338 results about "Supersaturation" patented technology

The invention discloses silver powder with a high twin crystal ratio and a preparation method and application of the silver powder with the high twin crystal ratio. The preparation method comprises the following steps that S1, a carboxylic acid coordination agent is added into a silver source solution, and a silver precursor solution is obtained; sequentially adding a dispersing agent and an initiator into the reducing agent solution to obtain a reaction base solution; s2, a silver precursor solution is added into the reaction base solution for an oxidation-reduction reaction, then curing is conducted, and mixed mother liquor is obtained; s3, the mixed mother liquor is filtered, washed, dispersed and dried, and then the silver powder with the high twin crystal proportion is obtained; the initiator comprises one or more of sulfate, carbonate and nitrate; through the synergistic effect of the initiator and the carboxylic acid coordination agent, the silver ion release rate and the crystal nucleus preferential growth direction are regulated and controlled, the rapid feeding and curing technology is combined, the low supersaturation environment is constructed, the silver powder is induced to grow in the specific direction, and the twin crystal proportion is remarkably increased.

The invention provides a cooling rate optimization control method and system for continuous cooling crystallization, and the method comprises the steps: collecting crystal slurry concentration data and temperature data of each stage of crystallization tank in real time; the crystal slurry concentration data, the temperature data and the feeding flow data are input into a deep learning model, and a prediction result is obtained; based on the prediction result and crystal mush concentration data, dynamically adjusting the cooling rate of each stage of crystallizing tank and the addition amount of a co-crystallizing solvent; and feeding back an outlet crystal mush concentration signal of the last-stage crystallizing tank to the solid-liquid separation unit, and adjusting the running rotating speed of the solid-liquid separation unit in a linkage manner. According to the cooling rate optimization control method and system for continuous cooling crystallization, prospective correction of the cooling rate is carried out by using the predicted supersaturation degree, and adjustment of the additive amount of the auxiliary crystallization solvent is carried out by using the predicted crystal particle size distribution; and finally, an outlet concentration signal of the last-stage crystallizing tank is fed back to the solid-liquid separation unit in real time to adjust the separation rotating speed in a linkage manner, so that the crystal particle size deviation is reduced, and the triazole crystallization recovery rate is improved.

The invention discloses an atmospheric trace water-soluble metal element automatic sampling and pretreatment system, the system comprises an automatic sampling module and a pretreatment module, the automatic sampling module is provided with a gas introduction device, a gas corrosion device and a mixing growth chamber from front to back in sequence, and the mixing growth chamber is connected with the pretreatment module; the gas corrosion device is used for separating particulate matters and gas in a to-be-collected atmospheric sample, and the mixed growth chamber enables the particulate matters to grow and condense in supersaturated water vapor to obtain a primary sample; the pretreatment module comprises a sample enrichment unit and an automatic calibration unit; the sample enrichment unit is used for carrying out enrichment treatment on the primary sample through a bubble remover and a plastic injector; the automatic calibration unit is used for sequentially carrying out acid pickling, water washing, sample dilution and quantitative calibration on the enriched sample to finish the pretreatment process of the sample; according to the system, the sampling efficiency and the data reliability are remarkably improved, the automation degree is high, manual operation is reduced, personal errors are reduced, and the monitoring efficiency is improved.

The invention discloses a wave-absorbing material chemical coprecipitation reaction kettle, and relates to the technical field of chemical engineering equipment and functional material preparation, the reaction kettle comprises the following components: a three-stage gradient reaction cavity structure, an anti-pollution structure and a multi-physics field coupling control platform; through the design of a three-stage gradient reaction cavity structure, optimal distribution of a fluid field is realized, stable and efficient flowing of a reaction solution among different cavities is ensured, a multi-axis intelligent mixing system in a premixing area can quickly mix a precursor solution to achieve a molecular-level mixing state, an ideal initial condition is provided for subsequent reaction, and the reaction efficiency is improved. The nucleation area realizes uniform nucleation of nanocrystal nuclei through accurate temperature control and chemical environment control, the grain size distribution range is effectively reduced, the growth area controls preferred growth of crystal faces through adjustment of magnetic field intensity and solution supersaturation degree, particles with good monodispersity are obtained, and under the combined action of the designs, the particle size distribution range is effectively reduced. The reaction efficiency and the consistency of the product quality are obviously improved.

The invention belongs to the field of wastewater treatment and crystallization kinetics, and provides a kinetics prediction method for induced crystallization of calcium sulfate in wastewater, which comprises the following steps: detecting to obtain a water quality index, and calculating the solution supersaturation degree S and the initial chemical potential driving force delta mu through the water quality index; calculating values of a first saturation parameter a, a second saturation parameter b and a third saturation parameter c according to the saturation S; according to the parameters a, b and c and the chemical potential driving force delta mu, calcium ion concentration values at different crystallization moments are calculated, and the progress of removing Ca < 2 + > in the wastewater is determined. According to the method, the ion concentration change value under each crystallization reaction condition can be calculated, the accurate regulation and control of the calcium sulfate crystallization process are realized, and a theoretical support is provided for the industrial process control of calcium sulfate induced crystallization.

The invention relates to the technical field of medicine preparation, and discloses preparation and application of monomer zinc lysine and a reconverted zinc lysine complex, and a preparation method of the monomer zinc lysine, which comprises the following steps: by taking L-lysine hydrochloride as a raw material, adding zinc chloride and sodium hydroxide to react, adjusting the pH value to be neutral, concentrating, adding ethanol to obtain a supersaturated solution, heating to 60 DEG C, standing, and filtering to obtain the monomer zinc lysine. The weight ratio of the L-lysine hydrochloride to the sodium hydroxide to the zinc chloride is 2: 2: 1, the pH value is adjusted to 6.5-7.5, the addition amount of the ethanol is 1.5-2 times of the total volume of the materials, and the concentration of the ethanol is 72-74 degrees. According to the method, the process is mature, complicated production equipment is not required, and the only used organic reagent is ethanol, so that the problem that acetic acid, citric acid and sodium phosphate buffers are frequently used in the existing preparation process of the monomer zinc lysine and then converting the monomer zinc lysine into the zinc lysine complex, so that impurities such as phosphoric acid and the like are generated is solved.

The invention belongs to the field of separation and purification of bio-based chemicals, and particularly relates to a method for separating and purifying levoglucosenone from bio-oil. According to the method, the bio-oil obtained in the process of preparing levoglucosenone (LGO) through selective pyrolysis of biomass is used as a raw material, organic acid in the bio-oil is removed through a supersaturated carbonate solution, and then an oil phase is obtained through step-by-step extraction. And then adjusting working conditions, carrying out echelon reduced pressure distillation on the oil phase, and sequentially removing the extracting agent, low-boiling-point impurities and high-boiling-point oligomers, so as to obtain high-purity LGO. The pyrolysis bio-oil is subjected to coupling treatment of deacidification, step-by-step extraction and echelon reduced pressure distillation, so that the aim of separating and purifying high-added-value chemicals from low-value and complex-component bio-oil is fulfilled. The raw materials are cheap and easy to obtain, the process is simple, and the method is a biomass resource utilization method with great prospects.

The invention discloses a method, a system, a medium and equipment for predicting hydrogen in oxygen of an alkaline electrolysis system, and the method comprises the steps: obtaining a total calculation formula for predicting hydrogen in oxygen of the alkaline electrolysis system based on the contribution of dissolved hydrogen which is not separated by a gas-liquid separator, gaseous hydrogen which is not separated by the gas-liquid separator, electrolytic bath saturation diffusion and electrolytic bath supersaturation diffusion mechanisms to hydrogen in oxygen of the system; according to experimental data of the alkaline electrolysis system under different alkaline liquid circulation flow working conditions, calibrating a to-be-fitted coefficient; according to experimental data of the alkaline electrolysis system under different system pressure working conditions, calibrating a to-be-fitted coefficient; according to experimental data of the alkaline electrolysis system under different working current working conditions, calibrating a to-be-fitted coefficient; according to experimental data of the alkaline electrolysis system under different temperature working conditions, a to-be-fitted coefficient sum is calibrated; and inputting temperature, pressure, alkali liquor circulation flow and current experiment data of the alkaline electrolysis system, and calculating hydrogen in oxygen of the alkaline electrolysis system so as to output system HTO under different operation conditions in real time.

The invention discloses a process for optimizing the crystal habit of an acesulfame potassium product. The process comprises the following steps: heating and dissolving an acesulfame crude product and a solvent to prepare a supersaturated solution, firstly, sequentially carrying out activated carbon adsorption and membrane adsorption for decoloration, then cooling at a certain rate for cooling crystallization, adding a certain amount of primary seed crystal in a nucleation stage 1, adding a certain amount of secondary seed crystal in a nucleation stage 2, and after the temperature of the material is reduced to 10 DEG C, cooling and crystallizing to obtain the acesulfame potassium crystal. And centrifugally drying the material to obtain the acesulfame potassium stable crystal form product. According to the present invention, the suitable solvent and the suitable cooling rate are selected, and the seed crystal is added during the cooling crystallization process, such that the content of the metastable crystal form is significantly reduced, the content of the stable crystal form is increased, and the particle size distribution, the yield and the purity of the acesulfame potassium product are effectively improved so as to solve the caking problem of the acesulfame potassium product during the storage process.

The invention relates to the field of lithium ion batteries, in particular to a method for continuous microwave-assisted hydrothermal synthesis of LiFe < 1-x > Mn < x > PO4 nanocrystals. The method comprises the following steps: (1) synthesizing Li3PO4 turbid liquid by using a micro-channel reactor; and (2) taking the Li3PO4 suspension as a precursor, adding FeSO4. 7H2O and MnSO4.H2O into the suspension, introducing the suspension into a tubular delay reactor, and carrying out microwave-assisted heating to realize rapid and continuous synthesis of the LiFe1-xMnxPO4 solid solution with small size and uniform particle size distribution. The microchannel reactor is used for synthesizing Li3PO4 particles, micromixing can provide a uniform supersaturated environment for nucleation of the Li3PO4 particles, so that the particles with small size and uniform particle size distribution are more favorably generated, and finally, the tubular delay reactor and microwave-assisted heating are combined to quickly and continuously synthesize the LiFe1-xMnxPO4 solid solution with uniform and fine grain size. Meanwhile, continuous feeding can be achieved, so that continuous synthesis of LiFe < 1-x > MnxPO4 is achieved, and the problem that continuous synthesis is difficult to achieve through traditional hydrothermal synthesis can be solved.

The invention belongs to the technical field of tungsten hydrometallurgy, and particularly relates to a method for improving the crystallization rate of ammonium paratungstate, which comprises the following steps: S1, obtaining an ammonium tungstate solution which comprises metatungstate ions; s2, adding a supersaturation degree regulator into the ammonium tungstate solution, wherein the supersaturation degree regulator comprises hydrogen peroxide and ammonia water; s3, heating the ammonium tungstate solution to a first temperature, and then adding superfine ammonium paratungstate; s4, the ammonium tungstate solution is heated to a second temperature, heat preservation and continuous stirring are conducted, and ammonium paratungstate crystals are obtained; by adjusting parameters such as temperature, pH value, solvent type and concentration, optimizing crystallization conditions with metatungstate ions and ammonium paratungstate at the same time, improving the crystallization rate, and by controlling the degree of supersaturation of the solution, the situation that the crystallization rate is affected due to non-uniform crystal growth caused by too high crystallization rate is avoided, and the quality of the product is improved. The supersaturation degree can be controlled by adjusting parameters such as solution concentration and temperature.

The invention relates to the field of potassium chloride purification, and provides an analytically pure potassium chloride purification method, which comprises: S1, dissolving industrial grade potassium chloride, adding a refining agent to remove impurities, and filtering to obtain a supersaturated potassium chloride solution; s2, performing variable-speed cooling crystallization treatment on the supersaturated potassium chloride solution to obtain a potassium chloride crystal mixture; s3, performing crystal layer pretreatment on the potassium chloride crystal mixture to obtain a potassium chloride crystal layer; s4, carrying out gradient spraying washing treatment on the potassium chloride crystal layer to obtain a potassium chloride crystal wet material; s5, drying the potassium chloride crystal wet material to obtain analytically pure potassium chloride; the method is simple in process equipment and mild in operation condition, and analytically pure potassium chloride can be stably prepared under the condition of conventional equipment.

The invention is suitable for the field of nuclear power detection, and discloses a method and device for measuring the content of dissolved iron in liquid lead bismuth, and the method comprises the following steps: S1, taking out the liquid lead bismuth, adding the liquid lead bismuth into a test container, and heating the liquid lead bismuth to a set temperature by a heating assembly; s2, argon is injected into the test container to exclude other gases, then oxygen is input, and the change of the concentration of dissolved oxygen in the liquid lead bismuth is measured through an oxygen detection sensor; s3, substituting the measured oxygen concentration change rate and the net oxygen adding rate into a differential equation, and calculating to obtain a solubility product; and S4, deducing the content of the dissolved iron according to the measured equilibrium oxygen concentration in the saturated iron and the solubility product obtained in the step S3. The method for measuring the oxygen activity of the dissolved lead-bismuth eutectic through the oxygen detection sensor is easy and convenient to operate, the content of dissolved iron can be rapidly and accurately measured, the liquid metal system is always in a balanced state by adjusting the oxygen adding rate in the system, and the experiment efficiency is higher.

The invention belongs to the technical field of automatic control, and discloses a cyclopropylamine (R)-mandelate crystallization process feedback control method, which comprises the following steps: acquiring the concentration, solvent temperature, stirring speed and pH value of cyclopropylamine (R)-mandelate in a solvent in real time, and forming a state parameter set reflecting the real-time state of a cyclopropylamine (R)-mandelate crystallization system; based on the state parameter set, deriving a solute supersaturation degree change rate, a nucleation rate and a crystal growth rate by adopting an explicit kinetic relationship to obtain a kinetic feature set of the cyclopropylamine (R)-mandelate; collecting the grain size, the shape and the crystallization uniformity of the crystal, and constructing a corresponding crystal quality prediction function in combination with the kinetic feature set of the cyclopropylamine (R)-mandelate to obtain a predicted crystal quality index; comparing the actually detected crystal morphology index with the predicted crystal quality index, and calculating to obtain a deviation value; the crystal quality of the cyclopropylamine (R)-mandelate is improved.

The invention relates to the technical field of single crystal preparation, in particular to a preparation method of a desonide single crystal. The method comprises the following steps: adding a desonide sample into a solvent 1; ultrasonically dissolving to a saturated state; adding a solvent 2 into the mixture, uniformly shaking, and filtering; adding the obtained clear filtrate into a bottle, adding a solvent 3 again, and sealing with a sealing film; pricking a hole in a sealing film of the sealed bottle; standing and culturing at the temperature of 20-30 DEG C, separating out crystals, removing supernate, enabling a crystallization system to slowly reach supersaturation by controlling different solvents and solution temperature, and promoting ordered growth of the crystals to obtain the single crystal of desonide. And irradiating the single crystal by using an X-Ray diffractometer under specific conditions to obtain a diffraction pattern and diffraction data.

The invention discloses a preparation method of a vanadium dichloride material, and belongs to the field of chemical engineering. The method comprises the following steps: a, putting crude metal vanadium powder into an atmosphere furnace, introducing argon for emptying, introducing hydrogen chloride gas, and heating for chlorination reaction; b, after the reaction is completed, cooling to a certain temperature, introducing argon, continuously cooling to room temperature, then taking out a reaction product, and grinding in an argon atmosphere; c, putting the reaction product into the atmosphere furnace, and repeating the operation of the steps a and b to obtain a secondary chlorination product; d, putting the secondary chlorination product into an organic solvent, carrying out ultrasonic dispersion, filtering and separating to obtain a vanadium dichloride-organic solvent solution; and e, distilling the solution under the protection of argon to obtain a supersaturated solution, filtering, and drying in vacuum to obtain the vanadium dichloride material. The method disclosed by the invention is simple in process, convenient in condition control and relatively low in production cost, and a vanadium dichloride product with relatively high purity can be obtained.

The invention discloses a micro-flow field preparation method of dasatinib nanocrystals. The method comprises the following steps: dissolving dasatinib in an organic solvent to serve as a solvent phase A; dissolving a surfactant in deionized water to serve as an anti-solvent phase B, simultaneously pumping the solvent phase A and the anti-solvent phase B into a micro-flow field device for full reaction, collecting dasatinib crystal dispersion liquid at an outlet, centrifuging to remove supernate, taking bottom precipitate, and performing vacuum drying to obtain the solid nanocrystal. According to the present invention, the micro-flow field device is adopted, the mixing process of the solvent and the anti-solvent is enhanced, the surfactant is adopted as the dispersant, the transport efficiency and the supersaturation degree of the drug molecules are regulated and controlled, the efficient preparation of the dasatinib nanocrystal is achieved, the operation is simple, the reaction speed is fast, and the safety is high.

This invention discloses a pretreatment method for detecting trace perfluorinated and polyfluoroalkyl substances (PFAS) in complex matrix textiles, belonging to the field of materials analysis technology. The method involves placing the textile in an alkaline solvent containing an alkyl sulfonate displacing agent. Under heating conditions, the displacing agent utilizes its competitive adsorption mechanism to forcibly occupy matrix adsorption sites and displace the target analytes into the solvent. Subsequently, the temperature is rapidly lowered to the phase separation induction temperature, inducing supersaturation precipitation of the displacing agent, which then encapsulates impurities in situ and co-precipitates, forming a solid-liquid stratified system. Finally, the supernatant is collected for analysis. This invention utilizes the dual properties of the displacing agent—high-temperature solubilization and low-temperature phase change removal—to effectively break the strong adsorption equilibrium of aged textiles without using a solid-phase extraction column. This solves the contradiction between low extraction rate and significant matrix interference, significantly improving the recovery rate of PFAS. It offers advantages such as low cost, simple operation, and high accuracy.

Improvement are proposed to increase the size accuracy and resolving power with which variants of the variable saturation condensation particle sizer (VSCPS) of Gallar et al. (2006) may characterize particles suspended in a gas. One essential component of this invention is an efficient method to achieve saturation of the gas flow passing through a saturation chamber, independently from the value of the gas flow rate through that chamber. The resulting strict linearity between the maximum vapor saturation ratio achieved in the instrument and the finely controlled gas flow rate through the saturator facilitates the precise inference of particle size, as well as the possibility to determine size without lengthy calibrations. Also described is a novel approach to introduce the particles to be sized in the center of a stream of vapor laden sheath gas. The new sheathing method delays the flow instability in prior sheathing schemes, where the aerosol was injected from a centered capillary into the surrounding sheath gas / vapor mixture. In one embodiment of this invention, the centered aerosol flow is fed at the bottom of a cylindrical tube, while the gas / vapor mixture enters laterally through the porous walls of this tube. This mixing approach is intrinsically stable over a much wider range of flow rates of sheath and aerosol, allowing for improvements in sizing resolution. In another embodiment the flow in the mixing region is stabilized by accelerating the gas either in the missing region or after it. A method to infer a condensation size without the need of extensive calibration or complex numerical computations is also disclosed.

The utility model provides a wet-process phosphoric acid extraction tank sulfuric acid adding device which comprises a sulfuric acid main pipeline, a plurality of branch assemblies are arranged on the sulfuric acid main pipeline and used for extending into an extraction tank, and the discharging ends of the branch assemblies are all located below the liquid level in the extraction tank. The branch assembly comprises a branch main pipeline, a first valve, a flow meter and a second valve, and the first valve, the flow meter and the second valve are sequentially installed on the branch main pipeline in series. A plurality of branch pipes are arranged on the side, close to the discharging end, of the branch main pipeline, and each branch pipe is provided with a third valve. According to the utility model, the degree of supersaturation of slurry in the extraction tank can be effectively improved in actual use, and gypsum crystallization is improved; meanwhile, overflow of fluorine can be reduced, and gas-phase fluorine is fixed into a liquid phase to be recycled.

A process for producing a polymorphic or pseudo-polymorphic crystalline phase from a plurality of compounds (C,D,S1,S2), comprising the steps of preparing (I) a supersaturated solution from said compounds, homogenizing (II) said supersaturated solution in an ultrasonic bath, transferring (III) the supersaturated solution into a plurality of heated tubes (54), aging (V) the solutions transferred into the tubes for a determined period, exposing said tubes (54) to a pulsed and polarized laser beam before and / or during exposure, monitoring in situ the nucleation and then the growth of co-crystals inside said tubes (54), and filtering the exposed solutions to recover co-crystals larger than a predetermined minimum size.This process is implemented to carry out co-crystallization from at least one active substance (D) and one co-former (C) in at least one first solvent (S1) and one second solvent (S2), and it further comprises two preliminary steps: establishing a phase diagram from the respective physicochemical characteristics of said active substance (D), said co-former (C), said first solvent (S1) and said second solvent (S2), and then determining, from said phase diagram thus established, concentration, temperature and exposure conditions providing a stable phase for the production of co-crystals. See Figure 4.

The application belongs to the technical field of inorganic fine chemical phosphate purification, and provides a high-purity trisodium phosphate and a preparation method thereof. The preparation method comprises the following steps: (1) preparing a trisodium phosphate saturated crude slurry; (2) adjusting the quality of the slurry: after the trisodium phosphate saturated crude slurry is warmed, it is placed and kept warm; (3) purification: the temperature of the adjusted slurry is controlled and kept; then, anhydrous trisodium phosphate homologous slow-release seeds are added into the slurry; the system supersaturation is adjusted in two stages; the stirring is stopped to perform normal-pressure static crystal growth, and the purified slurry is obtained; and (4) post-treatment. The prepared high-purity trisodium phosphate has extremely low impurity contents of heavy metals and anion by-products, and has regular crystal morphology and strong crystal form stability, and is not prone to problems such as caking and hydrolysis during storage.

To provide a user-friendly cloud chamber for observing a radiation ray.SOLUTION: In a cloud chamber 100, a steam supply device 250 supplies steam 204 to an observation room 202, the supplied steam 204 in the observation room 202 is cooled to form a supersaturation steam layer 206, and a track of a radiation ray passing through the supersaturation steam layer 206 is observed. In the cloud chamber 100, a cooling box 310 that includes a cooling plate 312 having a plurality of cooling plates 330 for cooling the steam 204 in the observation room 202 is provided, a mixture of generated dry ice 304 generated from liquefied carbon dioxide 384 and gaseous carbon dioxide is introduced into the cooling box 310, the generated dry ice 304 is accumulated in a passage formed by the plurality of cooling plates 330, and the accumulated generated dry ice 304 cools the steam 204 in the observation room 202 via the cooling plate 312.SELECTED DRAWING: Figure 1

The invention belongs to the crossing field of fine chemical engineering, crystal engineering and continuous production technologies, and particularly relates to a process and a device for continuously preparing 1, 3-cyclohexanedione crystals. The method comprises the following steps: respectively introducing a pre-cooled 1, 3-cyclohexanedione monosodium salt aqueous solution and an acidifying agent into a static mixer through a metering pump for mixing, introducing the materials into an aging tank for aging, and carrying out solid-liquid separation on the aged materials to obtain 1, 3-cyclohexanedione crystals. The invention provides a process and a device for continuously preparing a 1, 3-cyclohexanedione crystal, the process and the device are a brand-new continuous acidification crystallization process and system based on a static mixer, and aims to fundamentally eliminate local supersaturation, realize accurate control of the crystal form and morphology of 1, 3-cyclohexanedione and produce a high-quality flaky crystal form product. And the continuity, the stabilization and the high efficiency of the production process are realized.

Techniques are described for preparing a dispersion of nanobubbles in an aqueous fluid (e.g., water or brine) at high pressure to produce a dispersion having a large amount of one or more gases that are typically immiscible with the aqueous fluid. The composition of the aqueous fluid may be adjusted to contain an optimized amount of gas under desired pressure conditions. The gas may be present in the dispersion as an amount dissolved in the aqueous fluid and as dispersed nanobubbles. The thermodynamic model may be used to determine the amount of gas that may be present in the dispersion of nanobubbles and / or to determine or optimize the composition of the fluid.

A decomposition reactor equipped with a thermochemical decomposition reactor for performing a thermochemical decomposition of a hydrocarbon feedstock such as methane or natural gas, as well as a method for performing the thermochemical decomposition and process for obtaining a carbon product therefrom. The thermochemical decomposition reactor holds a supersaturated molten mixture primarily of a metal and carbon, where the metal is Mn, Fe, Co and Ni or an alloy comprising more than 50% of the metal. A heater heats and maintains supersaturated molten mixture in supersaturation with carbon while the hydrocarbon feedstock is injected to pass through the supersaturated molten mixture and be pyrolyzed to yield pyrolysis products that primarily include hydrogen and the desired carbon product. A hydrogen extraction means extracts the hydrogen and carbon product and a carbon separation means separates the carbon product preferably including a solid carbon product that is highly graphitic.

The invention relates to a calcium chloride injection and a production method thereof, and relates to the technical field of calcium chloride injection production, a solvent of the calcium chloride is water for injection, and the injection contains the following components: 80-120 g / L of calcium chloride; the concentration of the water for injection is 800-1200 g / L; hydrochloric acid is a proper amount of component for adjusting the pH value to 5.3-5.8; and the sodium hydroxide is a proper amount of component used for adjusting the pH value to 5.3-5.8. According to the calcium chloride injection and the production method thereof, the problems of solution turbidity, calcium ion precipitation, oxidative degradation and the like caused by insufficient dissolution and local supersaturation of calcium chloride in the prior art are effectively solved by accurately controlling the concentration of calcium chloride and adopting a nitrogen protection dissolution process. Meanwhile, a 0.22 mu m polyethersulfone two-stage filter element series connection filtering process, an integrity testing process with the foaming point larger than or equal to 3450 kPa and a sterilization and leak detection integrated process are adopted, the sterility guarantee level and stability of the product are remarkably improved, the endotoxin of the finished product is smaller than 0.5 EU / mL, the number of visible foreign matter larger than or equal to 10 mu m is reduced by larger than or equal to 60%, and the clinical safety and effectiveness of the injection are ensured.

The invention discloses a method for purifying metal impurities in cobaltous sulfate, a pure cobaltous sulfate product and application of the pure cobaltous sulfate product, and the purification method comprises the following steps: 1) evaporating a cobaltous sulfate aqueous solution to a supersaturated state, cooling and crystallizing, and heating; and 2) carrying out solid-liquid separation to obtain crystals and mother liquor. By adopting the purification method disclosed by the invention, the content of each metal impurity in the cobaltous sulfate is reduced to be below 100ppb, and the use requirements of the electroplating liquid for cobalt interconnection of the integrated circuit are met.

The invention relates to a method for producing a polymorphic or pseudo-polymorphic crystalline phase from a plurality of compounds (C, D, S1, S2), the method comprising steps of preparing (I) a supersaturated solution from the compounds, homogenizing (II) the supersaturated solution in an ultrasonic bath, transferring (III) the supersaturated solution into a plurality of heated tubes (54), aging (V) the solutions transferred into the tubes for a predetermined period of time, exposing the tubes (54) to a polarized pulsed laser beam before and / or during exposure, followed in situ by nucleation and then growing cocrystals inside the tubes (54), and filtering the exposed solutions in order to recover cocrystals having a size greater than a predetermined minimum size. This method is carried out in order to obtain cocrystallization from at least one active substance (D) and a coformer (C) in at least a first solvent (S1) and a second solvent (S2).

The invention discloses a hydrotreating catalyst as well as a preparation method and application thereof. The method comprises the following steps: impregnating an alumina-based carrier in an impregnation liquid containing dopamine, a protective agent and hydrogenation active metal in a supersaturated manner, adjusting the pH value of the system to enable the dopamine to be self-polymerized on the surface of a pore channel of the alumina-based carrier, and then washing, drying, pre-depositing carbon and roasting to obtain the hydrotreating catalyst. The hydrogenation catalyst prepared by the method provided by the invention has obviously improved desulfurization and denitrification activity and stability.