The present invention relates to bacterial probiotics useful in
aquaculture. Specifically, it discloses a selection of non-hemolytic, proteolytic, stress-tolerant bacterial strains with enhanced quorum-
quenching capabilities. Moreover, the method allows detection of novel species of
bacteria whose
probiotic attributes could be massive for
aquaculture. From the isolated
bacteria, selected species were tested for their
probiotic efficacy in
Nile tilapia (
Oreochromis niloticus), a key
fish species in global finfish
aquaculture. The species demonstrated significant
efficacy in improving the health and growth performance of
Nile tilapia juveniles.
Specific growth rates and
weight gain, and improved feed conversion ratios without adverse effects on
fish health were observed. The
gut microbiome was positively influenced by promoting
beneficial bacteria while reducing harmful (opportunistic) species, leading to improved
immune modulation. Survival rates were significantly boosted during a pathogenic challenge, and key immune genes were upregulated, indicating stronger local immune defenses. These findings show that the selected
probiotic species offer substantial benefits for growth, feed efficiency, and
disease resistance, emphasizing their potential for widespread application as probiotics in aquaculture.