31 results about "Galactan" patented technology

The invention discloses a composition containing D-chiro-inositol as well as a preparation method and application of the composition. The composition comprises D-chiro-inositol, Myo-inositol and microcapsule powder, wherein the wall material of the microcapsule powder consists of anhydride modified edible protein and a polysaccharide compound; the edible protein is selected from at least one of spirulina protein, quinoa protein, whey protein and soybean protein; the polysaccharide compound comprises at least one of fucoidin and larch arabinogalactan. Active components are also embedded in the microcapsule powder, and comprise at least one of Omega-3, coenzyme Q10, astaxanthin and vitamin. According to the composition, the stability and bioavailability of fat-soluble active ingredients are improved through microencapsulation, and the composition has a synergistic effect with components such as D-chiro-inositol and Myoinositol, so that insulin resistance is effectively improved, female hormone balance is adjusted, and polycystic ovarian syndrome is improved. The process is simple, is suitable for large-scale production, and can be widely applied to dietary supplements or functional foods.

The invention discloses a high-nutrition additive-free candy jam based on seaweed dietary fibers and a preparation method of the high-nutrition additive-free candy jam. The jam comprises the following components in parts by weight: 55-70 parts of a fruit base material, 0.7-1.3 parts of sugar beet-sourced low-methoxy amidated pectin, 2.2-4.2 parts of a seaweed dietary fiber compound system, 0.06-0.18 part of calcium salt, 0.08-0.25 part of an anthocyanin stable system and the balance of water, and exogenous saccharides and artificial or natural sugar substitutes are not added. Wherein the methoxylation degree of pectin is smaller than or equal to 35%, the amidation degree of pectin is 5-20%, and the seaweed dietary fiber compound system comprises brown seaweed soluble dietary fibers and red seaweed galactan dietary fibers. The preparation method comprises the following steps: pulping at low temperature and adjusting acid, dispersing and hydrating polysaccharide, adding glue in batches, degassing and controlling oxygen in stages, introducing laccase for covalent cross-linking, adding calcium in stages to form ionic cross-linking, adding an anthocyanin stabilizing system, filling at low temperature, and carrying out 580-620MPa ultrahigh pressure treatment. A stable gel structure and good water binding capacity are obtained under the condition of no exogenous sugar, bleeding is reduced, anthocyanin and color stability are improved, and meanwhile non-thermal sterilization and storage period safety are achieved.

The antioxidant activity of alpha-tocopherol polyethylene glycol 1000 succinate (TPGS) and of alpha-tocopherol succinate (TS) has been examined in isolated hepatocytes and microsomal fractions from rat liver. Both TPGS and TS require esterase activity to yield free alpha-tocopherol and, hence, antioxidant activity. TPGS and TS consistently exerted a more effective antioxidant protection than an equivalent amount of directly-added free alpha-tocopherol. The low antioxidant efficiency of directly added free alpha-tocopherol in such water-based experimental systems as used here seems to be due to its extreme hydrophobicity. TPGS, on the other hand, is an extremely hydrophilic compound which is being examined as a useful source of alpha-tocopherol in certain clinical situations and is here shown to be a convenient and effective source for experimental studies into lipid peroxidation and antioxidant mechanisms.

The invention provides a novel application of L-beta-galactoglucan, and particularly provides an application of the L-beta-galactoglucan in the aspect of resisting vaginitis.

The invention discloses a method for preparing ganoderan rich in a mannogalactan structure from a Chryseobacterium bacterium GS-7 and Ganoderma lucidum YJ0724 and application of the ganoderan rich in the mannogalactan structure, and relates to the technical field of microbial fermention.The method comprises the following steps that a Chryseobacterium bacterium GS-7 seed solution is prepared, and a Ganoderma lucidum YJ0724 seed solution is prepared; the method comprises the following steps: a, simultaneously inoculating a seed solution of a Chryseobacterium bacterium GS-7 and a seed solution of Ganoderma lucidum YJ0724 into a fermentation medium for co-culture to obtain a fermentation solution containing Ganoderma lucidum polysaccharide rich in a mannan galactan structure; or b, filtering and degerming the fermentation liquor of the Chryseobacterium bacterium GS-7, and inoculating the fermentation liquor and the ganoderma lucidum YJ0724 seed solution into the culture medium for co-culture to obtain the fermentation liquor containing the ganoderma lucidum polysaccharide rich in the mannogalactan structure. The obtained ganoderma lucidum polysaccharide rich in the mannogalactan structure can improve the immunomodulatory activity.

The invention provides yellow-rose yellow-meat boletus fucomannan as well as a composition, a preparation method and application thereof, and belongs to the technical field of biological medicine mass health. The fucomannan has a structure represented by a general formula in an attached drawing of the abstract, and n represents the number of sugar repeating units and is a natural number. The weight-average molecular weight of the fucose glucomannan galactan of the boletus fucose is 10 kDa to 20 kDa, the polydispersity coefficient of the fucose glucomannan galactan is 1 to 2, and the molar ratio of glucose to mannose to fucose to galactose is 1.00 to 3.08 to 2.84 to 14.86. The boletus fucomannan and the composition containing the boletus fucomannan and the composition containing the boletus fucomannan and the composition containing the boletus fucomannan have the effects of promoting proliferation of beneficial bacteria, reducing the pH value of a microenvironment, increasing secretion of SCFAs and lactic acid, adjusting composition of intestinal microorganisms and the like, and have the function of improving the intestinal microecology. Therefore, the invention also discloses the fucomannan-glucomannan of the boletus roseus and the fucomannan-glucomannan of the boletus roseus and the fucomannan-glucomannan of the boletus roseus and the fucomannan-glucomannan of the boletus roseus and the fucomannan of the composition of the boletus roseus and the fucomannan of the composition of the boletus roseus and the fucomannan of the composition of the boletus roseus and the fucomannan of the composition of the composition of the composition of the composition of the composition of the composition of the composition of

This invention discloses a composition for enhancing immunity through gut microbiota, its preparation method, and its application. The composition comprises the following raw materials: a complex prebiotic, polyphenols, inactivated *Saccharomyces boulardii*, and plant extracts. The complex prebiotic includes human milk oligosaccharides and arabinogalactan, the polyphenols include berry polyphenols and grape polyphenols, and the plant extracts include pomegranate seed extract and kale extract. This invention's composition, on the one hand, selectively enriches *A. AKK* bacteria through prebiotics; *A. AKK* can directly interact with various immune cells to enhance immunity. On the other hand, supplementing with yeast factors can also inhibit inflammation and enhance immune responses, thereby significantly increasing the number of *A. AKK* bacteria in the gut microbiota and simultaneously improving intestinal cellular immune function.

The present application belongs to the technical field of application of fungal polysaccharides, and particularly relates to a Boletus edulis fruiting body polysaccharide as well as a preparation method and application thereof. Polysaccharides in Boletus edulis fruiting bodies are extracted, and the chemical structure of BDP-F is characterized by ultraviolet-visible light, Fourier transform infrared spectroscopy, one-dimensional nuclear magnetic resonance and two-dimensional nuclear magnetic resonance. The research results show that BDP-F is mainly composed of mannose, glucose, galactose and fucose. Methylation and nuclear magnetic resonance analysis show that the glycosidic bond of BDP-F is (1→6)-alpha-d-galactose, the main chain is composed of ->6)-alpha-d-galp-(1→ residues, and the O-2 position is branched by alpha-L-Fucp-(1→ and alpha-D-Manp-(1→ residues. Through DPPH free radical, hydroxyl radical and superoxide anion radical scavenging experiments, it is shown that BDP-F has the ability to serve as a natural antioxidant, and BDP-F can also reduce alcohol-induced GES-1 cell damage through antioxidant and anti-inflammatory effects within the experimental concentration range.

The invention provides a method for improving the stability of dehalogenase through an arabinogalactan covalent cross-linking immobilization technology. The method comprises the steps of constructing and expressing a recombinant dehalogenase strain, purifying the recombinant dehalogenase and carrying out dehalogenase covalent cross-linking immobilization. The arabinogalactan is used for covalently crosslinking the dehalogenase, so that the thermal stability of the dehalogenase and the stability of the dehalogenase under different pH conditions and in an organic solvent can be remarkably improved.

The present invention relates to a method for detecting glycosidic bonds of plant polysaccharides. The method includes taking 100 μL of NaOH-DMSO suspension (1 mg / mL) of plant polysaccharides containing 20 or more kinds of substances such as galactan, araban, polygalacturonic acid, rhamnogalacturonan-I, rhamnogalacturonan-II, xyluronic acid, arabogalacturonic acid I and arabogalacturonic acid II, shaking at room temperature for 30 minutes, adding 40 μL of iodomethane and shaking for 1 hour. Such process is repeated three times to obtain methylated plant polysaccharides. The method further includes using an automatic detection equipment for methylation combined with PMP derivatization to analyze glycosidic bonds in polysaccharides. Not only the glycosidic bond information of neutral sugars can be analyzed in the subsequent LC-MS mass spectrometry analysis, but also the glycosidic bond information of acidic sugars can be resulted, and the analysis results are faster, more detailed and more reliable.

The invention belongs to the field of biological medicine, and particularly relates to an antiviral composition and application thereof. The invention discloses an antiviral effect of breast milk oligosaccharide and arabinogalactan and an antiviral mechanism of the breast milk oligosaccharide and arabinogalactan. The invention also discovers that the compound polysaccharide composed of 2 '-fucosyllactose and arabinogalactan at low concentration can play a role in inhibiting influenza virus, the 2'-fucosyllactose and arabinogalactan play a synergistic effect, and the synergistic effect is associated with the drug concentration and the proportional relationship of the 2 '-fucosyllactose and arabinogalactan. According to the related discovery, the compound polysaccharide can be used for preparing foods, dietary nutrition supplements and medicines to improve the antiviral ability and immunity of subjects.

The invention discloses an induction substrate, a preparation method thereof, an application of the induction substrate in galactanase production and an enzyme preparation, and belongs to the technical field of microbial fermentation. The induction substrate provided by the invention is a product obtained by carrying out selective hydrolysis and post-treatment on Arabic gum or arabinogalactan through an acid-ethanol solution. The preparation method of the induction substrate comprises the steps of preparing the acid-ethanol solution, feeding, carrying out selective hydrolysis, neutralizing, precipitating, washing, drying and the like. The invention also provides a method for efficiently fermenting and producing the galactanase by using the induction substrate at a specific opportunity (the glucose concentration of fermentation liquor is lower than 0.2 g / L) and combining two-stage temperature control, and an enzyme preparation obtained by the method. The induction substrate is high in specificity, the yield of the beta-1, 6-galactanase can be remarkably increased, the raw materials are cheap, the process is simple, and the induction substrate is very suitable for industrial production.

The invention belongs to the technical field of high polymer materials, and discloses a design method of rare earth-polysaccharide based multifunctional hydrogel. The hydrogel takes arabinogalactan as a matrix and specifically comprises the following components: arabinogalactan, acrylamide, polyethylene glycol and nano copper powder, and europium ions are doped in the formed polysaccharide-based hydrogel. The hydrogel has fluorescent and conductive dual sensing channels, overcomes the disadvantage that the traditional rare earth hydrogel can only be used as a fluorescent sensor, and provides a stronger network and enhances mechanical properties by taking rare earth-polysaccharide as physical crosslinking. Meanwhile, the hydrogel can freely adjust the mechanical property and the fluorescence intensity by changing the polysaccharide content, responds to the external ion environment, and has extremely high sensing sensitivity (GF = 21) and tensile property (strain = 1100%). The hydrogel sensor is stable in performance and convenient to prepare, the application range of the rare earth hydrogel is widened, and the hydrogel sensor has a good development prospect.

The application discloses a method for preparing ganoderma polysaccharide rich in mannan-galactan structure by using a bacterium of the genus chryseobacterium GS-7 and ganoderma lucidum YJ0724 and application thereof, and relates to the technical field of microbial fermentation, and comprises the following steps: preparing a seed solution of the bacterium of the genus chryseobacterium GS-7 and a seed solution of the ganoderma lucidum YJ0724; a. inoculating the seed solution of the bacterium of the genus chryseobacterium GS-7 and the seed solution of the ganoderma lucidum YJ0724 into a fermentation medium at the same time for co-culturing to obtain a fermentation liquor containing ganoderma polysaccharide rich in mannan-galactan structure. The obtained ganoderma polysaccharide rich in mannan-galactan structure can improve immunoregulatory activity.

The invention discloses an anti-freezing and anti-oxidation compound agent for delaying quality deterioration of rinsing-reduced minced fillet in frozen storage and application of the anti-freezing and anti-oxidation compound agent, and belongs to the technical field of aquatic product processing. The invention relates to an anti-freezing and anti-oxidation compound agent for delaying quality deterioration of rinsing-reduced minced fillet in frozen storage. The anti-freezing and anti-oxidation compound agent comprises the following components in percentage by mass; the components comprise 30-40% of arabinogalactan, 0.005-0.01% of tea polyphenol and the balance of water; when in use, the arabinogalactan is dissolved in water, and the tea polyphenol is added after high-speed shearing treatment. The compound agent can reduce freezing denaturation caused by ice crystal formation and protein aggregation in the freezing storage period of rinsed surimi, reduce surimi quality deterioration caused by fat and protein oxidation, and effectively prolong the shelf life of the surimi.

The application discloses a marine red alga polysaccharide extract and application thereof, and belongs to the technical field of marine organisms and medicines. Gigartina radula The polysaccharide extract is extracted from marine red algae, and the main component is natural galactosamine sulfate, contains galactose and glucose, has a sulfate content of 20-40%, a 3,6-endo ether galactose content of 20-50%, and a viscosity of 80-400 mPa s. The polysaccharide extract contains kappa-carrageenan structural units, iota-carrageenan structural units, mu-carrageenan structural units, nu-carrageenan structural units and lambda-carrageenan structural units, and the proportion of the lambda-carrageenan structural units is 10-50%. The marine red alga polysaccharide extract can be applied to the preparation of medicines or functional skin care products for preventing and / or treating inflammatory and immune-related skin diseases such as atopic dermatitis AD.

Compositions, nutritional compositions and uses for modulating intestinal flora are provided. The composition for adjusting intestinal flora comprises the following components in parts by weight: 16-33% of fructo-oligosaccharide, 16-33% of arabinogalactan, 16-33% of a plant composition, 0-25% of inulin, 0-25% of galactooligosaccharide and 0-25% of chitosan oligosaccharide, and the plant composition comprises ginseng powder and a water extract prepared from the following raw materials in parts by weight: 1-10 parts of astragalus membranaceus, 1-10 parts of cinnamon, 1-10 parts of liquorice and 1-10 parts of fresh ginger. The weight ratio of the ginseng powder to the water extract is (50: 1)-(200: 1), and the weight ratio of the ginseng powder to the water extract is (50: 1)-(200: 1).

The invention belongs to the technical field of biological medicines, and particularly relates to a synthesis method of mycobacterium tuberculosis arabinogalactan 92-mer and a substructure thereof. Aiming at the technical problems of potential aglycone transfer and the like of an orthogonal one-pot glycosylation reaction strategy based on thioglycoside in the prior art, the mycobacterium tuberculosis arabinogalactan 92-mer and a substructure thereof are modularly and efficiently synthesized based on a one-pot glycosylation reaction strategy of glycosyl ortho (1-phenyl vinyl) benzoate (PVB).

The invention provides a new boletus theabrowns fucoidan mannogalactan, a composition thereof, a preparation method and application thereof, and belongs to the technical field of biological medicine mass health. The new boletus theabrownus fucoidan mannogalactan has a structure represented by a general formula in an attached drawing of the abstract, and n represents the number of sugar repeating units and is a natural number. The weight-average molecular weight of the new boletus theabrowns fucose mannogalactan is 10 kDa to 20 kDa, the polydispersity coefficient is 1 to 2, and the molar ratio of mannose to fucose to galactose is 1.00: 1.16: 3.85. The neo-boletus theabrown fucoidan mannan galactan and the composition containing the neo-boletus theabrown fucoidan mannan galactan have the effects of promoting proliferation of beneficial bacteria, reducing the pH value of a microenvironment, increasing secretion of SCFAs and lactic acid, regulating the composition of intestinal microorganisms and the like, and have the function of improving the intestinal microecology. Therefore, the invention also discloses the neo-boletus theabrownus fucoidan and a composition containing the neo-boletus theabrownus fucoidan, and application of the neo-boletus theabrownus fucoidan and the composition in preparation of prebiotic drugs and / or food for improving intestinal microecology, regulating intestinal flora and promoting intestinal health.

The present invention relates to a composition comprising at least one oxazoline, such as OX100, for inhibiting the growth of Malassezia yeasts and / or for preventing and / or treating conditions caused by Malassezia yeasts, seborrheic dermatitis, cradle cap, Malassezia folliculitis, dandruff, Pityriasis versicolor or Pityriasis capitis. The present invention also relates to a composition comprising at least one oxazoline such as OX100, at least one compound such as malic acid diester and a vegetable oil oleodistillate and / or arabinogalactan, and to the use of same for preventing and / or treating, in particular, affections caused by Malassezia yeasts, seborrheic dermatitis, cradle cap, Malassezia folliculitis, dandruff, Pityriasis versicolor or Pityriasis capitis.

The invention provides a low-branched-chain beta-(1, 3)-D-galactan with high main chain bond content and a synergistic enzyme method preparation method thereof, and belongs to the technical field of preparation of glycans with specific structures. According to the method, larch arabinogalactan is used as a substrate, a compound enzyme system composed of beta-(1, 6)-D-galactanase and alpha-1, 3-arabinosidase from penicillium oxalicum is used for carrying out synergistic and directional enzymolysis on the larch arabinogalactan, so that beta-(1, 6)-D-galactose side chains and connected arabinose are effectively removed, and the yield of the larch arabinogalactan is increased. Thus, beta-1, 3-galactan with a complete main chain and obviously reduced branched chains is obtained. The low-branched-chain beta-(1, 3)-D-galactan prepared by the invention can be used in the fields of immunomodulators, functional food additives and the like, and has the effects of remarkably enhancing immunocompetence, improving intestinal health and the like.

The invention relates to the technical field of coal mine underground dustproof materials, in particular to a coal mine underground dust suppression material as well as a preparation method and a dustproof method thereof. According to the dust suppression material, iohexol, citraconic acid and arabinogalactan serve as main raw materials, the adding proportion of all the raw materials is adjusted in a targeted mode, covalent bond connecting molecules are constructed through step-by-step esterification reaction, the water content of the obtained material can reach 6% in the high-temperature environment of 40 DEG C for 16 h, the hardness of a curing layer reaches 81.82 HA, the dust suppression efficiency at the wind speed of 15 m / s reaches up to 89.25%, and the dust suppression effect is good. The remarkable effect of lasting dust suppression under the high-temperature severe condition is achieved, and the key problems that a high-temperature underground dust suppressant is short in service life and prone to failure are solved.

The invention relates to a laver lysing extract as well as a preparation method and application thereof, and belongs to the technical field of biology. According to the method, a strain is obtained from a separating medium in the porphyra yezoensis drying processing process, it is tested that the strain can secrete lysozyme capable of rapidly dissolving porphyra cell walls, the lysozyme comprises amylase and protease, and intracellular phycobiliprotein, low-molecular sulfuric acid galactan and the like can be released after cell dissolution; the purpose that laver cells are lysed and intracellular components are efficiently released is achieved, and the strain is identified as bacillus tequilensis T7. The laver lysate extract prepared by the invention has the effects of resisting oxidation, preventing ultraviolet radiation and the like, and can be applied to the fields of cosmetics, functional foods, beverages and the like.

The application belongs to the field of medicine and relates to a preparation method and application of arabinogalactan in larch; wherein the arabinogalactan derivative in larch is sulfated arabinogalactan, and the sulfated arabinogalactan can be applied in the preparation of a medicine for treating inflammatory bowel disease or colon cancer; the sulfated arabinogalactan mainly regulates NCOA4-mediated ferritin autophagy by activating the AMPK-mTOR signal pathway and increases the relative abundance of Limosilactobacillus reuteri strain HDB1243 and Lactobacillus johnsonii strain 1696 to antagonize colon cancer, thereby providing a new means for the treatment of colon cancer.

The invention discloses a high-activity sparassis crispa culture medium capable of slowing down strain degradation, and relates to the technical field of sparassis crispa strain preservation, propagation and strain preparation. The sparassis crispa culture medium comprises a basic culture medium and a polysaccharide carbon source, wherein the polysaccharide carbon source is one or a mixture of more of glucomannan, xylan, soybean oligosaccharide and galactan. The polysaccharide is used as a main carbon source to replace monosaccharide in a conventional culture medium, so that the expression quantity of enzyme genes related to degradation of sparassis crispa hypha cellulose and hemicellulose in the culture period can be remarkably improved, the strain activity is improved, and strain degradation is slowed down. The sparassis crispa culture medium is simple in formula, high in stability, simple and easy to implement, and has important significance for maintaining stability and high activity of sparassis crispa strains.

This invention provides a filamentous fungus in which wall growth formation is suppressed, and the use of said filamentous fungus. [Solution] Use a filamentous fungus lacking one or more genes selected from the galactosaminogalactan biosynthesis gene group and one or more genes selected from the chitin biosynthesis gene group, or a filamentous fungus in which the expression of one or more genes selected from the galactosaminogalactan biosynthesis gene group and one or more genes selected from the chitin biosynthesis gene group is suppressed.

The invention relates to bi-crosslinking hydrogel as well as a preparation method and application thereof, and belongs to the technical field of polymer functional materials. According to the bi-crosslinked hydrogel, phenylboronic acid grafted carboxymethyl chitosan serves as a core skeleton, a first crosslinked network is formed by boric acid ester bonds and procyanidine, and a second crosslinked network is formed by Schiff base bonds and oxidized arabinogalactan. A composite network structure is constructed by integrating chemical crosslinking and physical crosslinking, the mechanical property, self-repairing property and environmental response stability of the hydrogel material are remarkably improved, and efficient drug loading and releasing are achieved through physical adsorption and chemical bonding of a three-dimensional network; besides, oxidized ferulic acid nanoparticles are loaded in the hydrogel, so that the oxidation resistance and the antibacterial effect are further improved, and the hydrogel has a wide application prospect in treatment of inflammatory and infectious skin diseases such as chronic refractory wounds and the like.

To provide a selective nanostructure delivery system for targeting an inhibitor of the PKC signaling pathway into the liver for use in the treatment of septic cholestasis.SOLUTION: The selective nanostructure delivery system comprises a carbohydrate targeting moiety and a PKC signaling pathway, wherein the inhibitor of the PKC signaling pathway is covalently linked, directly or through a linker or spacer moiety, to the carbohydrate targeting moiety, wherein the carbohydrate targeting moiety is selected from the group consisting of N-acetylgalactosamine (GalNAc), galactose, lactose, mannose, glucosamine, asialofetuin, pullulan, arabinogalactan, arabinoglycan, fuconic acid, lactobionic acid, transferrin, sitosterol glycoside (sitoG), glycyrrhizin, and glycyrrhetinic acid.SELECTED DRAWING: Figure 1

The invention discloses a preparation method of low molecular weight glucogalactan ANP-1 separated from notopterygium root. The ANP-1 is prepared by adopting a method of combining acid extraction with DEAE-52 cellulose ion exchange chromatography and Sephadex G-100 gel filtration chromatography. The molecular weight of the polysaccharide is 4.3 kDa, the main chain is formed by connecting-> 4)-alpha-D-Glcp-(1 <->), and the polysaccharide contains a characteristic-> 3)-beta-D-Galp-(1 <->) branched chain structure. Compared with WNP-1 and WNP-2 prepared by water extraction, the ANP-1 disclosed by the invention has better in-vivo and in-vitro hypoglycemic activity, and the problems of poor water solubility and low bioavailability of notopterygium polysaccharide are effectively solved. The action mechanism of the compound is closely related to the inhibition of IL-6-mediated inflammatory response and the resistance to oxidative stress. The invention provides a new natural drug candidate for prevention and improvement of type 2 diabetes mellitus.