Composition with whitening effect as well as preparation method and application thereof

Abstract

The invention provides a composition with a whitening effect as well as a preparation method and application thereof. The composition comprises the following raw materials in percentage by mass: 2-10% of polyhydric alcohol; 2-15% of grease; 0.1-1% of a thickening agent; 0.1-2% of an emulsifier; 1-5% of nicotinamide; 0-3% of 3-o-ethyl ascorbic acid; 0 to 0.4 percent of phenylethyl resorcinol; 0 to 1% of alpha-arbutin; 0-0.5% of a plant whitening compound II; 10% to 0.5% of nonapeptide-10%; 0 to 0.5% of tocopheryl acetate; 0 to 0.5 percent of inositol; 0-0.5% of a purslane extract; 0 to 0.5 percent of bisabolol; and the balance water. According to the composition with the whitening effect, through synergistic interaction of multiple components, the whitening effect is good, and meanwhile, the composition has the anti-allergy and soothing effects.

Description

Technical Field

[0001] The invention belongs to the technical field of cosmetics, and specifically relates to a composition with whitening effect, a preparation method and application thereof. Background Art

[0002] Whitening products are an important category in the cosmetics industry. They are designed to help reduce skin pigmentation, brighten skin tone, improve dullness, and fight spots and marks after sunburn. The existing whitening and spot-lightening products have an efficacy mechanism of inhibiting the production of melanocytes and the transfer of melanin to the epidermis. This is the main mechanism of action of whitening and spot-lightening products. There is no absorption and anti-oxidation effect. A lot of whitening ingredients are added, but they are not absorbed, resulting in waste. Too many whitening ingredients are added, causing irritation and prone to allergies. Summary of the invention

[0003] The purpose of the present invention is to provide a composition with whitening effect and a preparation method and application thereof.

[0004] In order to achieve the above object, the present invention provides the following technical solutions: A composition with whitening effect comprises the following raw materials in percentage by mass: 2-10% polyol; 2-15% oil; 0.1-1% thickener; 0.1-2% emulsifier; 1-5% niacinamide; 0-3% 3-o-ethyl ascorbic acid; 0-0.4% phenylethyl resorcinol; 0-1% α-arbutin; 0-0.5% plant whitening compound-II; 0-0.5% nonapeptide-10; 0-0.5% tocopherol acetate; 0-0.5% inositol; 0-0.5% purslane extract; 0-0.5% bisabolol; and the balance is water.

[0005] Furthermore, the invention comprises the following raw materials in percentage by weight: 7% polyol; 9% oil; 0.5% thickener; 1.5% emulsifier; 3% niacinamide; 2% 3-o-ethyl ascorbic acid; 0.2% phenylethyl resorcinol; 0.6% α-arbutin; 0.3% plant whitening compound-II; 0.3% nonapeptide-1; 0.4% tocopherol acetate; 0.2% inositol; 0.5% purslane extract; 0.2% bisabolol; and the balance is water.

[0006] Furthermore, the preparation method of the purslane extract is: (1) Grinding dried purslane to a particle size of 100-200 mesh to obtain powder; (2) adding 10-13 parts by weight of water and 0.1-0.13 parts by weight of Lactobacillus plantarum to 1 part by weight of the powder, performing anaerobic fermentation at a temperature of 32-35° C. for 13-15 hours, and sterilizing to obtain a first fermentation product; (3) adding 0.15-0.17 parts by weight of Lactobacillus helveticus to the first fermentation product for anaerobic fermentation at a temperature of 32-35° C. for 7-9 hours, and sterilizing to obtain a second fermentation product; (4) Filtering the second fermentation product through a 0.22 μm filter membrane to obtain a filtrate, and concentrating and drying the filtrate to obtain a purslane extract.

[0007] Furthermore, the Lactobacillus plantarum has a deposit number of CCTCC AB 2010210 and is deposited in China Center for Type Culture Collection.

[0008] Furthermore, the preservation number of Lactobacillus helveticus is: CCTCCAB2010205; it is preserved in the China Center for Type Culture Collection.

[0009] Furthermore, the preparation method of plant whitening compound-II is: (1) Mix dried Pyracantha fruit, Sophora flavescens, Lycium barbarum, and Osmanthus fragrans, and grind to a particle size of 200-300 mesh to obtain a mixed powder; (2) adding 10-12 parts by weight of water and 0.1-0.12 parts by weight of cellulase to 1 part by weight of the mixed powder, performing anaerobic fermentation at a temperature of 30-35° C. for 10-12 hours, and sterilizing to obtain a first enzymatic hydrolysis product; (3) adding 0.15-0.17 parts by weight of neutral protease to the first enzymatic hydrolysis product for anaerobic fermentation at a temperature of 30-35° C. for 10-12 h, and sterilizing to obtain a second enzymatic hydrolysis product; (4) Filter the second enzymatic hydrolysis product through a 0.22 μm filter membrane to obtain a filtrate, and concentrate and dry the filtrate to obtain the plant whitening compound-II.

[0010] Furthermore, the mass ratio of Pyracantha fortuneana, Sophora flavescens, Lycium barbarum, and Osmanthus fragrans is 10:(2-4):(5-7):(13-16).

[0011] Furthermore, the enzymatic activity of the cellulase is 10,000-20,000 U / g; the enzymatic activity of the neutral protease is 10,000-20,000 U / g.

[0012] The method for preparing the composition with whitening effect of the present invention comprises the following steps: (1) Add water, thickener, polyol and niacinamide to the emulsifier and heat to 85±1℃ to dissolve and keep warm for 30-40 minutes; (2) Add oil and homogenize for 5-15 minutes. During homogenization, add emulsifier and tocopherol acetate. After homogenization, stir and keep warm for 5 minutes to cool down. (3) Stirring and cooling to 60±1°C, add phenylethyl resorcinol, 3-o-ethyl ascorbic acid, α-arbutin and inositol; (4) Stir and cool to 45±1°C, add plant whitening compound-II, nonapeptide-1, purslane extract and bisabolol; (5) Stir and cool to 34±1℃, take samples for inspection, and discharge the material if qualified; (6) After standing for 24 hours and passing the inspection, the products are divided and packaged, inspected again, and put into storage.

[0013] Phenylethyl resorcinol: On the one hand, it has a strong inhibitory effect on tyrosinase; on the other hand, the bisphenol hydroxyl structure in the structure of this ingredient has a strong antioxidant capacity, which can inhibit the reaction of melanin production; it reduces the production of melanin by downregulating the expression of MITF protein and its downstream tyrosinase-related proteins TRP1 and TRP2; it has an inhibitory effect on the enzyme catalysis process and is a tyrosinase inhibitor; and it has an antioxidant effect.

[0014] o-Ethyl Ascorbic Acid: It penetrates the stratum corneum directly to the basal melanocytes, inhibits tyrosinase activity, inhibits the formation of melanin, and reduces melanin to colorless state, thus effectively whitening the skin.

[0015] Niacinamide: It is a derivative of vitamin B3, which can inhibit the formation of melanin particles; inhibit the transfer of melanin to keratinocytes; accelerate the transfer of melanin in keratinocytes to the stratum corneum and promote the shedding of the stratum corneum.

[0016] α-Arbutin: It is a tyrosinase inhibitor. It can effectively inhibit the activity of tyrosinase without affecting the cell proliferation concentration. It competes with tyrosinase for the binding site of DOPA by directly binding to it, blocking the synthesis of DOPA and DOPAquinone, thereby interfering with melanocytes and inhibiting the production of melanin. At the same time, it also has the function of diluting the formed melanin, accelerating the decomposition and excretion of melanin, reducing skin pigmentation, and removing spots and freckles.

[0017] Plant Whitening Compound-II: Contains four plant extracts: 1. Pyracantha fruit is the king of micro-fruits, rich in various vitamins and flavonoids, with antioxidant, tyrosinase inhibition, melanin reduction and pigmentation improvement effects; 2. The main components of Sophora flavescens are flavonoids and alkaloids. In addition to having multiple pharmacological abilities, studies have confirmed that matrine has the effect of inhibiting tyrosinase activity and melanin production; 3. Ningxia wolfberry ranks among the top in China in terms of efficacy and nutritional value. Studies have confirmed that wolfberry polysaccharides have the effects of scavenging free radicals, significant antioxidant activity and anti-aging; 4. Osmanthus fragrans is rich in minerals, vitamins, Osmanthus fragrans amino acids and other moisturizing ingredients, which enhance the skin's moisturizing ability.

[0018] Nonapeptide-1: Nonapeptide-1 competitively antagonizes the binding of the natural ligand a-MSH to its receptor MC1R, thereby blocking the activation of tyrosinase, reducing melanin production, and preventing excessive melanin production.

[0019] Tocopherol acetate: As an important free radical scavenger, it can directly provide hydrogen atoms to superoxide free radicals, combine with free radicals in the body, reduce oxidative damage caused by superoxide free radicals, prevent cells from being oxidized, and aggravate skin pigmentation. Antioxidants are also skin conditioners; they can prevent excessive oxygen free radicals caused by external factors such as sunlight, ultraviolet rays, and air pollution, and play a protective role in delaying photoaging, preventing sunburn, inhibiting the formation of sunburn erythema, and preventing skin damage.

[0020] Inositol: A natural osmotic regulator molecule that uses the principle of osmotic pressure protectant to protect cells in high and low osmotic pressure environments without hindering the normal metabolic activities of cells. By adjusting the intracellular osmotic pressure to compensate for the solute concentration, the osmotic pressure is adjusted in both directions, allowing the water content in the cells to return to normal.

[0021] Portulaca oleracea extract: rich in polysaccharides, flavonoids, alkaloids and other compounds with broad-spectrum antibacterial properties, it has certain anti-inflammatory and anti-allergic effects, can reduce inflammation-related cytokines, reduce or inhibit the irritation of common allergens to the skin, weaken skin inflammatory responses, and at the same time enhance the skin's barrier function.

[0022] Bisabolol: has anti-inflammatory properties and has also been shown to have antibacterial activity, anti-irritant effects, skin protective effects, and repair effects.

[0023] The invention provides an application of a composition with whitening effect.

[0024] The bacteria and enzymes used in the present invention are all commercially available products.

[0025] Compared with the prior art, the advantages and beneficial effects of the present invention are: 1. Three core key preparations: (I) Tyrosinase inhibitors: niacinamide, phenylethyl resorcinol, α-arbutin, nonapeptide-1, 3-O-ethyl ascorbic acid, plant whitening compound-II (II) Melanin reducing agent: 3-O-ethyl ascorbic acid (III) Melanosome transport inhibitor: niacinamide.

[0026] 2. Antioxidant mechanism and synergistic whitening: Tocopherol acetate can directly provide hydrogen atoms to superoxide radicals, combine with free radicals in the body, reduce oxidative damage caused by superoxide radicals, prevent cells from being oxidized, and aggravate skin pigmentation; cooperate with various whitening ingredients to create a full whitening channel. Promote the absorption system channel: Using the characteristics of inositol to promote penetration, in the whitening system, it can promote whitening ingredients to enter the skin more easily and exert corresponding effects. Portulaca oleracea extract + bisabolol classic combination, reduce irritation, protect the skin, and enhance the skin barrier function.

[0027] 3. The present invention uses 6 whitening ingredients to synergistically create whitening effects: niacinamide, 3-o-ethyl ascorbic acid, phenylethyl resorcinol, α-arbutin, plant whitening compound-II, and nonapeptide-1; tocopherol acetate directly provides hydrogen atoms to superoxide radicals, combines with free radicals in the body, reduces oxidative damage caused by superoxide radicals, prevents cells from being oxidized and aggravates skin pigmentation to achieve antioxidant synergistic whitening effects; inositol improves whitening effects by promoting absorption; purslane extract and bisabolol achieve all-round protection by soothing and anti-inflammatory.

[0028] 4. The present invention uses microbial fermentation and enzymolysis technology in the preparation method of purslane extract and plant whitening compound-II. Such a treatment method can improve the bioavailability of the effective ingredients in the raw materials and produce new biologically active substances, thereby enhancing its whitening effect and skin soothing performance. The addition of plant lactobacillus and helveticus in the preparation of purslane extract can degrade the macromolecular substances in purslane through the anaerobic fermentation process, and convert them into small molecules that are more easily absorbed by the skin. In addition, the lactic acid, short-chain fatty acids and other metabolites produced in the lactic acid bacteria fermentation process have antioxidant, anti-inflammatory and moisturizing effects, which help to improve skin health and whitening effects.

[0029] The preparation of plant whitening compound-II and the application of cellulase and neutral protease can decompose the cellulose and protein in Pyracantha fortuneana, Sophora flavescens, Lycium barbarum, and Osmanthus fragrans, releasing more bioactive ingredients such as polyphenols, flavonoids, amino acids, etc. These ingredients have the functions of anti-oxidation, inhibiting melanin production and regulating immune response, which are helpful for whitening and anti-allergy.

[0030] Through the action of microorganisms and enzymes, the concentration of antioxidants, anti-inflammatory factors and whitening active ingredients in the extract can be increased. These ingredients can directly or indirectly inhibit the activity of tyrosinase and reduce the synthesis of melanin, thereby achieving a whitening effect. Promote skin cell renewal: Certain metabolites such as lactic acid can accelerate the metabolism of the skin's stratum corneum, promote the shedding of dead skin cells, make the skin smoother and more delicate, and help whiten the skin.

[0031] The various metabolites produced during the fermentation and enzymatic hydrolysis process have anti-inflammatory and antioxidant effects, which can reduce inflammation and damage to the skin caused by external factors such as ultraviolet rays and pollution, thereby soothing sensitive skin. Moisturizing factors such as lactic acid and short-chain fatty acids produced during the fermentation process can enhance the skin's barrier function, prevent water loss, keep the skin moisturized, and help repair damaged skin tissue. DETAILED DESCRIPTION

[0032] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0033] The raw materials used in the present invention are all commercially available without special restrictions: The polyol is propylene glycol; The oil is grape seed oil; The thickener is xanthan gum; The emulsifier is glyceryl stearate.

[0034] Example 1 The present embodiment provides a composition with whitening effect, comprising the following raw materials in percentage by mass: 7% polyol; 9% oil; 0.5% thickener; 1.5% emulsifier; 3% niacinamide; 2% 3-o-ethyl ascorbic acid; 0.2% phenylethyl resorcinol; 0.6% α-arbutin; 0.3% plant whitening compound-II; 0.3% nonapeptide-1; 0.4% tocopherol acetate; 0.2% inositol; 0.5% purslane extract; 0.2% bisabolol; and the balance water.

[0035] The preparation method of the purslane extract is: (1) Grinding dried purslane to a particle size of 100-200 mesh to obtain powder; (2) adding 12 parts by weight of water and 0.12 parts by weight of Lactobacillus plantarum to 1 part by weight of the powder, performing anaerobic fermentation at a temperature of 34° C. for 14 hours, and sterilizing to obtain a first fermentation product; (3) adding 0.16 parts by weight of Lactobacillus helveticus to the first fermentation product for anaerobic fermentation at a temperature of 34° C. for 8 h, and sterilizing to obtain a second fermentation product; (4) Filtering the second fermentation product through a 0.22 μm filter membrane to obtain a filtrate, and concentrating and drying the filtrate to obtain a purslane extract.

[0036] The preservation number of Lactobacillus plantarum is CCTCC AB 2010210, and it is preserved in China Center for Type Culture Collection.

[0037] The preservation number of Lactobacillus helveticus is: CCTCC AB 2010205; it is preserved in the China Center for Type Culture Collection.

[0038] The preparation method of plant whitening compound-II is: (1) Mix dried Pyracantha fruit, Sophora flavescens, Lycium barbarum, and Osmanthus fragrans, and grind to a particle size of 200-300 mesh to obtain a mixed powder; (2) adding 11 parts by mass of water and 0.11 parts by mass of cellulase to 1 part by mass of the mixed powder, performing anaerobic fermentation at a temperature of 33° C. for 11 h, and sterilizing to obtain a first enzymatic hydrolysis product; (3) adding 0.16 parts by weight of neutral protease to the first enzymatic hydrolysis product for anaerobic fermentation at a temperature of 32° C. for 11 h, and sterilizing to obtain a second enzymatic hydrolysis product; (4) Filter the second enzymatic hydrolysis product through a 0.22 μm filter membrane to obtain a filtrate, and concentrate and dry the filtrate to obtain the plant whitening compound-II.

[0039] The mass ratio of Pyracantha fortuneana, Sophora flavescens, Lycium barbarum and Osmanthus fragrans is 10:3:7:15.

[0040] The enzymatic activity of the cellulase is 10,000 U / g; the enzymatic activity of the neutral protease is 20,000 U / g.

[0041] The method for preparing the composition with whitening effect is characterized by comprising the following steps: (1) Add water, thickener, polyol and niacinamide to the emulsifier and heat to 85℃ to dissolve and keep warm for 35 minutes; (2) Add oil and homogenize for 10 minutes. During homogenization, add emulsifier and tocopherol acetate. After homogenization, stir and keep warm for 5 minutes to cool down. (3) Cooling to 60°C with stirring, adding phenylethyl resorcinol, 3-o-ethyl ascorbic acid, α-arbutin and inositol; (4) Stir and cool to 45°C, then add plant whitening compound II, nonapeptide-1, purslane extract and bisabolol; (5) Stir and cool to 34°C, take samples for inspection, and discharge the material if qualified; (6) After standing for 24 hours and passing the inspection, the products are divided and packaged, inspected again, and put into storage.

[0042] Example 2 The present embodiment provides a composition with whitening effect, comprising the following raw materials in percentage by mass: 2% polyol; 10% oil; 0.1% thickener; 2% emulsifier; 1% niacinamide; 3% 3-o-ethyl ascorbic acid; 0.4% phenylethyl resorcinol; 1% α-arbutin; 0.2% plant whitening compound-II; 0.1% nonapeptide-1; 0.5% tocopherol acetate; 0.5% inositol; 0.2% purslane extract; 0.1% bisabolol; and the balance water.

[0043] The preparation method of the purslane extract is: (1) Grinding dried purslane to a particle size of 100-200 mesh to obtain powder; (2) adding 10 parts by weight of water and 0.13 parts by weight of Lactobacillus plantarum to 1 part by weight of the powder, conducting anaerobic fermentation at a temperature of 32° C. for 15 hours, and sterilizing to obtain a first fermentation product; (3) adding 0.15 parts by weight of Lactobacillus helveticus to the first fermentation product for anaerobic fermentation at a temperature of 32° C. for 9 h, and sterilizing to obtain a second fermentation product; (4) Filtering the second fermentation product through a 0.22 μm filter membrane to obtain a filtrate, and concentrating and drying the filtrate to obtain a purslane extract.

[0044] The preservation number of Lactobacillus plantarum is CCTCC AB 2010210, and it is preserved in China Center for Type Culture Collection.

[0045] The preservation number of Lactobacillus helveticus is: CCTCC AB 2010205; it is preserved in the China Center for Type Culture Collection.

[0046] The preparation method of plant whitening compound-II is: (1) Mix dried Pyracantha fruit, Sophora flavescens, Lycium barbarum, and Osmanthus fragrans, and grind to a particle size of 200-300 mesh to obtain a mixed powder; (2) adding 12 parts by mass of water and 0.1 parts by mass of cellulase to 1 part by mass of the mixed powder, performing anaerobic fermentation at a temperature of 35° C. for 10 hours, and sterilizing to obtain a first enzymatic hydrolysis product; (3) adding 0.17 parts by weight of neutral protease to the first enzymatic hydrolysis product for anaerobic fermentation at a temperature of 30° C. for 12 h, and sterilizing to obtain a second enzymatic hydrolysis product; (4) Filter the second enzymatic hydrolysis product through a 0.22 μm filter membrane to obtain a filtrate, and concentrate and dry the filtrate to obtain the plant whitening compound-II.

[0047] The mass ratio of Pyracantha fortuneana, Sophora flavescens, Lycium barbarum and Osmanthus fragrans is 10:2:5:13.

[0048] The enzymatic activity of the cellulase is 20,000 U / g; the enzymatic activity of the neutral protease is 10,000 U / g.

[0049] The method for preparing the composition with whitening effect is characterized by comprising the following steps: (1) Add water, thickener, polyol and niacinamide to the emulsifier and heat to 85℃ to dissolve and keep warm for 30 minutes; (2) Add oil and homogenize for 5 minutes. During homogenization, add emulsifier and tocopherol acetate. After homogenization, stir and keep warm for 5 minutes to cool down. (3) Cooling to 60°C with stirring, adding phenylethyl resorcinol, 3-o-ethyl ascorbic acid, α-arbutin and inositol; (4) Stir and cool to 45°C, then add plant whitening compound II, nonapeptide-1, purslane extract and bisabolol; (5) Stir and cool to 34°C, take samples for inspection, and discharge the material if qualified; (6) After standing for 24 hours and passing the inspection, the products are divided and packaged, inspected again, and put into storage.

[0050] Comparative Example 1 The difference between this comparative example and Example 1 is: a composition with whitening effect, comprising the following raw materials in mass percentage: 7% polyol; 9% oil; 0.5% thickener; 1.5% emulsifier; 0.5% niacinamide; 0.5% 3-o-ethyl ascorbic acid; 1.2% phenylethyl resorcinol; 1.6% α-arbutin; 0.3% plant whitening compound-II; 11.3% nonapeptide-1; 0.4% tocopherol acetate; 0.2% inositol; 0.5% purslane extract; 0.7% bisabolol; and the balance water.

[0051] Comparative Example 2 The difference between this comparative example and Example 1 is: a composition with whitening effect, comprising the following raw materials in mass percentage: 7% polyol; 9% oil; 0.5% thickener; 1.5% emulsifier; 3% niacinamide; 2% 3-o-ethyl ascorbic acid; 0.2% phenylethyl resorcinol; 0.6% α-arbutin; 0.3% nonapeptide-1; 0.4% tocopherol acetate; 0.2% inositol; 0.8% purslane extract; 0.2% bisabolol; and the balance water.

[0052] Comparative Example 3 The difference between this comparative example and Example 1 is: a composition with whitening effect, comprising the following raw materials in mass percentage: 7% polyol; 9% oil; 0.5% thickener; 1.5% emulsifier; 3% niacinamide; 2% 3-o-ethyl ascorbic acid; 0.2% phenylethyl resorcinol; 0.6% α-arbutin; 0.8% plant whitening compound-II; 0.3% nonapeptide-1; 0.4% tocopherol acetate; 0.2% inositol; 0.2% bisabolol; and the balance water.

[0053] Comparative Example 4 The difference between this comparative example and Example 1 is that the purslane extract is a commercially available product from Shaanxi Junhe Biotechnology Co., Ltd.

[0054] Comparative Example 5 The difference between this comparative example and Example 1 is that the plant whitening compound-II is a mixture of Pyracantha fortuneana fruit extract, Sophora flavescens extract, Ningxia wolfberry extract, and Ophiopogon japonicus extract in a mass ratio of 10:3:7:15. Pyracantha fortuneana fruit extract, Sophora flavescens extract, Ningxia wolfberry extract, and Ophiopogon japonicus extract are all purchased from Shaanxi Junhe Biotechnology Co., Ltd.

[0055] Performance Testing The compositions of Examples 1-2 and Comparative Examples 1-5 were subjected to performance tests.

[0056] 70 male test subjects aged 30-40 with dull skin and acne scars were randomly selected and divided into 7 groups. The same area of ​​the test subject's face was selected as the test area. The composition was used every night. No other cosmetics could be used on the test area during the test period. The test was continued for 2 months. The average melanin value of the test area was tested using a skin melanin and hemoglobin tester on the 0th, 30th and 60th day of use. The smaller the value, the less melanin content. The results are shown in Table 1.

[0057] Table 1 Performance test results

[0058] As can be seen from the above performance test results, the whitening effect of embodiment 1-2 is good, and especially the comprehensive performance of embodiment 1 is the most outstanding, which is mainly because of the result of the synergistic compounding of each component. The present invention uses microbial fermentation and enzymolysis technology in the preparation method of purslane extract and plant whitening compound-II, and such a treatment method can improve the bioavailability of effective ingredients in the raw materials, and simultaneously produce new bioactive substances, thereby enhancing its whitening effect and skin soothing performance. The addition of plant lactobacillus and helveticus in the preparation of purslane extract, through the anaerobic fermentation process, can degrade the macromolecular substances in purslane, so that it is converted into small molecules that are more easily absorbed by the skin. In addition, the lactic acid, short-chain fatty acids and other metabolites produced in the lactic acid bacteria fermentation process have antioxidant, anti-inflammatory and moisturizing effects, which help to improve skin health and whitening effect.

[0059] However, the comparative example does not adopt the necessary technical solution, resulting in its performance being significantly worse than that of the embodiment in the corresponding performance test. The above experimental results further prove the importance of the technical solution defined in the present invention to its technical effect.

[0060] The above is a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A composition having whitening effect, characterized in that: The invention comprises the following raw materials in mass percentage: polyol 2-10%; oil 2-15%; thickener 0.1-1%; emulsifier 0.1-2%; niacinamide 1-5%; 3-o-ethyl ascorbic acid 0-3%; phenylethyl resorcinol 0-0.4%; α-arbutin 0-1%; plant whitening compound-II 0-0.5%; nonapeptide-10-0.5%; tocopherol acetate 0-0.5%; inositol 0-0.5%; purslane extract 0-0.5%; Bisabolol 0-0.5%; water, balance.

2. The composition having whitening effect according to claim 1, characterized in that: The invention comprises the following raw materials in percentage by weight: 7% polyol; 9% oil; 0.5% thickener; 1.5% emulsifier; 3% niacinamide; 2% 3-o-ethyl ascorbic acid; 0.2% phenylethyl resorcinol; 0.6% α-arbutin; 0.3% plant whitening compound-II; 0.3% nonapeptide-1; 0.4% tocopherol acetate; 0.2% inositol; 0.5% purslane extract; 0.2% bisabolol; and the balance is water.

3. The composition with whitening effect according to claim 1, characterized in that: The preparation method of the purslane extract is: (1) Grinding dried purslane to a particle size of 100-200 mesh to obtain powder; (2) adding 10-13 parts by weight of water and 0.1-0.13 parts by weight of Lactobacillus plantarum to 1 part by weight of the powder, performing anaerobic fermentation at a temperature of 32-35° C. for 13-15 hours, and sterilizing to obtain a first fermentation product; (3) adding 0.15-0.17 parts by weight of Lactobacillus helveticus to the first fermentation product for anaerobic fermentation at a temperature of 32-35° C. for 7-9 hours, and sterilizing to obtain a second fermentation product; (4) Filtering the second fermentation product through a 0.22 μm filter membrane to obtain a filtrate, and concentrating and drying the filtrate to obtain a purslane extract.

4. The composition having whitening effect according to claim 3, characterized in that: The preservation number of Lactobacillus plantarum is CCTCC AB 2010210, and it is preserved in China Center for Type Culture Collection.

5. The composition with whitening effect according to claim 3, characterized in that: The preservation number of Lactobacillus helveticus is: CCTCC AB 2010205; it is preserved in the China Center for Type Culture Collection.

6. The composition having whitening effect according to claim 1, characterized in that: The preparation method of plant whitening compound-II is: (1) Mix dried Pyracantha fruit, Sophora flavescens, Lycium barbarum, and Osmanthus fragrans, and grind to a particle size of 200-300 mesh to obtain a mixed powder; (2) adding 10-12 parts by weight of water and 0.1-0.12 parts by weight of cellulase to 1 part by weight of the mixed powder, performing anaerobic fermentation at a temperature of 30-35° C. for 10-12 hours, and sterilizing to obtain a first enzymatic hydrolysis product; (3) adding 0.15-0.17 parts by weight of neutral protease to the first enzymatic hydrolysis product for anaerobic fermentation at a temperature of 30-35° C. for 10-12 h, and sterilizing to obtain a second enzymatic hydrolysis product; (4) Filter the second enzymatic hydrolysis product through a 0.22 μm filter membrane to obtain a filtrate, and concentrate and dry the filtrate to obtain the plant whitening compound-II.

7. The composition having whitening effect according to claim 6, characterized in that: The mass ratio of Pyracantha fortuneana, Sophora flavescens, Lycium barbarum, and Osmanthus fragrans is 10:(2-4):(5-7):(13-16).

8. The composition with whitening effect according to claim 6, characterized in that: The enzymatic activity of the cellulase is 10,000-20,000 U / g; the enzymatic activity of the neutral protease is 10,000-20,000 U / g.

9. A method for preparing the composition with whitening effect according to any one of claims 1 to 8, characterized in that: The following steps are involved: (1) Add water, thickener, polyol and niacinamide to the emulsifier and heat to 85±1℃ to dissolve and keep warm for 30-40 minutes; (2) Add oil and homogenize for 5-15 minutes. During homogenization, add emulsifier and tocopherol acetate. After homogenization, stir and keep warm for 5 minutes to cool down. (3) Stirring and cooling to 60±1°C, add phenylethyl resorcinol, 3-o-ethyl ascorbic acid, α-arbutin and inositol; (4) Stir and cool to 45±1°C, add plant whitening compound-II, nonapeptide-1, purslane extract and bisabolol; (5) Stir and cool to 34±1℃, take samples for inspection, and discharge the material if qualified; (6) After standing for 24 hours and passing the inspection, the products are divided and packaged, inspected again, and the finished products are put into storage.

10. Use of the composition with whitening effect according to any one of claims 1 to 8.

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