217 results about "Free radical scavenger" patented technology

The instant invention pertains to a method and a fluid composition for producing contact lenses with relatively high edge quality and with relatively high precision and fidelity in reproducing a desired lens design. The method of the invention involves: a mold which has a first mold half with a first molding surface and a second mold half with a second molding surface, wherein the first and second mold halves are configured to receive each other such that the cavity is formed between the first and second molding surfaces which define the opposite two surfaces of a contact lens to be produced; a spatial limitation of actinic radiation to define the edge of the contact lens to be produced; and addition of a radical scavenger in a fluid composition comprising a lens-forming material to reduce substantially the crosslinking / polymerizing, caused by diffused, scattered and / or reflected incident actinic radiation, of the fluid composition outside of and around the spatial limitation of actinic radiation.

Disclosed is a combination of hydrofluoroolefins and / or hydrochlorofluoroolefins with stabilizers wherein the stabilizers minimize the degradation of the hydrofluoroolefins and hydrochlorofluoroolefins during storage, handling and use yet allow for atmospheric degradation. The combinations exhibit low or zero ozone depletion potential and lower global warming potential making them of interest as replacements for chlorofluorocarbons and hydrfluorocarbons. The combinations of the present invention comprise hydrofluoroolefins and / or hydrochlorofluoroolefins in combination with a stabilizer or stabilizers selected from free radical scavengers, acid scavengers, oxygen scavengers, polymerization inhibitors and combinations thereof.

A method of inactivating microorganisms such as viruses within a fluid such as a biological fluid is disclosed. The method includes the steps of providing a UV reactor, which may take the form of an elongated generally annular reaction chamber surrounding at least one elongated UV lamp, moving the fluid within the reaction chamber in a primary flow directed along the length of the UV lamp, and inducing a circulating secondary flow within the fluid with the secondary flow being superimposed on the primary flow. As the fluid moves through the reaction chamber in the primary flow, it is circulated repeatedly toward and away from the UV lamp in the circulating secondary flow to provide uniform and controllable exposure of the entire volume of fluid to ultraviolet radiation. Microorganisms such as viruses are thus inactivated while desirable components in the fluid, such as proteins, are preserved without the use of a free radical scavenger.

The invention relates to viral formulations and related pharmaceutical products for use in gene therapy and / or vaccine applications. Especially preferred viral formulations disclosed herein are liquid adenovirus formulations, which show improved stability when stored in about the 2-8° C. range while also being compatible with parenteral administration. These formulations comprise a buffer, a sugar, a salt, a divalent cation, a non-ionic detergent, as well as a free radical scavenger and / or a chelating agent to inhibit free radical oxidation.

Methods and compositions for preventing oxidative damage to proteins, particularly antibodies, are provided. The compositions include a combination of metal chelators, such as DTPA, EGTA, and / or DEF, and can further include one or more free radical scavengers, particularly scavengers of oxygen radicals. Methods for enhancing protein stability using the compositions of the invention are also disclosed.

The present invention is; (a) a process for stabilizing a cyclotetrasiloxane, such as 1,3,5,7-tetramethylcyclotetrasiloxane, against polymerization used in a chemical vapor deposition process for silicon oxides in electronic material fabrication comprising providing an effective amount of a neutral to weakly acidic polymerization inhibitor to such cyclotetrasiloxane; and (b) a composition of a cyclotetrasiloxane, such as 1,3,5,7-tetramethylcyclotetrasiloxane, stabilized against polymerization used in a chemical vapor deposition process as a precursor for silicon oxides in electronic material fabrication, comprising; such cyclotetrasiloxane and a neutral to weakly acidic polymerization inhibitor. A free radical scavenger can also be included in the process and composition.

Various embodiments of the present invention include implantable medical devices such as stents manufactured from polymers, and more particularly, biodegradable polymers including biodegradable polyesters. Other embodiments include methods of fabricating implantable medical devices from polymers. The devices and methods utilize one or more stabilizers, where each stabilizer may be chosen from the following categories: free radical scavengers, peroxide decomposers, catalyst deactivators, water scavengers, and metal scavengers.

The present invention relates to a method of hair colouring and bleaching compositions providing a composition comprising i) at least one source of peroxymonocarbonate ions, ii) at least one alkalizing agent, preferably a source of ammonium ions, and iii) at least one radical scavenger, wherein said composition has a pH of up to 9.5, and applying the composition to the hair and retaining on the hair for a period of less than 20 minutes, which provide a high level of lift and lightening and the required dye deposition and grey coverage whilst reducing the concentration of peroxide, the ammonia odour and reducing the hair fibre damage.

The invention relates to viral formulations and related pharmaceutical products for use in gene therapy and / or vaccine applications. Especially preferred viral formulations disclosed herein are liquid adenovirus formulations, which show improved stability when stored in about the 2-8° C. range while also being compatible with parenteral administration. These formulations comprise a buffer, a sugar, a salt, a divalent cation, a non-ionic detergent, as well as a free radical scavenger and / or a chelating agent to inhibit free radical oxidation.

A dietary supplement system includes a dietary supplement composition for oral administration by an individual in the morning, the composition, including (a) a telomere maintenance complex including: Purslane extract (aerial parts); Turmeric rhizome extract (95% curcuminoids); Quercetin dehydrate, Cayenne pepper fruit; Vanadium (as vanadyl sulfate); Fenugreek seed; Astragalus root extract, Omega fatty acid complex including linoleic acid; alpha-linolenic acid; oleic acid borage seed oil gamma-linolenic acid), evening primrose oil fish body oil (eicosapentaenoic acid; docosahexaenoic acid); (b) a calorie restriction mimetics and gene expression complex including Trans-resveratrol (from Polygonum cuspidatum root extract); Pterostilbene Fisetin 50% (Buxus microphlla Sieb (stem and leaf; Alpha lipoic acid, Coenzyme Q-10, Betaine HCl, Sulfur (from methylsulfonylmethane); L-Carnitine tartrate; L-Carnitine HCl, and (c) a free radical scavenger complex, including Green tea leaf extract catechin and polyphenols); Anthocyanins (from bilberry fruit and grape skin extracts).

A nutritional supplement for the prevention and treatment of excessive intestinal permeability is provided. The treatment includes a dietary regimen of nutritional buffers, amino acid chelates, minerals and vitamins. Other components may include antioxidants, free radical scavengers, beneficial organisms, and intestinal tract-soothing herbs.

A method and apparatus for recycling and recovering potentially explosive solvents includes providing a contaminated solvent to a distillation tank, vaporizing the solvent in the distillation tank, thereby producing solvent vapor, condensing the solvent vapor, and adding a free radical scavenger substance to the distillation tank during the heating step. The vapor is then condensed and collected in a clean solvent tank where additional free radical scavenger substance is added to the clean solvent tank. Preferably, contaminated solvent is introduced into the solvent recovery system by providing contaminated solvent into contaminated solvent tank which is connected to the distillation tank, and an oxygen displacer substance is provided to the contaminated solvent tank and the clean solvent tank so as to minimize the amount of free oxygen in the tanks.

Procedures and methods for synthesizing biodegradable polymer coated nanoceria result in stable nanoparticle preparations in aqueous systems and physiological relevant colloidal solutions, such as phosphate buffer saline. The coated nanoceria preparations increase the nanoparticle concentration in aqueous or colloidal solutions as most needed for antioxidant, free-radical scavenger, and autocatalytic biomedical applications, including, biological, pharmacological and potential clinical use. To meet this need, a facile synthetic procedure for preparation of a biodegradable polymer-coated nanoceria is disclosed; the preferred biodegradable polymer is dextran. The synthesis method occurs under ambient conditions in an aqueous phase without the use of surfactants and results in a monodispersed preparation that is dextran-coated as determined by dynamic light scattering (DLS). Preliminary characterization of polymer coated nanoceria by XPS, TEM, XRD, and the like shows that these nanoparticles have the necessary physical properties for the desired biological potency, such as Ce+4 / Ce+3 mixed valence state.

The invention discloses a PE wood / plastic composite sectional material and relates to the technical field of composite materials. The PE wood / plastic composite sectional material is made from the following raw materials in parts by weight: 10-70 parts of wood flour, 20-50 parts of polyethylene, 3-20 parts of calcium carbonate powder or talc powder, 0.1-1 part of stearic acid or n-butyl stearate, 0.4-1.5 parts of one or a combination of more than one of calcium stearate, lead stearate, barium stearate, cadmium stearate, lanthanum stearate, zinc stearate, PE wax, or oxidized polyethylene wax OPE or 0.1-1.5 parts of paraffin, 0.5-3 parts of a coupling agent, 0.5-2 parts of an antioxidant, 0.05-2 parts of a UV absorbent, a light shielding agent, quencher or free radical scavenger, and 3-12 parts of titanium pigment. The PE wood / plastic composite sectional material provided by the invention has the advantages of water resistance, insect resistance, rust corrosion resistance, convenience for fabrication, safety in use, strong plasticity, energy conservation, environmental friendliness and no formaldehyde, benzene or other poisonous substances.

Disclosed is a combination of hydrofluoroolefins and / or hydrochlorofluoroolefins with stabilizers wherein the stabilizers minimize the degradation of the hydrofluoroolefins and hydrochlorofluoroolefins during storage, handling and use yet allow for atmospheric degradation. The combinations exhibit low or zero ozone depletion potential and lower global warming potential making them of interest as replacements for chlorofluorocarbons and hydrfluorocarbons. The combinations of the present invention comprise hydrofluoroolefins and / or hydrochlorofluoroolefins in combination with a stabilizer or stabilizers selected from free radical scavengers, acid scavengers, oxygen scavengers, polymerization inhibitors and combinations thereof.

The present invention is; (a) a process for stabilizing a cyclotetrasiloxane, such as 1,3,5,7-tetramethylcyclotetrasiloxane, against polymerization used in a chemical vapor deposition process for silicon oxides in electronic material fabrication comprising providing an effective amount of a free radical scavenger polymerization inhibitor to such cyclotetrasiloxane; and (b) a composition of a cyclotetrasiloxane, such as 1,3,5,7-tetramethylcyclotetrasiloxane, stabilized against polymerization used in a chemical vapor deposition process as a precursor for silicon oxides in electronic material fabrication, comprising; such cyclotetrasiloxane and a free radical scavenger polymerization inhibitor.

Described herein is a composition that comprises a cryoprotectant; a membrane protectant that stabilizes or assists in stabilization of membranes of sperm; and a free radical scavenger (e.g., a reducing agent, an antioxidant).

The invention relates to an iron super-micro particle preparation technique, belongs to radiation chemical nanometer material production technique. The technique of the invention is that: nanometer material preparation: obtain iron hydroxide colloid solution by using iron sulfate as raw material and ammonia liquor as precipitant; control the crystal core accumulating speed and the particle size by hydrophilic surface-activator polyvinyl alcohol with isopropyl alcohol as free radical scavenger and in radiation chemistry principles; develop the radiation chemical reaction by the bunch of electrons generated by industrial electron accelerator; the radiated solution produces nanometer triple iron quadoxide which deoxidated with high purity hydrogen to obtain nanometer iron powder. The advantages of the invention are that: simple technical processes, short production cycle, non-pollution, the obtained particles are of uniform diameter and finely divided. The nanometer iron produced in above ways is of higher satiating hard magnetism and coercive force which is applicable on high intensity magnetic recording material..

The invention relates to polyamide moulded masses based on semi-crystalline, transparent copolyamides predominantly based on aliphatic monomers, for producing transparent or pigmentable moulded parts with a high level of flexibility, high notch-impact strength (Charpy), low water absorbency and excellent resistance to chemicals, containing between 40 and 100 wt. % of at least one transparent copolyamide (constituent A) with a maximum glass transition temperature (Tg) of 80 DEG C and a melting temperature of at least 150 DEG C, and a melting enthalpy of at least 20 J / g, preferably at least 30 J / g, consisting of at least two different diamines selected from the group consisting of linear and / or branched-chain aliphatic diamines with between 9 and 14 carbon atoms and cycloaliphatic diamines, especially between 6 and 36 carbon atoms, the concentration of cycloaliphatic diamine being between 10 and a maximum of 40 mol % and the concentration of aliphatic diamine at least 60 mol %, respectively in relation to the total diamine content, and of at least one aliphatic dicarboxylic acid, especially between 6 and 36 carbon atoms, and between 0 and 60 wt. % of at least one other polymer (constituent B) selected from the group consisting of amorphous or semi-crystalline homopolyamides or copolyamides, polyether ester amides, polyether amides, polyester amides or mixtures thereof, between 0 and 10 wt. % of other additives (constituent C) selected from the group consisting of UV stabilisers, heat stabilisers, free-radical scavengers and / or processing auxiliary agents, inclusion inhibitors, lubricants, mould-release auxiliary agents, softeners, functional additives for influencing optical properties, especially the refractive index, impact-resistant modifiers, nanoscale fillers and / or loaders, optical brighteners, dyes or mixtures thereof, the constituents (A), (B) and (C) amounting to 100 wt. %.

The invention discloses a new clause of a five membered heterocylic ring compounds of general formula I and its pharmaceutically or cosmetically acceptable salts, wherein R1, R2, R3, R4, R5, A, B, X and Y are as defined in the specification. The invention also discloses a process for preparation of these compound and their therapeutic and cosmetic applications particularly in the management of aging related and diabetic vascular complications. The compounds in question act by triple action of an AGE (Advanced Glycation Endproducts) breaker, AGE inhibitor and free radical scavenger which make them most suitable in different therapeutic and cosmetic applications. The invention also discloses pharmaceuticals and cosmetic compositions comprising these compounds and method of treatment of diseases caused by accumulation of AGE and / or free radicals in the body cells.

The present invention encompasses a liquid bioartificial tissue for restoring tissue and organ function to an injured or damaged organ in a human subject. The liquid bioartificial tissue is injected into a target organ and can significantly restore organ function within two weeks. The invention also encompasses a cell culture medium comprising ascorbic acid (or other free-radical scavengers and / or anti-oxidants) that is used for pre-treating transplantable cells prior to organ transplantation. Pre-treatment with ascorbic acid increases transplanted cell viability and colonization by nearly fifty-fold compared with untreated cells. The invention is particularly useful for treating ischemic heart damage following myocardial infarction.

A hydrogen peroxide composition comprises hydrogen peroxide, a stabilizer system comprising a colloidal stannate, at least one acidifying agent or a salt thereof selected from the group consisting of sulfur-containing acidifying agents, nitric acid, and mixtures and salts thereof. Optionally, the hydrogen peroxide composition comprises an organic phosphonic acid or a salt thereof, such as amino-phosphonate, and / or a free radical scavenger, such as salicylic acid. A cleaning formulation comprises the hydrogen peroxide composition, a pH adjusting agent, and optionally other additives, such as surfactants. The cleaning formulation may be made by mixing the hydrogen peroxide or a precursor thereof, water, colloidal stannate, and at least one acidifying agent, and optionally, adjusting the pH to achieve an alkaline pH.

The present invention discloses a continuous carbon fiber reinforced nylon composite material used under a continuous high temperature environment, and a preparation method thereof. The continuous carbon fiber reinforced nylon composite material comprises, by weight, 100 parts of a nylon resin, 5-150 parts of continuous carbon fibers, 1-15 parts of a compatibilizing agent, 0.1-3 parts of an antioxidant, 0.03-2 parts of an organic copper salt compound, 0.1-3 parts of a free radical scavenger, 0.05-2 parts of an anti-hydrolysis agent, and 0.1-5 parts of a lubricant. The preparation method comprises: adopting nylon, a compatibilizing agent, an additive for inhibiting high temperature oxidation degradation, and the like, carrying out melt extrusion through an extruder, and carrying out complete impregnating on continuous carbon fibers through an impregnating machine head to prepare the continuous carbon fiber reinforced nylon composite material. According to the present invention, the material has characteristics of super high comprehensive mechanical property, good size stability, permanent antistatic property, electromagnetic wave shielding, and small friction coefficient, wherein mechanical property retention rate after continuous use for 4000 h under a 160 DEG C high temperature environment is more than 85%.

The present invention relates to hair colouring and bleaching compositions comprising i) at least one source of peroxymonocarbonate ions, ii) at least one alkalizing agent, preferably a source of ammonium ions, and iii) at least one radical scavenger, wherein said composition has a pH of up to 9.5, which provide a high level of lift and lightening and the required dye deposition and grey coverage whilst reducing the concentration of peroxide, the ammonia odour and reducing the hair fibre damage.

Cold storage solutions for the preservation of organs and biological tissues prior to implantation, including a cellular energy production stimulator under anaerobic conditions, an anti-inflammatory agent, and an oxygen free radical scavenger.

The present invention discloses a detoxification agent for vomitoxin in a biodegradable feed and a preparation technology thereof. The detoxification agent comprises the following raw materials: 40-60 parts of bentonite, 20 parts of immune polysaccharides, 10-20 parts of a free radical scavenger, and 20-30 parts of a vomitoxin degrading bacillus subtilis powder agent. A preparation method of the bacillus subtilis powder agent comprises the following steps: 1) original strains are subjected to a seed liquid activation and a mother culture is conducted in a primary fermentation tank loaded with a culture medium; 2) a mother culture liquid is subjected to an amplification culture in a second fermentation tank loaded with a LB culture medium; and 3) the bacterium body and the fermentation liquid are separated, the separated fermentation liquid is concentrated, and the concentrated fermentation liquid is dried to prepare the vomitoxin degrading bacillus subtilis powder agent; and the powder agent is combined with the two raw material mixtures in the above parts by weight to obtain the finished products. The detoxification agent has the degradation rate of the vomitoxin at 95% or more, is high in degradation efficiency, and avoids the defects of adsorbents. Besides, the immune polysaccharides and free radical scavenging components are added in the products, so that the detoxification agent can play the functions of protecting liver and improving the immunity of body, and is obvious in effects.

The invention relates to a health product, in particular to a soft capsule and a method for producing the same. The soft capsule is characterized in that: the soft capsule contains water soluble pearl powder, selenium-enriched yeast, natural vitamin E, beeswax, glycerol monostearate, span-80 and corn oil. The soft capsule is a powerful antioxidant which can effectively improve the rancidity of fatty acid in food and the alimentary tract, and protect cells from being damaged by harmful matters generated by oxidation of unsaturated fatty acid; the soft capsule is an extremely good free radical scavenger which can protect biological membranes from being attacked by free radicals, effectively resist ageing nutrients, improve immunity of a human body, keep the integrity of red blood cells and promote the biological synthesis of the red blood cells; the soft capsule is an indispensible promoting factor for cellular respiration, which can protect the lung tissue from air pollution; moreover, the soft capsule also can prevent the over-aggregation of blood platelets, avoid the increase of lipid peroxidation in the blood, prevent cardiovascular diseases and supplementing calcium element in the human body.

Bio-decomposable polymer composition shows good thermal decomposition, wherein a drop of weight-average molecular controls within 30% of the initial after treatment of molding and radial sterilization, by adding free radical scavenger to the bio-decomposable polymer, in order to resolve the problem. Bio-decomposable polymer composition of the invention, standing thermal and radial decompositions is possibly applied for medical and many other industrial uses. Moreover, this processing method is applied for non-bio-decomposable polymer fields such as nylon or polypropylene for sterilization of thermal casting and irradiation.