The present invention discloses a marble goby compound feed containing fermented silkworm chrysalis and a use thereof. The compound feed does not contain fish meal, and comprises fermented silkworm chrysalis, alpha-starch, wheat flour, wheat gluten flour, zeolite powder, calcium biphosphate, salt and premix for carnivorous fish. The fermented silkworm chrysalis is prepared by adding mixed meal into the silkworm chrysalis, inoculating microbe, adding carbon sources and inorganic salts, fermenting and culturing the mixture. The microbe is a mixed bacterio-liquid containing bacillus subtilis, bacillus acidi lactic and yeast. According to the present invention, the marble goby compound feed does not contain any fish meal and fish meat products, is produced from fermented silkworm chrysalis, can completely replace pure live fish and ice fish for breeding, increases survival rate and growth rate of marble goby, improves quality of fish meat, significantly increases the economic benefits of aquaculture, and promotes the sustained, healthy and stable development of marble goby aquaculture.