118 results about "Mannan" patented technology

The invention provides a fertilizer synergist for reducing nutrient loss and inhibiting nitrification and application of the fertilizer synergist. The fertilizer synergist is prepared from the following components in percentage by mass: 95 to 98 percent of carboxyl cross-linked modified montmorillonite, 0.05 to 0.1 percent of mannan oligosaccharide, 0.1 to 0.5 percent of mannan, 1 to 3 percent of polyaspartate and 0.5 to 2 percent of a nitrification inhibiting aid. According to the fertilizer synergist capable of reducing nutrient loss and inhibiting nitrification and the application of the fertilizer synergist, the fertilizer synergist serves as a plant nutrient loss control synergist and a nitrification inhibitor and can activate a crop stress resistance signal source, promote and induce synthesis of endogenous auxin in plants, root and growth, activate phosphorus and dissolve potassium, reduce nitrogen loss and improve the yield of the plants. The fertilizer utilization rate is improved.

The invention discloses an oral monoclonal antibody micro-coated nanopolysaccharide microsphere preparation for targeted therapy of inflammatory bowel diseases and a preparation method thereof. According to the method, oxidized mannan and an anti-TNF-alpha monoclonal antibody are mixed and cross-linked by a cross-linking agent containing a diselenide bond to form the drug-loaded nanoparticles. Mixing the drug-loaded nanoparticles with pectin, dropwise adding the mixture into a calcium chloride solution through an electrostatic spinning device, and carrying out ionic crosslinking to obtain the oral monoclonal antibody micro-coated nano polysaccharide microsphere preparation with the particle size range of 180-200 microns. The drug-loaded polysaccharide microsphere delivers the wrapped drug-loaded nanoparticles to a colitis disease part through electrostatic interaction. The drug-loaded nanoparticles are targeted to macrophages, release of the monoclonal antibody is accelerated under the triggering of high-concentration active oxygen at an inflammation part, and the oral stability and the treatment effect of the monoclonal antibody drug are improved. The polysaccharide is used as a monoclonal antibody targeted delivery carrier, raw materials are cheap and easy to obtain, the preparation process is simple and convenient, reaction conditions are mild, and application and development are easy.

The invention discloses a preparation method of a mycotoxin degrading enzyme intelligent slow-release feed additive, and relates to the technical field of feed additive production, a double-emulsion embedding technology is adopted, enzyme is embedded in a multi-layer shell composed of chitosan, sodium alginate and an enteric polymer Eudragit S100, and then Ca < 2 + > ion cross-linking solidification is performed to obtain the mycotoxin degrading enzyme intelligent slow-release feed additive. And finally, freeze-drying or spray-drying to obtain the core-shell structure microcapsule. The obtained microcapsules are compounded with functional carriers such as yeast cell walls, sodium aluminosilicate, mannan oligosaccharide, talcum powder and the like to prepare finished products which can be directly added into various feeds. The release rate of the additive in simulated gastric juice with the pH value of 2.0 for 4 hours is lower than 15%, the release rate of the additive in simulated intestinal juice with the pH value of 6.8 for 6 hours exceeds 90%, the enzyme activity can be effectively protected, and targeted release of intestinal tracts is achieved; meanwhile, the compound carrier has a synergistic adsorption effect on various mycotoxins, and the degradation rates of aflatoxin B1, zearalenone and ochratoxin A in an in-vitro experiment respectively reach 87% or above.

The invention relates to bacillus subtilis Y32, and the preservation number of the bacillus subtilis Y32 is CGMCC (China General Microbiological Culture Collection Center) No.34819. The strain can produce xylanase with high temperature resistance and high stability, various hydrolases such as beta-mannase, protease and the like, exopolysaccharides and botrytis cinerea inhibition, and is resistant to acid, swine bile salt and 10% NaCl. The optimum temperature of xylanase produced by the strain is 55 DEG C, the optimum pH value is 6.0, under the conditions, the half-life period is 12.5 h, the relative enzyme activity is still kept above 80% after incubation for 3 h, and the xylanase has good thermal stability. The strain can also improve the yield of cucumbers and pinellia ternate, and can also improve the laying rate of 70-week-old hyline brown laying hens from 70.4% to 90.1%. The strain has a good application prospect in the fields of agriculture, food processing and cosmetic production.

The invention provides a compound feed for promoting beef cattle growth and improving meat quality and a production method thereof, and belongs to the technical field of feed preparation. The compound feed comprises the following components in parts by weight: 100 parts of basal feed, 7-10 parts of a functional additive and 0.3-0.5 part of disodium inosinate, and the functional additive comprises a postbiotic compound, a fatty acid regulating agent, a bacterium enzyme synergist and trace elements, wherein the metagen complex comprises a lactobacillus plantarum metagen extract and a bacillus coagulans metagen extract, the fatty acid regulating agent comprises conjugated linoleic acid glyceride and medium-chain fatty acid, and the bacterial enzyme synergist comprises beta-mannase and bacillus subtilis. According to the compound feed, the growth performance and the meat quality can be synchronously improved, and a reliable processing technical guarantee is provided for improving the growth performance and the meat quality of beef cattle.

The invention belongs to the technical field of biological medicines, and relates to application of mannatide in preparation of a medicine for treating alcoholic gastric ulcer. The mannatide disclosed by the invention can be used for remarkably relieving gastric tissue hemorrhagic lesion and ulcer conditions of alcoholic gastric ulcer for the first time, and the mechanism comprises the following steps: reducing active oxygen generated by alcohol toxicity, and improving oxidative stress of a body by improving antioxidant enzyme activity of the gastric tissue; the inflammatory response of the organism is regulated by regulating and controlling an Akt / NF-kB pathway; a Bax-related apoptosis pathway is inhibited to protect gastric mucosa cells from alcohol-induced apoptosis, so that the integrity of gastric tissue mucosa is protected; the intestinal flora disorder caused by alcohol intake is regulated and controlled, and the acute alcoholic gastric ulcer is prevented by improving the intestinal flora composition of the alcoholic gastric ulcer. The application range of the mannatide is widened, and more solutions are provided for prevention or treatment of acute alcoholic gastric ulcer.

Disclosed is a cancer vaccine that contains dendritic cells. The dendritic cells are prepared by: culturing immature dendritic cells to maturation; co-culturing the matured dendritic cells with attenuated cancer cells, Mannan – BAM (Mannan, a yeast-derived polysaccharide, and BAM, a Biocompatible Anchor for Cell Membrane), and TLR (Toll like receptor) agonists; and optionally sorting the dendritic cells from the co-cultured attenuated cancer cells.

The invention discloses a composite particle with a prebiotic function and colon-targeted co-delivery performance as well as a preparation method and application thereof, and belongs to the technical field of functional foods and intestinal micro-ecological regulators. According to the composite particle, the curcumin and the resveratrol are encapsulated by the peanut protein isolate to form a nano core, the outer layer of the nano core is a composite shell layer composed of the carboxymethyl konjac glucomannan and the prebiotics, a stable core-shell structure is formed, and the composite particle is small in particle size, good in dispersity and stability and good in stability. The stability of a protein-based delivery system in a gastrointestinal tract environment can be obviously improved; the release rate of the composite particles in simulated gastric juice and intestinal juice is low, and the composite particles can be specifically degraded and release active ingredients in simulated colon fluid containing beta-mannase, so that colon-targeted co-delivery can be realized. The composite particle disclosed by the invention is simple in preparation process and stable in function, can be applied to the fields of functional foods, health foods, formula foods for special medical purposes and the like, realizes dual purposes of active component delivery and intestinal microenvironment regulation, and has a wide application prospect.

The invention relates to the technical field of probiotic preparations, in particular to a composite prebiotic embedded lactobacillus rhamnosus microcapsule as well as a preparation method and application thereof. The preparation method of the composite prebiotics embedded lactobacillus rhamnosus microcapsule comprises the following steps: (1) stirring and mixing isomaltooligosacharide and galactomannan in water, then adding sodium alginate, and stirring and mixing to obtain a mixed solution; (2) mixing the mixed solution with a bacterium suspension of lactobacillus rhamnosus to obtain a compound bacterium solution; and (3) injecting the compound bacteria liquid into the curing liquid to obtain gel beads, and then standing to obtain the gel beads. According to the microcapsule provided by the invention, three encapsulating materials are adopted to achieve a synergistic effect, so that the encapsulating efficiency of the microcapsule can be effectively improved, and meanwhile, the structural stability of the microcapsule is improved. Experiments prove that the microcapsule can effectively improve the survival rate of the probiotics in gastrointestinal tracts, more accurately control release of the probiotics and provide technical support for development of probiotic functional products.

The invention relates to the field of functional additives for daily chemicals, and particularly discloses hydrolyzed procyanidine freeze-dried powder and a preparation method thereof. The hydrolyzed procyanidine freeze-dried powder is prepared by freeze-drying and comprises the following raw materials in parts by weight: 0.1-0.2 part of hydrolyzed procyanidine, 25-35 parts of carnosine, 10-20 parts of a stabilizer, 0.1-0.3 part of acetyl hexapeptide-8 and 45-55 parts of water. The stabilizer is selected from at least one of mannan, trehalose, mannitol, cane sugar, betaine, whey protein, PVP (Polyvinyl Pyrrolidone), PEG (Polyethylene Glycol), glycine, histidine, leucine, sodium alginate, beta-cyclodextrin, maltodextrin and chitosan. The hydrolyzed procyanidine freeze-dried powder has good storage stability, can keep activity for a long time, is still stable after being dissolved in water for a long time, and has less activity loss.

The utility model discloses disc type separating equipment, which relates to the technical field of mannatide preparation equipment and comprises a disc type separating machine main body, the disc separator main body is arranged on the buffer mounting seat; wherein the buffer mounting seat comprises a mounting top plate, a mounting bottom plate and a plurality of damping shock absorbers, the mounting bottom plate is arranged on the mounting structure, the mounting top plate is arranged above the mounting bottom plate, and the damping shock absorbers are arranged between the mounting top plate and the mounting bottom plate and detachably connected with the mounting top plate and the mounting bottom plate; the disc separator main body is arranged on the mounting top plate and is detachably connected with the mounting top plate, so that the problem that the axis of a transmission rotating shaft in the conventional disc separator is easy to deviate, crack and even break after being used for a long time is solved.

The invention discloses a method for preparing ganoderan rich in a mannogalactan structure from a Chryseobacterium bacterium GS-7 and Ganoderma lucidum YJ0724 and application of the ganoderan rich in the mannogalactan structure, and relates to the technical field of microbial fermention.The method comprises the following steps that a Chryseobacterium bacterium GS-7 seed solution is prepared, and a Ganoderma lucidum YJ0724 seed solution is prepared; the method comprises the following steps: a, simultaneously inoculating a seed solution of a Chryseobacterium bacterium GS-7 and a seed solution of Ganoderma lucidum YJ0724 into a fermentation medium for co-culture to obtain a fermentation solution containing Ganoderma lucidum polysaccharide rich in a mannan galactan structure; or b, filtering and degerming the fermentation liquor of the Chryseobacterium bacterium GS-7, and inoculating the fermentation liquor and the ganoderma lucidum YJ0724 seed solution into the culture medium for co-culture to obtain the fermentation liquor containing the ganoderma lucidum polysaccharide rich in the mannogalactan structure. The obtained ganoderma lucidum polysaccharide rich in the mannogalactan structure can improve the immunomodulatory activity.

The application discloses a process for improving the quality of palm kernel meal feed by enzyme and bacteria synergistic fermentation, and belongs to the field of feed biotechnology.The process is characterized by the following steps: crushing and screening palm kernel meal, mixing the palm kernel meal with 20% bran and 4% ammonium sulfate as dry matter to obtain a basic substrate;compounding bacillus subtilis, aspergillus niger and saccharomyces cerevisiae at a ratio of 1:1:1 of viable bacterial number, adding 0.67% mannanase and 0.3% xylanase to prepare a bacteria-enzyme mixed solution, inoculating the bacteria-enzyme mixed solution at a 10% inoculation amount, adjusting the moisture content to 50% and the pH to 6.4, and then sealing and storing the bacteria-enzyme mixed solution for use after 4 days of fermentation at 33.5 DEG C; and the bacteria-enzyme mixed solution can be stored for a long time.The process can efficiently degrade crude fiber and anti-nutritional factors, improve the protein content and the digestibility, is stable and easy to mass-produce, can replace part of corn and soybean meal in the daily ration of ruminants, and realizes high-value utilization of palm kernel meal.

The invention relates to the technical field of food processing, and discloses a low-sulfur semi-sweet wine anti-oxidation method which comprises the following steps: S1, selecting wine grapes, removing stems, crushing and squeezing to obtain grape juice; s2, performing alcoholic fermentation on the grape juice, and stopping fermentation when the residual sugar content is 12-45g / L to obtain base wine; s3, an antioxidant combination is added into the base liquor, the antioxidant combination comprises 5-10 mg / L of glutathione, 5-10 mg / L of mannan and 15-20 mg / L of sulfite, and the materials are mixed to be uniform; and S4, filtering the base wine added with the antioxidant, bottling, and storing to obtain the low-sulfur semi-sweet wine. Through the synergistic effect of glutathione, mannan and sulfite, the antioxidant insufficiency under the low SO2 concentration is made up, and the dual effects of low vulcanization and stable quality are achieved.

The application belongs to the technical field of microcapsules, and particularly relates to a preparation method of a composite probiotic capsule, which comprises the following steps: uniformly mixing probiotic bacterial liquid, fructooligosaccharide, tea polyphenol, grape polyphenol, mannan oligosaccharide, isomaltitol and an emulsifier to obtain a core material; uniformly mixing glycerol and distilled water, heating to 60-80 DEG C, sequentially adding modified gelatin, hydroxypropyl starch and chitosan, stirring for 10-30 min, sterilizing, and cooling to room temperature to obtain a capsule material; mixing the core material and the capsule material, performing high-pressure homogenization treatment, and then performing spray drying to obtain the composite probiotic capsule; and the modified gelatin is prepared by acylation reaction of succinic acid derivatives and gelatin. The composite probiotic capsule provided by the application has excellent storage stability, antioxidant property, anti-gastric juice erosion capacity, and also has good enteric solubility and bioavailability.

This invention belongs to the field of biological breeding technology, specifically involving SlCSLA2 Application of genes in improving the storage and transportability of tomato fruit. This invention addresses the industry problem of severe storage and transport losses in tomatoes due to excessive softening after harvest. For the first time, it utilizes CRISPR / Cas9 gene editing technology to knock out the cell wall hemicellulose (mannan) synthase gene. SlCSLA2 This invention has led to the creation of a tomato mutant with significantly enhanced fruit firmness. The firmness of the entire fruit during the red-ripe stage is 35%–42% higher than that of the wild type, and the firmness can be maintained for about a week after harvest, effectively delaying the softening process and significantly improving storage and transportability. This invention provides new gene targets and technical approaches for breeding tomato varieties with improved storage and transportability.

The invention belongs to the field of gene engineering and enzyme engineering, and particularly relates to mannase derived from space mutagenesis yeast strains as well as a preparation method, a product and application of the mannase. The amino acid sequence of the mannase is as shown in SEQ ID NO.2, and the nucleotide sequence of the mannase is as shown in SEQ ID NO.3. The mutant retains 70% of enzyme activity at a high temperature (85 DEG C for 3 min, and only 40% of original enzyme remains at 85 DEG C for 3 min) and has an acid pH value (the stability is improved from 3% to 25% after treatment for 180 min at pH 3.0), and meanwhile, the mutant has the low-temperature efficient catalytic characteristics that the optimum pH value is 7.0, the optimum temperature is 40 DEG C, and 30% of enzyme activity is kept at 20 DEG C, and has remarkable application potential in the fields of feed, paper-making industry and the like.

The invention provides a feed additive for increasing the content of n-3 polyunsaturated fatty acids in pork and a compound feed. The feed additive consists of spartina alterniflora powder and a bacterial enzyme additive, the bacterial enzyme additive is prepared from lactobacillus plantarum, aspergillus niger, yarrowia lipolytica, bacillus subtilis, cellulase, beta-mannase and protease; the compound feed comprises a basic ration and the feed additive. Through development and utilization of spartina alterniflora powder and practice, waste is turned into wealth, a new source of the feed additive is expanded, and the feed additive is added into daily ration, so that the digestibility of neutral detergent fibers of the daily ration is improved, the antioxidant capacity of serum is enhanced, and the contents of alpha-linolenic acid, arachidonic acid and eicosapentaenoic acid in pork are increased.

The present invention belongs to the technical field of antibacterial agents and discloses a preparation method and application of a specific molecular weight mannan polysaccharide composite inhibitor. Specifically, a specific molecular weight mannan polysaccharide with a weight-average molecular weight of 6.1 kDa to 7.7 kDa is first prepared by yeast. This specific molecular weight mannan polysaccharide is then added to a fermentation medium inoculated with Lactobacillus plantarum for fermentation to obtain a fermentation broth. The supernatant of the fermentation broth is collected as the specific molecular weight mannan polysaccharide composite inhibitor. This preparation method is environmentally friendly and low-cost. The specific molecular weight mannan polysaccharide composite inhibitor is added to the culture medium to effectively inhibit the growth of Escherichia coli and Staphylococcus aureus. The present invention is suitable for use as a feed additive.

The preparation method comprises the following steps: (1) compounding hermetia illucens larvae, whole tenebrio molitor and euphausia superba according to a mass ratio of (3-5): (2-4): 1, carrying out enzymolysis, and reacting with a yeast cell wall extract to form a glycopeptide compound; (2) coating the glycopeptide compound with a mannan oligosaccharide and chitosan solution to form microcapsules, and controlling the release rate of the microcapsules in simulated gastric juice to be lower than 30% and the release rate of the microcapsules in simulated intestinal juice to be higher than 80%; (3) co-fermenting the microcapsules, clostridium butyricum and pediococcus acidilactici, and adsorbing fermentation liquor on the porous starch; (4) performing dry mixing on the functional compound, the fermentation compound and the base material, and performing low-temperature puffing; and (5) sequentially spraying a vitamin D3 grease layer, a pectin-whey protein protective layer and a solution containing TGF-beta2 on the surfaces of the particles. Through cooperation of multiple processes, the immune function and intestinal health of pets are remarkably improved, and the product is good in stability and palatability.

The present disclosure provides synthetic compositions useful as inhibitors of mannan-binding lectin-associated serine protease-2 (MASP-2), including compositions that selectively inhibit MASP-2 over thrombin, as well as methods for their production and use.

The utility model relates to the technical field of mannose oligomer, and provides a positioning device for mannose oligomer filling, which comprises a conveyor, a controller and an L-shaped plate fixedly mounted on the rear side of the conveyor, and two electric push rods are oppositely and fixedly mounted on the inner top wall of the L-shaped plate. During use, the conveyor is started to convey a filling bottle, when the infrared sensor detects the filling bottle, information is transmitted to the controller, the controller controls the conveyor to be closed, the electric push rod is started, the electric push rod pushes the discharging pipe on the strip-shaped plate to move downwards, the discharging pipe extends into the filling bottle, and the filling bottle is discharged. Meanwhile, mannan-oligosaccharide is pumped out through a pump body in the feeding mechanism, the amount of the conveyed mannan-oligosaccharide is detected through a solid flow meter, when the amount reaches a set range, information is transmitted to a controller, the pump body in the feeding mechanism is closed through the controller, and the mannan-oligosaccharide is conveyed out through the solid flow meter; therefore, the purposes of automatic filling and quantitative filling of the mannose oligomer are achieved.

The invention belongs to the field of biological fermentation feeds, and discloses a preparation method and application of a Sophora alopecuroides feed based on multi-bacterial enzyme synergistic fermentation, and particularly relates to a preparation method of a Sophora alopecuroides feed based on multi-bacterial enzyme synergistic fermentation by taking Sophora alopecuroides straw as a raw material, adopting a complex microbial inoculant composed of lactobacillus plantarum, saccharomyces cerevisiae, bacillus subtilis and aspergillus niger, cooperating with cellulase and beta-mannase, and performing multi-bacterial enzyme synergistic fermentation. The compound is prepared through a two-stage fermentation process of aerobic enzyme production and anaerobic detoxification. The invention provides a preparation method and application of a Sophora alopecuroides feed based on multi-bacterial enzyme synergistic fermentation, toxic alkaloids in Sophora alopecuroides can be efficiently degraded, the crude protein content can be significantly increased, and fibers can be degraded, and after the prepared fermented feed replaces corn in daily ration of mutton sheep, the daily gain of the mutton sheep can be significantly increased, the feed-to-weight ratio can be reduced, and the production cost can be reduced. The flavor and the nutritional value of the mutton are improved, high-valued and safe utilization of toxic agricultural wastes is realized, and a new scheme is provided for green breeding and high-quality animal product production.

The invention relates to the technical field of daily chemical products and cosmetics, in particular to a scalp repair composition containing epidermis repair polysaccharide and saccharomycetes lysate. The skin repairing composition is prepared from the following raw materials in percentage by mass: 1 to 5 percent of skin repairing polysaccharide; 1%-5% of a yeast lysate; 1%-10% of PEG-5 (Polyethylene Glycol) glycerate triisostearate; and the balance of cosmetically acceptable matrix. The polysaccharide is mannan which is obtained by fermenting Paenibacillus sp.1538, and the weight-average molecular weight of the mannan is 6.15 * 10 < 6 > Da. The specific ultra-high molecular weight polysaccharide is compounded with the saccharomyces cerevisiae extract, and the low-irritation PEG-5 glycerate triisostearate is introduced, so that the compatibility problem that the high molecular weight polysaccharide is easy to flocculate is effectively solved. The composition can form a film immediately, deeply resist inflammation, relieve and repair a physical barrier of scalp, has an excellent synergistic effect, and solves the problem of scalp chemical stimulation injury caused by a traditional surfactant from the source.

The invention relates to the technical field of feed production, and particularly provides a compound enzyme and application thereof in enzymolysis of palm meal. The compound enzyme is specially designed according to the nutritional characteristics of the palm meal, non-starch polysaccharide components such as protein, cellulose and mannan in the palm meal can be effectively subjected to enzymolysis, the anti-nutrition effect of non-starch polysaccharide is reduced, the content of soluble oligosaccharide, small molecular protein and the like is increased, and the feeding value of the palm meal is improved.

The invention discloses a preparation method for improving the stability of soybean protein isolate-konjac mannan emulsion, and belongs to the technical field of application of vegetable protein structures. The method comprises the following steps: (1) fully dissolving a soybean protein isolate solution with a certain concentration, and fully hydrating; (2) adding a certain amount of konjac mannan, and reacting at high temperature; and (3) adding six different sodium salt ions into the soybean protein isolate-konjac mannan compound. And (4) respectively mixing the samples in the steps (1), (2) and (3) with sunflower seed oil, and shearing at a high speed to obtain the emulsion. Six sodium salt ions are introduced, the emulsion particle size of the soybean protein isolate-konjac mannan compound is reduced through the Hough-Merster effect, the stability of the emulsion is improved, and under the freezing condition, the emulsion also shows higher freeze injury resistance and emulsion cracking resistance. The method has a certain reference value for the food industry.

A method for obtaining highly sulfated nanoparticles of cellulose or sulfated nanoparticles of mannan, or a combination thereof, from endosperms, comprising acquiring a ground flour of an endosperm of a seed, nut, or pit, wherein the ground flour contains polysaccharides, and wherein the polysaccharides contain either cellulose or mannan, or both cellulose and mannan; pretreating the ground flour to condition the polysaccharides for hydrolysis and functionalization thereof; preparing a reagent for hydrolysis and functionalization of the polysaccharides, wherein the reagent comprises a solution of glycerol, water, and sulfuric acid at predetermined concentrations; adding the reagent to the pretreated polysaccharides to form a suspension, wherein adding the reagent to the suspension converts the cellulose or mannan or both into nanoparticles that are sulfated by the reagent; separating the sulfated nanoparticles from the suspension; washing the nanoparticles; and creating a stable colloidal suspension of the sulfated nanoparticles. The sulfated nanoparticles are used in pharmaceutical, cosmetic, wound healing, and skin treatment formulations.

The invention belongs to the field of biomass energy utilization, and particularly relates to a method for preparing high-value dehydrated sugar through rapid pyrolysis based on extremely dilute acid high-temperature modification. The method comprises the following steps: by taking palm plant seed waste as a raw material, carrying out boiling-washing modification at a temperature close to a boiling point by using an acid aqueous solution with extremely dilute concentration, preferably further carrying out cold plasma discharge modification treatment, and then carrying out rapid pyrolysis under an anaerobic condition at 350-450 DEG C, and condensing the obtained pyrolysis steam to obtain a liquid product rich in levomannan (LM, 1, 6-anhydro-beta-D-mannopyranose). According to the method, ash can be effectively removed, the reaction activity of the raw materials is improved, high-purity enrichment of LM is promoted, and a technical approach is provided for high-value utilization of palm plant seed waste.

The invention relates to the technical field of animal husbandry, and discloses application of hemicellulose and mannan in regulation of growth performance of sheep. The content of hemicellulose is 10.3% DM or 17% DM, and the addition amount of mannan is 80-160 mg / kg DM. According to the application of the hemicellulose and the mannan in regulating the growth performance of the sheep, the mannan is added into daily ration, so that the digestibility of animals to dry matters, crude proteins, neutral detergent fibers and acid detergent fibers can be increased, and the content of total acid, acetic acid, propionic acid, butyric acid and other volatile fatty acids in rumen can be increased; according to the present invention, with the feed, the richness and the diversity of the flora are increased, the richness of the firmicophyta, the spirochete and the like is improved, the intestinal flora of the sheep is adjusted, the blood sugar is reduced, and the daily ration with different hemicellulose levels has different influences on the growth performance, the rumen microorganisms, the metabolite and the lipid metabolism of the sheep; and a theoretical basis is provided for research and development of the yeast-source functional feed additive.