16 results about "PHENYLETHYL RESORCINOL" patented technology

The invention discloses a composition and application thereof, and relates to the technical field of biological medicines and cosmetics. The invention specifically discloses an application of a composition comprising phenylethyl resorcinol and benzylidene dimethoxy dimethyl indanone in the aspects of oxidation resistance, light aging resistance and wrinkle resistance. The expression level of the HO-1 gene can be synergistically improved, and an excellent endogenous anti-oxidation effect is achieved; moreover, the polypeptide also has excellent tightening and anti-wrinkle effects, can synergistically improve the expression level of the COL-1 gene, inhibit the expression level of the MMP-1 gene and improve the expression level of the ELN gene especially in the aspect of UVA light aging resistance, and has the potential of being applied to cosmetics, kits and the like.

The present application relates to a kind of preparation methods of ultra-low profile thick electrolytic copper foil, comprising: i. adding composite additive in foil electrolyte, the composite additive is composed of phenylethyl resorcinol, sodium thiosulfate and diallyl disulfide;II. Adding bismuth sulfate as inorganic additive in roughening solution of surface treatment process.The ultra-low profile thick electrolytic copper foil prepared by the present application has lower surface roughness, and the actual effective copper thickness is close to the theoretical value. Under the same 2-3Oz thickness specification, the effective thickness of the copper foil is thicker than the conventional RTF copper foil. In the PCB circuit, it shows low resistance, less power consumption and better heat dissipation performance, solving the technical problems of high power loss and poor heat dissipation performance under AI high computing power.

The invention discloses a preparation method of phenylethyl resorcinol / sodium alginate emulsion gel beads as well as a product and application of the phenylethyl resorcinol / sodium alginate emulsion gel beads. The method comprises the following steps: firstly, dissolving phenethyl resorcinol in an oil phase, mixing with a water phase containing sodium alginate and a thickening agent, and homogenizing to form an oil-in-water emulsion; then, through an extrusion titration process, the emulsion is dropped into a calcium salt solution to be subjected to an ionic cross-linking reaction, and emulsion gel beads are formed through curing. According to the invention, the problems of poor water solubility, strong irritation and the like of phenylethyl resorcinol are effectively solved by utilizing an emulsion filled gel network structure, and meanwhile, the defect of unstable thermodynamics of the traditional emulsion is overcome. The prepared gel beads are high in sphericity degree, good in mechanical stability and good in mechanical property, can play a dual whitening effect by inhibiting tyrosinase activity and down-regulating protein expression of tyrosinase, and has a wide application prospect in the field of functional cosmetics.

The present application relates to a kind of organosilicon alcohol compositions and its preparation method and application, belong to medical instrument field, medical or dressing preparation field, the specific therapeutic activity of pharmaceutical preparation, the specific use or preparation manufacturing technology field of cosmetic or similar dressing preparation technical field.The organosilicon alcohol composition includes organosilicon alcohol, active ingredient and solvent;The active ingredient includes at least one of ergothioneine, retinol, glutathione, 4-butyl resorcinol, hexyl resorcinol, phenylethyl resorcinol and glabridin.The organosilicon alcohol composition provided by the present application forms complex by using organosilicon alcohol and active ingredient, constructs stable supramolecular system, greatly improves the stability of the obtained composition, and improves skin permeability, and has excellent whitening effect.

The invention relates to the technical field of cosmetics and external preparations, in particular to a phenethyl resorcinol-containing composition as well as a preparation method and application thereof. The composition containing phenylethyl resorcinol is prepared from the following raw materials in parts by mass: 0.5 to 3 parts of recombinant collagen, 0.1 to 1 part of sodium hyaluronate, 0.1 to 1 part of phenylethyl resorcinol, 0.01 to 0.1 part of glabridin, 0.2 to 1 part of beta-glucan wrapped by lipidosome, 1 to 3 parts of composite antioxidant, 0.1 to 1 part of chitosan, 0.5 to 2 parts of emulsifier, 3 to 8 parts of humectant and the balance of water, totaling 100 parts by mass. The composite antioxidant contains 40 wt% or more of shea butter modified by polyhydric alcohol, and the number-average molecular weight of the polyhydric alcohol is 50-200. Through the synergistic effect of beta-glucan and PEG modified shea butter, the transdermal absorption effect of the composition is remarkably enhanced, the blackening phenomenon of the skin is effectively improved, and the moisture content of the skin is increased.

The application relates to the cosmetic technical field, and particularly discloses a multi-channel whitening and freckle-removing compound and a preparation method thereof. In the multi-channel whitening and freckle-removing compound, the preparation raw materials comprise emollients, moisturizers, skin protectants A, antioxidants, skin protectants B, skin protectants C, a whitening composition, a composite extract and a solvent; the whitening composition comprises niacinamide; the skin protectants C comprise a phenylethyl resorcinol inclusion compound; and the composite extract comprises grape fruit cell extract and cornus officinalis extract. The multi-channel whitening and freckle-removing compound is prepared by compounding multiple functional components, synergistically acts from multiple mechanisms such as inhibiting melanin synthesis, blocking melanin transport, antioxidation and repairing skin barrier, and can realize the high-efficiency whitening and freckle-removing effect while guaranteeing the skin safety.

The invention relates to the technical field of skin care products, and discloses a whitening active component loaded mesoporous silica nanoparticle whitening essence, which comprises 5-10 parts of a functional mesoporous silica carrier, 2-8 parts of a cosolvent, 10-25 parts of a humectant, 0.1-1 part of a stabilizer, 0.1-0.5 part of a pH regulator, and 70-82 parts of water. The oil-soluble phenylethyl resorcinol / butyl resorcinol and the water-soluble alpha-arbutin are efficiently loaded through the high specific surface area and the controllable aperture structure of the functional mesoporous silica carrier, so that stable coexistence and synergistic effect of double whitening components are realized; vitamin E, ascorbyl palmitate, glutathione, amphiphilic calcium peptide and other components form a synergistic protection system, skin photoaging is delayed, skin endogenous collagen and elastic fiber regeneration is promoted, in addition, sodium hyaluronate, sodium polyglutamate and other moisturizing components can strongly lock water, and moisturizing is achieved.

The present application relates to the cosmetic technical field, especially to a kind of water-based composition containing phenethyl resorcinol and preparation method and application, the preparation raw material of the water-based composition includes: phenethyl resorcinol nano-encapsulated body, oil, water, the mass ratio of the water and oil is (4-15):1.The present application creatively uses water-oil double-layer system to solve the discoloration problem of phenethyl resorcinol, reduces the discoloration risk of phenethyl resorcinol while skin feeling is promoted and appearance is innovated, effectively solves the problem of instability of phenethyl resorcinol in aqueous system, and reduces the irritability of phenethyl resorcinol to skin.

The invention provides a low-cost preparation process for synthesizing phenylethyl resorcinol, which comprises the following steps: taking styrene and resorcinol as raw materials, taking strong-acid styrene cation exchange resin as a catalyst, and reacting at the temperature of 60-80 DEG C to obtain the phenylethyl resorcinol. The method comprises the following steps: carrying out a Friedel-Crafts alkylation reaction in a single solvent to obtain phenylethyl resorcinol, separating a reaction solution from a catalyst, introducing the obtained reaction mother liquor into continuous extraction equipment, adding water, carrying out continuous extraction, concentrating the extracted mother liquor, and purifying to obtain the phenylethyl resorcinol. The recrystallization step comprises the following steps: adding a single solvent into the concentrated mother liquor for dissolving, crystallizing and drying to obtain purified phenethyl resorcinol, concentrating and crystallizing the mother liquor, and recycling the solvent. Wherein the recovered solvent in the extraction and recrystallization steps is circularly applied to the reaction step and the recrystallization step. According to the method, a solid resin catalyst with lower cost is used, continuous extraction equipment is introduced, so that the wastewater treatment cost is lower, the preparation process cost is further saved due to solvent application, and the whole process disclosed by the invention not only meets the requirements of the market on high-purity finished products, but also has important significance on large-scale synthesis and production cost control.

This invention belongs to the field of cosmetic technology, and particularly relates to a low-melting-point solvent for paeonol used in whitening, self-microemulsion nanoparticles, their preparation method, and applications. This invention prepares a low-melting-point solvent by mixing phenylethyl resorcinol or 4-butylresorcinol with paeonol in a specific ratio. A water-soluble self-microemulsion system is constructed using DES as an oil-phase surfactant, achieving highly efficient solubilization of poorly soluble phenolic active ingredients. The active ingredients are encapsulated in the core, isolating them from water, oxygen, and light, significantly improving the stability of active ingredients such as 4-butylresorcinol and enhancing efficacy stability. When whitening active ingredients are prepared into DES, a synergistic whitening effect is observed. After being prepared into nanoparticles, transdermal absorption efficiency is significantly improved, enhancing the whitening effect. This invention effectively solves the problems of poor solubility, insufficient stability, low transdermal efficiency, and high irritation associated with phenolic whitening combinations, and is suitable for preparing highly effective, mild, and stable whitening cosmetics to meet market demands.

This invention discloses an ionic liquid transdermal delivery formulation, its preparation method, and its applications. A small molecule active substance (ILs1) is dissolved in an ionic liquid (A), and a large molecule protein substance (ILs2) is dissolved in an ionic liquid (B). ILs1 and ILs2 are then combined with a hydrogel to form the ionic liquid transdermal delivery formulation. The cation in ionic liquid A is selected from choline and its derivatives, arginine derivatives, etc., and the anion is selected from fatty acid anions, hydroxyl / carboxyl anions, etc. The small molecule active ingredient is selected from hydrolyzed sodium hyaluronate, phenylethyl resorcinol, etc. The formulation of this invention features flexible combination, high stability, good safety, and mild processing, resolving the affinity / reactivity contradiction of multiple components and the transdermal barrier of large molecules, significantly improving the transdermal efficiency of active ingredients. It can be widely used in the development of cosmetics or pharmaceuticals for skin care.

The application provides a high-performance liquid chromatography detection method for cosmetic intermediates resorcinol, ferulic acid, phenethyl resorcinol and benzoyl peroxide, which comprises the following steps: accurately weighing resorcinol, phenethyl resorcinol, benzoyl peroxide and ferulic acid standard products respectively to prepare a mixed standard solution, and precisely pipetting the mixed standard solution to obtain a series of standard working solutions by gradient concentration dilution; mixing and stirring the sample to be detected and methanol, vortexing, centrifuging, taking the supernatant, filtering, and reserving the filtrate; and injecting the standard working solution and the treated sample solution into a liquid chromatograph respectively to perform quantitative analysis and testing. The detection method is simple in operation, rapid in analysis, strong in specificity, high in separation degree, and can be used as a detection method for the four whitening components in cosmetics, thereby providing technical support for the efficacy component detection of cosmetics.

The present application relates to a kind of water-soluble whitening composition with good light stability and its preparation and application, the composition includes the following weight parts of raw material component: phenethyl resorcinol 2.5~7.5 parts, aqueous solvent 80~95 parts, pH regulator 0.005~1 part, light protection agent 1~5 parts, diglucosyl gallate 1~5 parts, sodium metabisulfite 0.1~1 part.Compared with prior art, the whitening composition of the present application can be substantially unchanged under daily irradiation, when used in whitening products etc., can provide long-lasting protection for phenethyl resorcinol.

The invention belongs to the technical field of cosmetics, and discloses a dual synergistic whitening composition containing phenylethyl resorcinol and application thereof. The composition disclosed by the invention is prepared from phenylethyl resorcinol and benzylidene dimethoxy dimethyl indanone. The composition efficiently inhibits the generation of melanin and the activity of tyrosinase through the synergistic interaction of the phenylethyl resorcinol and the benzylidene dimethoxy dimethyl indanone, the inhibition effect is obviously superior to that of a single component, and the composition shows a good whitening effect at a lower concentration, and is free of toxic and side effects. The side effect caused by high-concentration use of a single chemical component is reduced, and the safety is higher.

The invention discloses a phenylethyl resorcinol diglucoside compound as well as a preparation process and application thereof, belongs to the technical field of cosmetics, and relates to application of the phenylethyl resorcinol diglucoside compound in preparation of cosmetics. The phenethyl resorcinol diglucoside compound disclosed by the invention has the beneficial effects that the phenethyl resorcinol diglucoside compound has the effects of resisting wrinkles, tightening, relieving and whitening.

The invention relates to a composition with a whitening effect and application thereof, and belongs to the technical field of cosmetics. The composition with the whitening effect is prepared from the following components in parts by mass: 1 to 3 parts of phenylethyl resorcinol, 0.1 to 0.5 part of hexapeptide-2, 0.1 to 0.3 part of compound PDRN and 2 to 4 parts of nicotinamide, wherein the compound PDRN is prepared from negundo chastetree leaf PDRN, glycyrrhiza glabra PDRN and desert rose PDRN in a mass ratio of 1 to (1 to 3) to (2 to 4). The composition with the whitening effect has a remarkable effect of inhibiting tyrosinase, and is mild, non-irritant and wide in applicability.