72 results about "Acidifying agents" patented technology

The disclosure relates to compositions, including ready-to-use spray or wipe compositions, that are non-toxic, non-corrosive, biodegradable acidic antimicrobial compositions that exhibit broad-spectrum antimicrobial efficacy, wherein the compositions comprise an amine oxide, such as an alkyl amine oxide, in combination with an acidulant. Beneficially, the acidic antimicrobial compositions are capable of achieving at least a 3-log microbial reduction within 5 minutes under relatively mild pH conditions. The compositions provide cleaning and sanitizing.

The invention belongs to the technical field of coatings, and particularly relates to polyester resin for a powder coating as well as a preparation method and application of the polyester resin. The polyester resin for the powder coating is prepared from the following raw materials: polyol, polyacid, polyamide acid oligomer and an acidifying agent. The polyamide acid oligomer is introduced in the synthesis of the polyester resin, an amide structure in the polyamide acid oligomer can improve the electrification property of polyester, the improvement of the electrification property is beneficial to improving the powdering rate of powder, and meanwhile, an N-H bond in the amide structure has relatively strong polarity and hydrogen-bond interaction; the wettability of the base material is obviously improved through the synergistic effect of the two. Therefore, the polyamide acid oligomer is introduced into the polyester resin and is combined with other components, so that the corner coverage rate of the powder coating can be obviously increased.

This invention belongs to the field of bile acid detection technology, and discloses a sample pretreatment method for determining the content of bile acid subtypes and its application. The pretreatment method includes the following steps: S1, acidifying the sample to be tested with an acidifying agent to a pH of 2-4 to obtain an acidified sample; S2, eluting the acidified sample onto a mixed-mode anion exchange column to obtain an eluent; S3, evaporating the eluent and reconstituted with a rehydration solution to obtain the test sample. The test sample obtained by this pretreatment method can effectively eliminate or compensate for matrix interference when used for targeted analysis of bile acid subtypes by LC-MS / MS, thus effectively improving detection sensitivity.

The application relates to the field of food, and discloses a low-fat high-protein stretch type cheese and a preparation method thereof. The preparation method comprises the following steps: subjecting raw milk to standardization treatment to obtain a standardized liquid; subjecting the standardized liquid to sterilization treatment to obtain a sterilized product; uniformly mixing the sterilized product with konjac glucomannan after cooling to obtain a mixture; adjusting the pH value of the mixture to 5.8-6.0 by using an acidifying agent to obtain an acidified liquid; inoculating the acidified liquid with a starter to perform pre-fermentation treatment to obtain a pre-fermented product; performing curd formation treatment, whey discharge treatment, heap fermentation treatment, salting treatment, hot stretching treatment and ripening treatment on the pre-fermented product to obtain the low-fat high-protein stretch type cheese. The stretch type cheese disclosed by the application not only has low fat content and high protein content, but also has excellent melting property, stretchability and flavor taste, is comparable to traditional high-fat cheese, and meets the needs of consumers.

The invention relates to a composite acidifying agent for improving feed intake of lactating sows and a preparation method thereof, and belongs to the technical field of feed additives. The composite acidifier comprises a wall material and a core material, wherein the wall material comprises cystine-gamma-polyglutamic acid and arginine-chitosan; the core material comprises organic acid, organic acid salt and fermentation liquor. According to the compound acidifying agent disclosed by the invention, the cystine cross-linked gamma-polyglutamic acid and the arginine grafted chitosan are used as wall materials, and the microcapsule with an intestinal targeted release function is formed by wrapping the organic acid, so that the utilization efficiency of the acidifying agent and the feed intake of lactating sows can be effectively improved.

The invention belongs to the crossing field of fine chemical engineering, crystal engineering and continuous production technologies, and particularly relates to a process and a device for continuously preparing 1, 3-cyclohexanedione crystals. The method comprises the following steps: respectively introducing a pre-cooled 1, 3-cyclohexanedione monosodium salt aqueous solution and an acidifying agent into a static mixer through a metering pump for mixing, introducing the materials into an aging tank for aging, and carrying out solid-liquid separation on the aged materials to obtain 1, 3-cyclohexanedione crystals. The invention provides a process and a device for continuously preparing a 1, 3-cyclohexanedione crystal, the process and the device are a brand-new continuous acidification crystallization process and system based on a static mixer, and aims to fundamentally eliminate local supersaturation, realize accurate control of the crystal form and morphology of 1, 3-cyclohexanedione and produce a high-quality flaky crystal form product. And the continuity, the stabilization and the high efficiency of the production process are realized.

This invention relates to the field of operation and maintenance service management technology, and discloses a method and system for operation and maintenance service management of biogas slurry resource utilization, including: Step 1, establishing batch sampling and actual measurement, establishing a plot table, and obtaining nitrogen deficit; Step 2, calculating volume, intensity, and acidification dosage according to the parameter table, locking the process, and generating a prescription list; Step 3, using capacity and safety margin constraints for loading, segmenting by particle size, calculating weights, and locking the scheduling table; Step 4, acidifying and mixing thoroughly and verifying to the target pH, weighing and verifying again upon delivery, issuing a metering slip and shipping; Step 5, retesting pH and ammonia nitrogen to verify the prescription, and if qualified, the on-site parameters are read-only; Step 6, applying at a constant rate according to the prescription, reconciling dual-track metering, and recording faults for exceeding tolerances; Step 7, calculating the loss rate based on delivery, dual-track, and on-site actual measurement, comparing with thresholds for correction, and calculating the achievement rate of the three items. This invention realizes deterministic scheduling, unified metering standards, and traceable closed-loop management of biogas slurry throughout the entire process from delivery to soil application.

The invention relates to a synthesis method of sulfopropionic anhydride. The synthesis method comprises the following steps: (1) mixing 3-bromopropionic acid and sodium sulfite in water, and carrying out sulfonation reaction to obtain a mixture; (2) mixing the mixture with an acidifying agent, and carrying out acidification reaction to obtain 3-sulfonyl propionic acid; and (3) mixing the 3-sulfonyl propionic acid with a dehydrating agent and an organic solvent, and carrying out a dehydration reaction to obtain the sulfopropionic anhydride. According to the invention, compounds such as 3-bromopropionic acid and sodium sulfite are used as reaction raw materials to prepare sulfopropionic anhydride. The method has the advantages of cheap and easily available raw materials, simple operation and high yield, and is suitable for large-scale production.

The application belongs to the field of auxiliary agents, and particularly relates to a filler dispersant matched with alcohol-soluble ink and a preparation method thereof. The preparation method is as follows: polyether and phosphide are mixed to obtain a premix; the premix is heated, and then an acidifying agent is added to react to obtain a reaction product; the reaction product is sequentially cooled, filtered, discharged and packaged. The polyether, the phosphide and the acidifying agent are used to prepare the dispersant under strict operation conditions, the high-level dispersion and viscosity reduction ability of the alcohol-soluble ink when simultaneously using organic and inorganic fillers are improved, the dispersant is used for solvent type, solvent-free coating and printing ink, can stabilize the organic and inorganic fillers, especially titanium dioxide and silicon dioxide, can significantly reduce the viscosity of the grinding material, and increase the wetting and stability, and great convenience is provided and the cost is reduced.

Disclosed are an amyloid β measurement method and a reagent capable of more accurately measuring amyloid β and unaffected by molecular target drugs (antibody drugs) for amyloid β. Provided is an immunoassay method for amyloid β in a sample isolated from a living body including a pretreatment step for mixing a sample isolated from a living body, (1) an acidifying agent, and (2) at least one selected from the group consisting of cationic surfactants, zwitterionic surfactants, protein denaturants, and chelating agents.

The invention provides fructus podophylli jelly with the efficacy of improving qi deficiency and blood stasis and a preparation method of the fructus podophylli jelly. The fructus podophylli jelly is formed by mixing liquid medicine prepared from a traditional Chinese medicine composition and konjac powder according to a preset proportion, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1 to 5 parts of fructus podophylli, 0.5 to 2.5 parts of semen ziziphi spinosae, 0.5 to 2.5 parts of radix astragali seu hedysari, 0.5 to 2.5 parts of arillus longan, 16 to 20 parts of gel, 2 to 10 parts of sweetening agent and 0.9 to 1.4 parts of acidulant. The preparation method of the fructus podophylli jelly with the efficacy of improving qi deficiency and blood stasis comprises the following steps: putting medicinal materials into a pot, adding a proper amount of clear water, soaking the medicinal materials for a first preset time, boiling, and continuously stewing with second preset fire for a second preset time; filtering the mixed liquid, and adding konjac powder, a sweetening agent and an acidulant which are prepared in advance into the liquid medicine; continuously stewing for a third preset time, and transferring the formed gel into the mold to obtain the finished product fructus podophylli jelly which is an innovative jelly product with the efficacy of improving qi deficiency and blood stasis and good taste.

This invention discloses a method for preparing a low-irritant feed acidifier, belonging to the field of feed additives. The preparation method includes preparing fumaric acid-treated sodium lignin sulfonate, preparing glutathione-treated sodium lignin sulfonate, and mixing them to prepare the acidifier. The acidifier emulsion prepared by this invention exhibits good stability. When the stability of the acidifier emulsion is tested according to the method in GB / T1603-2001, the emulsion does not exhibit stratification or precipitation.

This invention provides a method for preparing sulfated polysaccharides suitable for the production of microcapsules. [Solution] The present invention relates to a method for preparing sulfated polysaccharides. A mixture comprising at least one polysaccharide and at least one polar aprotic solvent is prepared in this method. At least one sulfating agent, at least one acetylating agent, and at least one peroxydisulfate are added to the mixture, and the mixture is then subjected to a temperature treatment so that at least one polysaccharide is converted to at least one sulfated acetate polysaccharide. At least one sulfated acetate polysaccharide is separated from the mixture and converted to a sulfated polysaccharide. The present invention further relates to sulfated polysaccharides that can be prepared using the method according to the present invention. The present invention further relates to microcapsules and methods for producing microcapsules.

The invention belongs to the technical field of preparation of dairy products, and particularly relates to camel milk gel, camel milk yoghourt and a preparation method thereof. The camel milk gel comprises an acidifying agent and camel milk casein, and the particle size of the gel is less than or equal to 3.6 microns. According to the camel milk gel disclosed by the invention, the particle size of gel in a casein solution in camel milk is reduced to 3.6 microns or below, so that the gel with the water-holding capacity reaching 50% or above, namely the camel milk gel disclosed by the invention, can be obtained.

A composition for treating dentin hypersensitivity, comprising: a first component comprising: (i) a first rheology modifying polymer; (ii) a calcium ion source; (iii) a positively charged basic amino acid; and (iv) an acidifying agent, wherein the first component has a pH in the range of about 2.0 to about 7.0; a second component comprising: (i) a second rheology modifying polymer; (ii) a phosphate ion source; and (iii) an alkalizing agent, wherein the second component has a pH in the range of about 7.0 to about 14.0; wherein the first component and the second component are combined into a mixture such that a cationic amorphous calcium phosphate gel composition is created instantly when the pH of the mixture reaches a pH range of about 7.0 to about 9.5.

The application discloses a kind of active humic acid slow-release fertilizer for saline-alkali soil improvement and a preparation method thereof, and belongs to the technical field of slow-release fertilizer preparation.The active humic acid slow-release fertilizer for saline-alkali soil improvement is composed of the following components in parts by weight: 30-40 parts of humic acid, 10-15 parts of urea, 10-20 parts of superphosphoric acid calcium, 10-15 parts of ammonium sulfate, 18-26 parts of composite film agent and 2-5 parts of modified acidifying agent.The slow-release fertilizer prepared using the above-mentioned substances has excellent slow-release performance and high utilization rate.

Composition, in particular pharmaceutical composition, in the form of a fixed dosage (solid dosage form) for sucking and / or chewing, preferably for sucking, in particular lozenge, preferably for use in the prophylactic and / or therapeutic topical (local) treatment of inflammatory diseases of the mouth and throat, wherein the composition contains an effective, in particular pharmaceutically and / or therapeutically effective, amount of an active ingredient preferably suitable and / or effective for the topical (local) treatment of inflammatory diseases of the mouth and throat, in particular with antiseptic and / or antimicrobial properties, preferably with antibacterial and / or antiviral and / or antifungal properties, wherein the active ingredient is incorporated and / or embedded in a solid matrix, wherein the composition, in particular the solid dosage form and / or the matrix, releases the active ingredient upon topical (local) application and / or use, preferably by sucking and / or chewing, preferably by sucking, in the oral and pharyngeal cavity; wherein the active ingredient is octenidine, in particular in the form of a pharmaceutically compatible and / or physiologically acceptable salt or ester, preferably in the form of a pharmaceutically compatible and / or physiologically acceptable salt, particularly preferably octenidine dihydrochloride; and wherein the composition, in particular the solid dosage form and / or the matrix, furthermore and / or additionally contains at least one further ingredient (a) and / or (b), in particular (a) and (b), wherein the at least one further ingredient (a) and / or (b) is selected from the group of (a) Flavor modulators, in particular selected from the group of the following components (i), (ii) and / or (iii): (i) Bitter (taste) masking agents, in particular selected from the group consisting of bitter taste receptor antagonists, preferably 4-(2,2,3-trimethylcyclopentyl)butanoic acid, and saponins, preferably glycyrrhizic acid (glycyrrhizin) and its salts or esters and / or glycyrrhetinic acid (glycyrrhetin) and its salts or esters, complexing agents, in particular cyclodextrins, and combinations or mixtures thereof, (ii) Bitter substances, in particular coffee extract and / or tea extract and / or their respective bitter substances, preferably coffee extract and / or its bitter substances, (iii) preferably natural or nature-identical (aroma) oils and / or essential oils, in particular with antiseptic and / or antimicrobial properties, preferably with antibacterial, antifungal and / or antiviral properties, in particular selected from the group of anise oils, in particular star anise oil, peppermint oil, eucalyptus oil, lavender oil, tea tree oil, chamomile oil, clove oil, rosemary oil, caraway oil, cinnamon oil, sage oil and fennel oil, as well as combinations or mixtures thereof; in particular wherein the ingredient (a) and / or the flavor modulator comprises a combination of at least two different components (i), (ii) and / or (iii), preferably a combination of components (i), (ii) and (iii); (b) Acidulants, in particular saliva-stimulating and / or flavor-enhancing acidulants, preferably acidulants authorized under pharmaceutical and / or food law and / or acidulants authorized as pharmaceutical additives and / or food additives, in particular selected from the group of tartaric acid and its salts, in particular sodium tartrate, sodium potassium tartrate (Rochelle salt) and calcium tartrate, citric acid and its salts, metatartaric acid, fumaric acid, ascorbic acid, phosphoric acid and its salts, stannous chloride, in particular tin(II) chloride, malic acid, lactic acid, adipic acid, succinic acid and other pharmaceutically compatible and / or physiologically acceptable organic acids and their salts, as well as their combinations or mixtures.

The application relates to the field of silica preparation, and particularly discloses a preparation method of precipitated silica with low hydroxyl content, wherein solid sodium silicate with a modulus of 3.0-3.5 is selected, a water glass solution with a concentration of 15-20 wt% is prepared, and sulfuric acid with a concentration of 18-25 wt% is prepared as an acidifying agent; SO2, calcium hydroxide is added into the prepared sodium silicate solution, impurity removal and purification treatment are carried out, and after standing and filtering, the purified sodium silicate solution which can be used for reaction is obtained. Through precise control of the reaction conditions, the parameters such as acid-base flow rate, reaction temperature and pH in different reaction stages are controlled, the surface hydroxyl content of the target product is significantly reduced, and before preparation, the impurity-removed water glass solution is obtained by taking calcium hydroxide as a sodium silicate purifying agent, so that the purity of the reaction product is higher, and when the reaction product is used for rubber mixing, the reaction product is not prone to agglomeration and thickening.

The disclosure relates to compositions, including ready-to-use spray or wipe compositions, that are non-toxic, non-corrosive, biodegradable acidic antimicrobial compositions that exhibit broad-spectrum antimicrobial efficacy, wherein the compositions comprise an amine oxide, such as an alkyl amine oxide, in combination with an acidulant. Beneficially, the acidic antimicrobial compositions are capable of achieving at least a 3-log microbial reduction within 5 minutes under relatively mild pH conditions. The compositions provide cleaning and sanitizing.

The invention relates to a curable compound which can be removed using moisture, the compound comprising the following components: (A) a tertiary epoxide; (B) a vinyl ether; and (C) a latent acidifier for the cationic polymerisation. Component (A) and / or component (B) comprise at least one at least difunctional compound. Component (B) is present in a proportion of at least 25 wt.%, based on the total weight of the compound; and components (B) and (A) are present in the compound in a ratio of at least 1.5:1, based on the proportion by weight of the particular component relative to the total weight of the compound. The invention also relates to the use of such a compound and to a method for gluing, coating or casting.

The invention relates to a precipitated silica, characterized in that it has the following physico-chemical parameters: The precipitated silica according to the invention is produced by the following method: a) initial charge of an aqueous solution of organic and / or inorganic salts and / or alkali and / or alkaline earth silicates and / or organic and / or inorganic bases with pH > 9, b) simultaneous metering of water glass and acidifying agent to this initial charge while stirring at 80 to 98°C for 60 to 120 minutes, c) then stopping the addition of water glass and metering the acid only in smaller amounts than before in order to bring the pH of the mixture (measured at 60°C) to 9.0 to 10.0, d) then stirring the mixture at high temperature > 85°C for 45 minutes to 200 minutes without further addition of reactants, e) acidification using sulfuric acid to a pH of about 3.5 to 4.5 (measured at 60°C) and f) filtration, drying to < 8% loss on drying and then granulation of the mixture. The silica according to the invention can be used for the production of rubber mixtures, in particular for the production of tyres, cable sheaths, hoses, drive belts, conveyor belts, roller coverings, shoe soles, gasket elements and damping elements.

The invention relates to an acidifying agent for reducing ammonia emission through storage and fermentation of pig manure water and application of the acidifying agent. The acidifying agent is prepared from ardealite, ferrous sulfate and thermally activated natural starch according to the mass ratio of 3: 3: 4. The acidifying agent comprises the following elements in percentage by weight: 37.2% of C, 5.8% of H, 46.7% of O, 3.5% of Fe, 2.6% of P and 4.2% of S. According to the invention, the industrial waste phosphogypsum is subjected to resource utilization, so that resource waste is reduced; meanwhile, the acidifying agent takes inorganic acid as a crystal nucleus and a macromolecular organic carbon chain as a framework, a macromolecular organic-inorganic composite acidification system is built, after addition, the pH of a fermentation system can be rapidly reduced, the activity of microorganisms in the system is regulated and controlled, the synergistic effect of the acidifying agent and microbial acidification is achieved, the acidification efficiency is improved, and the acidifying effect is improved. The low pH can be effectively kept for a long time, and rapid and continuous storage, fermentation and acidification of the pig manure water are achieved.

The present technology relates to a method of treating crude methanol comprising the steps in temporal order of distilling the crude methanol to remove at least a portion of one or more sulphurous compounds from the crude methanol and provide a methanol-rich stream, contacting the methanol-rich stream with an oxidant, whereby at least a part of the sulphur compounds in the stream is oxidized, and contacting the methanol-rich stream with an acidifying agent, whereby ammonia present in the stream reacts to form ammonium sulphate in a methanol- rich stream, essentially free of polymerised terpenes.

The invention discloses a compound feed additive containing cationic antibacterial peptide and application of the compound feed additive, and belongs to the technical field of animal nutrition and feed additives. The compound feed additive consists of the following components in percentage by mass: 10-30% of cationic antibacterial peptide, 5-15% of a saccharomyces cerevisiae viable bacteria preparation, 20-40% of butyric acid and 25-50% of milk powder. Through the synergistic effect of the antibacterial peptide, the probiotics, the acidifying agent and the food calling component, weaning stress can be effectively relieved, the feed intake and daily gain of piglets are remarkably increased, the feed conversion ratio and diarrhea rate are reduced, and intestinal health is improved. The additive is safe, free of residues and convenient to use, and is an ideal choice for replacing an antibiotic growth promoter, so that the additive has better application prospect and value in the technical field of animal nutrition and feed additives.

The invention discloses a preparation method for increasing the hydroxyl value of liquid rubber, which comprises the following steps: replacing a polymerization kettle with inert atmosphere gas, maintaining micro-positive pressure, sequentially adding a solvent, a regulator, a monomer and an initiator into the polymerization kettle, carrying out first reaction, adding an acidifying agent, adding an oxidizing agent, and carrying out second reaction, and after the reaction is finished, washing, vacuumizing to remove the solvent, and drying to obtain the polyhydroxy liquid rubber. According to the preparation method, the hydroxyl value of the liquid rubber can be increased, and the problem that the hydroxyl value content of the hydroxyl-terminated liquid rubber prepared by an anion solution method is low is solved.

The present invention relates to a method for producing shaped rice parts, comprising the following steps: (a) cooking rice; (b) producing a starch-based adhesive mixture containing water, an acidifying agent, a plant starch, optionally a preservative and optionally a thickening agent; (c) mixing the cooked rice with the adhesive mixture to obtain a homogeneous dough; (d) shaping shaped parts from the dough obtained in step (c) and optionally coating it with breadcrumbs; (e) heating the shaped part obtained in step (d) until a core temperature of at least 80°C has been reached; (f) cooling the shaped part to room temperature and subsequently packaging it. The present invention further relates to a method for producing precooked, long-life rice, to starch-based adhesive granules, to a shaped rice part itself and to microwave products.

The utility model relates to acidification agent preparation technical field especially relates to a kind of positive optimal acid slow-release granule acidification agent preparation equipment, including preparation bucket and top cover, rotationally connected with the shaft in the preparation bucket, screening component is installed in the preparation bucket, the screening component includes leakproof ring, screen, extruding block, limit stop, arc block, fixed plate, straight spring, the leakproof ring is fixedly connected on the inner wall of the preparation bucket, the leakproof ring is hollowly provided, the screen is slidably connected in the leakproof ring, the utility model cooperates with the part such as limit stop, leakproof ring, straight spring to make screen reciprocating left and right movement and slow-release granule are screened, avoid the foreign matter in slow-release granule to participate in preparation work, improve the purity of product, reciprocating screen also can increase screening rate, while also can screen out the raw material of larger granule, avoid subsequent uneven stirring phenomenon.

The invention discloses probiotic salad dressing with an intestinal regulation function and a preparation method of the probiotic salad dressing, and belongs to the technical field of food processing. The salad dressing comprises the following components in parts by weight: 40-60 parts of a grease base material, 5-15 parts of an acidulant, 3-10 parts of probiotic microcapsules, 3-10 parts of seasonings and 10-30 parts of water. The preparation method adopts a core sterile post-addition process, namely, firstly, the salad dressing base is subjected to high-temperature instantaneous sterilization and cooling, and then the probiotics and the sterile base are mixed and filled in a sterile environment. Through combination of a microcapsule embedding technology and a sterile post-addition technology, the problem that probiotics are prone to inactivation in the salad dressing acid environment, the production process and the storage period is effectively solved, it is ensured that the product keeps a high viable count in the whole shelf life, the product can tolerate the human digestive tract environment, and the exact intestinal tract regulation function is achieved.

The present application provides a method for extracting phenolic substances from coal tar, which comprises: primary extraction: extracting poor phenol oil by using a composite organic amine aqueous solution to obtain a dephenolized oil A and a rich phenol extraction phase A; secondary extraction: extracting a rich phenol fraction oil by using the rich phenol extraction phase A to obtain a dephenolized oil B and a rich phenol extraction phase B, wherein the poor phenol oil is obtained by mixing coal tar and the dephenolized oil B, and the rich phenol fraction oil is a fraction oil of the coal tar; acidification: acidifying the rich phenol extraction phase B by using an acidifying agent to obtain a crude phenol oil C and a composite organic amine aqueous solution rich in the acidifying agent through separation; and extractant regeneration: removing the acidifying agent from the composite organic amine aqueous solution rich in the acidifying agent to obtain the composite organic amine aqueous solution for recycling in the primary extraction step. The method of the present application is resource-saving, green and pollution-free, has low process energy consumption, and the crude phenol oil product has high purity.

The invention provides large intestine targeted release type probiotic soft sweets and a preparation method thereof. The soft sweets comprise functional microspheres and matrix slurry, the functional microsphere comprises a probiotic core layer, a chemotactic signal layer and a targeting layer from inside to outside, the matrix slurry comprises a gelling agent, a sweetening agent, an acidulant, fruit essence and water. The probiotic core layer comprises probiotics and extracellular polysaccharide secreted by the probiotics; the chemotactic signal layer comprises a specific chemotactic agent; the targeting layer comprises an antibacterial peptide which is generated by inducing the probiotics. The functional microspheres provided by the invention can realize targeted release of probiotics in the soft sweets in large intestines, and the matrix slurry enables the soft sweets to have good chewing feeling and to be quickly disintegrated in the stomach to release the microspheres without influencing the functions of the microspheres, and can effectively protect the structures and thallus activity of the microspheres; and the retention rate of viable bacteria in the shelf life is also kept at a relatively high level.