171 results about "Allergic anti" patented technology

The invention discloses a preparation method and application of a chaenomeles speciosa extract, and the preparation method comprises the following steps: S1, crushing a chaenomeles speciosa raw material, sieving, and uniformly mixing with water to obtain a first mixture; s2, adding compound lactic acid bacteria liquid into the first mixture, and performing heat-preservation fermentation to obtain a second mixture; s3, performing ultrasonic extraction on the second mixture, and then performing ceramic membrane filtration, vacuum concentration, sterilization and drying to obtain the chaenomeles speciosa extract. The extraction efficiency in the preparation process of the chaenomeles speciosa extract is remarkably improved by optimizing the technological process, the extracted chaenomeles speciosa extract shows excellent anti-oxidation, anti-aging, hypoglycemic, anti-allergic and anti-inflammatory effects, and a novel functional component source is provided for the fields of food and skin care products.

The present invention provides antibodies binding to birch pollen allergens, in particular to Bet v 1 allergens, and also binding to Bet v 1 homologous allergens. The present invention also provides compositions and kits comprising distinct antibodies binding to distinct, non-overlapping epitopes of Bet v 1 and Bet v 1 homologous proteins. In addition, the present invention also relates to the use of such antibodies, compositions and kits, e.g. for preventing or treating tree pollen allergies as well as food-related allergies.

The present invention provides antibodies binding to birch pollen allergens, in particular to Bet v 1 allergens, and also binding to Bet v 1 homologous allergens. The present invention also provides compositions and kits comprising distinct antibodies binding to distinct, non-overlapping epitopes of Bet v 1 and Bet v 1 homologous proteins. In addition, the present invention also relates to the use of such antibodies, compositions and kits, e.g. for preventing or treating tree pollen allergies as well as food-related allergies.

The invention provides a biological combined preparation for allergic rhinitis and a preparation method of the biological combined preparation. The preparation comprises antibacterial polysaccharide, a centipeda minima extract, anti-allergic probiotics, an active polypeptide compound, sodium hyaluronate, an immunomodulator, a penetration enhancer, a biological adhesive and the like. Wherein the antibacterial polysaccharide can be selected from various natural polysaccharides; the centipeda minima extract is obtained by a specific ethanol reflux method; the antiallergic probiotics comprise lactobacillus acidophilus, lactobacillus rhamnosus and lactobacillus reuteri; the active polypeptide compound consists of thymosin, glutathione and osteogenic peptide. The preparation method comprises the following steps: sequentially mixing the components, carrying out high-pressure homogenization treatment, carrying out ultrasonic treatment, adding probiotics, stirring, intercepting with an ultrafiltration membrane, freeze-drying and the like. The preparation disclosed by the invention can form a uniform nano-scale particle suspension, so that the release rate and the absorption efficiency of the medicine are further improved, and an efficient, safe and convenient novel method is provided for treating the allergic rhinitis.

The present invention relates to the field of pharmaceutical chemistry, and discloses a salt of carebastine and its use, which solves the problems of the prior art, such as poor solid form of carebastine, many impurities, instability, difficulty in purification, difficulty in mass synthesis, and inapplicability to medicinal use. The salt of carebastine of the present invention includes, but is not limited to, acid salts or base salts, particularly potassium salt, sodium salt, methanesulfonate salt and p-toluenesulfonate salt. The salt of carebastine of the present invention is used in the preparation of drugs for histamine H1 receptor antagonists. The salt of carebastine of the present invention has the characteristics of easy purification, high stability, simple process, easy industrial production, and good hygroscopicity and convenient storage. And the salt of the present invention can enter the body quickly and exert its medicinal effect, has good oral absorption, and is superior to ebastine in both safety and individual variation, and is a promising anti-allergic disease drug for development.

The invention provides a breathable anti-allergic fabric and a preparation process thereof, and belongs to the technical field of fabric preparation. The preparation process comprises the following steps: preparing the thermo-sensitive nanoparticles; carrying out graft modification on the polyester fiber by the thermo-sensitive nano particles; co-grafting the polylysine and the elastin to modify the mixed fiber; and preparing the breathable anti-allergic fabric. The fabric creatively adopts a three-layer composite structure, a base layer is formed by blending grafting modified cotton fibers, natural bamboo fibers and modal fibers, a breathable skin-friendly foundation is formed, a middle functional layer is formed by thermo-sensitive nanoparticle grafting modified polyester fibers, nano-silver is antibacterial, sodium bismuthate is used for decomposing allergens through photocatalysis, meanwhile, the breathability of the polyester fibers cannot be reduced, and the fabric is comfortable to wear and comfortable to wear. The plant protein fibers and the polylactic acid fibers on the surface layer are interwoven to form a fine net, allergens are prevented from invading, steam is guaranteed to flow smoothly by means of fiber characteristics, and therefore excellent air permeability is guaranteed.

The invention provides kelp fucoidin with low molecular weight and high anti-anaphylaxis as well as a preparation method and application thereof, and belongs to the technical field of food processing. The preparation method comprises the following steps: mixing kelp fucoidin with water to obtain a kelp fucoidin solution; and mixing the kelp fucoidin solution with H2O2 and Vc, reacting, adjusting the pH value, dialyzing and freeze-drying to obtain the kelp fucoidin with low molecular weight and high anti-allergic property. The H2O2-Vc degradation system is innovatively applied to preparation of the low-molecular-weight kelp fucoidin and improvement of the anti-allergic activity of the low-molecular-weight kelp fucoidin. In the degradation process, the chemical composition of the fucoidin is partially changed, but monosaccharide types and functional groups are not influenced. Through multiple ways of cell model and animal model experiments, the degraded laminaria fucoidin is more prominent in anti-allergic activity. Technical support is provided for development of seaweed-derived anti-allergic functional active substances, and high-valued utilization of kelp resources in the fields of functional food and medicines is further promoted.

The invention relates to the technical field of masks, and particularly discloses a whitening and spot-fading mask and a preparation method thereof.The whitening and spot-fading mask is prepared from, by mass, 5-10 parts of green tea extract, 5-10 parts of licorice extract, 10-20 parts of arbutin, 30-45 parts of vitamin C, 3-9 parts of hyaluronic acid, 20-30 parts of nicotinamide, 15-30 parts of sea buckthorn fruit oil and 3-9 parts of nonapeptide-1; the mask is mainly composed of a green tea extract, a licorice extract, arbutin, vitamin C, hyaluronic acid, nicotinamide, fructus hippophae oil and nonapeptide-1, the use of preservative components is greatly reduced, and the cooperation of the licorice extract and arbutin improves the anti-inflammatory and anti-allergic properties of the mask and blocks the generation of melanin. Through the cooperation of the sea buckthorn fruit oil, the vitamin C and the nonapeptide-1, the moisture retention and the elasticity of the skin can be effectively improved, the effects of whitening the face and fading spots are achieved, and meanwhile, the use comfort of the mask is also effectively improved.

The invention belongs to the technical field of cosmetics, and discloses an anti-allergic composition containing a leukocyte extract as well as a preparation method and application of the anti-allergic composition. The antiallergic composition comprises the following components: a leukocyte extract, polysaccharide, a tremella sporocarp extract and taurine, wherein the polysaccharide comprises fructo-oligosaccharide and inulin. According to the anti-allergic composition, on the basis of containing the leukocyte extract, the polysaccharide, the tremella sporocarp extract and the taurine are compounded, so that the synergistic effect can be achieved, the anti-allergic effect of the leukocyte extract is effectively improved, and the usage amount of the leukocyte extract in the field of skin care products can be reduced.

The invention relates to the technical field of collagen dressings, in particular to a moisturizing and repairing collagen dressing and a preparation method thereof. The moisturizing and repairing collagen dressing is prepared from the following components in parts by mass: 10 to 30 parts of recombinant human fibronectin, 10 to 20 parts of recombinant collagen, 5 to 15 parts of beta-glucan, 5 to 10 parts of compound hexanediol, 40 to 50 parts of carbomer, 5 to 15 parts of a flavoring agent, 80 to 120 parts of purified water, 10 to 30 parts of a modified recombinant human III type collagen solution and 10 to 20 parts of a modified chitosan solution. The recombinant human fibronectin disclosed by the invention can be deposited at an injured part to form a blood clot, so that the aim of stopping bleeding is fulfilled, and the subcutaneous tissue is protected; the recombinant collagen has high biological activity and can inhibit inflammation and improve the conditions of pachulosis, damage and the like of the skin; the beta-glucan can generate cytokines, promote healing of skin with laser-dependent dermatitis or barrier damage, and realize anti-allergic and anti-inflammatory effects.

The invention discloses low-irritation cyhalothrin and a preparation method and application thereof, and belongs to the technical field of pesticide preparations, the low-irritation cyhalothrin comprises silicon dioxide nanoparticles with the surfaces grafted with amphiphilic copolymers, cyhalothrin and an anti-allergic drug, the silicon dioxide nanoparticles with the surfaces grafted with the amphiphilic copolymers are dispersed in a solvent, and the anti-allergic drug is added to the silicon dioxide nanoparticles with the surfaces grafted with the amphiphilic copolymers to prepare the low-irritation cyhalothrin. The preparation method comprises the following steps: taking porous silicon dioxide nanoparticles as a carrier, modifying a layer of amphiphilic polymer on the surface of silicon dioxide in situ, then adding cyhalothrin and an anti-allergic drug, continuously stirring, and drying the obtained product to obtain the low-irritation cyhalothrin. The cyhalothrin and the anti-allergic drug are loaded in silicon dioxide pore channels, and the anti-allergic agent is used in cooperation, so that the skin irritation of the cyhalothrin is reduced. The cyhalothrin with low irritation provided by the invention is simple in preparation method, can be used as a cyhalothrin insecticide raw medicine, and has relatively great market application potential.

The invention discloses a traditional Chinese medicine compound xanthium sibiricum composition as well as a preparation method and application thereof. The traditional Chinese medicine compound xanthium sibiricum composition comprises xanthium sibiricum, radix angelicae, magnolia flower and mint. The preparation method comprises the following steps: S1, taking 6-10 parts by mass of fructus xanthii, 6-10 parts by mass of radix angelicae, 6-10 parts by mass of flos magnoliae and 6-10 parts by mass of mint, drying, and mixing to obtain a mixed raw material; and S2, adding 7-16 times of distilled water into the mixed raw material, soaking in cold water, decocting with big fire until boiling, decocting with small fire for half an hour, filtering, collecting liquid medicine, adding 5-14 times of distilled water into medicine residues, and decocting with the same method. Combining the two liquid medicines, concentrating under reduced pressure, and drying in an air dry oven to obtain a water-extracted dry extract of the four medicinal materials; according to the preparation method of the traditional Chinese medicine composition granules, research is carried out around the preparation process and the quality standard, a medicine which is reasonable in process, reliable in quality, stable and effective is provided for clinical treatment of allergic rhinitis, effective components in the medicinal materials are fully extracted, and the curative effect of the traditional Chinese medicine composition granules for resisting allergic rhinitis is definite.

The invention discloses an anti-allergic probiotic composition as well as a preparation method and application thereof. The probiotic composition is prepared from the following raw materials in parts by weight: 10 to 50 parts of lactobacillus reuteri PG-LRL116, 10 to 50 parts of lactobacillus acidophilus, 10 to 50 parts of lactobacillus rhamnosus, 10 to 30 parts of lactobacillus gasseri, 10 to 30 parts of lactobacillus salivarius, 5 to 15 parts of cordyceps militaris aqueous extract, 5 to 15 parts of rosemary aqueous extract and 5 to 15 parts of dendrobium huoshanense yeast. The preparation method of the probiotic composition comprises the following steps: preparing the cordyceps militaris aqueous extract, the rosemary aqueous extract and the dendrobium huoshanense yeast; the preparation method comprises the following steps: uniformly mixing lactobacillus reuteri PG-LRL116, lactobacillus acidophilus, lactobacillus rhamnosus, lactobacillus gasseri, lactobacillus salivarius, a cordyceps militaris aqueous extract, a rosemary aqueous extract and a dendrobium huoshanense fermentation product, so as to prepare the anti-allergic probiotic composition. The probiotic composition disclosed by the invention can be used for effectively inhibiting the occurrence of food sensitization reaction.

The invention relates to the technical field of skin care products, in particular to whitening essence and a preparation method thereof, and the whitening essence comprises the following components: phenylethyl resorcinol, tetrahydrocurcumin, plant polyphenol and a liquid preparation. According to the whitening essence and the preparation method thereof, generation of skin melanin can be effectively inhibited, and the whitening essence has good anti-inflammatory and anti-allergic effects, can prevent pigmentation caused by inflammation, and also has anti-saccharification and skin color uniformizing effects.

The invention relates to an anti-allergic soothing cosmetic and a preparation method thereof. The invention discloses an N-Ala-Phe-Cys-C aqueous solution or an external cosmetic containing N-Ala-Phe-Cys-C for the first time, wherein the N-Ala-Phe-Cys-C aqueous solution or the external cosmetic has anti-allergic soothing effects. The eye cream has excellent single-time and multi-time skin external application safety, and is free of irritation to eyes. Compared with a blank control group, the cosmetics prepared from the 0.01-10% N-Ala-Phe-Cys-C aqueous solution and the formulas 1-4 of the embodiments 5-7 have a remarkable itching relieving effect, and have an inhibiting effect on allergic itching caused by histamine phosphate. Compared with a blank control group, the 0.05%-10% N-Ala-Phe-Cys-C aqueous solution and various formula cosmetics in embodiments 5-7 have a remarkable inhibition effect on auricle swelling caused by xylene.

This invention relates to the field of microbial technology, specifically to a *Lactobacillus plantarum* YYS-B1 strain with hyaluronidase inhibitory activity and its applications. *Lactobacillus plantarum* (… Lactiplantibacillus plants YYS-B1 was deposited at the China General Microbiological Culture Collection Center (CGMCC) on June 12, 2023, with accession number CGMCC No. 27599. This *Lactobacillus plantarum* YYS-B1 exhibits excellent acid and bile salt resistance, enabling it to successfully reach the intestines and exert its probiotic effects. It also demonstrates outstanding anti-allergic, anti-inflammatory, and antioxidant capabilities, specifically exhibiting high hyaluronidase inhibition, strong free radical scavenging ability, and a good inhibitory effect on inflammatory responses caused by allergies. Therefore, it has significant application value and can be used in the development of functional products.

The present invention relates to the technical field of daily chemicals, and in particular to an anti-allergic repair composition, application, and preparation method. The repair composition comprises: gentian root extract, chamomile flower extract, licorice inflata extract, butylene glycol, and water. The anti-allergic repair provided by the present invention is compounded with plant extracts to achieve better anti-allergic repair effects, enhance skin immunity, and reduce skin sensitivity.

The present invention relates to the technical field of plant compositions, and in particular to a plant anti-allergic, antipruritic and analgesic composition and its application. The present application discloses a plant anti-allergic, antipruritic and analgesic composition, which comprises the following raw materials by weight percentage: gentiana cyanus extract: 0.5%-5%, kava root extract: 1%-10%, prickly pear cactus leaf extract: 0.5%-5%, Centella asiatica extract: 1%-10%, and the balance is water. The present application provides a plant anti-allergic, antipruritic and analgesic composition, which achieves the effects of anti-inflammatory, anti-allergic, antipruritic and analgesic by inhibiting NO generation, inhibiting histamine pathways and inhibiting TRPV1 ion channels.

The invention discloses a manufacturing process of an anti-inflammatory and anti-allergic gambiered canton gauze headscarf, and belongs to the technical field of textile technologys.The manufacturing process comprises the steps that 1, mulberry silk with soft luster and fine texture is selected, and mulberry silk fabric is preliminarily cleaned and finished to remove impurities; 2, rhizoma dioscoreae cirrhosae is ground, juice is extracted, the mulberry silk fabric is soaked in the rhizoma dioscoreae cirrhosae juice so that the fabric can fully absorb pigment, the fabric is taken out and aired, the color of the rhizoma dioscoreae cirrhosae juice can be fixed under the sun, the dip dyeing and airing processes are repeated for multiple times, and the color of the fabric is gradually deepened after each time of airing; the gambiered canton gauze headband prepared by the method can prevent the situations of stink, allergy, measles and the like when worn on the head for a long time at high temperature.

Provided is a composition for use in the treatment of inflammatory disease by external use on skin, which comprises dihomo-γ-linolenic acid ethyl ester (DGLA-EE) as an active ingredient. The composition is safe to use and has anti-inflammatory and anti-allergic actions.

Relates to a novel microorganism, a lysate thereof, a culture solution, a culture solution extract and an anti-allergic application thereof. The novel strain according to one aspect and a lysate, a culture solution, a culture solution extract, or a mixture thereof derived therefrom have an effective effect for preventing, ameliorating, or treating allergic diseases.

The invention provides an anti-skid and anti-allergic elastic band and a weaving method thereof. Warp yarns of the elastic band comprise silica gel yarns, polyester filament yarns and latex yarns; the weft yarns are polyester filament yarns. According to the weaving method, from material selection to warping and reverse pan head, knitting on a threading machine and ironing and shaping of post-treatment, the spinning precision is controlled to be within 1cm in bending degree of 100cm and within 0.5 cm in opening degree of 10cm. According to the invention, by selecting proper warp and weft yarns and particularly weaving silica gel yarns on the upper layer of the warp yarns, the anti-skid effect is improved; and the latex threads are woven into the middle layer of the warp yarns, so that the elastic band prepared after ironing and shaping has the functions of deodorization and allergy resistance.

The application provides an extraction method and application of artemisia fiber, and the artemisia fiber is efficiently prepared by the following steps: mild degradation of lignocellulose structure through microbial pretreatment, and dissolution and regeneration in combination with a green solvent system of N-methyl morpholine-N-oxide solution (hereinafter referred to as "NMMO solution"), so that high-value utilization of artemisia waste stems and stalks is realized. The obtained artemisia fiber can retain part of active ingredients from plants, has certain odor removal, antioxidant and anti-allergic potential in food-grade packaging materials and green wallpaper applications, and overcomes defects such as difficult degradation, easy damp and mildew, and single function of traditional packaging materials and wallpapers.

The present application relates to a kind of compositions with anti-inflammatory and anti-allergic effects and its application, and the preparation raw materials of the composition include boletus, phyllanthus and rose apple.The present application uses steam explosion coupling heating reflux preparation to prepare the composition with boletus, phyllanthus, rose apple as preparation raw material, the method not only significantly improves extraction efficiency and biological activity, compared with traditional extraction technology, also avoids the use of organic reagent, more environmentally friendly and safe.

The invention relates to a skin antiallergic composition and a preparation method and application thereof, and the composition is prepared from the following raw materials: sodium cellulose, essence, propylene glycol, a coating solution, a nonionic surfactant and water, the coating solution is prepared by taking modified chitosan microspheres, ascophyllum nodosum extract, chamomile flower extract, centella asiatica extract, anthemis nobilis flower extract, glycerol and water as raw materials, and the modified chitosan microspheres are products obtained by grafting polylactic acid with chitosan. The modified chitosan microsphere can form a nano-micelle with a core-shell structure in a solvent, the ascophyllum nodosum extract, the chamomilla recutita extract, the centella asiatica extract and the anthemis nobilis extract are wrapped in the nano-micelle, the situation that the extracts are degraded or inactivated due to the external environment is avoided, a stable dispersion system can be formed in water, and the stability of the nano-micelle is improved. The plant extract is released after the body surface is coated, and the plant extract and other components synergistically improve the anti-allergic effect of the skin.

The invention relates to the technical field of medical materials, and discloses a preparation method of a multifunctional fiber patch for bone nail fixation postoperative care. The fiber patch adopts a three-layer composite structure design, and comprises an anti-allergic silica gel substrate layer, a drug-loaded nanofiber functional layer and a waterproof breathable layer. The preparation method comprises the following steps: (1) preparing the anti-allergic silica gel substrate layer from platinum cured silica gel and a pressure-sensitive adhesive; (2) preparing a medicine-carrying nanofiber functional layer containing phellinus igniarius polysaccharide through electrostatic spinning; (3) mixing waterborne polyurethane with polytetrafluoroethylene to prepare a waterproof breathable layer; and (4) sequentially compounding the substrate layer, the functional layer and the waterproof breathable layer into the multifunctional fiber patch. The fiber patch has the comprehensive effects of resisting bacteria, resisting inflammation, resisting allergy and easing pain, meanwhile has excellent air permeability and comfort, can effectively promote postoperative wound recovery and reduce infection risks, is particularly suitable for wound nursing after orthopedic internal fixation, and has remarkable clinical application value.

The invention provides herba portulacae herbal cream for eliminating eye wrinkles and a preparation method of the herba portulacae herbal cream, and belongs to the technical field of cosmetics. According to the plant herbal cream, a herba portulacae extracting solution, a birch juice fermentation solution, glycerol, 1, 3-butanediol, 1, 2-pentanediol, betaine, retinol and caffeine are used as a water phase; behenyl alcohol, hexadecanol, tween-20, glyceryl monostearate and triethanolamine are used as emulsifiers; the jojoba oil, the xanthoceras sorbifolia bunge oil and the simethicone are used as oil phases, the moutan bark extracting solution is used as a preservative, the tocopheryl acetate is used as an antioxidant, and the Yulong tea essential oil is used as a flavoring agent. The herbal cream is safe, reliable and anti-allergic, and can effectively eliminate eye wrinkles.

The invention relates to the technical field of collagen dressings, in particular to a moisturizing and repairing collagen dressing and a preparation method thereof. The moisturizing and repairing collagen dressing is prepared from the following components in parts by mass: 10 to 30 parts of recombinant human fibronectin, 10 to 20 parts of recombinant collagen, 5 to 15 parts of beta-glucan, 5 to 10 parts of compound hexanediol, 40 to 50 parts of carbomer, 5 to 15 parts of a flavoring agent, 80 to 120 parts of purified water, 10 to 30 parts of a modified recombinant human III type collagen solution and 10 to 20 parts of a modified chitosan solution. The recombinant human fibronectin disclosed by the invention can be deposited at an injured part to form a blood clot, so that the aim of stopping bleeding is fulfilled, and the subcutaneous tissue is protected; the recombinant collagen has high biological activity and can inhibit inflammation and improve the conditions of pachulosis, damage and the like of the skin; the beta-glucan can generate cytokines, promote healing of skin with laser-dependent dermatitis or barrier damage, and realize anti-allergic and anti-inflammatory effects.

The invention relates to the technical field of cosmetics, and discloses an essential oil composition as well as a preparation method and application thereof. The essential oil composition is prepared from chamomile essential oil, magnolia flower essential oil, lavender essential oil and magnolia flower fermentation product freeze-dried powder. Wherein the magnolia flower fermentation product freeze-dried powder is freeze-dried powder of a product obtained by fermenting a magnolia flower water extract with lactic acid bacteria and saccharomyces cerevisiae; the lactic acid bacteria are lactobacillus plantarum with the serial number of CICC (China General Microbiological Culture Collection Center) 20242; the serial number of the saccharomyces cerevisiae is BNCC 186060. The magnolia flower fermentation freeze-dried powder provided by the invention has very excellent anti-allergic ability, the chamomile essential oil, the magnolia flower essential oil and the lavender essential oil are combined to form the essential oil composition, the allergic reaction can be further relieved, the whole essential oil composition is all natural plant extracts, and the magnolia flower fermentation freeze-dried powder has low irritation and multiple functions and is suitable for large-scale production. The compound is suitable for serving as an active substance of anti-allergic products in the field of cosmetics.

The present invention relates to a composition comprising a mixture of an oat extract and a barley extract, and a use thereof for improving the skin condition of companion animals. The mixture has skin moisturizing, skin barrier strengthening, anti-inflammatory, anti-allergic, and skin soothing effects on companion animals, and thus can be effectively used in cosmetics, medicines and the like.