69 results about "Diselenide" patented technology

The invention provides a preparation method of an alpha-difluoroselenomethyl ketone derivative, which is a method for preparing the alpha-difluoroselenomethyl ketone derivative by using 2, 2-difluoroolefin and dialkyl diselenide in the presence of iodosobenzene diacetate. The preparation method specifically comprises the following steps: dissolving 2, 2-difluoroolefin and a dialkyl diselenide compound in an organic solvent, uniformly mixing, adding iodobenzene diacetate, and stirring and reacting at a certain temperature in an air atmosphere to obtain the product alpha-difluoro (seleno) methyl ketone derivative. The alpha-difluoroselenomethyl ketone derivative can be mildly and efficiently obtained by only adopting iodobenzene diacetate without necessary catalysts, alkali, persulfide and persulfate compounds in the prior art. Wherein R1 and R2 are aliphatic hydrocarbon, substituted and unsubstituted benzene, substituted and unsubstituted naphthalene or other aromatic groups.

The invention belongs to the technical field of organic synthetic chemistry, and particularly relates to a preparation method and medical application of a visible-light-driven bis (trifluoromethyl) selenide compound. The preparation method of the bis (trifluoromethyl) selenide compound comprises the following steps: by taking olefin, trifluoromethylselenotetramethylammonium and bis (trifluoromethylseleno) diselenide as reaction raw materials, stirring and reacting under the conditions of proper temperature and visible light irradiation in the presence of cuprous salt to obtain the bis (trifluoromethyl) selenide compound. The method has the advantages of mild reaction conditions, simplicity and convenience in operation, good functional group compatibility and the like. In addition, the bis (trifluoromethyl) selenide compound provided by the invention shows good potential in the aspect of anticonvulsion, and has the prospect of being further developed into anticonvulsion drugs.

The application belongs to the technical field of two-dimensional thin film material growth and preparation, and discloses a kind of platinum diselenide and its preparation method and application, the morphology of the platinum diselenide is square single crystal, nanostructure with dendritic characteristics, sheet or continuous film.The application is innovative in morphology and product form, not only prepares platinum diselenide with square single crystal morphology, but also creates favorable conditions for fully exerting its potential different optoelectronic device applications, and can realize controllable preparation of square single crystal, nanostructure with dendritic characteristics, sheet and continuous film morphology through simple parameter adjustment.In terms of process compatibility, with low-temperature preparation process, the temperature limitation of traditional high-temperature method is effectively avoided, and the limitation of crystal domain size in traditional low-temperature method is broken through, and crystal lateral size meeting the actual application requirements can be obtained, providing a key guarantee for adaptation with existing processes.

The invention discloses a room-temperature DMMP sensor based on a platinum diselenide van der Waals heterojunction, and relates to the technical field of gas sensing. The sensor comprises an electrode, a platinum diselenide layer loaded on the surface of the electrode and a nano material loaded on the surface of the platinum diselenide layer, wherein the platinum diselenide layer and the nano material form a Van der Waals heterojunction; wherein the nano material is a low-dimensional nano material such as a carbon nano tube, graphene, zinc oxide, molybdenum disulfide or tungsten disulfide. The platinum diselenide / Van der Waals heterojunction sensor realizes trace detection of dimethyl methylphosphonate (DMMP) at room temperature by using excellent performance of platinum diselenide and a synergistic effect of the Van der Waals heterojunction, has the advantages of low working temperature, high sensitivity, good stability, high response speed and the like, and can meet DMMP detection requirements in the fields of environmental monitoring, public safety and the like.

The invention discloses a lead-free copper-based self-lubricating composite material and a preparation method thereof, and relates to the technical field of self-lubricating bearing materials. The lead-free copper-based self-lubricating composite material comprises the following components in percentage by weight: 5%-10% of Sn, 0.5%-5% of Si, 1%-6% of selenide and the balance of Cu, and the selenide is selected from one or a combination of two of molybdenum diselenide and niobium diselenide. The comprehensive performance of the lead-free copper-based self-lubricating composite material is remarkably improved through material system design, the mechanical performance and service reliability are outstanding, the service cycle of a copper-based sliding bearing can be effectively prolonged, and compared with a traditional lead-containing material, the lead-free copper-based self-lubricating composite material has higher performance and environment friendliness and is suitable for being applied to bearings under extreme working conditions.

A novel organic diselenide composition comprises 1,2-bis(4-vinylbenzyl) diselane. The organic diselenide composition may be incorporated with one or more polymers through a chemical bonding process for utilization as an agent against infectious, disease-causing agents.

The application discloses a selenoglycoside compound and a synthesis method, and aims at a series of technical defects in the existing selenoglycoside synthesis technology, such as high reagent toxicity, strong irritability, poor stability, harsh reaction conditions, complicated operation, insufficient stereoselectivity, poor substrate universality and difficulty in industrial application, and provides a green and efficient selenoglycoside compound synthesis method with strong universality, which has remarkable beneficial technical effects. The core reaction substrate adopted in the application is a glycosyl selenosulfonate and a (hetero) aryl boronic acid, both of which are conventional reagents easy to obtain, have no irritating odor, and have excellent chemical stability and environmental tolerance, thereby avoiding the use of high-toxicity, high-irritability and low-stability reagents such as diselenide, selenol and glycosyl stannane in the traditional synthesis process from the source, greatly reducing the safety control cost and three-waste treatment pressure in the synthesis process, and meeting the development requirements of green chemistry.

This invention relates to a method for preparing and applying a ternary heterostructure nanosheet of tungsten diselenide / tin diselenide / tin monoselenide, belonging to the field of gas sensor technology. The invention discloses a ternary heterostructure nanosheet of tungsten diselenide / tin diselenide / tin monoselenide and its application as a sensing material in a highly selective and sensitive flexible NO2 gas sensor. The invention utilizes a liquid-phase growth method, using SnSe2 nanosheets, ammonium tungstate, and diphenyldiselenoether as raw materials, and varying reaction conditions such as temperature, reaction time, and raw material content to prepare the ternary heterostructure nanosheet of tungsten diselenide / tin diselenide / tin monoselenide. Subsequently, these nanosheets are sprayed onto interdigitated electrodes and dried to form a film, thus preparing a chemielectric resistive gas sensor capable of detecting low concentrations of nitrogen dioxide gas at room temperature. It not only possesses high sensitivity and selectivity but can also be applied to flexible NO2 gas sensing.

The application belongs to the field of electronic components, and particularly relates to a MCM-1A type high-frequency metal packaging mica capacitor. The capacitor is composed of a metal packaging shell, a core group in the shell is fixed by a silver-plated metal gasket, and the core group is composed of multiple pieces of white mica sheets printed with electrodes and silver-plated metal lead-out sheets alternately stacked. A dielectric topological insulator heterojunction composite nanomaterial is introduced into the silver-plated metal gasket. The material takes a bismuth diselenide nanosheet as a core, coats a barium strontium titanate shell through an atomic layer deposition process, and is modified through surface polymer coating. The composite nanomaterial effectively optimizes the interface characteristics and high-frequency conductivity of the electrode. The capacitor has a simple preparation process, is compatible with the existing production line, has lower loss and higher temperature stability at high frequency, and is suitable for high-frequency circuits.

The invention relates to the technical field of high polymer materials, and discloses a transparent invisible orthodontic appliance material with an antibacterial function and a preparation process thereof, and the transparent invisible orthodontic appliance material is characterized in that a selenium-containing monomer, a fluorine-containing amphoteric monomer and a sacrificial metal coordination network are introduced into a thermoplastic polyurethane main chain. In the preparation process, a hot shear field of melt extrusion is used for driving fluorine-containing amphoteric groups to segregate on the surface, and a wet hydrophilic anti-adhesion layer is formed; a physical cross-linked network is constructed through metal coordination, modulus compensation is provided, and the material is endowed with mechanochemical response characteristics. When the appliance is stressed, the sacrificial coordination bond is broken to release metal ions, the diselenide bond is catalyzed to efficiently generate active oxygen, and antibacterial enhancement of a stressed area is realized. The material disclosed by the invention has the synergistic functions of high transparency, excellent obdurability, microcrack self-repairing and anti-adhesion intelligent sterilization, and effectively solves the problems that the invisible appliance is easy to breed bacteria and the mechanical property is degraded.

The invention relates to the technical field of nano medicines, and discloses an ATP / cerium coordination polymer nano regulator as well as a preparation method and application thereof. The invention relates to an ATP / cerium coordination polymer nano regulator. The invention relates to a self-assembly hydrogel which is prepared from raw materials including cerous nitrate (III), adenosine-5 '-disodium triphosphate, phospholipid polyethylene glycol amino, SS31 peptide and a diselenide cross-linking agent through a self-assembly and cross-linking method, can effectively remove ROS (reactive oxygen species) in an inner ear and protect cells from oxidative stress injury, thereby protecting auditory cells and improving the quality of the inner ear. The traditional Chinese medicine composition has the effect of treating hearing loss caused by oxidative stress induced by noise, can be used for treating hearing loss through middle ear cavity local administration, is simple in preparation method and mild in reaction condition, and can realize large-scale production. Cascade catalysis of cerium (III) and cerium (IV), ATP (adenosine triphosphate) energy supply and a nano system of a selenium biological material are utilized, and a novel method is provided for treating noise-induced hearing loss.

The present invention provides a hydrogel for comprising a biodegradable polyphosphazene polymer, a radiation-sensitive diselenide cross-linker; and one or more payloads releasably loaded within the hydrogel. The present invention further provides methods for radiosensitizing target tissues such as tumors and providing sustained delivery of therapeutics triggered by irradiation. In another aspect, the present invention provides a method that includes: introducing the hydrogel, as describes herein, adjacent to malignant or marginal tissue; and administering radiation to the hydrogel, thereby disrupting the selenocystamine cross-linkers and releasing the one or more payloads.

The application discloses a preparation method of germanium diselenide and belongs to the technical field of compound preparation. The preparation method of germanium diselenide provided by the application comprises the following steps: mixing germanium powder screened and selenium powder screened and ball milling, then heating and reacting in an inert gas environment, crushing after removing the surface attachments of the heating and reaction product, and heat-insulating and reacting in the inert gas environment, so that golden yellow crystalline germanium diselenide can be obtained. The obtained germanium diselenide is high in purity, free of segregation, and low in loss, namely, high in yield. Moreover, the preparation method provided by the application is simple in operation, does not need special equipment, and is beneficial to practical production and application.

The invention discloses a method for synthesizing selenocyclopentene by electrochemical catalysis of cyclization reaction of terminal alkyne, acrylate and diselenide [3 + 2], and belongs to the technical field of organic synthesis.The method comprises the steps that the terminal alkyne, allyl dimethyl ester and diselenide serve as raw materials, cheap ferrocene serves as a redox catalyst under the electrochemical condition, and the selenocyclopentene is synthesized through the cyclization reaction of the terminal alkyne, the acrylate and the diselenide [3 + 2]; the selenium-containing cyclopentene skeleton is efficiently constructed. According to the method for synthesizing selenocyclopentene through the cyclization reaction of terminal alkyne, acrylate and diselenide [3 + 2] through electrochemical catalysis, the reaction condition is mild, no additional oxidizing agent is needed, the substrate applicability is wide, the functional group compatibility is good, and the target product can be obtained with the medium to excellent yield.

The application discloses a kind of high selectivity β-triazole (β-triazole trifluoromethyl, β-triazole ketone, β-triazole thio, β-triazole selenide) Derivative and its synthesis method and application, with triazole compound, alkyl compound / aldehyde / dithioether / diselenide and styrene as raw material, in oxidant, additive and organic solvent, through one step reaction can high selectivity, high yield product is obtained.The method of the application has the advantages of good selectivity, mild reaction condition, high yield, simple and safe operation and high efficiency etc.The β-triazole ketone derivative compound involved in the application is a kind of new structure, has good anti-osteosarcoma activity, biological activity analysis shows that part of compounds can reach 99% inhibition rate to osteosarcoma (OS) cell line 143B, MNG / HOS and SJSA-1 at 10 μM concentration.Therefore, the compound can be used as important pharmaceutical and chemical intermediates, and has wide application prospect in the field of medicine.

The application discloses a selenium-based pyrrolopyridazine compound and a preparation method and medical application thereof. The structure of the compound is shown as formula (I). The preparation method of the compound is as follows: 1-amino pyrrole, aryl formaldehyde, diaryl diselenide and disubstituted acetylene are used as raw materials in an organic solvent, under the protection of nitrogen, in the presence of a rhodium catalyst and a copper salt, and heating reaction can obtain the selenium-based pyrrolopyridazine compound. The method has the advantages of high functional group tolerance and simple operation. In addition, the activity test results show that the selenium-based pyrrolopyridazine compound prepared by the application exhibits significant inhibitory activity on JAK1 and JAK3 kinases, has a good clinical development prospect, and can be used for preparing a medicine for preventing and / or treating rheumatoid arthritis.

The application provides a ferrous diselenide rod-shaped nanoflower nitrogen-doped carbon material and a preparation method and application thereof, and belongs to the technical field of battery materials. The prepared iron selenide presents a nanoflower structure composed of nanorods, and an outer layer is covered by a nitrogen-doped carbon shell, and is a kind of self-assembled nanoflower composite material. The nanoflower structure increases the specific surface area of the material, provides abundant active sites for catalysis, the nitrogen-doped carbon shell enhances the physical confinement of polysulfides and the transmission of electrons, there is a strong chemical bond between FeSe2 and polysulfides, which can effectively anchor polysulfides, and can accelerate the catalytic conversion of polysulfides and relieve the shuttle effect. The lithium-sulfur battery using the material as a positive active material has excellent cycle stability and high sulfur loading.

The present application relates to the technical field of chemical synthesis, in particular to a double selenium compound, a selenium-containing film and a preparation method thereof.The double selenium compound has a structure of formula (I).The preparation method comprises the following steps: mixing a compound of formula (II) and an inorganic diselenide to obtain the compound of formula (I).The present application takes the double selenium compound as a core raw material, and combines a substrate and optional reagents such as a reducing agent, a base, a melanin precursor and an oxidizing agent to prepare a selenium-containing film under mild conditions.The present application solves the synthesis problem of integrating catechol and diselenide bond and the application bottleneck of uneven distribution of selenium components and weak binding force in the selenium-containing film, and the product has good adhesion and stability, and has a wide application prospect.

The application belongs to the technical field of lubricating materials, and particularly relates to a self-lubricating composite material and a preparation method and application thereof. The self-lubricating composite material provided by the application comprises a base body and a lubricant dispersed in the base body; the material of the base body is an alloy powder; the lubricant comprises a lubricating material and a binder, the lubricating material comprises one or more of graphite, molybdenum disulfide, tungsten disulfide, niobium diselenide, boron nitride, silver and eutectic fluoride; and the size of the lubricant is 100-1000 microns. The lubricant is distributed in the form of isolated islands in the base body of the composite material, forming a unique macrostructure, and the metal base bodies are connected to each other to form a continuous whole, thereby effectively avoiding the splitting effect of the traditional micro-lubricating phase on the base body due to the dispersed distribution, and improving the mechanical properties; in the friction process, the lubricant can continuously and stably release the lubricating material to the friction interface as a discrete lubricating unit, and spread to form a continuous and uniform lubricating film, thereby realizing long-acting self-lubrication.

The application discloses a preparation method of a self-supporting catalyst of a nickel diselenide hierarchical nanoneedle array, and belongs to the field of new chemical material catalysis. The method comprises the following steps: dissolving nickel salt, cerium salt, urea and ammonium fluoride in deionized water, stirring and uniformly mixing, placing the mixture and carbon fiber paper in a reaction kettle to perform a hydrothermal reaction, naturally cooling to room temperature after the reaction is completed, taking out the carbon fiber paper, washing and drying, thereby preparing the carbon fiber paper loaded with a nickel precursor array, placing the carbon fiber paper loaded with the nickel precursor array in air to perform calcination, washing and drying the calcination product, adding deionized water and NaHSe solution, uniformly mixing, performing a hydrothermal reaction, naturally cooling to room temperature after the reaction is completed, taking out the carbon fiber paper, washing and drying, thereby obtaining the self-supporting catalyst of the nickel diselenide hierarchical nanoneedle array rich in nickel vacancies. The catalyst prepared by the method is applied to electrocatalytic hydrogen evolution, and the experimental results show that the catalyst has excellent hydrogen evolution performance and has a good application prospect in the field of electrocatalytic hydrogen evolution.

This invention provides a palladium diselenide / tungsten diselenide vertical heterojunction field-effect transistor, its fabrication method, and its application, belonging to the field of semiconductor device technology. The palladium diselenide / tungsten diselenide vertical heterojunction field-effect transistor comprises, from bottom to top, a substrate, a vertical heterojunction, and a metal electrode; the vertical heterojunction includes a tungsten diselenide layer covering the substrate and a palladium diselenide layer covering the tungsten diselenide layer. This invention first constructs a tungsten diselenide layer on the substrate using chemical vapor deposition (CVD), and then directly grows a palladium diselenide layer on the surface of the tungsten diselenide layer using CVD. This vertical heterojunction field-effect transistor exhibits excellent performance with high saturation current density, high carrier mobility, and a high current on / off ratio, solving the technical problem of low performance and incompatibility with two-dimensional n-type semiconductor field-effect transistors in current two-dimensional p-type semiconductor devices.

The invention relates to the technical field of high polymer material modification, in particular to diselenide cellulose as well as a preparation method and application thereof. The invention provides diselenide cellulose. The diselenide cellulose is prepared from the following raw materials: cellulose, diisocyanate and bis (2-aminophenyl) diselenide. The diisocyanate and the bis (2-aminophenyl) diselenide are added into the cellulose for modification, so that the original extremely stable hydrogen bond network structure balance of the cellulose is broken, the dynamic reversibility of the hydrogen bond structure of the cellulose is realized, and the cellulose has self-repairing performance.

The invention belongs to the technical field of two-dimensional materials, and discloses a method for growing two-dimensional palladium diselenide and a field effect transistor prepared by using the two-dimensional palladium diselenide. The method comprises the following steps: S1, weighing Se powder and PdI2 powder, placing the Se powder and the PdI2 powder in a source region of a quartz tube, placing a substrate in a growth region of the quartz tube, and controlling the distance between the substrate and the neck of the quartz tube to be 4-7cm; vacuumizing and sealing the interior of the quartz tube; s2, putting the quartz tube into a tubular furnace, putting a source region of the quartz tube into a central region of the tubular furnace, and heating for reaction; and after the reaction is finished, taking out the quartz tube to obtain the two-dimensional palladium diselenide growing on the substrate. The controllable synthesis of the two-dimensional PdSe2 with a large transverse size and the construction of a field effect transistor are realized, and the single-layer and few-layer high-quality two-dimensional PdSe2 with a large transverse size and excellent performance is prepared. The field effect transistor prepared from the two-dimensional PdSe2 is excellent in performance.

The invention discloses a glassy polymer and a preparation method thereof, and a molded part and a preparation method thereof, and relates to the technical field of high polymer materials. The preparation method of the glassy polymer comprises the following steps: providing a first mixed solution and a second mixed solution, mixing, and carrying out a first reaction to obtain a hyperbranched prepolymer mixed solution; the first mixed solution comprises N, N-methylene bisacrylamide, and the second mixed solution comprises ethylenediamine; providing a third mixed solution and 3-bromopropylamine, mixing the third mixed solution and 3-bromopropylamine, and carrying out a second reaction to obtain diselenide; the third mixed solution comprises selenium powder; mixing diselenide and the hyperbranched prepolymer mixed solution, and carrying out a third reaction to obtain a glassy polymer; the glassy polymer prepared by the preparation method provided by the invention has excellent mechanical properties, keeps stable mechanical properties after repeated processing, has excellent room-temperature self-repairing performance, does not need external stimulation, and has wide application prospects in the fields of flexible electronic devices, transparent protective materials, engineering structural members and the like.

The application relates to the technical field of two-dimensional material preparation, and particularly relates to a PdSe2 wafer-level preparation method and application. The application verifies whether the temperature and gas flow rate in a tubular furnace are uniformly distributed in the selenization process by fluid dynamics simulation of the temperature and gas flow rate in the tubular furnace; verifies the influence of the selenization temperature on the synthesis of a PdSe2 film; verifies the influence of the precursor thickness on the preparation of PdSe2; and compares the influence of the temperature and thickness on the quality of PdSe2 synthesized by evaporating Pd metal through an electron beam and then selenizing to widen the growth parameter window. Finally, a high-performance PdSe2 wafer-level is prepared, and the preparation method is further applied to prepare a PdSe2 device, and a field effect transistor and a photoelectric detector are constructed. The application can provide an important reference for silicon process compatible preparation of a wafer-level high-quality PdSe2 two-dimensional material.

This invention relates to the field of batteries, and more particularly to a nitrogen-doped carbon / tungsten diselenide nanosphere composite material, its preparation method, and its applications. This invention achieves tight coupling between few-layer WSe2 nanosheets and a nitrogen-doped carbon framework through a process combining complexation-polymerization and subsequent selenization. The resulting material consists of nanosphere particles, providing more electrochemical active sites and shortening the zinc ion diffusion distance. By introducing a nitrogen-doped carbon framework, this invention effectively improves the overall conductivity of the composite material and suppresses the stacking and aggregation of WSe2 nanosheets during charge and discharge, thereby significantly improving rate performance and cycle stability.

The invention discloses a diselenide bond cross-linked polyethyleneimine carrier for mRNA (messenger Ribonucleic Acid) delivery as well as a preparation method and application of the diselenide bond cross-linked polyethyleneimine carrier. The preparation of the carrier comprises the following steps: taking a synthesized diselene-1, 6-hexanediol diacrylate monomer (DSEDA) as a diselenide cross-linking agent; the diselenide cross-linked polymer material is prepared from the diselenide and branched PEI with the molecular weight of 0.6 kDa / 1.8 kDa through the Michael addition reaction of amine-acrylate, non-cross-linked primary amine is subjected to hydrophobic / hydrophilic chain modification, the hydrophilic / hydrophobic chain is a compound CH2COO-R, and the substituent R is one or more of C8-C12 linear alkyl or 6-12 oligomers of polyethylene glycol. In the carrier structure, biodegradable diacrylate bonds and diselenide bonds are introduced into the cross-linking agent, so that the transfection efficiency is maintained, and meanwhile, the toxicity is reduced to the maximum extent. As the diselenide bond can sensitively respond to oxidation and reduction environments at the same time, the diselenide bond-containing polymer molecule can become a novel mRNA carrier material, and can play a promoting role in improving intracellular mRNA release and translation.

The invention belongs to the field of electronic components, and particularly relates to an MCM-1A type high-frequency metal packaging mica capacitor, which is formed by packaging core groups by pressing a metal packaging shell, and is characterized in that the core groups connected in parallel are fixed in the shell through silver-plated metal gaskets; and the core group is formed by alternately overlapping a plurality of muscovite sheets printed with electrodes and silver-plated metal lead-out sheets. A dielectric topological insulator heterojunction composite nano material doped in a silver-plated metal gasket is introduced, a bismuth triselenide nanosheet is used as a core of the material, a barium strontium titanate shell layer is coated outside the bismuth triselenide nanosheet through an atomic layer deposition process, and the bismuth triselenide nanosheet is coated and modified through a surface polymer. The composite nano material effectively optimizes the interface characteristics and high-frequency conductivity of the electrode. The capacitor is simple in preparation process and compatible with an existing production line, and the obtained product has lower loss and higher temperature stability under high frequency and is suitable for a high-frequency circuit.

The invention provides a multifunctional bioprosthetic valve material as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. According to the material, an acellular biological tissue matrix is used as a substrate, and formyl-free hydroxymethylated melamine is adopted for crosslinking to solve the calcification problem; an active oxygen response type intelligent hydrogel coating is constructed on the surface of the hydrogel, is composed of gelatin and diselenide bond-containing nanogel loaded with an anti-inflammatory drug, and can respond to an inflammatory microenvironment and intelligently release; through double-module cooperation of non-glutaraldehyde crosslinking and the intelligent response coating, the material has excellent anti-calcification and anti-thrombus performance, inflammation can be actively regulated and controlled, endothelialization is promoted, and the long-term durability and biocompatibility of the bioprosthetic valve are remarkably improved.

The invention discloses a high-sensitivity sensing film based on a niobium diselenide (NbSe2) layered material, and belongs to the technical field of optical devices. The high-sensitivity sensing film sequentially comprises a transparent substrate, a gold film and niobium diselenide sensitive coatings from bottom to top, and the number of layers of the niobium diselenide sensitive coatings is 1-6. The surface of the gold film is coated with niobium diselenide, and electrons in the niobium diselenide material can be transferred to the metal surface, so that the concentration of free electrons on the metal surface is enhanced, the electric field intensity of a sensing interface is improved, and finally the sensibilization effect is achieved.