease diagnosisNanomaterialsMultiple tumors
The invention discloses a preparation method and application of a non-enzymatic electrochemical immunosensor based on dopamine biomemetic modification and relates to the fields of nano-science, biological immune technology, electrochemical sensing and the like. An electrode is functionalized by utilizing dopamine biomemetic modification, and platinum, silver, palladium and other metal nanoparticles with enzymatic activity are synthesized in situ by utilizing the reduction characteristic of a poly-dopamine modification layer; an antibody is immobilized on the surface of the electrode by means of the interaction of the metal nanoparticles and poly-dopamine modification layer; electrochemical immunoassay on a tumor marker can be realized based on the electrocatalytic effect of the metal nanoparticles to an H2O2 reduction reaction and the identification effect of the antibody molecule to an antigen. The method is simple in steps, easy to operate and low in cost, has a high electrochemical activity and excellent response performance, can solve the problem of difficult nano-material synthesis in a conventional method and lack of simple and effective method, is applicable to preparation of multiple tumor marker immunosensor electrodes, and has a wide application prospect in scientific research and clinical application.
Owner:UNIV OF JINAN

Production process of garden plant waste compost bacterium and uses thereof

The invention relates to a method for making landscape plant waste compost inoculum and an application of the same. The method is as follows: bacillus subtilis, trichoderma viride, lactobacillus plantarum, paracoccus denitrification, aspergillus oryzae and saccharomyces cerevisiae respectively occupying 10 to 20 mass portions are inoculated in a solid state fermentation medium so as to carry out cultivation and fermentation in dark sealing for 1 to 3 weeks at a temperature of between 25 and 30 DEG C; one week later, 250 mass portions of saw dust is added and evenly stirred and then cultivation and fermentation are continued; two weeks later, hay is placed to absorb surplus moisture and then is removed, and powdery inoculum can be obtained through drying in the shade for further use. Garden wastes are piled up and then are inoculated with inoculum with the weight occupying 1 to 3 per mill of that of a pile and dipped in warm water at a temperature of between 30 and 40 DEG C; compost is carried out at a temperature of between 55 and 65 DEG C, and pile turning and water replenishing are carried out every 3 to 4 days; then, pile turning and water replenishing are carried out every two weeks so as to keep pile water content of between 50 and 60 percent; thus, compost is completed after three weeks so as to reach to rotten innocuity standards. The strain has simple making and low cost, and can be directly used or bred continuously; moreover, the strain has no variation, no inactivation and long storage period, and the obtained compost can improve soil and increase nutrient utilization rate.
Owner:龙地(上海)建设发展有限公司
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