26 results about "PHENYLETHYL RESORCINOL" patented technology

The invention relates to the field of skincare products, and particularly discloses skincare gel loaded with ganoderma lucidum exosome and a preparation method of the skincare gel. The skin care gel loaded with the lucid ganoderma exosome is prepared from the following raw materials in parts by weight: 20 to 40 parts of hydrogel matrix, 2 to 4 parts of lucid ganoderma exosome nanoparticles, 2 to 6 parts of niobium carbide nanosheets, 1 to 3 parts of nicotinamide, 0.1 to 2 parts of phenethyl resorcinol and 0.1 to 3 parts of green tea extract, the Mailing exosome nanoparticles are of a core-shell structure, a core layer comprises Mailing exosome and papain in a mass ratio of 1: (0.1-0.2), and a shell layer comprises a polylactic acid-glycolic acid copolymer and a penetration enhancer in a mass ratio of 1: (0.1-0.3). The skin-care gel provided by the invention has remarkable whitening, moisturizing and skin brightening effects.

The invention relates to the technical field of skin care products, in particular to whitening essence and a preparation method thereof, and the whitening essence comprises the following components: phenylethyl resorcinol, tetrahydrocurcumin, plant polyphenol and a liquid preparation. According to the whitening essence and the preparation method thereof, generation of skin melanin can be effectively inhibited, and the whitening essence has good anti-inflammatory and anti-allergic effects, can prevent pigmentation caused by inflammation, and also has anti-saccharification and skin color uniformizing effects.

The invention discloses a whitening and spot-fading composition and application thereof, and belongs to the technical field of cosmetics. The whitening and spot-fading composition is prepared from the following components in percentage by mass: 0.1 to 5.0 percent of nicotinamide, 0.0001 to 3.0 percent of tranexamic acid, 0.0001 to 1.0 percent of glycyrrhiza glabra root extract, 0.0001 to 0.4 percent of phenethyl resorcinol, 0.0001 to 2.0 percent of ascorbyl tetraisopalmitate, 0 to 1.0 percent (not including 0) of radix gentianae extract, 0.15 to 4.0 percent of emulsifier, 0.1 to 2.5 percent of antioxidant and the balance of water. By matching with various whitening active ingredients, the comprehensive whitening, brightening and skin improving effects are realized in the aspects of inhibiting melanin generation, blocking melanin transfer, accelerating melanin metabolism and the like; the combination of the specific emulsifier and the thickener can effectively improve the component stability of the composition. The composition is mild in performance, free of irritation to skin and good in market value.

The invention discloses a composition and application thereof, and relates to the technical field of biological medicines and cosmetics. The invention specifically discloses an application of a composition comprising phenylethyl resorcinol and benzylidene dimethoxy dimethyl indanone in the aspects of oxidation resistance, light aging resistance and wrinkle resistance. The expression level of the HO-1 gene can be synergistically improved, and an excellent endogenous anti-oxidation effect is achieved; moreover, the polypeptide also has excellent tightening and anti-wrinkle effects, can synergistically improve the expression level of the COL-1 gene, inhibit the expression level of the MMP-1 gene and improve the expression level of the ELN gene especially in the aspect of UVA light aging resistance, and has the potential of being applied to cosmetics, kits and the like.

The present application relates to a kind of preparation methods of ultra-low profile thick electrolytic copper foil, comprising: i. adding composite additive in foil electrolyte, the composite additive is composed of phenylethyl resorcinol, sodium thiosulfate and diallyl disulfide;II. Adding bismuth sulfate as inorganic additive in roughening solution of surface treatment process.The ultra-low profile thick electrolytic copper foil prepared by the present application has lower surface roughness, and the actual effective copper thickness is close to the theoretical value. Under the same 2-3Oz thickness specification, the effective thickness of the copper foil is thicker than the conventional RTF copper foil. In the PCB circuit, it shows low resistance, less power consumption and better heat dissipation performance, solving the technical problems of high power loss and poor heat dissipation performance under AI high computing power.

The invention relates to an EGCG (epigallocatechin gallate) whitening composition with a barrier repairing effect as well as a preparation method and application of the EGCG whitening composition, and belongs to the technical field of cosmetics. The invention provides an EGCG (epigallocatechin gallate) whitening composition. The EGCG whitening composition is prepared from the following components in parts by mass: 0.1 to 0.5 part of phenylethyl resorcinol, 0.2 to 2.0 parts of orchid fruit leaf extract and 0.1 to 0.5 part of epigallocatechin gallate. The EGCG whitening composition is prepared by matching the phenethyl resorcinol, the orchid fruit leaf extract and the EGCG, and the orchid fruit leaf extract and the EGCG can relieve the irritation of the phenethyl resorcinol, so that the synergistic improvement of whitening and barrier repairing is realized.

The invention discloses a preparation method of phenylethyl resorcinol / sodium alginate emulsion gel beads as well as a product and application of the phenylethyl resorcinol / sodium alginate emulsion gel beads. The method comprises the following steps: firstly, dissolving phenethyl resorcinol in an oil phase, mixing with a water phase containing sodium alginate and a thickening agent, and homogenizing to form an oil-in-water emulsion; then, through an extrusion titration process, the emulsion is dropped into a calcium salt solution to be subjected to an ionic cross-linking reaction, and emulsion gel beads are formed through curing. According to the invention, the problems of poor water solubility, strong irritation and the like of phenylethyl resorcinol are effectively solved by utilizing an emulsion filled gel network structure, and meanwhile, the defect of unstable thermodynamics of the traditional emulsion is overcome. The prepared gel beads are high in sphericity degree, good in mechanical stability and good in mechanical property, can play a dual whitening effect by inhibiting tyrosinase activity and down-regulating protein expression of tyrosinase, and has a wide application prospect in the field of functional cosmetics.

The present application relates to a kind of organosilicon alcohol compositions and its preparation method and application, belong to medical instrument field, medical or dressing preparation field, the specific therapeutic activity of pharmaceutical preparation, the specific use or preparation manufacturing technology field of cosmetic or similar dressing preparation technical field.The organosilicon alcohol composition includes organosilicon alcohol, active ingredient and solvent;The active ingredient includes at least one of ergothioneine, retinol, glutathione, 4-butyl resorcinol, hexyl resorcinol, phenylethyl resorcinol and glabridin.The organosilicon alcohol composition provided by the present application forms complex by using organosilicon alcohol and active ingredient, constructs stable supramolecular system, greatly improves the stability of the obtained composition, and improves skin permeability, and has excellent whitening effect.

The invention relates to the technical field of cosmetics and external preparations, in particular to a phenethyl resorcinol-containing composition as well as a preparation method and application thereof. The composition containing phenylethyl resorcinol is prepared from the following raw materials in parts by mass: 0.5 to 3 parts of recombinant collagen, 0.1 to 1 part of sodium hyaluronate, 0.1 to 1 part of phenylethyl resorcinol, 0.01 to 0.1 part of glabridin, 0.2 to 1 part of beta-glucan wrapped by lipidosome, 1 to 3 parts of composite antioxidant, 0.1 to 1 part of chitosan, 0.5 to 2 parts of emulsifier, 3 to 8 parts of humectant and the balance of water, totaling 100 parts by mass. The composite antioxidant contains 40 wt% or more of shea butter modified by polyhydric alcohol, and the number-average molecular weight of the polyhydric alcohol is 50-200. Through the synergistic effect of beta-glucan and PEG modified shea butter, the transdermal absorption effect of the composition is remarkably enhanced, the blackening phenomenon of the skin is effectively improved, and the moisture content of the skin is increased.

The present application belongs to the technical field of cosmetics, and discloses a composition containing phenylethyl resorcinol and having a whitening effect, and a preparation method and application thereof.The composition comprises components: glabridin, phenylethyl resorcinol and white wine resveratrol.The composition of the present application shows a certain synergy in the four whitening effect paths of resisting oxidative stress, inhibiting melanin production, inhibiting tyrosinase activity and inhibiting MITF-related gene protein expression, has excellent whitening effect, and can achieve excellent whitening effect at a low concentration, can obviously reduce the addition amount of each component in the product, and can also avoid the problem of irritation caused by the excessively high addition amount of a single component.

The application relates to the cosmetic technical field, and particularly discloses a multi-channel whitening and freckle-removing compound and a preparation method thereof. In the multi-channel whitening and freckle-removing compound, the preparation raw materials comprise emollients, moisturizers, skin protectants A, antioxidants, skin protectants B, skin protectants C, a whitening composition, a composite extract and a solvent; the whitening composition comprises niacinamide; the skin protectants C comprise a phenylethyl resorcinol inclusion compound; and the composite extract comprises grape fruit cell extract and cornus officinalis extract. The multi-channel whitening and freckle-removing compound is prepared by compounding multiple functional components, synergistically acts from multiple mechanisms such as inhibiting melanin synthesis, blocking melanin transport, antioxidation and repairing skin barrier, and can realize the high-efficiency whitening and freckle-removing effect while guaranteeing the skin safety.

The present application relates to a kind of EGCG whitening composition with the efficacy of repair barrier and its preparation method and application, belong to the field of cosmetics.The present application provides a kind of EGCG whitening composition, including the following mass parts of components: phenylethyl resorcinol 0.1-0.5 parts, lansan fruit leaf extract 0.2-2.0 parts and epigallocatechin gallate 0.1-0.5 parts.The present application will phenylethyl resorcinol, lansan fruit leaf extract and EGCG be collocated as EGCG whitening composition, lansan fruit leaf extract and EGCG can alleviate the irritability of phenylethyl resorcinol, realize the synergistic improvement of whitening and repair barrier.

The invention relates to the technical field of skin care products, and discloses a whitening active component loaded mesoporous silica nanoparticle whitening essence, which comprises 5-10 parts of a functional mesoporous silica carrier, 2-8 parts of a cosolvent, 10-25 parts of a humectant, 0.1-1 part of a stabilizer, 0.1-0.5 part of a pH regulator, and 70-82 parts of water. The oil-soluble phenylethyl resorcinol / butyl resorcinol and the water-soluble alpha-arbutin are efficiently loaded through the high specific surface area and the controllable aperture structure of the functional mesoporous silica carrier, so that stable coexistence and synergistic effect of double whitening components are realized; vitamin E, ascorbyl palmitate, glutathione, amphiphilic calcium peptide and other components form a synergistic protection system, skin photoaging is delayed, skin endogenous collagen and elastic fiber regeneration is promoted, in addition, sodium hyaluronate, sodium polyglutamate and other moisturizing components can strongly lock water, and moisturizing is achieved.

The present application relates to the cosmetic technical field, especially to a kind of water-based composition containing phenethyl resorcinol and preparation method and application, the preparation raw material of the water-based composition includes: phenethyl resorcinol nano-encapsulated body, oil, water, the mass ratio of the water and oil is (4-15):1.The present application creatively uses water-oil double-layer system to solve the discoloration problem of phenethyl resorcinol, reduces the discoloration risk of phenethyl resorcinol while skin feeling is promoted and appearance is innovated, effectively solves the problem of instability of phenethyl resorcinol in aqueous system, and reduces the irritability of phenethyl resorcinol to skin.

The invention provides a low-cost preparation process for synthesizing phenylethyl resorcinol, which comprises the following steps: taking styrene and resorcinol as raw materials, taking strong-acid styrene cation exchange resin as a catalyst, and reacting at the temperature of 60-80 DEG C to obtain the phenylethyl resorcinol. The method comprises the following steps: carrying out a Friedel-Crafts alkylation reaction in a single solvent to obtain phenylethyl resorcinol, separating a reaction solution from a catalyst, introducing the obtained reaction mother liquor into continuous extraction equipment, adding water, carrying out continuous extraction, concentrating the extracted mother liquor, and purifying to obtain the phenylethyl resorcinol. The recrystallization step comprises the following steps: adding a single solvent into the concentrated mother liquor for dissolving, crystallizing and drying to obtain purified phenethyl resorcinol, concentrating and crystallizing the mother liquor, and recycling the solvent. Wherein the recovered solvent in the extraction and recrystallization steps is circularly applied to the reaction step and the recrystallization step. According to the method, a solid resin catalyst with lower cost is used, continuous extraction equipment is introduced, so that the wastewater treatment cost is lower, the preparation process cost is further saved due to solvent application, and the whole process disclosed by the invention not only meets the requirements of the market on high-purity finished products, but also has important significance on large-scale synthesis and production cost control.

The invention relates to the technical field of cosmetics, in particular to a 377 soothing cosmetic preparation and application thereof.The 377 soothing cosmetic preparation is at least prepared from, by weight, 0.8-7.5 parts of a 377 wrapping composition and 0.02-5.5 parts of a soothing composition, and the 377 wrapping composition is at least prepared from phenethyl resorcinol, polyhydric alcohol and cyclodextrin; the soothing composition at least comprises dipotassium glycyrrhizinate and a radix gentianae extract, 377 is wrapped with cyclodextrin, the soothing composition is combined, the irritation problem caused by 377 is effectively inhibited and eliminated, and the irritation problem cannot be caused by adding a skin care product formula.

The invention relates to the technical field of cosmetics, in particular to a composition with a whitening effect and application thereof, and the composition is prepared from the following components in parts by weight: 0.005-1 part of tricholoma matsutake polysaccharide, 0.1-5 parts of panthenol and 1-12 parts of a whitening agent. The whitening agent is one or more of nicotinamide, tranexamic acid, ascorbic acid glucoside, undecylenoyl phenylalanine, phenylethyl resorcinol and arbutin. The whitening composition provided by the invention is not added with violating hormone components, richer intracellular and extracellular polysaccharides can be extracted from the tricholoma matsutake polysaccharides in a composite extraction mode (enzyme extraction and water extraction), the tricholoma matsutake polysaccharides with the molecular weight of 3KDa-60KDa are prepared after impurity removal and degradation treatment, and by combining panthenol and a whitening agent, the whitening effect is improved, and the whitening effect is improved. The synergistic effect shows unexpected whitening effect enhancement, the whitening speed is increased, and the composition is mild and non-irritant after being used.

This invention belongs to the field of cosmetic technology, and particularly relates to a low-melting-point solvent for paeonol used in whitening, self-microemulsion nanoparticles, their preparation method, and applications. This invention prepares a low-melting-point solvent by mixing phenylethyl resorcinol or 4-butylresorcinol with paeonol in a specific ratio. A water-soluble self-microemulsion system is constructed using DES as an oil-phase surfactant, achieving highly efficient solubilization of poorly soluble phenolic active ingredients. The active ingredients are encapsulated in the core, isolating them from water, oxygen, and light, significantly improving the stability of active ingredients such as 4-butylresorcinol and enhancing efficacy stability. When whitening active ingredients are prepared into DES, a synergistic whitening effect is observed. After being prepared into nanoparticles, transdermal absorption efficiency is significantly improved, enhancing the whitening effect. This invention effectively solves the problems of poor solubility, insufficient stability, low transdermal efficiency, and high irritation associated with phenolic whitening combinations, and is suitable for preparing highly effective, mild, and stable whitening cosmetics to meet market demands.

This invention discloses an ionic liquid transdermal delivery formulation, its preparation method, and its applications. A small molecule active substance (ILs1) is dissolved in an ionic liquid (A), and a large molecule protein substance (ILs2) is dissolved in an ionic liquid (B). ILs1 and ILs2 are then combined with a hydrogel to form the ionic liquid transdermal delivery formulation. The cation in ionic liquid A is selected from choline and its derivatives, arginine derivatives, etc., and the anion is selected from fatty acid anions, hydroxyl / carboxyl anions, etc. The small molecule active ingredient is selected from hydrolyzed sodium hyaluronate, phenylethyl resorcinol, etc. The formulation of this invention features flexible combination, high stability, good safety, and mild processing, resolving the affinity / reactivity contradiction of multiple components and the transdermal barrier of large molecules, significantly improving the transdermal efficiency of active ingredients. It can be widely used in the development of cosmetics or pharmaceuticals for skin care.

The application provides a high-performance liquid chromatography detection method for cosmetic intermediates resorcinol, ferulic acid, phenethyl resorcinol and benzoyl peroxide, which comprises the following steps: accurately weighing resorcinol, phenethyl resorcinol, benzoyl peroxide and ferulic acid standard products respectively to prepare a mixed standard solution, and precisely pipetting the mixed standard solution to obtain a series of standard working solutions by gradient concentration dilution; mixing and stirring the sample to be detected and methanol, vortexing, centrifuging, taking the supernatant, filtering, and reserving the filtrate; and injecting the standard working solution and the treated sample solution into a liquid chromatograph respectively to perform quantitative analysis and testing. The detection method is simple in operation, rapid in analysis, strong in specificity, high in separation degree, and can be used as a detection method for the four whitening components in cosmetics, thereby providing technical support for the efficacy component detection of cosmetics.

The present application relates to a kind of water-soluble whitening composition with good light stability and its preparation and application, the composition includes the following weight parts of raw material component: phenethyl resorcinol 2.5~7.5 parts, aqueous solvent 80~95 parts, pH regulator 0.005~1 part, light protection agent 1~5 parts, diglucosyl gallate 1~5 parts, sodium metabisulfite 0.1~1 part.Compared with prior art, the whitening composition of the present application can be substantially unchanged under daily irradiation, when used in whitening products etc., can provide long-lasting protection for phenethyl resorcinol.

The invention belongs to the technical field of cosmetics, and discloses a dual synergistic whitening composition containing phenylethyl resorcinol and application thereof. The composition disclosed by the invention is prepared from phenylethyl resorcinol and benzylidene dimethoxy dimethyl indanone. The composition efficiently inhibits the generation of melanin and the activity of tyrosinase through the synergistic interaction of the phenylethyl resorcinol and the benzylidene dimethoxy dimethyl indanone, the inhibition effect is obviously superior to that of a single component, and the composition shows a good whitening effect at a lower concentration, and is free of toxic and side effects. The side effect caused by high-concentration use of a single chemical component is reduced, and the safety is higher.

The invention discloses a phenylethyl resorcinol diglucoside compound as well as a preparation process and application thereof, belongs to the technical field of cosmetics, and relates to application of the phenylethyl resorcinol diglucoside compound in preparation of cosmetics. The phenethyl resorcinol diglucoside compound disclosed by the invention has the beneficial effects that the phenethyl resorcinol diglucoside compound has the effects of resisting wrinkles, tightening, relieving and whitening.

The application belongs to the technical field of cosmetics and medicine, and specifically discloses 1,3-bisbenzyl phenol compounds, a preparation method and application thereof in the preparation of whitening and anti-aging cosmetics. The application takes a diaryl heptenepolyphenol compound with alpha-glucosidase inhibition activity in sea flower as a parent, and first designs and synthesizes 4,4'-(1,3-phenylene bis(methylene)) bis 2-methyl phenol (compound 2) and 3,3'-(1,3-phenylene bis(methylene)) bis 1,2-benzene diol (compound 3). The application discloses that the compounds 1-3 have significant activity in inhibiting alpha-glucosidase and scavenging free radicals, the compound 1, i.e., 4,4'-(1,3-phenylene bis(methylene)) diphenol and the compound 2 have significant activity in inhibiting tyrosinase, the compounds have a higher cell melanin synthesis inhibition rate than a classic whitening ingredient, i.e., phenylethyl resorcinol on the market, and therefore have a good development and application prospect in the field of whitening, lightening and anti-aging cosmetics.

The invention relates to the field of cosmetics, in particular to a composition for improving the facial skin state, cosmetics and a preparation method thereof. The composition is prepared from the following components in percentage by weight: 0.01 to 2 percent of phenylethyl resorcinol, 0.01 to 20 percent of SPG beta-glucan, 0.01 to 5 percent of acetylchitosamine and 0.001 to 5 percent of a Tibetan kefir fermentation product. Phenylethyl resorcinol is compounded with SPG beta-glucan, acetylchitosamine, Tibetan kefir leavening and phenylethyl resorcinol, so that a whitening pathway can be reinforced, the skin tolerance can be improved, the skin barrier can be enhanced, and the oxidation resistance and the inflammation resistance can be enhanced; therefore, the irritation of the whole composition can be reduced, the whitening effect can be improved, the skin state can be comprehensively improved, the skin brightness can be improved, the skin redness can be reduced, and the skin wrinkles can be reduced. The phenethyl resorcinol is compounded with the SPG beta-glucan, and the acetylchitosamine is compounded with the Tibetan kefir fermentation product, so that the synergistic effect can be realized, and the problem that the action pathway of the phenethyl resorcinol is single is solved.

The invention relates to a composition with a whitening effect and application thereof, and belongs to the technical field of cosmetics. The composition with the whitening effect is prepared from the following components in parts by mass: 1 to 3 parts of phenylethyl resorcinol, 0.1 to 0.5 part of hexapeptide-2, 0.1 to 0.3 part of compound PDRN and 2 to 4 parts of nicotinamide, wherein the compound PDRN is prepared from negundo chastetree leaf PDRN, glycyrrhiza glabra PDRN and desert rose PDRN in a mass ratio of 1 to (1 to 3) to (2 to 4). The composition with the whitening effect has a remarkable effect of inhibiting tyrosinase, and is mild, non-irritant and wide in applicability.