24results about How to "Reduce oxidative damage" patented technology

The present invention provides a high-protein bio-fermented aquatic feed and a preparation method thereof. The aquatic feed comprises the following raw materials in parts by weight: 20-30 parts of imported fish meal, 10-15 parts of compound minerals, 5-10 parts of bioactive peptides, 5-10 parts of lysine, 5-10 parts of compound trace elements, 3-8 parts of compound vitamins, 3-6 parts of herbal extracts, 2-5 parts of compound probiotics, 2-4 parts of immune polysaccharides, and 1-3 parts of compound enzymes; the herbal extracts are prepared by fermenting astragalus membranaceus, isatis root, liquorice root, calotropis gigantea, ventilago leiocarpa benth, clove, rhizoma chuanxiong, and galangal officinale. By organically integrating imported fish meal, astaxanthin-peptide chelate, herbal extracts, compound immune polysaccharides, compound probiotics and various nutrients, the present invention realizes the synergistic effect of "promoting feeding - enhancing digestion - strengthening liver and gall - enhancing immunity - resisting stress - inhibiting bacteria - stabilizing water quality", significantly improves the growth rate, survival rate and comprehensive breeding benefit of crustacean aquatic animals, and has good economic value and application prospect.

The invention discloses application of ginseng leaf polysaccharide in relieving fish quality decline caused by water hypoxia, and belongs to the technical field of aquatic product culture. The ginseng leaf polysaccharide is applied to relieving fish quality decline caused by water hypoxia for the first time, and by adding the ginseng leaf polysaccharide, the problems of fish muscle oxidative damage, poor texture property, low nutritional value and the like caused by hypoxia stress can be effectively improved; the invention provides a new relieving technology for improving fish quality decline caused by hypoxia in culture, provides technical support for improving fish quality of cultured fishes under intensive culture conditions, improves freshwater fish culture benefits, and solves the problem of lack of a safe and reliable method for relieving fish quality decline caused by hypoxia in a water body at present.

The invention discloses a TSS-SBFO coating agent for storage and preservation of perishable fruits and a preparation method of the TSS-SBFO coating agent. The coating agent prepared from the sphaeros gum, the artemisia desertorum gum, the silk fibroin peptide, the sea buckthorn fruit oil and the glycerol can be used for storage and preservation of perishable fruits, and has good oxidation resistance. The coating agent prepared by the invention can be directly coated on the surfaces of perishable fruits in a soaking manner, the use method is simple, good light transmittance can be maintained while the ultraviolet transmittance is reduced, and the effects of keeping fresh, resisting oxidation and maintaining a good state of the fruits can be achieved.

This invention relates to the field of biomedical technology, specifically to nanoparticles for treating retinal ischemia-reperfusion injury, their preparation method, pharmaceutical composition, and uses. The nanoparticles consist of a zeolite imidazole ester-8 core encapsulating baicalin and a polydopamine shell coating its surface, prepared via in-situ self-polymerization. The nanoparticles utilize the polydopamine shell to scavenge reactive oxygen species and prolong intraocular residence time, while their core responsively degrades in a weakly acidic pathological microenvironment, precisely releasing baicalin, thereby synergistically exerting antioxidant, anti-inflammatory, and anti-apoptotic effects. Experiments show that these nanoparticles can effectively reduce oxidative damage and inflammation in the model retina, significantly inhibit ganglion cell apoptosis, and restore electroretinogram function, providing a novel multi-target therapeutic strategy for retinal ischemic diseases.

The invention discloses a muscle anti-aging composition with spermidine combined with a wolfberry aqueous extract and application of the muscle anti-aging composition, and belongs to the technical field of application of bioactive substances. The composition is prepared by compounding spermidine and a Chinese wolfberry aqueous extract according to a specific ratio, and the Chinese wolfberry aqueous extract is prepared by an optimized aqueous extraction process, so that core active ingredients are reserved to a greater extent. The optimal mass ratio of spermidine to the wolfberry aqueous extract is 1: 2. Through a synergistic effect mechanism, the antioxidant capacity of senescent muscle cells is remarkably improved, and the muscle cell oxidative stress and senescence process induced by D-galactose is effectively inhibited. The composition is simple in preparation process and safe in components, can be widely applied to the fields of food, health care products and medicines, and provides a new solution for developing efficient and natural muscle anti-aging products.

This invention belongs to the field of fiber material technology, and relates to a composite fiber containing nano-natural tea fiber, its preparation method, and its application. The raw materials for preparing the composite fiber include nano-natural tea fiber and basic fiber pulp, wherein the nano-natural tea fiber is a yerba mate nanofiber microemulsion. This invention integrates nanotechnology into the preparation of natural tea fiber. The microemulsion method allows for the simultaneous and uniform dispersion of multiple effective components from tea leaves in the yerba mate nanofiber microemulsion, effectively showcasing the multifunctionality of the fabric. The microemulsion system exhibits high uniformity and long-term stability, eliminating the need for additional surfactants during spinning to achieve high dispersion of the nano-tea fiber in the spinning solution, ensuring the long-lasting effectiveness of the resulting functional fabric. Furthermore, yerba mate contains abundant tea polyphenols and unique yerba mate alkaloids, which further enhance the overall performance of the composite fiber.

The invention discloses a compound probiotic preparation for relieving heat stress of sows and application of the compound probiotic preparation, and belongs to the technical field of animal feed. The compound probiotic preparation comprises clostridium butyricum, bacillus subtilis, bacillus licheniformis and enterococcus faecalis, wherein the final concentration of the clostridium butyricum in the feed is 1 * 10 < 6 > CFU / g, and the final concentration of the bacillus subtilis, the final concentration of the bacillus licheniformis and the final concentration of the enterococcus faecalis in the feed is 5 * 10 < 6 > CFU / g. The preparation provided by the invention can effectively reduce the stress hormone level and oxidative damage index in the blood of the sow under the heat stress condition, improve the activity of antioxidant enzyme, improve the feed intake and lactation performance in the lactation period, and reduce the backfat loss. Meanwhile, through the vertical transfer effect of the sows and the piglets, the intestinal morphology of the offspring piglets is remarkably improved, the intestinal barrier function and the antioxidant capacity are enhanced, and the weaning weight and the average daily gain of the piglets are improved, so that the negative effects of heat stress on the reproductive performance of the sows and the growth of the piglets are comprehensively relieved. The preparation is green and safe, and has important application value.

This invention discloses a facial mask containing natural agarwood extract and its preparation method. The mask comprises the following raw materials in parts by weight: 5-10 parts agarwood extract, 1-5 parts wheat germ extract, 2-5 parts tremella extract, 1-4 parts superoxide dismutase, and 0.5-4.5 parts Bacillus fermentation product. This facial mask possesses the ability to synergistically scavenge ABTS free radicals and synergistically promote the production of type III collagen. On the one hand, it reduces oxidative damage at the source, slowing down the aging process; on the other hand, the production of type III collagen repairs and regenerates the skin, making it firmer and more elastic. The facial mask of this invention synergistically enhances the skin barrier from different aspects, achieving a better synergistic beauty effect. Furthermore, the facial mask of this invention also has good brightening, soothing, and calming effects, and is safe, effective, natural, and low-irritant.

This invention discloses an intelligent programmed engineered probiotic system and its preparation method. The system uses probiotic strains as the engineered substrate bacteria, and is constructed by integrating the coding genes for superoxide dismutase (SOD), antimicrobial peptides (AMP), and a synchronized cleavage circuit (SLC) with the probiotic strains through genetic engineering technology. This invention also discloses a pH-responsive genetically engineered bacterial microsphere containing the aforementioned intelligent programmed engineered probiotic system, which is encapsulated in a carrier formed by the cross-linking reaction of sodium alginate and calcium chloride ions. The intelligent programmed engineered probiotic system and the accompanying pH-responsive genetically engineered bacterial microspheres constructed in this invention, through the synergistic design of the dual-function therapeutic modules SOD and AMP, and the programmed cleavage circuit SLC, simultaneously address the three core problems of IBD: oxidative stress, dysbiosis, and intestinal barrier damage.

This invention discloses a strain of *Bosea vestrisii* and its application in promoting plant growth and improving salt tolerance. This strain is deposited at the China Center for Type Culture Collection (CCTCC) under accession number CCTCC M 2026307. *Bosea vestrisii* exhibits strong salt tolerance and possesses multiple growth-promoting functions, including secreting indoleacetic acid (IAA), synthesizing extracellular polysaccharides, and biological nitrogen fixation. Experiments show that applying this strain to wheat roots significantly increases plant height, root length, and biomass under salt stress, and enhances the activity of antioxidant enzymes (such as catalase, peroxidase, and superoxide dismutase) in the plant, effectively alleviating oxidative damage caused by salt stress. This invention provides a highly efficient and environmentally friendly microbial resource for improving saline-alkali soils, enhancing crop stress tolerance, and achieving sustainable agriculture.

The application discloses a kind of biological active peptide capable of improving sea cucumber summer passing capacity and its preparation method and application.The biological active peptide is obtained by extracting, enzyme hydrolysis, separation and purification using tuna meat as raw material, and the amino acid sequence of the active peptide is MADFFTRL.Test shows that the biological active peptide can improve the survival rate of sea cucumber under high temperature stress, enhance the activities of SOD, CAT and other antioxidant enzymes, reduce the content of MDA, reduce the oxidative damage caused by high temperature, thereby improving the heat resistance and safe summer passing capacity of sea cucumber.The biological active peptide can be used for preparing sea cucumber feed additive or functional feed, and has good application prospect.

The invention discloses preparation of an immobilized material based on phosphate solubilizing bacteria and application of the immobilized material in soil, and belongs to the technical field of soil remediation microbial agents. The material takes bacillus megatherium and lignin as core functional components, and takes a mixed system of sodium alginate and sodium carboxymethyl cellulose as a carrier. The immobilized material is high in mechanical strength, good in stability and excellent in mass transfer efficiency, meanwhile, insoluble phosphorus is activated through metabolites secreted by bacillus megatherium, and the content of available phosphorus in soil is increased. The material can also improve the soil structure, improve the cation exchange capacity and the organic matter content, enhance the activities of peroxidase and superoxide dismutase of the rice, reduce the content of malonaldehyde, relieve oxidative damage caused by Cd stress, reduce Cd accumulation of the rice from the source and guarantee normal growth of the rice.

The present application relates to the field of microbial technology, and specifically discloses a lactobacillus plantarum DT55 and its application in preparing products with micro-plastic adsorption and removal functions.A new lactobacillus plantarum (Lactiplantibacillus plantarum) DT55 is developed, and the preservation number is GDMCC No:63623.The strain can adsorb micro-plastics, accelerate the discharge of plastics in the body, reduce the micro-plastic residues in the intestinal tract of mice, reduce the oxidative damage caused by micro-plastic accumulation, and reduce the inflammatory response caused by micro-plastics, and is expected to be developed into a probiotic product to protect human health.

This invention relates to the field of tea cultivation technology, and more particularly to a cultivation method for improving tea quality using corn syrup. It includes the following steps: (1) planting asexual tea seedlings in containers filled with cultivation substrate and cultivating them in a greenhouse; (2) applying nutrient solution every 6-8 days during cultivation; (3) continuing cultivation until the tea seedlings sprout in early spring, and then spraying them with corn syrup solution. This invention, through foliar spraying with 0.5 mL / L corn syrup, significantly promotes tea growth and photosynthetic efficiency, improves tea quality, and under drought stress conditions, CSL0.5 treatment makes the tea leaves greener and more upright, enhancing the drought resistance of the tea trees.

The invention discloses an active peptide capable of directionally inducing IPSCS cracking, a preparation method of the active peptide and application of the active peptide in a preparation for repairing liver injury. Experiments prove that the active peptide provided by the invention has a remarkable protective effect on a liver injury model induced by cyclophosphamide and shows a definite anti-oxidative stress effect. The result shows that a key path of chemotherapy injury can be intervened from the source by simulating or enhancing an endogenous protection mechanism of the liver. Compared with the existing exogenous synthetic drugs or single-component natural products, the product provided by the invention has the potential advantages of more comprehensive action mechanism and better biogenic property. Meanwhile, the extract is derived from directionally differentiated functional cells, and a brand new thought and material basis are provided for developing a novel chemotherapy liver protective agent which does not affect the chemotherapy curative effect and has good biocompatibility.

The invention discloses a Mongolian horse semen cryoprotectant as well as a preparation method and application thereof, and belongs to the technical field of semen cryopreservation. The Mongolian horse semen freezing protection liquid comprises a dilution liquid I and a dilution liquid II, the preparation method specifically comprises the following steps: (1) preparing a basic diluent; (2) preparing centrifugal yolk liquid; (3) preparing a diluted liquid I; and (4) preparing a diluted liquid II. On the basis of an INRA82 basic formula, L-proline is added as an antioxidant, so that the oxidative stress resistance of sperms in the freezing process is improved, and the total activity and integrity of the frozen sperms are improved. The method is easy and convenient to operate, low in cost and suitable for Mongolian horse germplasm resource protection and large-scale propagation application.

This invention relates to the field of sweet potato monoembryonic seed germination technology, specifically a sweet potato monoembryonic seed initiator and its application method. The seed initiator is composed of the following components at various concentrations: manganese-doped nano-ferric oxide 50-200 mg / L, trehalose 300-600 mg / L, glutathione 20-100 mg / L, potassium nitrate 0.5-2 g / L, and fullerol 10-50 mg / L. The seed initiator used in this invention has a significant promoting effect on the germination of sweet potato monoembryonic seeds. Its manganese-doped nano-ferric oxide content has a wide applicable concentration range, making it easy to prepare. Furthermore, the manganese-doped nano-ferric oxide can be recovered through magnetic separation for multiple uses, reducing usage costs.

The invention provides a biological organic fertilizer containing a compound strain as well as a preparation method and application of the biological organic fertilizer, and belongs to the technical field of biological organic fertilizers. The bacillus velezensis and the bacillus amyloliquefaciens are added, the bacillus velezensis can tolerate certain salinity and alkalinity, the soil fertility can be improved through nitrogen fixation, the utilization rate of phosphorus can be improved by dissolving inorganic phosphorus, the tolerance of plants to environmental stress is enhanced through iron-producing carriers, the growth of seedlings is promoted, and the growth and development of the plants are promoted; the bacillus amyloliquefaciens has the functions of resisting salt and alkali to a certain degree, dissolving phosphorus, dissolving potassium and the like. The bio-organic fertilizer disclosed by the invention is beneficial to remarkably increasing the contents of chlorophyll, proline and soluble sugar of the pakchoi and also reducing the content of malondialdehyde of the pakchoi, so that the oxidative damage of plants is reduced, the stress resistance and quality are improved, the contents of nitrogen, phosphorus and potassium in soil are integrally improved, and the acidification of the soil is remarkably relieved.

The application belongs to the technical field of cosmetic raw material preparation, and particularly relates to a preparation method of tuberose solid flower wax composite coated microcapsules, a product thereof and application. The application adopts an integrated process of plant oil coupling extraction, low-temperature crystallization purification combined with composite coating modification and low-temperature spray drying. The process condition of the application is mild, more natural active substances in the tuberose flower wax are retained, the prepared product has excellent antioxidant and anti-inflammatory activities, can effectively scavenge free radicals, reduce skin oxidative damage and inhibit the secretion of inflammatory factors, and has high skin care safety. Meanwhile, the problems of poor water solubility of natural flower wax, weak system adaptability and difficulty in application in water-based skin care products are solved, and the defects of active ingredient loss, low product purity and solvent residue in the traditional process are effectively made up.

The application provides application of a thirteen-peptide in preparation of a product for improving cognitive impairment. The thirteen-peptide with an amino acid sequence shown in SEQ ID NO: 1 can effectively relieve oxidative damage, inhibit iron deposition, restore mitochondrial function, regulate neurotrophic factor expression, relieve nerve cell damage through multiple targets, and further effectively improve cognitive impairment.

The invention provides a broiler chicken raising method based on nutrition regulation and environmental stress induction, and belongs to the technical field of livestock breeding, and the broiler chicken raising method comprises the following steps: dividing a raising cycle into four stages of 1-14 days old, 15-28 days old, 29-35 days old and 36-45 days old according to time, and performing nutrition regulation and environmental induction on the four stages, feed containing flaxseed meal and fish oil is fed at the 29-35-day-old stage, choline and betaine are added, periodic mild cold stress treatment is combined, and unsaturated fatty acid is promoted to be deposited into muscles; 80% limited feeding is carried out at the 36-45-day-old stage, meanwhile, a yeast extract, L-glutamine and a flavor enhancer composed of betaine and allicin are supplemented, the content of flavor substances such as inosinic acid and glutamic acid is effectively increased, and the flavor of the broiler chickens is remarkably improved. Meanwhile, muscle fibers are refined and oxidative damage is relieved by reducing the feeding density, adjusting illumination, prolonging the free-ranging time and the like.

This application discloses a composition and its preparation and application of permeation-enhancing liposomes, belonging to the field of cosmetic production technology. The technical solution is as follows: a composition composed of Forsythia suspensa extract, Lysimachia christinae extract and Sophora flavescens root extract, wherein the mass ratio of Forsythia suspensa extract, Lysimachia christinae extract and Sophora flavescens root extract is 2-8:0.5-3:2-6. The composition provided by this application can scavenge free radicals and reduce oxidative damage. In the experiment, the above substances produced a good synergistic effect when used in combination.

The invention provides a fungus and actinomycete complex microbial inoculant for preventing and treating root rot. The complex microbial inoculant contains spiropolyspora rosea with the preservation number of CGMCC (China General Microbiological Culture Collection Center) No.42332 and streptomyces taenanensis with the preservation number of CGMCC No.36965. The invention further provides a preparation method of the fungus and actinomycete complex microbial inoculant. The invention also provides an application of the fungus and actinomycete complex microbial inoculant. The complex microbial inoculant provided by the invention contains fermentation products of spiropolyspora roseus HLY-1 and streptomyces talanigerum NYC 1-5, the two fermentation products have no inhibition effect, and a synergistic effect can be generated by mixed application of the two fermentation products.

The invention discloses a marker for identifying the quality of camellia oleifera seeds. The research identifies potential markers for oxidation and rancidity in the oil tea seed storage process, including oxidized lipid, triglyceride and volatile compounds, and these findings provide a solid theoretical basis for formulating a strategy for effectively relieving lipid oxidative damage. The research result of the invention not only provides a scientific basis for storage, preservation and quality control of the camellia oleifera seeds, but also contributes to sustainable development of the camellia oleifera industry.